• 한국통신학회논문지
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• 제38A권8호
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• pp.650-655
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• 2013

광저장장치의 DC-억압을 위한 멀티모드 코딩 기법 중 Guided Scrambling (GS) 코딩기법이 널리 사용된다. 홀로그래픽 저장장치를 위한 DC-억압 GS코딩에서는 후보코드 선택기준으로 심볼의 균등한 분포 및 심볼간 천이의 최대화 기준이 고려되었다. 본 연구에서는 후보코드행렬의 digital sum value (DSV)의 $l_{\infty}$-norm을 최소화하는 minimum DSV (MDSV) 기준 GS코딩을 정수계획법 모형으로 수식화하고, 제안된 모형을 사용하여 MDSV 기준과 최대천이강도 기준이 적용된 GS코딩의 성능을 제어비트수, 행렬크기 및 스크램블링 다항식들의 조합에 대하여 평가한다.

• ETRI Journal
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• 제37권4호
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• pp.772-779
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• 2015

This paper presents a power-efficient hardware realization for a motion estimation technique that is based on the full-search block matching algorithm (FSBMA). The considered input is the quarter common intermediate format of digital video. The mean of absolute difference (MAD) is the distortion criteria employed for the block matching process. The conventional architecture considered for the hardware realization of FSBMA is that of the shift register-based 2-D systolic array. For this architecture, a conservative approximation technique is adapted to eliminate unnecessary MAD computations involved in the block matching process. Upon introducing the technique to the conventional architecture, the power and complexity of its implantation is reduced, while the accuracy of the motion vector extracted from the block matching process is preserved. The proposed architecture is verified for its functional specifications. A performance evaluation of the proposed architecture is carried out using parameters such as power, area, operating frequency, and efficiency.

• Restorative Dentistry and Endodontics
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• 제34권5호
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• pp.430-441
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• 2009

본 연구는 사람 치수세포 및 치주인대세포의 차이를 알아보고자 배양한 각각의 세포를 CDNA microarray assay를 통하여 유전자의 발현정도의 차이를 비교하였다. 그 결과를 바탕으로 각각의 세포에서 2배 이상의 유전자 발현의 차이를 보이는 유전자중 특징적인 3가지 유전자를 선택하여 RT-PCR로 검증한 결과 다음과 같은 결론을 얻었다; 1. Microarray assay 결과, 치주인대 세포에 비해 치수 세포에서 2배 이상 발현한 유전자 수는 총 51개가 나타났다. 2. RT-PCR의 결과, 치주인대세포에 비해 치수 세포에서 ITGA4, TGF-${\beta}2$ 등이 높게 나타났다. 3. Microarray assay결과, 치수 세포에서 비해 치주인대 세포에서 2배 이상 발현한 유전자 수는 총 19개가 나타났다. 4. RT-PCR의 결과, 치수 세포에 비해 치주인대세포에서 LUM, WISP1, MMP1 등이 높게 나타났다. 본 연구 결과로 치수세포에는 상아질 형성에 관여하는 특징적인 유전자가 치주인대세포에 비해 높게 발현되었으며, 치주인대세포에는 교원질 합성에 관여하는 특징적인 유전자가 치수세포에 비해 높게 발현되어, 치수세포와 치주인데 세포는 유전자 발현의 차이가 나타남을 알 수 있었다.

• 전기학회논문지
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• 제61권2호
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• pp.276-283
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• 2012

In this paper, a practical quasi-optimal DOA(direction of arrival) estimator is proposed in order to develop a one-axis gimbaled ultrasonic source tracker for mobile robot applications. With help of the gimbal structure, the ultrasonic moving source tracking problem can be simply reduced to the DOA estimation. The DOA estimation is known as one of the representative long-pending nonlinear filtering problems, but the conventional nonlinear filters might be restrictive in many actual situations because it cannot guarantee the reliable performance due to the use of nonlinear signal model. This motivates us to reformulate the DOA estimation problem in the linear robust state estimation setting. Based on the assumption that the received ultrasonic signals are noisy sinusoids satisfying linear prediction property, a linear uncertain measurement model is newly derived. To avoid the DOA estimation performance degradation caused by the stochastic parameter uncertainty contained in the linear measurement model, the recently developed NCRKF (non-conservative robust Kalman filter) scheme [1] is utilized. The proposed linear DOA estimator provides excellent DOA estimation performance and it is suitable for real-time implementation for its linear recursive filter structure. The effectiveness of the suggested DOA estimation scheme is demonstrated through simulations and experiments.

• 제어로봇시스템학회논문지
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• 제17권3호
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• pp.211-217
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• 2011

This paper proposes a quasi-optimal linear DOA (Direction-of-Arrival) estimator which is necessary for the development of a real-time robot auditory system tracking moving acoustic source. It is well known that the use of conventional nonlinear filtering schemes may result in the severe performance degradation of DOA estimation and not be preferable for real-time implementation. These are mainly due to the inherent nonlinearity of the acoustic signal model used for DOA estimation. This motivates us to consider a new uncertain linear acoustic signal model based on the linear prediction relation of a noisy sinusoid. Using the suggested measurement model, it is shown that the resultant DOA estimation problem is cast into the NCRKF (Non-Conservative Robust Kalman Filtering) problem [12]. NCRKF-based DOA estimator provides reliable DOA estimates of a fast moving acoustic source in spite of using the noise-corrupted measurement matrix in the filter recursion and, as well, it is suitable for real-time implementation because of its linear recursive filter structure. The computational efficiency and DOA estimation performance of the proposed method are evaluated through the computer simulations.

