• Title/Summary/Keyword: Conduction Velocity

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Animal Model for the Evaluation of Repair of Injured Inferior Alveolar Nerve with Nerve Growth Factor

  • Lee, Jae-Yoon;Park, Suhyun;Heo, Hyun-A;Pyo, Sung-Woon
    • Journal of Korean Dental Science
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    • v.6 no.2
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    • pp.58-66
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    • 2013
  • Purpose: The inferior alveolar nerve (IAN) can be damaged as a result of minor oral surgical procedure such as third molar extraction or implant placement. Repair of the injured IAN involves difficulty of access, and research studies are limited to elucidating the process of regeneration by surgical methods. This study sought to establish the rabbit animal model to apply polymeric membrane functionalized with nerve growth factor after a crush lesion for the evaluation of nerve regeneration using the electrophysiologic method. Materials and Methods: The IAN of 2 adult male New Zealand white rabbits (4 nerves) were exposed bilaterally, and crush injury rendered by jeweler's forceps was applied. Nerve conduction velocity was examined electrophysiologically using electromyography before, after, and 4 weeks after the crush injury. To evaluate the regeneration, the pattern of action potential of IAN was recorded, and the characteristics of neurons were histologically observed. Result: After the crush injury, afferent activity decreased in the injured group. Electromyography could not be recorded after four weeks because tissues surrounding the injured nerve collapsed. Decrease in the mean number of axons was observed in the injured part with membrane. Conclusion: Despite the limited result, the present animal model study may provide a possible way to research on the methods of enhancing the recovery of nerve injuries in clinical situations. For clinically widespread acceptance, however, it should gain more consecutive and scientific evidences.

The Change of Postural Sway of Diabetic Neuropathy by Galvanic Vestibular Stimulation (평류전정자극에 의한 당뇨성 신경증 환자의 자세동요 변화)

  • Hwang, Tae-Yeun;Kim, Young-Nam;Kim, Tae-Youl;Park, Jang-Sung;Yoon, Se-Won
    • Journal of the Korean Academy of Clinical Electrophysiology
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    • v.3 no.1
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    • pp.71-84
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    • 2005
  • This study had performed with purposes to analyze the influence of the change of vestibular sens, visual and proprioceptive sense to the postural sway, so as to supply the necessary clinical materials through developing the physical therapeutic interventions and assessment format for the diabetic neuropathy patients. The sample consisted of fifteen diabetic neuropathy patients with sensory disorder in their lower limbs and fifteen age-matched normal control group. Then the effect of the GVS and the visual cue open and closed to the postural sway were measured by CoP. The summary of the comparison results were obtained below. In the comparison of diabetes neuropathy patients group and age matched normal control group, however diabetes neuropathy patients group had a decrease in superficial tactile sense(p<.001) and nerve conduction velocity(p<.001), they were able to control the posture and walk. So it is, diabetes neuropaty patients had more disturbance compared with AMC group on at a hard surface, particularly in the visual cue open(p<.001) and visual cue closed(p<.01). Moreover, since diabetes neuropathy patients group had more differences in visual cue open and closed(p<. 01), GVS(p<.01), it meant that they're affected largely by vestibular sense, visual sense. In addition, since there're the largest change in doubled sense disturbance such as visual cue open and closed under GVS, it meant that compensation of other senses were quite important for the diabetes neuropathy patients' postural control. In the conclusion, diabetes neuropathy patients who decrease or lose the somatosensory system, sensory training of visual and vestibular system are likely to be quite essential to control the posture and balance.

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Changes in Nerve Excitability During Neural Stretching (신경 신장 적용 시간에 따른 신경흥분성 변화)

