• Proceedings of the Korean Society for Bioinformatics Conference
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• 2003.10a
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• pp.26-51
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• 2003

Large scale protein interaction maps provide a new, global perspective with which to analyse protein function. PSIMAP, the Protein Structural Interactome Map, is a database of all the structurally observed interactions between superfamilies of protein domains with known three-dimensional structure in thePDB. PSIMAP incorporates both functional and evolutionary information into a single network. It makes it possible to age protein domains in terms of taxonomic diversity, interaction and function. One consequence of it is to predict the most important protein domain structure in evolution. We present a global analysis of PSIMAP using several distinct network measures relating to centrality, interactivity, fault-tolerance, and taxonomic diversity. We found the following results: ${\bullet}$ Centrality: we show that the center and barycenter of PSIMAP do not coincide, and that the superfamilies forming the barycenter relate to very general functions, while those constituting the center relate to enzymatic activity. ${\bullet}$ Interactivity: we identify the P-loop and immunoglobulin superfamilies as the most highly interactive. We successfully use connectivity and cluster index, which characterise the connectivity of a superfamily's neighbourhood, to discover superfamilies of complex I and II. This is particularly significant as the structure of complex I is not yet solved. ${\bullet}$ Taxonomic diversity: we found that highly interactive superfamilies are in general taxonomically very diverse and are thus amongst the oldest. This led to the prediction of the oldest and most important protein domain in evolution of lift. ${\bullet}$ Fault-tolerance: we found that the network is very robust as for the majority of superfamilies removal from the network will not break up the network. Overall, we can single out the P-loop containing nucleotide triphosphate hydrolases superfamily as it is the most highly connected and has the highest taxonomic diversity. In addition, this superfamily has the highest interaction rank, is the barycenter of the network (it has the shortest average path to every other superfamily in the network), and is an articulation vertex, whose removal will disconnect the network. More generally, we conclude that the graph-theoretic and taxonomic analysis of PSIMAP is an important step towards the understanding of protein function and could be an important tool for tracing the evolution of life at the molecular level.

• The Journal of the Korea Contents Association
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• v.15 no.9
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• pp.588-598
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• 2015

This study derives planning items and indicators that should be considered in order to activate public space in terms of the spatial characteristics of the public space was to analysis the importance in the public officials/academics and practitioners side. Derived in accordance with spatial planning topics characteristic of public space through previous research to them and after a detailed selection indicators in Christopher Alexander's Pattern Language was so lead through the FGI. Derived surface was subjected to the significance analysis AHP through the survey expert. For this study, the importance of the spatial characteristics of the public space are working professionals accessibility, publicity, connectivity, spatiality, amenity, placeness the order, public officials/academics accessibility, amenity, placeness, connectivity, spatiality, publicity the order. In addition, professionals working in the comprehensive analysis of the most important priority was to recognize the hierarchy of open space, public officials/academics appeared to have an open space on the street the most important. The results obtained in this study will be used as an index that can be used in planning and evaluation for consideration of the next active public space.

• Journal of the Korean Association of Geographic Information Studies
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• v.25 no.2
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• pp.59-71
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• 2022

This study considered regional differences in the university-industry collaboration of Korean universities and performed cluster analysis to identify the spatial range with high university-industry collaboration connectivity. By university establishment type, it was found that the university-industry collaboration capacity of the major national university was superior overall, especially in the technology transfer & commercialization sector and the infrastructure sector, compared to private universities and general national universities. The spatial pattern of university-industry collaboration capacity showed relatively clear differences by city and province. In terms of university-industry collaboration capacity by sector, it was confirmed that the regional gap was not large in the talent training sector and the infrastructure sector, but the regional gap was relatively large in the technology transfer & commercialization sector and the start-up sector. As a result of the cluster analysis to identify a spatial range with high connectivity in terms of similarity and spatial proximity of university-industry collaboration patterns, it is divided into 15 clusters. It is found that most of major national universities are included in one of 15 clusters where all sectors of university-industry collaboration are strong. Therefore, as a policy measure to achieve regional innovative growth through enhancing the effectiveness of university-industry collaboration, we propose the establishment of a hub & spoke network-type collaboration system in which a major national university acts as a hub and nearby local universities play a spoke role.

