• Title/Summary/Keyword: Confidence-Flow

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Development of Vehicle Arrival Time Prediction Algorithm Based on a Demand Volume (교통수요 기반의 도착예정시간 산출 알고리즘 개발)

  • Kim, Ji-Hong;Lee, Gyeong-Sun;Kim, Yeong-Ho;Lee, Seong-Mo
    • Journal of Korean Society of Transportation
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    • v.23 no.2
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    • pp.107-116
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    • 2005
  • The information on travel time in providing the information of traffic to drivers is one of the most important data to control a traffic congestion efficiently. Especially, this information is the major element of route choice of drivers, and based on the premise that it has the high degree of confidence in real situation. This study developed a vehicle arrival time prediction algorithm called as "VAT-DV" for 6 corridors in total 6.1Km of "Nam-san area trffic information system" in order to give an information of congestion to drivers using VMS, ARS, and WEB. The spatial scope of this study is 2.5km~3km sections of each corridor, but there are various situations of traffic flow in a short period because they have signalized intersections in a departure point and an arrival point of each corridor, so they have almost characteristics of interrupted and uninterrupted traffic flow. The algorithm uses the information on a demand volume and a queue length. The demand volume is estimated from density of each points based on the Greenburg model, and the queue length is from the density and speed of each point. In order to settle the variation of the unit time, the result of this algorithm is strategically regulated by importing the AVI(Automatic Vehicle Identification), one of the number plate matching methods. In this study, the AVI travel time information is composed by Hybrid Model in order to use it as the basic parameter to make one travel time in a day using ILD to classify the characteristics of the traffic flow along the queue length. According to the result of this study, in congestion situation, this algorithm has about more than 84% degree of accuracy. Specially, the result of providing the information of "Nam-san area traffic information system" shows that 72.6% of drivers are available.

Respiratory air flow transducer calibration technique for forced vital capacity test (노력성 폐활량검사시 호흡기류센서의 보정기법)

  • Cha, Eun-Jong;Lee, In-Kwang;Jang, Jong-Chan;Kim, Seong-Sik;Lee, Su-Ok;Jung, Jae-Kwan;Park, Kyung-Soon;Kim, Kyung-Ah
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.10 no.5
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    • pp.1082-1090
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    • 2009
  • Peak expiratory flow rate(PEF) is a very important diagnostic parameter obtained from the forced vital capacity(FVC) test. The expiratory flow rate increases during the short initial time period and may cause measurement error in PEF particularly due to non-ideal dynamic characteristic of the transducer. The present study evaluated the initial rise slope($S_r$) on the flow rate signal to compensate the transducer output data. The 26 standard signals recommended by the American Thoracic Society(ATS) were generated and flown through the velocity-type respiratory air flow transducer with simultaneously acquiring the transducer output signal. Most PEF and the corresponding output($N_{PEF}$) were well fitted into a quadratic equation with a high enough correlation coefficient of 0.9997. But only two(ATS#2 and 26) signals resulted significant deviation of $N_{PEF}$ with relative errors>10%. The relationship between the relative error in $N_{PEF}$ and $S_r$ was found to be linear, based on which $N_{PEF}$ data were compensated. As a result, the 99% confidence interval of PEF error was turned out to be approximately 2.5%, which was less than a quarter of the upper limit of 10% recommended by ATS. Therefore, the present compensation technique was proved to be very accurate, complying the international standards of ATS, which would be useful to calibrate respiratory air flow transducers.