  • Lee, Dong-Rour;Rhee, Min-Hyung;Eom, Ju-Ri;Kim, Jong-Soon
    • PNF and Movement
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    • v.16 no.2
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    • pp.287-294
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    • 2018
  • Purpose: The neurodynamic test used to implicate symptoms arising from the nerve is proposed to selectively increase the strain of the nerve without increasing the strain of adjacent tissue, although this has not yet been established in the time of nerve tension application. This study aimed to investigate the acute effects of nerve stretching time on nerve excitability using compound nerve action potential (CNAP) analysis. Methods: Thirty healthy young adults (mean age=23.10 years) with no medical history of neurological or musculoskeletal disorder voluntarily participated in this study. Nerve excitability was assessed using the median nerve conduction velocity test. The amplitude of the CNAP was measured under three conditions: resting phase (supra-maximal stimulus, without nerve stretching), baseline phase (two-thirds of the supra-maximal stimulus, without nerve stretching), and stretch phase (two-thirds of the supra-maximal stimulus, with 1-5 minutes nerve stretching). One-way repeated measures ANOVA was conducted to compare the latency and amplitude of CNAP. A post-hoc test was analyzed using the contrast test. Results: The latency was significantly delayed after 1 min. of nerve stretching in comparison with the baseline test. However, no significant difference was found during the nerve stretching (1-5 min.). The amplitude was significantly increased by nerve stretching. Conclusion: Nerve stretching can induce nerve excitability without any nerve injury. Based on the results, more than 1 min. of nerve stretching as a neurodynamic test can be a useful method in the clinical setting.

F-Wave Analysis in Patients with Clinically Diagnosed Carpal Tunnel Syndrome (임상적으로 진단된 수근관증후군 환자에서 F파 분석)

  • Kim, Seong-Hee;Yoo, Bong-Goo;Kim, Kwangsoo;Yoo, Kyung-Moo
    • Annals of Clinical Neurophysiology
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    • v.4 no.2
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    • pp.108-113
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    • 2002
  • Background and Objective : Carpal tunnel syndrome (CTS) is the most common mononeuropathy encountered in clinical practice. No single procedure or group of procedures has demonstrated adequate sensitivity. F-wave study in CTS is very rarely reported. To determine the diagnostic usefulness of new parameters of F-wave and comparative study of F-wave parameters of median and ulnar nerves in patients with CTS. Methods : F-wave responses of median and ulnar nerves were analyzed from 27 patients with clinically diagnosed CTS and 22 age and gender-matched normal control. Conventional F-wave parameters were studied. Also, the usefulness of new parameters such as mean and maximal ulnar-median F-wave latency differences, ulnar-median F-wave persistence and chronodispersion differences, median/ulnar F-wave amplitude ratio, and F-wave conduction velocity (FCV) using mean and maximal latency were assessed. Results : Compared with controls, median F-wave minimal, maximal and mean latencies, mean F-wave amplitude/M-wave amplitude, minimal, mean and maximal ulnar-median F-wave latency differences, and FCVs using minimal, maximal and mean latency were significant (P<0.05~0.001). Median F-wave minimal, maximal and mean latencies, mean ulnar-median F-wave latency difference, and FCVs using minimal, maximal and mean latency showed high sensitivity and specificity. Mean ulnar-median F-wave latency difference and FCVs using maximal and mean latency were new parameters. Conclusion : New F-wave parameter including mean ulnar- median F-wave latency difference and FCVs using maximal and mean latency may be a useful to assess the CTS. Also, median F-wave minimal, maximal and mean latencies, and FCV using minimal latency may be included in routine diagnostic tests in CTS.

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IN VIVO EFFECTS OF DENTIN BONDING AGENTS ON DENTINAL FLUID MOVEMENT AND INTRADENTAL NERVE ACTIVITY (In vivo에서 상아질 접착제 도포가 상아세관액 이동과 치수신경활동에 미치는 영향)

  • Son, Ho-Hyun;Lee, Kwang-Won;Park, Soo-Jung
    • Restorative Dentistry and Endodontics
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    • v.21 no.1
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    • pp.425-435
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    • 1996
  • The effect of application of dentin bonding agent to the exposed dentin on the intradental nerve activity (INA), dentinal fluid movement and sealing of the dentinal tubules, was investigated in this study. The INA was recorded from the single pulp nerve unit dissected from the inferior alveolar nerve. And specimen of dentin was observed by SEM. Dentinal fluid 'movement through exposed dentin surface was measured before and after the application of dentin bonding agent. 1. Eight Ao-fiber units (conduction velocity: $8.0{\pm}4.0m$/sec) were identified. 4M NaCl evoked an irregular burst of action potentials which ceased immediately after washing. 2. In 4 $A{\delta}$-fiber units, appliction of All Bond 2 completely abolished the INA induced by 4M NaCl. Also, application of Scotchbond Multipurpose(SBMP) totally abolished the INA induced by 4M NaCl in 4 $A{\delta}$-fiber units. 3. Before the application of dentin bonding agent, outward dentinal fluid movement of $10.2{\pm}5.7\;pl{\cdot}s^{-1}{\cdot}mm^{-2}$ was obsered. But after the application of dentin bonding agent the movement of dentinal fluid was stopped. 4. The gap width of 2-$3{\mu}m$ was formed between exposed dentin and adhesive resin in the specimens applied with dentin bonding agents of All Bone 2 and SBMP. But the formation of hybrid layer and the penetration of resin into were dentinal tubules were not clearly observed in interface between dentin and adhesive resin.

