• Title/Summary/Keyword: Constant potential

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The Abanones, Haliotis discus hannai, Exhibit Potential Anticoagulant Activity in Normal Sprague Dawley Rats (정상 Sprague Dawley 쥐에 대한 전복의 항응고능에 관한 효과)

  • Kim, Hag-Lyeol;Kim, Seon-Jae;Kim, Du-Woon;Ma, Seung-Jin;Gao, Tiancheng;Li, Hua;Lee, Tae-Hoon;Kim, In-Cheol;Ham, Kyung-Sik;Kang, Seong-Gook
    • Food Science and Preservation
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    • v.14 no.4
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    • pp.431-437
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    • 2007
  • The primary objective of this study was to determine the effects of abalone in reducing blood pressure and increasing anti-coagulant capacity. The serum angiotensin-converting-enzyme (ACE) activities of rats on an abalone-supplemented diet did not significantly differ from the ACE levels of rats on a normal diet, at any time (before the experiment, or 1 week, 2 weeks, 3 weeks, and 4 weeks, after commencement of the abalone diet) during the experiment. This result showed that abalone-supplemented diets had no effect on the activity of ACE, which controls blood pressure. To determine if an abalone-containing diet might increase anti-coagulant capacity, both prothrombin (PT) and activated partial thromboplastin time (APTT) levels were measured. The PT levels of control rats remained constant throughout the experiment. In rats fed the abalone-containing diet, PT levels increased with time, and the increase became statistically significant after 2 weeks, when compared to pre-trial PT levels. Control rats showed no significant change in APTT levels over time. The rats fed abalone, however, showed significant differences in APTT levels. Specifically, when pre-trial APTT levels were compared with 4-week levels, and when 1-week levels were compared with 4-week levels, the differences attained statistical significance. These results indicate that an abalone-supplemented diet may inhibit blood coagulation in normal rats. The results of this study prove the inherent health value of abalone, and may encourage investment in the seafood industry. Future studies will explore other possible beneficial effects of abalone, apart from the anti-hypertension and anti-coagulant effects examined above.

Effect of the Heat Treatment on the Mechanical Property and Corrosion Resistance of CU - 7Al - 2.5Si Alloy (Cu-7Al-2.5Si 합금의 기계적 및 내식특성에 미치는 열처리 효과)

  • Lee, Syung-Yul;Won, Jong-Pil;Park, Dong-Hyun;Moon, Kyung-Man;Lee, Myeong-Hoon;Jeong, Jin-A;Baek, Tae-Sil
    • Corrosion Science and Technology
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    • v.13 no.1
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    • pp.28-35
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    • 2014
  • Recently, the fuel oil of diesel engines of marine ships has been increasingly changed to heavy oil of low quality as the oil price is getting higher and higher. Therefore, the spiral gear attached at the motor of the oil purifier which plays an important role to purify the heavy oil is also easy to expose at severe environmental condition due to the purification of the heavy oil in higher temperature. Thus, the material of the spiral gear requires a better mechanical strength, wear and corrosion resistance. In this study, the heat treatment(tempering) with various holding time at temperature of $500^{\circ}C$ was carried out to the alloy of Cu-7Al-2.5Si as centrifugal casting, and the properties of both hardness and corrosion resistance with and without heat treatment were investigated with observation of the microstructure and with electrochemical methods, such as measurement of corrosion potential, cathodic and anodic polarization curves, cyclic voltammogram, and a.c. impedance. in natural seawater solution. The ${\alpha}$, ${\beta}^{\prime}$ and ${\gamma}_2$ phases were observed in the material in spite of no heat treatment due to quenching effect of a spin mold. However, their phases, that is, ${\beta}^{\prime}$ and ${\gamma}_2$ phases decreased gradually with increasing the holding time at a constant temperature of $500^{\circ}C$. The hardness more or less decreased with heat treatment, however its corrosion resistance was improved with the heat treatment. Furthermore, the longer holding time, the better corrosion resistance. In addition, when the holding time was 48hrs, its corrosion current density showed the lowest value. The pattern of corroded surface was nearly similar to that of the pitting corrosion, and this morphology was greatly observed in the case of no heat treatment. It is considered that ${\gamma}_2$ phase at the grain boundary was corroded preferentially as an anode. However, the pattern of general corrosion exhibited increasingly due to decreasing the ${\gamma}_2$ phase with heat treatment. Consequently, it is suggested that the corrosion resistance of Cu-7Al-2.5Si alloy can be improved with the heat treatment as a holding time for 48 hrs at $500^{\circ}C$.