• Restorative Dentistry and Endodontics
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• 제27권5호
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• pp.543-551
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• 2002

Nitric oxide (NO) is a small molecule (mol. wt. 30 Da) and oxidative free radical. It is uncharged and can therefore diffuse freely within and between cells across membrane. Such characteristics make it a biologically important messenger in physiologic processes such as neurotransmission and the control of vascular tone. NO is also highly toxic and is known to acts as a mediator of cytotoxicity during host defense. NO is synthesized by nitric oxide synthase (NOS) through L-arginine/nitric oxide pathway which is a dioxygenation process. NO synthesis involves several participants, three co-substrates, five electrons, five co-factors and two prosthetic groups. Under normal condition, low levels of NO are synthesized by type I and III NOS for a short period of time and mediates many physiologic processes. Under condition of oxidant stress, high levels of NO are synthesized by type II NOS and inhibits a variety of metabolic processes and can also cause direct damage to DNA. Such interaction result in cytostasis, energy depletion and ultimately cell death. NO has the potential to interact with a variety of intercellular targets producing diverse array of metabolic effects. It is known that NO is involved in hemodynamic regulation, neurogenic inflammation, re-innervation, management of dentin hypersensitivity on teeth. Under basal condition of pulpal blood flow, NO provides constant vasodilator tone acting against sympathetic vasoconstriction. Substance P, a well known vasodilator, was reported to be mediated partly by NO, while calcitonin-gene related peptide has provided no evidence of its relation with NO. This review describes the roles of NO in dental pulp in addition to the known general roles of it.

• Nuclear Engineering and Technology
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• 제55권1호
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• pp.109-118
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• 2023

In this paper, the evaluation method of fluidelastic instability (FEI) of newly designed steam generator tubing in pressurized water reactor (PWR) nuclear power plants is discussed. To obtain the parameters for prediction of the critical velocity of FEI for steam generator tubes, experimental research is carried out, and the design parameters are determined. Using CFD numerical simulation, the tube array scale of the model experiment is determined, and the experimental device is designed. In this paper, 7 groups of experiments with void fractions of 0% (water), 10%, 20%, 50%, 75%, 85% and 95% were carried out. The critical damping ration, fundamental frequency and critical velocity of FEI of tubes in flowing water were measured. Through calculation, the total mass and instability constant of the immersed tube are obtained. The critical damping ration measured in the experiment mainly included two-phase damping and viscous damping, which changed with the change in void fraction from 1.56% to 4.34%. This value can be used in the steam generator design described in this paper and is conservative. By introducing the multiplier of frequency and square root of total mass per unit length, it is found that the difference between the experimental results and the calculated results is less than 1%, which proves the rationality and feasibility of the calculation method of frequency and total mass per unit length in engineering design. Through calculation, the instability constant is greater than 4 when the void fraction is less than 75%, less than 4 when the void fraction exceeds 75% and only 3.04 when the void fraction is 95%.

• BMB Reports
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• 제39권3호
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• pp.247-252
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• 2006

A rapid method for the detection of Hepatitis E Virus (HEV) was developed by utilizing nano-gold labeled oligonucleotide probes, silver stain enhancement and the microarray technique. The 5'-end -$NH_2$ modified oligonucleotide probes were immobilized on the surface of the chip base as the capture probe. The detection probe was made of the 3'-end -SH modified oligonucleotide probe and nano-gold colloid. The optimal concentrations of these two probes were determined. To test the detection sensitivity and specificity of this technique, a conservative fragment of the virus RNA was amplified by the RT-PCR/PCR one step amplification. The cDNA was hybridized with the capture probes and the detection probes on microarray. The detection signal was amplified by silver stain enhancement and could be identified by naked eyes. 100 fM of amplicon could be detected out on the microarray. As the results, preparation of nano-gold was improved and faster. Development time also was shortened to 2 min. Thus, considering high efficiency, low cost, good specificity and high sensitivity, this technique is alternative for the detection of HEV.