Ictal single-photon emission computed tomography with slow dye injection for determining primary epileptic foci in infantile spasms (영아연축에서 추적자의 느린 점적주사를 이용한 발작기 SPECT)

  • Hur, Yun Jung;Lee, Joon Soo;Kang, Hoon Chul;Park, Hye Jung;Yun, Mi Jin;Kim, Heung Dong
    • Clinical and Experimental Pediatrics
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    • v.52 no.7
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    • pp.804-810
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    • 2009
  • Purpose : We investigated whether ictal single-photon emission computed tomography (SPECT) with prolonged injection of technetium-99m (99mTc) ethyl cysteinate dimer during repeated spasms can localize the epileptogenic foci in children with infantile spasms. Methods : Fourteen children with infantile spasms (11 boys, 3 girls; mean age, $2.2{\pm}1.3$ years) were examined. When a cluster of spasms was detected during video electroencephalography (EEG) monitoring, $^{99m}Tc$ ethyl cysteinate dimer was slowly and continuously injected for 2 minutes to determine the presence of ictal SPECT. For 7 children, the ictal and interictal SPECT images were visually analyzed, while for the remaining 7 children, the SPECT images were analyzed using the subtraction ictal SPECT coregistered to magnetic resonance imaging (MRI) (SISCOM) technique. Subsequently, we analyzed the association between the ictal SPECT findings and those of other diagnostic modalities such as EEG, MRI, and positron emission tomography (PET). Results : Increase in cerebral blood flow on ictal SPECT involved the epileptogenic foci in 10 cases6 cases analyzed by visual assessment and 4 analyzed by the SISCOM technique. The ictal SPECT and video-EEG findings showed moderate agreement (Kappa=0.57; 95% confidence interval, 0.18-0.96). Conclusion : Ictal SPECT with prolonged injection of a tracer could provide supplementary information to localize the epileptogenic foci in infantile spasms.

Which One Is Better to Reduce the Infection Rate, Early or Late Cranioplasty?

  • Oh, Jae-Sang;Lee, Kyeong-Seok;Shim, Jai-Joon;Yoon, Seok-Mann;Doh, Jae-Won;Bae, Hack-Gun
    • Journal of Korean Neurosurgical Society
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    • v.59 no.5
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    • pp.492-497
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    • 2016
  • Objective : Decompressive craniectomy is an effective therapy to relieve high intracranial pressure after acute brain damage. However, the optimal timing for cranioplasty after decompression is still controversial. Many authors reported that early cranioplasty may contribute to improve the cerebral blood flow and brain metabolism. However, despite all the advantages, there always remains a concern that early cranioplasty may increase the chance of infection. The purpose of this retrospective study is to investigate whether the early cranioplasty increase the infection rate. We also evaluated the risk factors of infection following cranioplasty. Methods : We retrospectively examined the results of 131 patients who underwent cranioplasty in our institution between January 2008 and June 2015. We divided them into early (${\leq}90days$) and late (>90 days after craniectomy) groups. We examined the risk factors of infection after cranioplasty. We analyzed the infection rate between two groups. Results : There were more male patients (62%) than female (38%). The mean age was 49 years. Infection occurred in 17 patients (13%) after cranioplasty. The infection rate of early cranioplasty was lower than that of late cranioplasty (7% vs. 20%; p=0.02). Early cranioplasty, non-metal allograft materials, re-operation before cranioplasty and younger age were the significant factors in the infection rate after cranioplasty (p<0.05). Especially allograft was a significant risk factor of infection (odds ratio, 12.4; 95% confidence interval, 3.24-47.33; p<0.01). Younger age was also a significant risk factor of infection after cranioplasty by multivariable analysis (odds ratio, 0.96; 95% confidence interval, 0.96-0.99; p=0.02). Conclusion : Early cranioplasty did not increase the infection rate in this study. The use of non-metal allograft materials influenced a more important role in infection in cranioplasty. Actually, timing itself was not a significant risk factor in multivariate analysis. So the early cranioplasty may bring better outcomes in cognitive functions or wound without raising the infection rate.

