• 제목/요약/키워드: Conducted Susceptibility

검색결과 501건 처리시간 0.03초

Review of epidemiological studies on air pollution and health effects in children

  • Lee, Jong-Tae
    • Clinical and Experimental Pediatrics
    • /
    • 제64권1호
    • /
    • pp.3-11
    • /
    • 2021
  • There is a growing body of literature on the adverse health effects of ambient air pollution. Children are more adversely affected by air pollution due to their biological susceptibility and exposure patterns. This review summarized the accumulated epidemiologic evidence with emphasis on studies conducted in Korea and heterogeneity in the literature. Based on systematic reviews and meta-analyses, there is consistent evidence on the association between exposure to ambient air pollution and children's health, especially respiratory health and adverse birth outcomes, and growing evidence on neurodevelopmental outcomes. Despite these existing studies, the mechanism of the adverse health effects of air pollution and the critical window of susceptibility remain unclear. There is also a need to identify causes of heterogeneity between studies in terms of measurement of exposure/outcome, study design, and the differential characteristics of air pollutants and population.

디지털 리터러시와 건강 임파워먼트가 노인의 의사와의 소통에 미치는 영향 연구: 건강신념의 조절효과를 중심으로 (The Effects of Digital Literacy and Health Empowerment on Elders' Communication with Doctors: Focusing on Moderating Effect of Health Beliefs)

  • 안순태;임유진;정순둘
    • 지역사회간호학회지
    • /
    • 제33권1호
    • /
    • pp.53-62
    • /
    • 2022
  • Purpose: This study explored the effects of the elderly group's digital literacy and health empowerment on communication with doctors, considering moderating effect of health beliefs about chronic diseases. Methods: A one-on-one interview survey was conducted with 500 older adults in South Korea. The main variables were digital literacy, health empowerment, communication with doctors, and health belief of chronic diseases. Results: The interaction effect between health empowerment and susceptibility, and health empowerment and perceived barrier were significant. Conclusion: Communication with doctors greatly increased when the elders had high levels of health empowerment and low levels of susceptibility. Also, communication with doctors greatly increased when the elders had high levels of health empowerment and low levels of perceived barriers.

최근 8년간 혈액배양에서 분리된 미생물의 항균제 감수성 양상: 2010~2017 (Antimicrobial Susceptibility Patterns of Microorganisms Isolated from Blood Culture during the Last 8 Years: 2010~2017)

  • 김재수;공소영;김종완;임인수;김가연
    • 대한임상검사과학회지
    • /
    • 제51권2호
    • /
    • pp.155-163
    • /
    • 2019
  • 검사는 2010년부터 2017년까지 162,551 검체중 11,233 검체(6.9%)가 배양 양성이었으며, 이중 11,865 균주가 배양되었다. 배양된 균종 중 그람양성구균이 47.8%, 그람음성간균 38.8%, 그람양성간균 4.2%, 진균 6.8%, 혐기성균이 2.3%를 나타냈다. 배양결과를 성별로 비교하면 남성에서 분리된 균이 55.0% (2,732/4,969)로 여성에서 분리된 45.0% (2,237/4,969) 보다 많았다. 또한 연령별로는 70대가 28.7% (1,426/4,969)로 가장 많이 분리되었으며, 10대의 1.2% (62/4,969)와 많은 차이를 보였다. MRSA에 대한 내성률은 2016년 66.7%에서 2017년에는 46.8%로 많은 감소를 보였으며, E. faecium의 vancomycin 내성률은 35.0% (48/137)로 나타났다. 한편 장내세균에서 E. coli의 ESBL 양성률은 2010년 17.2%에서 2017년 28.8%로 증가하였으나, K. pneumoniae에서는 오히려 양성률이 감소하였다. P. aeruginosa의 MRPA는 11.8% (14/119), A. baumannii에서의 MRAB는 64.3% (161/252)로 높은 내성을 나타내었다. 혈액 검체에서 분리되는 미생물의 균종과 항균제 감수성 양상은 시기, 지역 및 대상환자 등에 따라 다르므로 병원균을 주기적으로 분석하고 이에 대한 항균제 감수성 정도의 변화양상을 파악하는 것이 병원에서 내성균의 감독과 조절에 큰 도움이 될 것으로 판단된다.