Chromosome Analysis in Clinical Samples by Chromosome Diagnostic System Using Fluorescence in Situ Hybridization (국산 Fluorescence in Situ Hybridization 시스템을 이용한 다양한 검체에서의 염색체 분석)

  • Moon, Shin-Yong;Pang, Myung-Geol;Oh, Sun-Kyung;Ryu, Buom-Yong;Hwang, Do-Yeong;Jung, Byeong-Jun;Choe, Jin;Sohn, Cherl;Chang, Jun-Keun;Kim, Jong-Won;Kim, Seok-Hyun;Choi, Young-Min
    • Clinical and Experimental Reproductive Medicine
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    • v.24 no.3
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    • pp.335-340
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    • 1997
  • Fluorescence in situ hybridization (FISH) techniques allow the enumeration of chromosome abnormalities and from a great potential for many clinical applications. In order to produce quantitative and reproducible results, expensive tools such as a cooled CCD camera and a computer software are required. We have developed a Chromosome Image Processing System (Chips) using FISH that allows the detection and mapping of the genetic aberrations. The aim of our study, therefore, is to evaluate the capabilities of our original system using a black-and-white video camera. As a model system, three repetitive DNA probes (D18Z1, DXZ1, and DYZ3) were hybridized to variety different clinical samples such as human metaphase spreads and interphase nuclei obtained from uncultured peripheral blood lymphocytes, uncultured amniocytes, and germ cells. The visualization of the FISH signals was performed using our system for image acquisition and pseudocoloring. FISH images were obtained by combining images from each of probes and DAPI counterstain captured separately. Using our original system, the aberrations of single or multiple chromosomes in a single hybridization experiment using chromosomes and interphase nuclei from a variety of cell types, including lymphocytes, amniocytes, sperm, and biopsied blastomeres, were enabled to evaluate. There were no differences in the image quality in accordance with FISH method, fluorochrome types, or different clinical samples. Always bright signals were detected using our system. Our system also yielded constant results. Our Chips would permit a level of performance of FISH analysis on metaphase chromosomes and interphase nuclei with unparalleled capabilities. Thus, it would be useful for clinical purposes.

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Determination of porosity and effective porosity of saturated porous media using a permittivity method in the laboratory (유전율법을 이용한 다공질 매질의 공극률 및 유효공극률의 측정에 관한 연구)

  • 김만일;니시가끼마코토
    • The Journal of Engineering Geology
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    • v.13 no.4
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    • pp.419-428
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    • 2003
  • In order to evaluate groundwater movement and the infiltration of contaminants, such as petroleum products, the determination of porosity and effective porosity is very important. Porosity and effective porosity are important physical parameters that determine the transfer and movement of water and solutes in porous media. Various methods of determining these parameters have been developed, with varying degrees of accuracy and applicability. Most of the existing methods produce static results. They do not produce instantaneous and real time of porosity and effective porosity in a porous media. In this study, we used a new permittivity method called Frequency Domain Reflectometry with Vector analyzer (FDR-V) to determine the porosity and effective porosity of some sand samples in the laboratory. The advantage of the FDR-V method is that it instantaneously determines the temporal variation of dielectric constants of porous media. Then, the porosity and the effective porosity of porous media are computed using well established empirical equations. Results obtained from the FDR-V method compared favorably with results from other permittivity methods such as gravimetric, injection and replacement tests. The ratio of effective porosity to porosity was 85 - 92 %, when FDR-V was used. This value compared favourably with 90 %, which has been usually quoted in previous studies. Considering the convenience and its applicability, the EDR-V permittivity holds a great potential in porous media and contaminant transport studies.