• Korean Journal of Environment and Ecology
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• v.28 no.3
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• pp.365-373
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• 2014

This study is to analyze the physical environment and conduct spatial data for bicycle road system in changwon. Index for evaluation index was developed based on literatures. Then the level of importance and weight have been modified through experts review. Finally, index with eight categories such as greenness(40% over), bicycle road connectivity(1.8, 9.8%), road type bike(bicycle lane, 24.4%), pave type(asphalt 72.5%), illegal parking(none, 93.9%), bike road surface visibility(exist, 46.8%), vehicle speed limits(30km, under), vehicle traffic(500/hr under, 44.3%) have been applied to empirical investigation. Collected data has been hierarchically classification by ArcGIS Program. The Highest grades(score 31-35, level 1) occupied 35% of target destination. High level of greenness and load type has contributed to high score. In addition, average level of greenness of those destination was 35% and higher, which provide high degree of security and freshness for bicycle riding. Meanwhile, lowest level(level 5, which earned 15 point or less) occupied 24.5%. illegal parking, low level of greenness, and no surface sign caused low score.

• Journal of Wetlands Research
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• v.18 no.4
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• pp.378-385
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• 2016

This study aims to suggest the framework of functional assessment on lotic area based on HGM(Hydrogeomorphic) approach targeting Wetland Protected Areas which are in the type of river channel, and to set up the fundamental data as a reference wetland. A total of 10 factors in terms of hydrology, biogeochemistry, plant habitat and animal habitat was analyzed based on the original approach of HGM and each Functional Capacity Index(FCI) of those factors was calculated. As the result of the modified FCI analysis, Damyang riverine wetland which is with artificial river bank had high values in the variables of area ratio of actual vegetation in the foreland, the number of plant per area and the area ratio of Salix spp., and those values were highly reflected on the factors of Nutrient Cycling(947,668.00), Species Richness and Maintain Characteristic Plant Communites(6.39) and Maintain Spatial Structure of Habitat(11.00). The Hanbando wetland which is keeping the natural bank had higher values in the variables of structural scale and species diversity, and the those values were highly reflected on the factors of Energy Dissipation(17,805.16), Subsurface Storage of Water(0.54), Removal of Imported Elements and Compounds(103,052.73), Maintain Characteristic Detrital Biomass(2.31), Maintenance of Interspersion and Connectivity (6.50), Species Diversity of Benthic macro-invertebrates(1.60) and Species Diversity of Vertebrate & Species Number of Other Animals(2.52/ 151.50), compared to the Damyang Riverine Wetland.

• Journal of Korea Port Economic Association
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• v.38 no.3
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• pp.1-13
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• 2022

The Busan-Ulsan-Gyeongsangmando(BuUlGyeong) megacity aims to grow into the second metropolitan area by strengthening the growth and connectivity of the southeast region in Korea. In order to analyze the linkage between port logistics and regional economic development, this study focused on the economic community of BuUlGyeong. The findings are as follows. First, it was found that vessel entry and departure had a positive (+) significant effect on cargo volume. Second, the cargo volume was found to have a preemptive effect on the vessel entry and exit ports and the composite index. Third, the composite Index was found to have a significant positive (+) effect on cargo volume. From the results of the variance decomposition, it can be confirmed that the composite index has a weak impact on ship entry/exit and cargo volume. Based on the above findings, some policy implications are derived. First, regional governments in BuUlGyeong should provide incentives to revitalize the maritime economy such as the expansion of maritime port infrastructure and encouraging investment. Second, since an increase in cargo transport volume at major national ports linked to the BuUlGyeong region has a positive (+) effect on economy. Therefore it is necessary to expand actively port marketing and regular service for the country and ports. Third, investments should be made continuously to expand the marine port infrastructure such as the expansion of facilities so that global shipping companies can continue to call megacities in BuUlGyeong ports for super-large ships and cruises.

• Journal of The Korea Institute of Healthcare Architecture
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• v.21 no.2
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• pp.7-15
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• 2015

Purpose: The purpose of this study is analyze linkage and spatial and structural characteristics of outpatient department and diagnosis/treatment area of geriatric hospitals based on quantitative analysis, according to function and corridor types. Methods: To examine structural characteristics and correlation of outpatient department and diagnosis/treatment area of six geriatric hospitals according to the corridor type, were systemized according to the function and corridor type and made into a j-graph, and an index was created by using space syntax to understand spatial characteristics. Results: 1) Different functional spaces are connected by a corridor, which, therefore, can be an axis of the connectivity and linkage of functional spaces and an important element in a clear hierarchy. 2) Treatment areas were disconnected from different functional spaces and, therefore, the accessibility was low. Many hospitals had an arrangement plan for treatment and diagnosis areas, and recent hospitals have segmented treatment areas within the rehabilitation space, which resulted in deeper space. 3) In terms of the level of integration, more integrated reception area meant shallower spatial depth, and deeper space for treatment and diagnosis areas. Implications: Spatial relation of outpatient department of geriatric hospitals was analyzed based on characteristics of the elderly.