아리랑1호 위성 ETB의 전도성 전자파 환경 시험결과 분석 (A Analysis on the Result of CE/CS Test on the KOMPSAT-I ETB)

  • 임성빈;천용식
    • 한국전자파학회논문지
    • /
    • 제12권2호
    • /
    • pp.184-192
    • /
    • 2001
  • 본 논문에서는 아리랑 1호 개발단계에서 위성의 전기/전자적 기능 시험을 수행하기 위해 개발 모델로 구성된 Electrical Test Bed(ETB) 플랫폼에서 수행한 전도성 방출 및 전도성 감응시험 결과를 분석하였다. 전도성 전자파환경시험은 전력공급장지(Power control unit)로부터 위성을 구성하고 있는 각각의 하드웨어와DC 전원을 공급하기 위하여 스위치가 동작하는 순간, 전력 및 신호선을 통하여 전달하게 될 노이즈의 순시 파형을 시간 영역에서 측정하고, 모든 하드웨어에 전력이 공급되어 정상상태로 동작하는 동안에 발생하는 노이즈특성을 시간영역과 주파수 영역에서의 스펙트럼을 10 Hz에서 100hz까지 스캐닝하여 그 레벨을 측정하여 결과를 분석한 결과를 이용하여 6 dB이상의 시스템 마진을 더한 결과를 노이즈 소스로 공급하여 하드웨어의 오동작 및 하드웨어의 손상이 없음을 검증하였다. 본 시험은 아리랑 1호 위성의 공동개발을 수행한 미국 TRW 사의 위성체 조립시험장에서 수행되었다.

  • PDF

금풍광산 광화대에 대한 전기비저항 토모그래피탐사 자료의 복합해석 (Integrated Interpretation of ERT Data from the Mineralized Zone in Geumpung Mine)

  • 정연호;변중무
    • 지구물리와물리탐사
    • /
    • 제10권4호
    • /
    • pp.322-331
    • /
    • 2007
  • 본 연구에서는 충북 제천 소재 금풍광산 광화대에 대해 지표 물리탐사결과 탐지된 이상대의 원인규명 및 광화대의 부존특성을 파악할 목적으로 시추공 비저항 토모그래피탐사를 적용하였다. 경사 시추공으로 인한 토모그래피탐사 자료의 겉보기 비저항값의 보정을 위하여 정확한 전극위치를 파악코자 공곡측정을, 시추공 주변부에 대한 물성정보를 얻고자 전기비저항 및 자연감마 등의 물리검층을, 코어시료에 대해 전기비저항값과 물성들 간의 상관성을 파악코자 공극률, 밀도, 대자율, 전기비저항 등의 물성시험을 수행하였으며, 전도성 광물의 품위와 전기비저항과의 관계를 규명하고자 품위분석을 하였다. 물성시험 결과, 본 연구지역과 같은 전도성황화광체 부존지역에서는 전기비저항이 공극률, 함수율과 같은 물성보다는 대자율, 품위와 같은 물성에 압도적으로 지배되는 것으로 확인되었으며, 비저항 토모그래피 탐사자료의 역산 결과, 비저항 분포 단면이 물리검층 자료 및 주상도와 일치하는 양호한 결과를 얻었다. 따라서 비저항 토모그래피탐사가 전도성 황화광체의 부존 특성 파악에 탁월한 효과를 보이는 것을 알 수 있었다.

충남지역 도축돈의 폐병변으로 부터 분리한 Actinob acillus pleuropneumoniae의 생물학적 및 면역학적 특성 (Studies on biochemical and immunological properties of Aetinobacillus pleuropneumoniae Isolated from the slaughter pigs with respiratory lesions in chungnam province)