Temperature Effect on the Swelling Pressure of a Domestic Compacted Bentonite Buffer (국산 압축벤토나이트 완충재의 온도에 따른 팽윤압 특성 연구)

  • Lee, Ji-Hyeon;Lee, Min-Soo;Choi, Heui-Joo;Choi, Jong-Won
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.8 no.3
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    • pp.207-213
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    • 2010
  • The effect of temperature on swelling pressure was observed with a Korean domestic Ca-bentonite which has been considered as a potential buffer material in the engineering barrier of a high level radioactive waste (HLW) disposal system. The Ca-bentonite was compacted to a dry density of 1.6 g/$cm^3$, and then de-ionized water was supplied into it with a constant pressure of 0.69 MPa. The equilibrium swelling pressures were measured with different temperatures of $25^{\circ}C$, $30^{\circ}C$, $40^{\circ}C$, $50^{\circ}C$, $60^{\circ}C$, $70^{\circ}C$, respectively. The Ca-bentonite showed a sufficiently high swelling pressure of 5.3 MPa at room temperatures. Then it was clearly showed that the equilibrium swelling pressure was decreased with an increase of temperature. Interestingly, there were some differences in temperature effect on the equilibrium swelling pressure when the environmental temperature is increasing or decreasing. For further clarifying the swelling behaviour of a Korea domestic Ca-bentonite, the change of a compaction level, and the composition variation of a supplied water would be needed to use in conceptual design of HLW disposal system.

A Case Study of Monitored Natural Attenuation at the Petroleum Hydrocarbon Contaminated Site : II. Evaluation of Natural Attenuation by Groundwater Monitoring (유류오염부지에서 자연저감기법 적용 사례연구 II. 지하수모니터링에 의한 자연저감 평가)

  • Yun Jeong Ki;Lee Min Hyo;Lee Suk Young;Noh Hoe Jung;Kim Moon Soo;Lee Kang Kun;Yang Chang Sool
    • Journal of Soil and Groundwater Environment
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    • v.9 no.3
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    • pp.38-48
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    • 2004
  • Natural attenuation of petroleum hydrocarbon was investigated at an industrial complex about 45 Km away from Seoul. The three-years monitoring results indicated that the concentrations of DO, nitrate, and sulfate in the contaminated area were significantly lower than the background monitoring groundwater under the non-contaminated area. The results also showed a higher ferrous iron concentration, a lower redox potential, and a higher (neutral) pH in the contaminated groundwater, suggesting that biodegradation of TEX(Toluene, Ethylbenzene, Xylene) is the major on-going process in the contaminated area. Groundwater in the contaminated area is anaerobic, and sulfate reduction is the dominant terminal electron accepting process in the area. The total attenuation rate was about 0.0017∼0.0224day$^{-1}$ and the estimated first-order degradation rate constant(λ) was 0.0008∼0.0106day$^{-1}$ . However, the reduction of TEX concentration in the groundwater was resulted from not only biodegradation but also dilution and reaeration through recharge of uncotaminated surface and groundwater. The natural attenuation was, therefore, found to be an effective, on-going remedial process at the site.

Attenuation Effects of Herbal Mixture Extract on Stress and Sleep Disturbance in Rats (구속 스트레스 및 수면장애를 유도한 흰쥐에서 허브 복합추출물에 의한 개선 효과)

  • Jung, An Na;Lee, Bo Kyung;Lee, Doo Yi;Lee, Ji In;Jung, Yi-Sook
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.45 no.3
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    • pp.313-320
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    • 2016
  • In the present study, we examined whether or not an herbal mixture extract (HME) has attenuation effects on immobilization stress and sleep disturbance in rats. Immobilization stress was induced by restricting movement using a constraint box for 2 h, and sleep disturbance was induced by exposure to 300 lx of constant light for 24 h and injection of caffeine (1 mg/kg, i.p.). Rats were orally treated with distilled water (vehicle) or HME for 3 weeks at different doses of 10, 30, and 100 mg/kg/d (HME I, II, and III, respectively). In the immobilization model, HME III treatment significantly decreased adrenal gland weight, whereas HME II and III treatment reduced plasma levels of cortisol. HME II and III also reduced the level of IL-6. In the sleep disturbance model, HME II and III meaningfully reduced the plasma level of cortisol, and the increased plasma level of melatonin. HME III significantly increased body weight. HME reduced immobilization stress and ameliorated disturbance in rats. These findings suggest that HME may have beneficial potential for attenuation of sleep disturbance and stress.