Glass Dissolution Rates From MCC-1 and Flow-Through Tests

  • Jeong, Seung-Young
    • Proceedings of the Korean Radioactive Waste Society Conference
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    • 2004.06a
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    • pp.257-258
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    • 2004
  • The dose from radionuclides released from high-level radioactive waste (HLW) glasses as they corrode must be taken into account when assessing the performance of a disposal system. In the performance assessment (PA) calculations conducted for the proposed Yucca Mountain, Nevada, disposal system, the release of radionuclides is conservatively assumed to occur at the same rate the glass matrix dissolves. A simple model was developed to calculate the glass dissolution rate of HLW glasses in these PA calculations [1]. For the PA calculations that were conducted for Site Recommendation, it was necessary to identify ranges of parameter values that bounded the dissolution rates of the wide range of HLW glass compositions that will be disposed. The values and ranges of the model parameters for the pH and temperature dependencies were extracted from the results of SPFT, static leach tests, and Soxhlet tests available in the literature. Static leach tests were conducted with a range of glass compositions to measure values for the glass composition parameter. The glass dissolution rate depends on temperature, pH, and the compositions of the glass and solution, The dissolution rate is calculated using Eq. 1: $rate{\;}={\;}k_{o}10^{(ph){\eta})}{\cdot}e^{(-Ea/RT)}{\cdot}(1-Q/K){\;}+{\;}k_{long}$ where $k_{0},\;{\eta}$ and Eaare the parameters for glass composition, pH, $\eta$ and temperature dependence, respectively, and R is the gas constant. The term (1-Q/K) is the affinity term, where Q is the ion activity product of the solution and K is the pseudo-equilibrium constant for the glass. Values of the parameters $k_{0},\;{\eta}\;and\;E_{a}$ are the parameters for glass composition, pH, and temperature dependence, respectively, and R is the gas constant. The term (1-Q/C) is the affinity term, where Q is the ion activity product of the solution and K is the pseudo-equilibrium constant for the glass. Values of the parameters $k_0$, and Ea are determined under test conditions where the value of Q is maintained near zero, so that the value of the affinity term remains near 1. The dissolution rate under conditions in which the value of the affinity term is near 1 is referred to as the forward rate. This is the highest dissolution rate that can occur at a particular pH and temperature. The value of the parameter K is determined from experiments in which the value of the ion activity product approaches the value of K. This results in a decrease in the value of the affinity term and the dissolution rate. The highly dilute solutions required to measure the forward rate and extract values for $k_0$, $\eta$, and Ea can be maintained by conducting dynamic tests in which the test solution is removed from the reaction cell and replaced with fresh solution. In the single-pass flow-through (PFT) test method, this is done by continuously pumping the test solution through the reaction cell. Alternatively, static tests can be conducted with sufficient solution volume that the solution concentrations of dissolved glass components do not increase significantly during the test. Both the SPFT and static tests can ve conducted for a wide range of pH values and temperatures. Both static and SPFt tests have short-comings. the SPFT test requires analysis of several solutions (typically 6-10) at each of several flow rates to determine the glass dissolution rate at each pH and temperature. As will be shown, the rate measured in an SPFt test depends on the solution flow rate. The solutions in static tests will eventually become concentrated enough to affect the dissolution rate. In both the SPFt and static test methods. a compromise is required between the need to minimize the effects of dissolved components on the dissolution rate and the need to attain solution concentrations that are high enough to analyze. In the paper, we compare the results of static leach tests and SPFT tests conducted with simple 5-component glass to confirm the equivalence of SPFT tests and static tests conducted with pH buffer solutions. Tests were conducted over the range pH values that are most relevant for waste glass disssolution in a disposal system. The glass and temperature used in the tests were selected to allow direct comparison with SPFT tests conducted previously. The ability to measure parameter values with more than one test method and an understanding of how the rate measured in each test is affected by various test parameters provides added confidence to the measured values. The dissolution rate of a simple 5-component glass was measured at pH values of 6.2, 8.3, and 9.6 and $70^{\circ}C$ using static tests and single-pass flow-through (SPFT) tests. Similar rates were measured with the two methods. However, the measured rates are about 10X higher than the rates measured previously for a glass having the same composition using an SPFT test method. Differences are attributed to effects of the solution flow rate on the glass dissolution reate and how the specific surface area of crushed glass is estimated. This comparison indicates the need to standardize the SPFT test procedure.