  • 이종훈;안신욱;정영재;장경수;전무형
    • 한국동물위생학회지
    • /
    • 제20권1호
    • /
    • pp.103-125
    • /
    • 1997
  • An epidemiologic study on pleuropneumonia in the slaughter pigs(Chonan and Asan area, Chungnam province, Korea) during the period of January 1994 through December 1995 was conducted. Isolation of A pleuropneumoniae was attempted in 425 pigs with pneumonic lesions. Biochemical properties, antimicrobial susceptibility, serotypes and pathogenicity of isolated A pleuropneumoniae were investigated. In addition, outer membrane protein(OMP) of the Isolates were extracted to determine its properties and immunogenicity in both mice and piglets The results obtained through this study were summarized as followed ; 1. Of 3, 395 slaughter pigs, pleuropneumonia was observed in 425 pigs(10.6%). A pleuropneumoniae was isolated from 22 pigs(5.2%) out of 425 pigs with pneumonic lesions. The biochemical properties of all isolates were same as those of reference A pleuropneumoniae strain. Among 22 isolates, 9, 1 and 12 isolates were serovar 2, 3 and 5, respectively. 2. The results of antimicrobial susceptibility test revealed that the isolates showed high susceptibility to ciprofloxacin and cephalothin, moderate susceptibility to amikacin, gentamicin, kanamycin and streptomycin, and low susceptibility to erythromycin, tylosin and sulfadimethoxin. 3. The isolates were varied in pathogenicity to mice. Median lethal dose of LE9402(serovar 2) and LE9511(serovar 5) were $9.2{\times}10^7$ CFU and $2.8{\times}10^7$%CFU, respectively. Specific pneumonic lesions were observed from the infected mice with clinical signs. Bacteria recovery rate was high in the lung, but low In heart blood and tracheas. 4. Serovar 2 was found to be more pathogenic than serovar 5 in guinea pig. Mortality on guinea pigs inoculated with serovar 2($5.4{\times}10^8-5.4{\times}10^6$CFU) and serovar 5($2.8{\times}10^8-2.8{\times}10^6$ CFU) was 20~40% and 40~80%, respectively. A severe hemorrhagic lesions and focal pneumonic lesions were observed from dead guinea pigs. Bacteria recovery rate was relatively higher in the lung than that of other organs. 5. In the SDS-PAGE analysis, OMP-enriched fractions of both isolates and reference strains contain common peptide bands equivalent to molecular weight of 17, 27, 42, 52 and 95Kd. In addition to common peptide bands, the bands which are specific to each isolate were also observed. The profiles of Sephadex G25 fractions showed 3 major peaks. The common peptide bands which were observed by SDS-PAGE of the crude OMPs were found in the peaks 1 and 2. 6. The OMPs extracted from serovar 2(LE9402) and serovar 5(LE9511) provided high level of protection in mice(70~80%) and pigs(100%). All animals inoculated with OMPs were seroconverted, showing micro-agglutination titer of 640 to 1280.

  • PDF

The XRCC1 Arg399Gln Genetic Polymorphism Contributes to Hepatocellular Carcinoma Susceptibility: An Updated Meta-analysis

  • Pan, Yan;Zhao, Lei;Chen, Xing-Miao;Gu, Yong;Shen, Jian-Gang;Liu, Lu-Ming
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제14권10호
    • /
    • pp.5761-5767
    • /
    • 2013
  • The potential correlation of X-ray repair cross-complementing group 1 (XRCC1) Arg399Gln polymorphism with hepatocellular carcinoma (HCC) susceptibility is ambiguous. Taking account of inconsistent results of previous meta-analyses and new emerging literatures, we conducted a meta-analysis covering 15 case-control datasets to evaluate the relationship. Relevant studies from Medline, Embase and CNKI were retrieved. A fixed-effect model or a random-effect model, depending on between-study heterogeneity, were applied to estimate the association between XRCC1 polymorphism Arg399Gln and HCC risk with the results presented as odds ratios (ORs) and 95% confidence intervals (95% CIs). In accordance with Hardy-Weinberg equilibrium, 15 studies with data for 6,556 individuals were enrolled in this systematic review. For overall HCC,thr XRCC1 polymorphism Arg399Gln was significantly associated with HCC susceptibility in a homozygote model as well as in a dominant model (G/G vs. A/A, OR=1.253, p=0.028; G/G+A/G vs. A/A, OR= 1.281, p=0.047, respectively), but not in a heterozygote model (A/G vs. A/A, OR=1.271, p=0.066) or a recessive model (G/G vs. A/G + A/A, OR= 1.049, p=0.542). Similar results were also observed on stratification analysis by ethnicity (A/G vs. A/A, OR=1.357, p=0.025; G/G vs. A/A, OR=1.310, p=0.011; G/G+A/G vs. A/A, OR= 1.371, p=0.013). However, no potential contribution of XRCC1 Arg399Gln polymorphism to HCC susceptibility in HBV/HCV subgroups was identified. No publication bias was found in this study. In conclusion, the XRCC1 Arg399Gln polymorphism contributes to HCC susceptibility. Due to the lack of studies in Western countries, further large-sample and rigorous studies are needed to validate the findings.

