• Journal of the Korean Society of Costume
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• v.57 no.9
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• pp.136-148
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• 2007

The purpose of this study was to identify make-up benefits sought and attitudes according to the fashion lifestyle of silver women. Self-administered questionnaire was used for data collection, and subjects were silver women aged over 55 years. The results were as followed: 1. The factors of fashion lifestyle of silver women were clothing ostentation, leisure activity, interest in appearance, self-confidence, clothing conservation, and economics in clothing, and total variances was 70.99%. Silver women were clustered into high fashion-involvement group, medium fashion-involvement group, low fashion-involvement group, and fashion retard group according to fashion lifestyle. 2. High fashion-involvement group included more silver women with higher education and incomes, but fashion retard group included more with lower education and income. 3. High fashion-involvement group pursued self satisfaction, complement of defects, fashion trend following, politeness to others highly through make-up, and had higher concern and knowledge about make-up, and accepted plastic surgery or skin care positively. But fashion retard group pursued only a little and showed negative attitudes toward plastic surgery or skin care.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.47 no.1
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• pp.57-61
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• 2021

Immediate implant placement (IIP) in fresh extraction sockets exhibits similar survival and success rates to delayed implant placement in healed sockets. Several advantages of IIP involve shortened total treatment time, reduction of the number of invasive surgeries, and subsequent reduction of patient discomfort due to lack of additional surgeries. The major shortcomings in IIP, however, include the inability to obtain early bony support, presence of a gap between the extraction socket and fixture, and the inability to cover the fixture with soft tissue, leading to increased risk of infection and implant loss. When IIP is performed, atraumatic or minimally traumatic extractions, conservation of the septal bone in molars, minimal flap elevation or flapless surgery, bone grafting the gap between the fixture and the extraction socket, and coverage with soft tissue or a membrane must be considered.

• Genomics & Informatics
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• v.19 no.3
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• pp.32.1-32.10
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• 2021

Semisulcospira libertina, a species of freshwater snail, is widespread in East Asia. It is important as a food source. Additionally, it is a vector of clonorchiasis, paragonimiasis, metagonimiasis, and other parasites. Although S. libertina has ecological, commercial, and clinical importance, its whole-genome has not been reported yet. Here, we revealed the genome of S. libertina through de novo assembly. We assembled the whole-genome of S. libertina and determined its transcriptome for the first time using Illumina NovaSeq 6000 platform. According to the k-mer analysis, the genome size of S. libertina was estimated to be 3.04 Gb. Using RepeatMasker, a total of 53.68% of repeats were identified in the genome assembly. Genome data of S. libertina reported in this study will be useful for identification and conservation of S. libertina in East Asia.

• Radiation Oncology Journal
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• v.36 no.2
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• pp.139-146
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• 2018

Purpose: IBTR! 2.0 nomogram is web-based nomogram that predicts ipsilateral breast tumor recurrence (IBTR). We aimed to validate the IBTR! 2.0 using an external data set. Materials and Methods: The cohort consisted of 2,206 patients, who received breast conserving surgery and radiation therapy from 1992 to 2012 at our institution, where wide surgical excision is been routinely performed. Discrimination and calibration were used for assessing model performance. Patients with predicted 10-year IBTR risk based on an IBTR! 2.0 nomogram score of <3%, 3%-5%, 5%-10%, and >10% were assigned to groups 1, 2, 3, and 4, respectively. We also plotted calibration values to observe the actual IBTR rate against the nomogram-derived 10-year IBTR probabilities. Results: The median follow-up period was 73 months (range, 6 to 277 months). The area under the receiver operating characteristic curve was 0.607, showing poor accordance between the estimated and observed recurrence rate. Calibration plot confirmed that the IBTR! 2.0 nomogram predicted the 10-year IBTR risk higher than the observed IBTR rates in all groups. High discrepancies between nomogram IBTR predictions and observed IBTR rates were observed in overall risk groups. Compared with the original development dataset, our patients had fewer high grade tumors, less margin positivity, and less lymphovascular invasion, and more use of modern systemic therapies. Conclusions: IBTR! 2.0 nomogram seems to have the moderate discriminative ability with a tendency to over-estimating risk rate. Continued efforts are needed to ensure external applicability of published nomograms by validating the program using an external patient population.

