Background: Vitamin D has been suggested as one of the critical factors for female reproductive health with protective activities against different cancers but there are conflicting facts regarding its role on breast cancer without any clear data on premenopausal cases. This study aimed to evaluate the role of vitamin D from dietary sources and sunlight exposure on the incidence of premenopausal breast cancer. Materials and Methods: We conducted a case control study on 60 newly diagnosed premenopausal breast cancer patients and 116 normal women who lived in Sabzevar and surrounding villages in Razavi, Khorasan, a rural and conservative area of Iran. Results: The mean concentrations of 25-OH vitamin D in cases and controls were $15.2{\pm}8.15$ vs $15.5{\pm}7/45ng/ml$, both well below normal values elsewhere. In fact 50% of analyzed individuals showed very severe or severe vitamin D deficiency and the rest (25%) were detected in suboptimal levels. Although the lack of vitamin D and calcium supplementation increased slightly the risk of premenopausal breast cancer (p=0.009, OR=1.115, CI 95%=1.049-1.187), higher prevalence of weekly egg consumption (86.66% vs 96.55%, p=0.023, OR=0.232, CI 95% 0.065-0.806) showed a slight protective role. The last but the most important risk factor was lack of sunlight exposure because the breast cancer patients had total body coverage from sun (p=0.007, OR=10.131, CI 98% 0.314-78.102). Conclusion: This study pointed out the role of vitamin D and other possible risk factors on the development and growth of breast tumors in this special geographical region. Although this study has revealed the interactions between hormonal and environmental factors in this province of Iran, understanding the deficiency pattern and its contribution to other lifestyle factors elsewhere is also necessary.
As an empirical study on the psychological side effects of using Social Networking Services (SNS), this study aims to identify the reality of negative emotion of using SNS and to predict its consequences. To this end, a measurement tool was developed through literature review, in-depth interview with users and expert review to induce negative emotional factors that can arise while using SNS. An exploratory factor analysis was performed for a total of 24 measurement items, which then were divided into the following 6 factors: 'concern over privacy,' 'burden from undesired connection,' 'relative deprivation,' 'a sense of alienation,' 'concern over reputation' and 'negative feeling about simple relationship.' Also, the relationship between the 6 negative emotional factors and psychological dissonance was analyzed. The results indicate that all the factors, except relative deprivation and a sense of alienation, affect psychological dissonance. It was also found that psychological dissonance, which implies a conflicting condition from using SNS, significantly affects the behavior that possibly reduces and limits the use of SNS. In other words, the users who have experienced psychological dissonance respond passively by avoiding the use of SNS to resolve the dissonance. The results of this study provide the base for explaining the psychological side effects of using SNS, which have been understood at a phenomenal level, such as 'Facebook depression' or 'SNS stress.' In addition, this study is of significance as it helps understand the psychological mechanism by identifying the relationship between negative emotion and use behavior with the theory of cognitive dissonance.
Purpose - Although the importance and necessity of "sustainable supply chain management (SCM)" is emphasized, it is often not realized due to conflicting results, the long time required, and large-scale changes brought about by sustainability. This study used the innovation resistance model to confirm the influence of sustainable SCM innovation resistance factors and dynamic capabilities on adoption intentions. This approach made it possible to understand the factors that hinder adoption of sustainability practices and to identify the relationships among influencing factors. It should also help to establish effective policies or strategies. Design/methodology - Through a literature review, the characteristics of sustainable SCM were classified into relative advantage, compatibility, perceived risk, and complexity. The effects of these innovation characteristics on innovation resistance in sustainable SCM and the effects of innovation resistance on adoption intentions were confirmed. In addition, the effects of SCM capabilities on innovation resistance and adoption intentions were analyzed, and the mediating effect of innovation resistance was analyzed. Findings - Compatibility, perceived risk, and flexibility had significant effects on innovation resistance. In turn, innovation resistance had a significant effect on adoption intention, and flexibility had a significant effect on intention to adopt. A partial mediating effect of resistance to innovation was confirmed. Originality/value - Although many previous studies have acknowledged trade-offs with sustainability, most sustainable SCM studies dealt with the correlations among positive drivers of adoption, practices, and performance. This study confirmed the process of accepting sustainable SCM innovation in a single model and is expected to serve as a cornerstone for future sustainable SCM adoption studies. In addition, our findings should help establish effective policies or strategies to activate SSCM adoption by identifying the factors that hinder the adoption of sustainable SCM.