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Prediction of Spectral Phonon Mean Free Path Contribution to Thermal Conduction in Silicon Using Phonon Kinetic Theory (포논 기체 운동론을 이용한 실리콘 내 포논 평균자유행로 스펙트럼 열전도율 기여도 예측)

  • Jin, Jae Sik
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.41 no.5
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    • pp.341-346
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    • 2017
  • Knowing the mean free paths (MFPs) of thermal phonons is an essential step in performing heat transfer analysis for nanomaterials, and in determining the optimum design for tailoring the heat transfer characteristics of nanomaterials. In this study, we present a method that can be used to calculate accurately the phonon MFP spectra of nanostructures based on simple phonon kinetic theory. Here, the kinetic theory may be employed by extracting only the diffusive-transport part of the phonon spectrum (i.e., the MFPs are less than a thermal length). By considering phonon dispersion and polarization effects, the phonon MFP distributions of silicon at room temperature are calculated from phonon transport properties and the spectral MFP. Our results are validated by comparison with those of the first principle and MFP spectroscopy data.

Energy effects on MHD flow of Eyring's nanofluid containing motile microorganism

  • Sharif, Humaira;Naeem, Muhammad N.;Khadimallah, Mohamed A.;Ayed, Hamdi;Bouzgarrou, Souhail Mohamed;Al Naim, Abdullah F.;Hussain, Sajjad;Hussain, Muzamal;Iqbal, Zafar;Tounsi, Abdelouahed
    • Advances in concrete construction
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    • v.10 no.4
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    • pp.357-367
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    • 2020
  • The impulse of this paper is to examine the influence of unsteady flow comprising of Eyring-Powell nanofluid over a stretched surface. This work aims to explore efficient transfer of heat in Eyring-Powell nanofluid with bio-convection. Nanofluids possess significant features that have aroused various investigators because of their utilization in industrial and nanotechnology. The influence of including motile microorganism is to stabilize the nanoparticle suspensions develop by the mixed influence of magnetic field and buoyancy force. This research paper reveals the detailed information about the linearly compressed Magnetohydrodynamics boundary layer flux of two dimensional Eyring-Powell nanofluid through disposed surface area due to the existence of microorganism with inclusion the influence of non- linear thermal radiation, energy activation and bio-convection. The liquid is likely to allow conduction and thickness of the liquid is supposed to show variation exponentially. By using appropriate similarity type transforms, the nonlinear PDE's are converted into dimensionless ODE's. The results of ODE's are finally concluded by employing (HAM) Homotopy Analysis approach. The influence of relevant parameters on concentration, temperature, velocity and motile microorganism density are studied by the use of graphs and tables. We acquire skin friction, local Nusselt and motil microorganism number for various parameters.

Simple Decompression of the Ulnar Nerve for Cubital Tunnel Syndrome

  • Cho, Yong-Jun;Cho, Sung-Min;Sheen, Seung-Hoon;Choi, Jong-Hun;Huh, Dong-Hwa;Song, Joon-Ho
    • Journal of Korean Neurosurgical Society
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    • v.42 no.5
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    • pp.382-387
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    • 2007
  • Objective : Cubital tunnel syndrome is the second most common entrapment neuropathy of the upper extremity. Although many different operative techniques have been introduced, none of them have been proven superior to others. Simple cubital tunnel decompression has numerous advantages, including simplicity and safety. We present our experience of treating cubital tunnel syndrome with simple decompression in 15 patients. Methods : According to Dellon's criteria, one patient was classified as grade 1, eight as grade 2, and six as grade 3. Preoperative electrodiagnostic studies were performed in all patients and 7 of them were rechecked postoperatively. Five patients of 15 underwent simple decompression using a small skin incision (2 cm or less). Results : Preoperative mean value of motor conduction velocity (MCV) within the segment (above the elbow-below the elbow) was $41.8{\pm}15.2\;m/s$ and this result showed a decrease compared to the result of MCV in the below the elbow-wrist segment ($57.8{\pm}6.9\;m/s$) with statistical significance (p<0.05). Postoperative mean values of MCV were improved in 6 of 7 patients from $39.8{\pm}12.1\;m/s$ to $47.8{\pm}12.1\;m/s$ (p<0.05). After an average follow-up of $4.8{\pm}5.3$ months, 14 patients of 15 (93%) reported good or excellent clinical outcomes according to a modified Bishop scoring system. Five patients who had been treated using a small skin incision achieved good or excellent outcomes. There were no complications, recurrences, or subluxation of the ulnar nerve. Conclusion : Simple decompression of the ulnar nerve is an effective and successful minimally invasive technique for patients with cubital tunnel syndrome.