• The Journal of the Convergence on Culture Technology
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• v.5 no.2
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• pp.123-138
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• 2019

The clinical institution of some dental hygiene students and the degree of practice and performance according to the practice contents are identified, so as to develop clinical practice guidelines and to improve the education of universities and practical institutions. From November 2016 to March 2017, the questionnaire was prepared by self-inclusion after explaining the purpose of research and how to prepare questionnaire to some dental hygiene students. This material has been analyzed using PASW Statistics 18.0. As for the clinical practice content items of basic care and infection control, the frequency of "execution" among practice methods was high, and the distribution rate was high in oral evil face radiation, preventive dentistry, prosthesis, periodontology, orthodontics, and oral internal medicine. The conservation department has conducted various practical methods such as "executing," "observing" and "preparing." Oral surgery showed similar distribution rates, such as "observation," "preparation," and "execution" in the "preparation and cooperation of the feet." In pediatric dentistry, "observation" was the most common practice, and among them, "observation," "preparation," and "execution" were performed in "preparation and cooperation for infantile development." In addition, students with more experience in clinical practice showed statistically significant differences in basic care, oral hygiene, preventative dentistry, conservation, dental dentistry, oral surgery, orthodontics, and oral internal medicine(p<0.05). Most clinical practice shows that it is more observable than performed.It is expected that the goal of clear clinical practice content should be set by grade or number of clinical practice experiences, as well as the practice method that can be performed by the trainees.

• Radiation Oncology Journal
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• v.22 no.2
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• pp.115-123
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• 2004

Purpose : This retrospective study was conducted to compare early preliminary results of breast conservation therapy (BCT) with mastectomy In early breast cancer. Materials and Methods : We evaluated 171 women with AJCC stage I and II breast cancer who had been treated at Kangnam St. Mary's Hospital from March 1989 to August 1996. Eighty-eight patients underwent mastectomy and 85 patients did conservative surgery with breast irradiation. in the BCT group, all patients received whole breast irradiation to a total dose of 45$\~$50 Gy/5$\~$6 wks, followed by a boost to the original tumor site at least 60 Gy. Chemotherapy was administered to 29 (34.1$\%$) patients in BCT and 40 (45.5$\%$) in mastectomy, with various sequencing of surgery and/or radiation. We compared survival rate, patterns of failure in each treatment group and the prognostic factors that had a significant effect on treatment failure. The median follow-up time was 63 months (19$\~$111 months). Log rank test was used to estimate the prognostic factors for treatment failure. Results : Overall survival, disease free survival, locoregional recurrence and distant metastasis rates were not significantly different between the two treatment groups. During the follow-up period, 11 patients (12.5$\%$)in the mastectomy group and 10 patients (11.8%$\%$ in the BCT group were failed. Six local recurrences occurred after mastectomy and 5 after BCT Five patients fatted at distant site in mastectomy and 4 in BCT. Of the local recurrence cases, five of 6 mastectomy patients and 3 of S BCT patients were alive with no evidence of disease after salvage surgery and/or chemoirradiation. Our results indicated that the major influence on survival was distant metastasis. Unfortunately, control of distant metastasisis was not frequently achieved. Even with salvage systemic therapy or radiotherapy, most of distant metastasis patients died or had uncontrolled disease in both treatment groups: only one of 4 BCT patients and none of mastectomy patients were alive without disease. There was no apparent difference in the incidence rate of contralateral breast cancer and non-breast 2$^{nd}$ primary tumor between the two treatment groups. Univariate Log-rank test identified the N stage and the involved axillary LN number as distinct prognostic factors that were highly predictive of treatment failure in both treatment groups. Additionally, marginal status in BCT and histologic nuclear grade In the mastectomy group were risk factors for treatment fallure (p < 0.05). Concousion : Although further careful follow-up is necessary to confirm the trends evident In this serles, it would appear that patterns of failure and survival rate following conservative surgery and radiotherapy in early breast cancer are similar to those following mastectomy. The great majority of patients with local recurrence had an exellent salvage rate in both treatment groups. Therefore, these preliminary short term results support BCT as an equally effective management for early breast cancer as an alternative to mastectomy.

• Journal of Biomedical Engineering Research
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• v.14 no.1
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• pp.51-62
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• 1993

An experimental study was performed for the preparation of living skin-equivalent by the using collagen gel contraction with human fibroblasts as neodermls and cultured human keratinocytes as neoderm is . The results were as follows ; 1) The rate of collagen gel contraction was dependent on the number of fibroblasts into the lattice and collagen contraction was progressed according to the increment of the number of the cells. 2) The rate of collagen gel contraction was progressed according to the decrement of the contraction of the collagen. 3) The rate of gel contraction was progressed according to the increment of serum concentration in the fixed concentration of the fibroblasts and collagen. 4) The lattice contraction was decreased according to the increment of the population doublings of the fibroblasts. 5) Macroscopically, the artificial dermis was gray white in color and tissue-like consistency and elas- ticity. 6) Microscopically, three dimensionally contracted artificial dermis showed more dense fibroblasts and its newly formed collagen fibrils in the matrix than one dimensionally contracted one. 7) Finally prepared skin-equivalent showed good attachment of living stratified keratinocytes to the dermal equivalent microscopically. It has been proposed that newly formed skin-equivalent is suitable for the graft of extensively and deeply burned patients. Shortening of the manufacturing period of skin-equivalent and development of conservation technique as a readily usable state are to be solved for our ongoing works.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.1
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• pp.315-320
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• 2014