Objectives: Professional firefighters face various health hazards and are required to maintain both physical and mental fitness to effectively mitigate crises and respond to emergencies. Moreover, the long working hours and shift work of this profession impact sleep quality. This study investigated the quality of sleep and its associated factors among firefighters in Bangkok, Thailand. Methods: This was a cross-sectional study of firefighters affiliated with the Bangkok Fire and Rescue Department, Bangkok Metropolitan Administration, Thailand between January 2023 and March 2023. A cluster random sampling technique was utilized to distribute 600 questionnaires to firefighters in 15 fire stations. The questionnaire addressed demographic, work-related, and environmental factors. Sleep quality was assessed using the Thai version of the Pittsburgh Sleep Quality Index (PSQI). Data analysis involved both descriptive and inferential statistics. Bivariate and multiple logistic regressions were performed. Results: The response rate was 78.7% (n=472), and 44.1% of the firefighters reported poor sleep quality (PSQI score >5). Sleep quality was statistically associated with conflicting family relationships (odds ratio [OR], 1.8; 95% confidence interval [CI], 1.1 to 2.9), additional part-time jobs (daytime, OR, 2.4; 95% CI, 1.3 to 4.4; or nighttime, OR, 4.3; 95% CI, 1.1 to 16.7), noisy sleeping areas (OR, 1.7; 95% CI, 1.1 to 2.8), and the availability of adequate bedding (OR, 3.0; 95% CI, 1.8 to 4.9). Conclusions: Poor sleep quality among firefighters was associated with various personal, work-related, and environmental factors. Organizations should promote policies that improve sleep quality through good sleep hygiene practices and facilities.
Kim, Sung-Ho;Son, Sang-Yong;Park, Young-Suk;Ahn, Sang-Hoon;Park, Do Joong;Kim, Hyung-Ho
Journal of Gastric Cancer
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제15권3호
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pp.167-175
/
2015
Purpose: Although several studies report risk factors for anastomotic leakage after gastrectomy for gastric cancer, they have yielded conflicting results. The present retrospective cohort study was performed to identify risk factors that are consistently associated with anastomotic leakage after gastrectomy for stomach cancer. Materials and Methods: All consecutive patients who underwent gastrectomy at a single gastric surgical unit between May 2003 and December 2012 were identified retrospectively. The associations between anastomotic leakage and 23 variables related to patient history, diagnosis, and surgery were assessed and analyzed with logistic regression. Results: In total, 3,827 patients were included. The rate of anastomotic leakage was 1.88% (72/3,827). Multiple regression analysis showed that male sex (P=0.001), preoperative/intraoperative transfusion (P<0.001), presence of cardiovascular disease (P=0.023), and tumor location (P<0.001) were predictive of anastomotic leakage. Patients with and without leakage did not differ significantly in terms of their 5-year survival: 97.6 vs. 109.5 months (P=0.076). Conclusions: Male sex, cardiovascular disease, perioperative transfusion, and tumor location in the upper third of the stomach were associated with an increased risk of anastomotic leakage. Although several studies have reported that an anastomotic complication has a negative impact on long-term survival, this association was not observed in the present study.
Tucer, Bulent;Ekici, Mehmet Ali;Demirel, Serkan;Basarslan, Seyit Kagan;Koc, Rahmi Kemal;Guclu, Bulent
Journal of Korean Neurosurgical Society
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제52권1호
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pp.42-47
/
2012
Objective : The aim of this prospective study was to demonstrate the influence of some factors on the prognosis of microvascular decompression in 37 patients with trigeminal neuralgia. Methods : The results of microvascular decompression (MVD) in 37 patients with trigeminal neuralgia were evaluated at 6 months after surgery and were compared with clinical and operative findings. Results : The sex of the patient, the patient's age at surgery, the side of the pain, and the duration of symptoms before surgery did not play any significant roles in prognosis. Also, the visual analogue scale (VAS) of the patient, the duration of each pain attack, and the frequency of pain over 24 hours did not play any significant roles in prognosis. In addition, intraoperative detection of the type of conflicting vessel, the degree of severity of conflict, and the location of the conflict around the circumference of the root did not play any roles in prognosis. The only factors affecting the prognosis in MVD surgery were intraoperative detection of the site of the conflict along the root and neuroradiological compression signs on preoperative magnetic resonance imaging (MRI)/magnetic resonance angiography (MRA). Conclusion : These findings demonstrated that if neurovascular compression is seen on preoperative MRI/MRA and/or compression is found intraoperative at the root entry zone, then the patient will most likely benefit from MVD surgery.