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Patient characteristics associated with length of stay in emergency departments (응급실 재원시간과 관련된 환자의 특성)

  • Chung, Seol-Hee;Hwang, Jee-In
    • Health Policy and Management
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    • v.19 no.3
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    • pp.27-44
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    • 2009
  • The length of stay in emergency departments has been used as a quality indicator to reflect the overall efficiency of emergency care. Identifying characteristics associated with length of stay is critical to monitor overcrowding and improve efficient throughput function of emergency departments. This study examined the level of waiting time for initial assessment by physician and length of stay in emergency departments. Furthermore, we investigated the characteristics of patients' attendance associated with length of stay. An observational study was performed for a sample of 1,526 patients visiting ten nation-wide emergency departments. A structured form was designed to collect information about patients' demographics, route of admission, time and mode of arrival, triage level, cause of attendance, initial assessment time by physician, departure time, and disposition. Multiple regression analysis was performed to determine factors associated with length of stay. The average length of stay was 209.4 minutes (95% confidence interval [CI]=197.1-221.7), with a mean waiting time for initial assessment of 5.9 minutes (95% CI=5.1-6.7). After controlling for emergency department characteristics, increasing age, longer waiting times, attendance due to diseases, higher acuity, multiple diagnoses($\geq$2) and requiring admission or transfer to other health care facilities were positively associated with length of stay in emergency departments. The findings suggest that both patients' characteristics and the flow between emergency departments and parent hospitals should be taken into account in predicting length of stay in emergency departments.

Risk Assessment of Smoking for Ischemic Stroke in Koreans

  • Jung, Woo-Sang;Choi, Byung-Ok;Park, Jung-Mi;Moon, Sang-Kwan;Cho, Ki-Ho;Kim, Young-Suk;Bae, Hyung-Sup
    • The Journal of Korean Medicine
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    • v.24 no.4
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    • pp.19-24
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    • 2003
  • Background and Purposes : Smoking is a well-known risk factor for ischemic stroke. It may contribute to s1Toke by inducing the aggregation of platelets and formation of atheroma, reducing cerebral blood flow, and increasing fibrinogen. However, the relative risk varies according to different ethnicity and area. Therefore, we performed this study to assess the risk of smoking for ischemic s1Toke in Korea. Methods : Cigarette smoking habit was studied in 308 patients with ischemic s1Toke and in 348 age- and sex-matched control subjects who had no history of stroke using case control methods. In multiple logistic regression analysis, smoking had a significant value of odds ratio adjusted for hypertension, diabetes mellitus, and hyperlipidemia. Results : The adjusted odds ratio (AOR) and 95% confidence interval (CI) was significant in the medium smokers (AOR, 1.92; 95% CI, 1.11 to 3.33: p< 0.05) and heavy smokers (AOR, 2.80; 95% CI, 1.64 to 4.78: p< 0.05). Furthermore, the OR was higher in hypertensive subjects than in normotensive subjects compared to non-smokers (AOR, 1.98; 95% CI, 1.01 to 3.85: p< 0.05). Conclusions : Our findings suggest that smoking is an independent risk factor for ischemic stroke in Korea.

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Bioequivalence Assessment of Acephyll® Capsule to Surfolase® Capsule (Acebrophylline HCl 100 mg) by Liquid Chromatography Tandem Mass Spectrometry