Purpose: The purpose of this study was to investigate the recurrence pattern and characteristics of patients based on the 2013 St. Gallen surrogate molecular subtypes after breast-conserving surgery (BCS) in Chinese women. Methods: This retrospective analysis included 709 consecutive breast cancer patients undergoing BCS from 1999-2010 at our institution. Five different surrogate subtypes were created using combined expression of the estrogen receptor, progesterone receptor, and human epidermal growth factor receptor-2. Locoregional relapse-free survival (LRRFS), distant metastasis-free survival (DMFS), and disease-free survival (DFS) rates were calculated. Results: The 5-year LRRFS, DMFS, and DFS rates were 90.5%, 88.2%, and 81.5%, respectively. Multivariate analysis revealed that young age, node-positive disease, and HER2 enrichment were independent prognostic factors in LRRFS patients. There was also an independent prognostic role of lymph node-positive disease in DMFS and DFS patients. Patients with luminal A tumors had the most favorable prognosis, with LRRFS, DMFS, and DFS rates of 93.2%, 91.5%, and 87.4% at 5 years, respectively. Conversely, HER-2-enriched tumors exhibited the highest rate of locoregional recurrence (20.6%). Conclusion: Surrogate subtypes present with significant differences in RFS, DMFS, and LRRFS. Luminal A tumors have the best prognosis, whereas HER2-enriched tumors have the poorest.

• Journal of Korean society of Dental Hygiene
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• v.7 no.4
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• pp.365-379
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• 2007

The objective of the current study is to provide basic data necessary for the development of systematic program that is required for the systematic occupational work training of dental hygienists who newly employed at dental hospitals or clinics. The results of the surveys were listed as in below. The survey was conducted for 175 experienced dental hygienists who are in charge of occupational work training in 6 regions(Seoul, Kyunggi, Busan, Ulsan, Kwangju, Chungnam, Kyungnam) of the country where the occupational work training for new dental hygienists is systematically operated. 1. The recognition of experienced dental hygienists for the importance of occupational work training revealed that image training was the most importantly recognized by dental hygienists in Seoul Kyunggi regions(pE.01). In case of Busan region, periodontic training and conservative dentistry training were the most importantly recognized, and customer service training was mostly highly recognized in Ulsan region(pE.01). In case of Kwangjuregion, dental health insurance claim training was recognized as most important subject, and Patient consultation training was the most importantly recognized in Chungnam region. In case of Kyungnam region. Oral surgery was recognized as the most important training subject. 2. Regard on the importance of the range of occupational work training, the experienced dental hygienists with less than 2 years of experience were found to recognize the training of greeting and naming most importantly, the dental hygienists with 2~3 years of experience most importantly recognized oral surgery, and the dental hygienists with 4~5 year of experience were found to recognize conservative training most importantly. In case of dental hygienists having 6~9 year of experience recognized periodontic and conservation trainings as the most important subjects, and the dental hygienist having more than 10 years of experience were found to recognize conservative and image trainings mostly importantly.

• Journal of Korean Traditional Oncology
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• v.19 no.1
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• pp.43-51
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• 2014

This report is aimed to investigate the effect of Integrative Medicine Therapy (IMT) in treating breast cancer metastasized to several portion. A 55-year-old woman who was diagnosed breast cancer and treated by breast conservation surgery (BCS) IN 2002. (pT2M0N0), adjuvant chemotherapy and radiotherapy till Jan. in 2013. But cancer had metastasized to sacrum (2009), liver (2012) and ribs (2013). Finally cause of several side effects of Xeloda(neuralgia and vommiting), she gave up to be treated by Xeloda and started to receive IMT including Abnoba Viscum, Vitamin C therapy Xeloda again, Korean herbal medicine and pharmacopuncture from Jul. in 2013. The effect was evaluated with Positron Emission Tomography and Computed Tomography (PET-CT) and Abdomen Computed Tomography (CT). The metastatic tumor in liver was disappeared and cancers to ribs, their size decreased after 12 months and pain of sacrum maintained VAS 2 continually. These results suggest that IMT is a therapeutic method to treat metastatic tumor originated from breast cancer.