Environmentally Assisted Crack Growth Behavior of SA508 Cl.3 Pressure Vessel Steel

  • Kim, Jun-Hwan;Kim, In-Sup
    • 한국원자력학회:학술대회논문집
    • /
    • 한국원자력학회 1998년도 춘계학술발표회논문집(2)
    • /
    • pp.154-159
    • /
    • 1998
  • In order to assess the susceptibility of the environmentally assisted cracking(EAC) on SA508 Cl.3 steel in primary water condition, potential step test and slow strain rate test(SSRT) were conducted in a simulated crack tip condition. In this test, anodic dissolution was dominant in the crack tip environments. Proposed simple dissolution model is a modification of Hishida's anodic dissolution model at the plastic zone. One can predict actual crack growth rate with the smooth specimen through this model.

  • PDF

낙뢰 간접영향에 대한 항공전자장비의 환경시험 (Environmental Test of Avionics Equipment for Lightning Indirect Effect)

  • 정덕영;양현덕
    • 항공우주시스템공학회지
    • /
    • 제7권2호
    • /
    • pp.55-59
    • /
    • 2013
  • Before avionics equipment are installed in aircraft, several environmental tests such as temperature, vibration, lightning, fire etc. must be conducted. One of the environmental tests is to substantiate protection designs of lightning indirect effect. It can be showed through RTCA DO-160G, section22 "Lightning Induced Transient Susceptibility" test. An additional test of aircraft level is required as well after installation of avionics equipment.

Factors Associated with Adherence to Colorectal Cancer Screening among Moderate Risk Individuals in Iran

  • Taheri-Kharameh, Zahra;Noorizadeh, Farsad;Sangy, Samira;Zamanian, Hadi;Shouri-Bidgoli, Ali Reza;Oveisi, Helaleh
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제16권18호
    • /
    • pp.8371-8375
    • /
    • 2016
  • Background: Colorectal cancer is one of the most common neoplasms in Iran. Secondary prevention (colorectal cancer screening) is important and a most valuable method of early diagnosis of this cancer. The objectives of this study were to determine the factors associated with colorectal cancer screening adherence among Iranians 50 years and older using the Health Belief Model. Materials and Methods: This cross-sectional study was conducted from June 2012 to May 2013. A convenience sample of 200 individuals aged 50 and older was recruited from the population at outpatient clinics in teaching hospitals. Data gathering tools were the Champions health belief model scale (CHBMS) with coverage of socio-demographic background and CRC screening information. Multiple logistic regression was performed to identify factors associated with colorectal cancer screening adherence. Results: The mean age of participants was $62.5{\pm}10.8$ and 75.5% were women. A high percentage of the participants had not heard or read about colorectal cancer (86.5%) and CRC screening (93.5%). Perceived susceptibility to colorectal cancer had the lowest percentage of all of the subscales. Participants who perceived more susceptibility (OR =2.99; CI 95%: 1.23-5.45) and reported higher knowledge (OR =1.29; CI 95%: 1.86-3.40) and those who reported fewer barriers (OR =.37; CI 95%:.21-.89), were more likely to have carried out colorectal cancer screening. Conclusions: Our findings indicated that CRC knowledge, perceived susceptibility and barriers were significant predictors of colorectal cancer screening adherence. Strategies to increase knowledge and overcome barriers in risk individuals appear necessary. Education programs should be promoted to overcome knowledge deficiency and negative perceptions in elderly Iranians.