• Korean Journal of Acupuncture
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• v.29 no.3
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• pp.431-440
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• 2012

Objectives : Recently, network science is very popular topic in various scientific fields and many studies have reported that it gives meaningful results on studying characteristics of a complex system. In this study, based on network theory, we made acupoints network using data of combined acupoints which appeared at "Beijiqianjinyaofang". We focused to find out the distinctive roles of remote and local combinations on the network. Furthermore, we aimed to identify the possibility of numerical and quantitative application to acupuncture researches. Methods : Based on examples of combined acupoints in "Beijiqianjinyaofang", the network consisted of 291 nodes and 2,431 links. The spatial distances between combined acupoints were calculated by the human dummy model. We removed the links step by step for the three cases - remote, local, and random cases, and observed the characteristic changes by calculating path lengths, similarity indices, and clustering coefficients. Also cluster analysis was carried out. Results : The network had a small number of remote links, and a large number of local links. These two links had the distinct characteristics. Whereas the local links formed a cluster of nearby nodes, remote links played a role to increase the correlation between the clusters. Conclusions : These results suggest that acupoints network increases the connectivity between the distal part and the trunk of human body, and enables various combinations of the acupoints. This finding conclusively showed that mechanism of combined acupoints could be interpreted meaningfully by applying network theory in acupuncture researches.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.15 no.4
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• pp.117-130
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• 2007

Incheon International Airport has handled 3,054,485 transfer passengers (11.9% transfer rate) and 950,441 transfer cargo(44.2% transfer rate)recorded in 2005. Comparing to 30-40% transfer passenger rate which are competition hub airports in northeast Asia, transfer passenger rate of Incheon International Airport is lower. Above all, We think that Minimum Connecting Time(MCT) which is relating factors with transfer rate need to be monitored to make up for the weak points in the current Incheon internationalairport system. Minimum Connecting Time is defined the legally minimum time necessary to change planes at a given airport. and Transfers represent 35% of the total passenger volume at Vienna International Airport in Europe, which underscores our function as a major international hub. Vienna is rated priority in reservation systems because of our excellent minimum connecting time, and that increases the sale of tickets through our airport. In 2004 the total number of transfer passengers rose 18% to 5,089,624. Short routes, a one roof concept and an outstanding logistics system make Vienna an ideal airport for transfers. This transfer-friendly one roof concept will also form the basis for the new VlE-Skylink Terminal. In case of Japan, Star Alliance has also implemented its so called "Move under one roof"concept at the new Centrair airport. All member carriers are located in the same part of the termina1, sharing check-in counters and ticketing facilities. Star Alliance member carriers can now offer customersa reduced average minimum connecting time of one hour, for transfers between international and domestic. The research purpose of the Study on the Enhancement for Minimum Connecting Time of Incheon International Airport is to increase transfer rate of passenger and cargo of Incheon International Airport at Northeast Asia through this paper.

• Journal of Ecology and Environment
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• v.39 no.1
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• pp.43-49
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• 2016

Fishways are constructed to provide longitudinal connectivity of streams or rivers where their flow has been altered by in-stream structures such as dams or weirs. Nature-like fishways have an additional function of providing fish habitats. In the study, we estimated the role of a nature-like fishway (length: 700 m, slope: 1/100) for fish habitat by using two dominant species in the Sangju Weir, Nakdong River, to calculate the optimal ecological flow rate using Physical HABitat SIMulation (PHABSIM). To identify the dominant species that used the fishway, we conducted trap monitoring from August to November 2012 at the fishway exit. The dominant species were Zacco platypus and Opsariichthys uncirostric amurensis with a relative abundance of 62.1% and 35.9%, respectively. Optimal habitat suitability indices (HSIs) for Z. platypus and O. u. amurensis were calculated as 0.6-0.8 m/s (water velocity) and 0.2-0.4 m (water depth), and 0.5-0.7 m/s (water velocity) and 0.1-0.3 m (water depth), respectively. The optimal ecological flow rates (OEFs) for Z. platypus and O. u. amurensis were 1.6 and 1.7 cubic meter per second (CMS), respectively. The results of the study can be used in a management plan to increase the habitat function of nature-like fishways in the Sangju Weir. This methodology can be utilized as an appropriate tool that can determine the habitat function of all nature-like fishways.