• Title/Summary/Keyword: Confocal Raman spectroscopy

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Reliability Improvement of Automatic Basal Cell Carcinoma Classifier with an Ambiguous Pattern Class (모호한 패턴 클래스 도입을 통한 기저 세포암 분류기의 신뢰도 향상)

  • Park, Aa-Ron;Baek, Seong-Joon;Jung, In-Wook;Song, Min-Gyu;Na, Seung-Yu
    • Journal of the Institute of Electronics Engineers of Korea CI
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    • v.44 no.1
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    • pp.64-70
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    • 2007
  • Raman spectroscopy is known to have strong potential for providing noninvasive dermatological diagnosis of skin cancer. According to the previous work, various well known methods including maximum a posteriori probability (MAP) and multilayer perceptron networks (MLP) showed competitive results. Since even the small errors often leads to a fatal result, we investigated the method that reduces classification error perfectly by screening out some ambiguous patterns. Those ambiguous patterns can be examined by routine biopsy. We incorporated an ambiguous pattern class in MAP, linear classifier using minimum squared error (MSE), MLP and reduced coulomb energy networks (RCE). The experiments involving 216 confocal Raman spectra showed that every methods could perfectly classify BCC by screening out some ambiguous patterns. The best results were obtained with MSE. According to the experimental results, MSE gives perfect classification by screening out 8.8% of test patterns.

Installation and Operation of a Double-Sided Laser Heating System for the Synthesis of Novel Materials Under Extreme Conditions (극한 조건하에서 신물질 합성을 위한 양쪽 가열 레이저 가열 시스템 설치 및 운영)

  • Ko, Young-Ho;Oh, Kyoung Hun;Kim, Kwang Joo
    • New Physics: Sae Mulli
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    • v.69 no.10
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    • pp.1107-1114
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    • 2019
  • Producing extremely stable high temperature and pressure condition is crucial in order to synthesize novel materials with various functions and to investigate their static and dynamic properties. Already a high pressure in the Mbar range, which is necessary to make novel materials, can be acquired by using a Diamond Anvil Cell (DAC), In this study, a laser-heating system combined with the DAC was designed and installed using two 1064-nm, 100-W fiber lasers on different sides of the DAC to heat the sample and three spectrometers to measure the temperature, pressure, and Raman spectra. A stainless-steel gasket, which is generally used as a sample chamber in high-pressure experiments, was heated to make a thermal radiation source, and the temperature of the heated gasket was obtained by measuring the spectrum of the radiation. By applying this technique, we were able to make various materials and to investigate their physical properties under extreme conditions.