  • Nam, Kyung-Don;Seo, Ji-Hyung;Yim, Sung-Vin;Lee, Kyung-Tae
    • Journal of Pharmaceutical Investigation
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    • v.41 no.5
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    • pp.309-315
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    • 2011
  • A sensitive and specific liquid chromatographic method coupled with tandem mass spectrometry (LC-MS/MS) was developed for the analysis of ambroxol (active moiety of acebrophylline). After acetonitrile precipitation of proteins from plasma samples, ambroxol and the domperidone (internal standard, IS) were eluted on a C18 column. The isocratic mobile phase was consisted of 10 mM ammonium acetate and methanol (10 : 90, v/v), with flow rate at 0.2 mL/min. A tandem mass spectrometer, as detector, was used for quantitative analysis in positive mode by a multiple reaction monitoring mode to monitor the m/z 379.2${\rightarrow}$264.0 and the m/z 426.2${\rightarrow}$175.1 transitions for ambroxol and the IS, respectively. Twenty four healthy Korean male subjects received two capsules (100 mg ${\times}$ 2) of either the test or the reference formulation of acebrophylline HCl in a 2 ${\times}$ 2 crossover study, this was followed by a 1week washout period between either formulation. $AUC_{0-t}$ (the area under the plasma concentration-time curve) was calculated by the linear trapezoidal rule. $C_{max}$ (maximum plasma drug concentration) and $T_{max}$ (time to reach $C_{max}$) were compiled from the plasma concentration-time data. The 90% confidence intervals for the log transformed data were acceptable range of log 0.8 to log 1.25 (e.g., log 0.8964 - log 0.9910 for $AUC_{0-t}$ log 0.8690 - log 1.0750 for $C_{max}$). The major parameters, $AUC_{0-t}$ and $C_{max}$ met the criteria of Korea Food and Drug Administration for bioequivalence indicating that Acephyll$^{(R)}$ capsule (test) is bioequivalent to Surfolase$^{(R)}$ capsule (reference).

Effective Application of Design Space Exploration in the Very Early Naval Ship Design (초기단계 함정설계시 설계영역탐색의 효과적 적용)

  • Park, Jinwon;Park, Sangil
    • Journal of the Korean Society of Systems Engineering
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    • v.11 no.2
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    • pp.61-73
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    • 2015
  • The early-phase naval ship design demands requirements synthesis rather than design synthesis, which conducts engineering design for several domains on a detailed level. Requirements synthesis focuses on creating a balanced set of required operational capabilities satisfying user's needs and concept of operations. Requirements are evolved from capability based languages to function based language by statistical exploration and engineering design which are derived in the following order: concept alternative, concept baseline, initial baseline and functional baseline. The early-phase naval ship design process can be divided into three passes: concept definition, concept exploration and concept development. Main activities and outcomes in each pass are shortly presented. Concept definition is the first important step that produces a concept baseline through extensive design space exploration promptly. Design space exploration applies a statistical approach to explore design trends of existing ships and produce feasible design range corresponding to concept alternative. It further helps naval systems engineers and operational researchers by inducing useful responses to user and stakeholders' questions at a sufficient degree of confidence and success in the very early ship design. The focus of this paper is on the flow of design space exploration, and its application to a high-speed patrol craft. The views expressed in this paper are those of the authors, and do not reflect the official policy or rule of the Navy.

The Comparison of Experimental Results of Liquid Ejector Performance to Predictions by the Computer Aided Design Program (液休용 이젝터 性能에 관한 CAD와 實驗結果와의 比較)

  • 김경근;김명환;홍영표;고상철
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.12 no.3
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    • pp.520-527
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    • 1988
  • Liquid ejectors are widely used as marine pumps, inducer stage for the boiler feed water pump, boiler recirculating pump, cooling water recirculating pump in boiling water type nuclear reactor and a deep well pump, because of their high working confidence and simplicity. Furthermore, it requires only a modest net positive suction head for cavitation-free operation and it can be installed in remote location from mechanical power source. It is not easy to presume the friction losses, because it is complicately affected by area ratio, flowrate ratio, nozzle spacing, throat length, shape of liquid ejector and so on. Therefore, the optimization of liquid ejector design is still dependent, to a large extent, on the experimental results and empirical procedures. On the design of the liquid ejector, the area ratio and the nondimensional throat length are the most important design factors among the mentioned above. In this experiment, the effects of the area ratio and the nondimensional throat length to ejector efficiency are carried out systematically by the combination of 4 kinds of motive nozzle and 2 kinds of throat length. In this paper, the present experimental results are compared with the calculated ones by the previous computer aided design program based on one dimensional flow equation. And also, an empirical equation for the working limit of liquid ejector is reported.