• Title/Summary/Keyword: Conditional nested variables

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A Sequence of Models for Categorical Data with Compound Scales (복합척도의 범주형 자료에 대한 연속 모형)

  • 최재성
    • The Korean Journal of Applied Statistics
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    • v.14 no.1
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    • pp.103-110
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    • 2001
  • This paper considers a multistage experiment. Response scales can be same or different from stage to stage. When variables are of nested structure, the response variable at each stage can be defined conditionally. For analysing such data with compound scales, this paper suggests a sequnce of dependence models and shows how to set up a sequence of models for the driver's liscense test data.

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Lifestyle factors related to glucose control for diabetes management strategies: Nested case control design using KNHANES data (당뇨병 관리전략을 위한 혈당조절 관련 생활습관 요인: 국민건강영양조사 활용 코호트내 환자-대조군 연구)

  • Kim, Yunjung;Cho, Eunhee
    • Journal of the Korea Convergence Society
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    • v.10 no.11
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    • pp.501-510
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    • 2019
  • This study aimed to find health related lifestyle factors that influence glycemic control for diabetes mellitus (DM) management strategies. This study used nested case-control design with matching variables that were not controlled by individuals such as age, sex, insulin or oral hypoglycemic agent (OHA) use, disease duration, education level and household income. This study analyzed 983 subjects with type 2 DM who enrolled in the $7^{th}$ (2016-2017) Korean National Health and Nutrition Examination Survey (KNHANES). The target HbA1c level of controlled glucose was defined as less than 6.5%, and 289 (30%) were achieved. Conditional multivariable logistic regression analysis was performed to find self-control factors associated with HbA1c levels. The results statistically significant for variables such as duration of diabetes, insulin or OHA use in overall cohort and body mass index (BMI), smoking and fundus Examination in matched cohort. These results are expected to provide as evidence for the intensive care criteria(disease duration, drug use) and lifestyle management strategy(BMI, smoking, fundus examination).

Fasting Serum Glucose Level and Gastric Cancer Risk in a Nested Case-control Study (공복 혈당과 위암 발생 위험에 관한 코호트 내 환자-대조군 연구)

  • Jun, Jae-Kwan;Gwack, Jin;Park, Sue-Kyung;Choi, Yun-Hee;Kim, Yeon-Ju;Shin, Ae-Sun;Chang, Soung-Hoon;Shin, Hai-Rim;Yoo, Keun-Young
    • Journal of Preventive Medicine and Public Health
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    • v.39 no.6
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    • pp.493-498
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    • 2006
  • Objectives : Diabetes has been reported as a risk factor for several cancers. However, the association between diabetes and gastric cancer has been inconsistent. The aim of this study was to evaluate the association between the fasting serum glucose level and gastric cancer risk in Korea. Methods : Among the members of the Korean Multi-Center Cancer Cohort (KMCC) from 1993 to 2004, a total of 100 incident gastric cancer cases were ascertained until December 31, 2002 and 400 controls were matched according to age, sex, and year and area of enrollment. Of the eligible subjects, those without fasting serum glucose level information were excluded, with a total of 64 cases and 236 controls finally selected. On enrollment, all subjects completed a baseline demographic and lifestyle characteristics questionnaire, and had their fasting serum glucose level measured. The Helicobacter pylori infection status was determined by an immunoblot assay using long-term stored serum. The odds ratios (ORs) were estimated using conditional and unconditional logistic regression models adjusted for the H. pylori infection status, smoking, drinking, education, follow-up period and matching variables. Results : The ORs for risk of gastric cancer according to the serum glucose level were 1.33 [95% CI=0.50-3.53] and 1.66 [95% CI=0.55-5.02] for the categories of 100-125 and 126 mg/dL or greater, respectively, compared to the category of less than 100 mg/dL. No increased risk of gastric cancer according to the serum glucose level was found (p-trend=0.337). Conclusions : This study provides no evidence for an association of the serum glucose level with gastric cancer.