An early diagnostic method for diabetic neuropathy using $TcpO_2$ ($TcpO_2$를 이용한 신경병성 당뇨환자 조기진단)

  • Kim, Jin-Tae;Kim, Sung-Woo;Nam, Ki-Chang;Park, Joong-Hoon;Kim, Deok-Won
    • Proceedings of the KIEE Conference
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    • 2006.10c
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    • pp.232-234
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    • 2006
  • Diabetic neuropathy is one of the most common diabetic complications. In clinical practices, nerve conduction velocity (NCV) has been used as a standard method for diagnosing diabetic neuropathy. However, it applies maximum of 100mA electric stimulus to nerves causing stress and pain to patients. In this study. as a non-invasive method, $TcpO_2$ was utilized to investigate the difference and relationship between $TcpO_2$ and $SpO_2$ of normal and diabetic neuropathy subjects. In addition, a new method of diagnosing diabetic neuropathy using $TcpO_2$ is suggested. 50 normal subjects and 50 diabetic patients with neuropathy diagnosed by NCV participated in this study. Parameters used in this study were $TcpO_2,\;TcpCo_2$, and $SpO_2$. As a result of the $TcpO_2$ measurements, statistical significances were found from $TcpO_2$ of hands and feet from normal and patients group (p<0.01). $SpO_2$ measured from index finger of normal and patient groups showed no statistical significance (p>0.05). On the other hand, $SpO_2$ measured from great toes of normal and patient group showed statistical significance (p<0.01). Correlation coefficient between $SpO_2$ of finger and $TcpO_2$ of hand was 0.400 (p<0.01) and $SpO_2$ of toe and $TcpO_2$ of foot was 0.471 (p<0.01). Both correlation values were statistically significant. Sensitivities and specificities of the $TcpO_2$ method were found to be 66 % and 92 %, respectively. If suggested $TcpO_2$ method is used periodically. prevention and early diagnosis of diabetic neuropathy is possible.

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Development of Surface Myoelectric Sensor for Myoelectric Hand Prosthesis

  • Choi, Gi-Won;Moon, In-Hyuk;Sung, So-Young;Lee, Mynug-Joon;Chu, Jun-Uk;Mun, Mu-Seong
    • 제어로봇시스템학회:학술대회논문집
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    • 2005.06a
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    • pp.1268-1271
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    • 2005
  • This paper proposes a compact-sized surface myoelectric sensor for myoelectric hand prosthesis. To fit the surface myoelectric sensor in the socket of the myoelectric hand prosthesis, the sensor should be a compact size. The surface myoelectric sensor is composed of a skin interface and a single processing circuit that are mounted on a single package. Since the skin interface has one reference and two input electrodes, and the reference electrode is located in middle of two input electrodes, we propose two types of sensors with the circle- and bar-shaped reference electrode, but all input electrodes are the bar-shaped. The metal material used for the electrodes is the stainless steel (SUS440) that endures sweat and wet conditions. Considering conduction velocity and median frequency of the myoelectric signal, we select the inter-electrode distance (IED) between two input electrodes as 18mm, 20mm, and 22 mm. The signal processing circuit consists of a differential amplifier with band pass filter, a band rejection filter for rejecting 60Hz power-line noise, amplifiers, and a mean absolute value circuit. We evaluate the proposed sensor from the output characteristics according to the IED and the shape of the reference electrode. From the experimental results we show the surface myoelectric sensor with the 18mm IED and the bar-shaped reference electrode is suitable for the myoelectric hand prosthesis.

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