Highly efficient CMP surveying with ground-penetrating radar utilising real-time kinematic GPS (실시간 GPS를 이용한 고효율 GPR CMP 탐사)

  • Onishi Kyosuke;Yokota Toshiyuki;Maekawa Satoshi;Toshioka Tetsuma;Rokugawa Shuichi
    • Geophysics and Geophysical Exploration
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    • v.8 no.1
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    • pp.59-66
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    • 2005
  • The main purpose of this paper is to describe a highly efficient common mid-point (CMP) data acquisition method for ground-penetrating radar (GPR) surveying, which is intended to widen the application of GPR. The most important innovation to increase the efficiency of CMP data acquisition is continuous monitoring of the GPR antenna positions, using a real-time kinematic Global Positioning System (RTK-GPS). Survey time efficiency is improved because the automatic antenna locating system that we propose frees us from the most time-consuming process-deployment of the antenna at specified positions. Numerical experiments predicted that the data density and the CMP fold would be increased by the increased efficiency of data acquisition, which results in improved signal-to-noise ratios in the resulting data. A field experiment confirmed this hypothesis. The proposed method makes GPR surveys using CMP method more practical and popular. Furthermore, the method has the potential to supply detailed groundwater information. This is because we can convert the spatially dense dielectric constant distribution, obtained by using the CMP method we describe, into a dense physical value distribution that is closely related to such groundwater properties as water saturation.

The role of geophysics in understanding salinisation in Southwestern Queensland (호주 Queensland 남서부 지역의 염분작용 조사)

  • Wilkinson Kate;Chamberlain Tessa;Grundy Mike
    • Geophysics and Geophysical Exploration
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    • v.8 no.1
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    • pp.78-85
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    • 2005
  • This study, combining geophysical and environmental approaches, was undertaken to investigate the causes of secondary salinity in the Goondoola basin, in southwestern Queensland. Airborne radiometric, electromagnetic and ground electromagnetic datasets were acquired, along with data on soils and subsurface materials and groundwater. Relationships established between radiometric, elevation data, and measured material properties allowed us to generate predictive maps of surface materials and recharge potential. Greatest recharge to the groundwater is predicted to occur on the weathered bedrock rises surrounding the basin. Electromagnetic data (airborne, ground, and downhote), used in conjunction with soil and drillhole measurements, were used to quantify regolith salt store and to define the subsurface architecture. Conductivity measurements reflect soil salt distribution. However, deeper in the regolith, where the salt content is relatively constant, the AEM signal is influenced by changes in porosity or material type. This allowed the lateral distribution of bedrock weathering zones to be mapped. Salinisation in this area occurs because of local-andintermediate-scale processes, controlled strongly by regolith architecture. The present surface outbreak is the result of evaporative concentration above shallow saline groundwater, discharging at break of slope. The integration of surficial and subsurface datasets allowed the identification of similar landscape settings that are most at risk of developing salinity with groundwater rise. This information is now being used by local land managers to refine management choices that prevent excess recharge and further salt mobilisation.

Exploring Elementary Students' Positioning in a Context of Socio-scientific Issues (SSI) Education: Focus on an Action-oriented Climate Change Club Activity (과학 관련 사회적 문제 (SSI) 교육 맥락에서 초등학생의 위치짓기 양상 -실천 지향 기후변화 동아리 활동을 중심으로-)

  • Kim, Jong-Uk;Kim, Chan-Jong
    • Journal of The Korean Association For Science Education
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    • v.41 no.6
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    • pp.501-517
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    • 2021
  • In the present age, when the development of science and technology is leading the changes, this study supports the view that students should possess the literacy to participate democratically and critically in socio-scientific issues, and should be positioned as agentic and participatory citizens. Accordingly, we implemented a club activity that emphasize climate social action for elementary students, and explored how students were positioned in relation to climate change. In this study, position is defined as a complex cluster of rights and duties that students have in relation to climate change. The club activity was implemented throughout 46 sessions from March to July, 2019 for 11 sixth graders of 'H elementary School' in Seoul, and transcripts of video and interviews were analyzed by means of a constant comparison method. In the course of the activity consisting of three steps, the students exhibited different positioning and they are as follows: In the global warming modeling activity for Step 1, students were positioned as 'active learners', but at the same time, they showed a contradiction in being positioned as 'apprentice'. In the student-led research activities inherent to Step 2, they were positioned as 'scientists who design and conduct research' and 'bystanders' due to the controversial nature of SSI knowledge. As students participate in the social actions involved in Step 3, the position changed from 'elementary school students facing difficulty in making a change' to 'participatory citizens creating changes.' This study is significant because it shows students' potential to promote participatory and democratic citizenship through action-oriented SSI activities. In addition, pedagogical approaches were discussed dealing with the contradictions and limitations of positioning.