• 기본간호학회지
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• 제5권2호
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• pp.293-312
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• 1998

This study was designed to find the characteristics and patterns in subjectivity of an attitude on the induced abortion before marriage in women for a university student. Q-methodology was used as a research design and the research procedures were as follows. Q-sampling has been derived from the literature review and interview. Its credibility and validity were also tested by nursing and methodology professors. Total of 34 statements were selected. P-sampling has been drawn and 49 samples were selected. Based on 9 point scale, the slected respondents rated their operant definition on the induced abortion before marriage in women. The results of above procedures were analyzed by PCQ program. The attitude about the induced abortion before marriage in women were analyzed based on the typal array, extreme comments, and the demographic information of study subjects. The results revealed that there were three types of attitude about the induced abortion before marriage in women. The three types were named as follows ; 1) The first type, agree of conservative perspectives, was consisted of 15 subjects. They emphasized the sanctity of human life and the right of life that will never allow the killing fetus and prevention of induced abortion. 2) The second type, agree of liberal perspectives, was consisted of 10 subjects. They insisted the right to choice for women to control their body, so women have appropriate reason, they could choice induced abortion. 3) The third type, agree of compromise perspectives, was consisted of 7 subjects. They emphasized prevention of induced abortion but allowed under social permission. As a result, this study discovered three types of the attitude about the induced abortion before marriage in women. By identifying the nature of each of these types, this study can be useful to develop efficient strategies for preventing induced abortion.

• Applied Microscopy
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• 제37권2호
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• pp.93-102
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• 2007

분비백혈구단백분해효소억제제 (SLPI)와 여러 성장인자들은 상처 감염이나 박테리아 침입 시 일어나는 염증반응에 서로 관계가 있지만, 대식세포에서 LPS 자극시 SLPI와 VEGF, bFGF, PDGF 등과 같은 성장 인자들의 발현관계에 대해서는 아직까지 알려진 연구 결과가 없다. 따라서 본 연구는 대식세포 세포주로 알려진 RAW264.7 세포에 SLPI 발현의 적정농도인 LPS에 반응하는 SLPI 및 성장 인자들과 세포외부기질이 발현을 규명하고자 하였다. 역전사효소 중합반응(RT-PCR)과 면역학적 단백질 검출법(Western blotting)은 LPS 처리 후 SLPI와 몇몇 성장인자들 (VEGF, bFGF, PDGF)와 제1형 아교질 mRNA와 SLPI 단백질의 검출을 위해 수행하였다. RAW264.7 세포 주를 mL 당 100 ng의 LPS에 각각 30분, 60분, 90분, 24시간, 48시간동안 노출시켰다. RT-PCR 결과 SLPI mRNA는 시간이 지남에 따라 점점 발현 양이 증가하였고 VEGF와 PDGF mRNA는 초기에 높은 발현 양상을 보였다. 그러나 bFGF와 I형 아교질의 발현은 매우 미약하게 나타났다. SLPI 단백질 발현 역시 mRNA 수준과 마찬가지로 증가하는 양상을 보였는데, 배양액내의 SLPI 단백질양은 전체적으로 감소하는 경향을 보였다. 또한 광학현미경 관찰과 주사전자현미경 관찰결과, LPS가 RAW264.7 세포주의 형태학적인 변화를 일으킴을 확인하였다. 본 결과를 종합하면 SLPI 발현증가의 적정 농도라 생각되는 100ng의 LPS에 의해서 발현되는 VEGF나 PDGF는 SLPI의 발현에 관계가 있는 것으로 생각되지만 추후에 이들 인자들의 단백질이나 유전자 도입을 통하여 발현 관계를 명확히 확인해야 하는 추가실험이 진행되어야 할 것이다.하게 된다.토끼 면역항체를 선모충유충 조직항원에 반응시켰을 때 충체의 표피와 기저층 그리고 EIM 및 stichocyte의 ${\alpha}_0\;{\alpha}_1$ 과립에 황금입자가 표지되었다. 따라서 1일 동안 배설되는 분비배설항원은 선모충 유충의 표피와 stichocyte의 ${\alpha}_0\;{\alpha}_1$ 과립에서 유도되는 반면에 3일 동안 배설되는 분비배설항원은 표피와 stichocyte의 ${\alpha}_0$ 과립에서 유도되고, 선모충유충 감염후 1주, 4주에 실험쥐에서 형성되는 감염항체는 선모충의 표피와 기저층 그리고 EIM에서 분비되는 항원에 의하여 생성된다. 이상의 결과로 선모충의 분비배설항원과 감염항원은 선모충 유충의 표피와 EIM및 stichocyte의 ${\alpha}_0\;{\alpha}_1$ 과립에서 유도되며 이들은 45 kDa 단백을 포함하고 있는 것으로 생각된다.성하고 있는 세포들에는 세포질이 어두운 세포와 밝은 세포가 있었으며, 세포질내에는 전자밀도가 높은 분비과립이 관찰되었다. 전체적인 특징은 눈물샘분비세포 중 장액세포의 것과 비슷하였으나, 과립의 크기는 작았다. 분비관을 구성하는 세포들 사이에도 연접복합체가 매우 잘 발달되어 있었다. 샘포에서 사이관으로 이행되는 곳에서도 샘포세포와 사이관세포 사이에서도 연접복합체가 관찰되었다. 분비관세포의 분비과립 가운데는 중심부분에 전자밀도가 더 높은 중심을 가진 다른 모양의 과립이 관찰되기도 하였다. 의해 사망한 환자는 없었다. 결 론: 자궁경부암 환자에 항암화학요법과 동시에 외부 방사선조사와 고선량률의 강내조사를 시행한 결과 독성이 심하지 않고 국소제어율과 단기 생존율이 양호하여 안전하고 효율적인 치료방법으로 생각된다.