Background: In this study, we tried to comprehensively explore clinical dental hygienist's experience of a prevention-based incremental oral health care program, which was pilot-operated by dental clinics, define prevention-based incremental oral health care as experienced in the field, and identify factors to be considered. Methods: This study conducted a focus group interview with five dental hygienists who participated in an ongoing oral management pilot project in 2016. The interview was conducted by a researcher, and the co-research team attended as progress assistants and recorded characteristics of the participants, main dictations, and non-verbal characteristics. All interviews were recorded and underwent thematic analysis to examine the questions of the study as the main axis. Results: As a result of the study, 65 meaningful statements were extracted by code, integrated into 24 sub-categories, and structured into 11 categories. Finally, four keywords were drawn: characteristics, facilitating factors, conflicting factors, and improvement measures for prevention-based incremental oral health care. Regarding prevention-based incremental oral health care in dental clinics, dental hygienists were highly aware of the physical and mental burdens of personalized treatment and education for each individual. They were responsible for the patient and for facilitating changes in the behavior of the client, leading to professional satisfaction. The dental team's cooperation and supportive attitude were found essential to continue oral health care in the dental clinic. Conclusion: Through dental team-based treatment philosophy sharing and collaboration, it is possible to provide prevention-based incremental oral health care in dental clinics. In future, it is necessary to develop a system for establishing a sustainable preventative management system for public health promotion.
It is well known that acupuncture is effective for treatment of gastric disease in human. For years, we have been utilizing a electro-acupuncture(EA) in attempt to manage gastric symptoms. However, the data on clinical effectiveness is conflicting and the action of acupoints is unclear. The purpose of this study was to investigate the effects of manual and electro acupuncture(EA) at acupoints of ST 36 and GB 34 on the serum gastrin level by radioimmunoassay in rats. All of acupuncture treatment was applied to the acupoints for 30 min during 3 days. Manual acupuncture with both acupoints resulted in increased gastrin serum level when compare to control group treated with only anesthesia. Either high (100 Hz) and low (2 Hz) frequency EA at ST 36 decreased gastrin serum level compared with control group, but EA at GB 34 conversely increased. In EA with device was designed stimulating only acupoint(New EA), either low frequency on ST 36 and high frequency on GB 34 unusually increased gastrin serum level compared to control group. The results of this experiment suggest that many factors, such as the selection of acupoints, the manipulation and the specification of acupuncture device, are capable of affecting acupuncture effects.
The purpose of this thesis is to provide an appropriate trade-off information for the conflicting interests caused by the various factors between building owner and contractor during selecting the contractor and performing the construction work, in which the construction was contracted by open bidding from the government or private organizations. In order to propose the legitimate evidence, the differences between the domestic contract sheet of drawing change and the process of drawing change and those of the foreign countries were compared and analysed The number of construction ordered in Youngdong area in 2001 whose construction expenses are more than 100,000,000 won is 218 items and 147,005,000,000 won in total cost Among them, the number of 218 items whose total cost amounts to 16,705,000,000 (11.36$\%$) is in case of increase of construction expenses due to the drawing changes, and the number of 48 items whose tool cost amounts to 2,009,000,000 won (1.37$\%$) is the case of decrease. In conclusions, the contractor could have more benefits than the building owner in case they submit the detailed estimate sheet without eliminating the increasing expenses of construction. It is shown that the building owner's loss is increasing whenever the labor cost is higher material cost Therefore, this thesis proposes a proper standards for the harmonious compromise between the contractor and the building owner for the problems caused by the drawing changes when the contract agreement is occurred.
To ensure that equipment outages do not directly impact the reliability of the ISO-controlled grid, market participants request permission and receive approval for planned outages from the independent system operator (ISO) in competitive electricity markets. In the face of major generation outages, the ISO will make a critical decision as regards the scheduling of the essential maintenance for myriads of generating units over a fixed planning horizon in accordance with security and adequacy assessments. Mainly, we are concerned with a fundamental framework for ISO's maintenance coordination in order to determine precedence of conflicting outages. Simulated annealing, a powerful, general-purpose optimization methodology suitable for real combinatorial search problems, is used. Generally, the ISO will put forward its best effort to adjust individual generator maintenance schedules according to the time preferences of each power generator (GENCO) by taking advantage of several factors such as installed capacity and relative weightings assigned to the GENCOs. Thus, computer testing on a four-GENCO model is conducted to demonstrate the effectiveness of the proposed method and the applicability of the solution scheme to large-scale maintenance scheduling coordination problems.
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