• 대한기계학회논문집A
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• 제21권2호
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• pp.209-216
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• 1997

A feature is well known as a medium to integrate CAD, CAPP and CAM systems. For a part drawing including both simple geometry and compound geometry, a process plan such as the selection of process, machine tool, cutting tool etc. normally needs simple geometry data and non-geometry data of the feature as the input. However, a extended process plan such as the generation of process sequence, operation sequence, jig & fixture, NC program etc. necessarily needs the compound geometry data as well as the simple geometry data and non-geometry data. In this paper, we propose a feature data model according to the result of analyzing necessary data, including the compound geometry data, the simple geometry data and the non-geometry data. Also, an example of the feature data model in milling process planning is described.

• 한국정밀공학회지
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• 제16권5호통권98호
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• pp.66-73
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• 1999

To enhance machining efficiency, tool exchange time have to be reduced. Most automatic tool changer is made up of compound cam and motor. it is not easy to design and manufacture compound cam, and it has no flexibility. But if servo motor is used, it is easy to changer is developed with servo motor, clutch, ball-screw and spline nut. Experimental results show that automatic tool changer designed with servo motor have good faculties.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2000년도 추계학술대회 논문집
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• pp.559-562
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• 2000

Bending is one of the most common cold-stamping operations, recently it is many used to produce structural frame. Depending on the shape and dimensions of complex structural frame, a successive bending operation with simple dies may be economic. But, in this paper, it has been focused to reduce the bending operations by a successive-action compound die. Designed compound-die consists of blank-holder, cam, wedge and etc. In the result, this compound-die for structural frame enabled that it makes seven bending processes into one process, and improved productivity.

• 한국정밀공학회지
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• 제19권9호
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• pp.125-132
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• 2002

We use a compound-cam twin arm structure and random tool access method to achieve a faster ATC (Automatic Tool Changer) system for the accurate position and rotation control of a tool magazine and an exchange am. Based on the data obtained from various sensors, it is possible to follow the sequence of commands in each control step for an exchange arm. However, it is not so easy to reduce the exchange time of the system because of the slow responses of the sensors and execution mode delays of PLC (Programmable Logic Controller) scan time. In this paper, we propose a new programmed limit-switch position control method to obtain the shortest possible delays for the random tool access method and compound-cam twin arm structure. With some experimental results, we have achieved below 0.9sec tool exchange time with the proposed method.

• 대한기계학회논문집A
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• 제37권1호
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• pp.55-60
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• 2013

컴파운더 보우는 리커브 보우와 비교하여 케이블 및 캠 풀리로 구성되는 지레시스템을 사용하여, 궁사가 보우를 최대 위치로 당기기 위해 필요로 하는 힘을 줄이는 동시에 더 많은 에너지를 축적할 수 있도록 해준다. 지금까지 컴파운더 보우의 효율 및 성능을 향상시키기 위해 경험적인 방법에 기초하여 많은 특허가 제안되었지만, 해석적인 방법에 대한 연구는 별로 없었다. 그러므로 본 연구에서는 컴파운더 보우 지레 시스템의 기구학적인 해석을 위한 방법을 제안하여 지레시스템의 캠 형상 및 보우 날개의 재질변화에 따른 효과를 설계자가 쉽게 예측할 수 있도록 하고자 한다.

• 한국미생물·생명공학회지
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• 제17권2호
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• pp.100-108
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• 1989

중요 난분해성 환경오염물질인 방향족 화합물들을 효과적으로 분해 이용할 수 있는 미생물 균주를 토양에서 분리하여 효율적인 산업폐수처리제 제조의 기초 균주로 활용할 수 있도록 균주 육종을 통한 우수 분해균주 개발에 관한 연구를 실시하였다. 총66점의 시료로부터 benzoate 분해균주, 10주, salicylate, 10주, m-toluate, 6주와 camphor, 10주 등 총 36주의 방향족 화합물 분해균주를 분리하였다. Benzoate 분해균주 중 Pseudomonas속 균주로 확인된 Ben 6에서 유래된 고활성 변이주 Ben6-2는 800$\mu\textrm{g}$/$m\ell$의 benzoate 농도에서도 높은 분해활성을 유지, 48시간 진탕배양했을 때 시간당 평균 기질 분해율이 11mg/$\ell$/hr이었고 최종 기질 분해율은 89%이었다. Salicylate와 m-toluate 분해균인 Pseudomenase속 5317과 7012 균주는 2,200$\mu\textrm{g}$/$m\ell$ 이상의 기질농도에서도 높은 활성을 유지, 48시간 배양으로 각각 98.5%와 81.7%의 기질 분해율을 보였다. m-Toluate 자화능이 없는 camphor 분해 분리균인 Cam 10 Pseudomonas속 균주로부터 1,000$\mu\textrm{g}$/$m\ell$의 m-toluate가 첨가된 배지에서 생육할 수 있는 Cam 1040 변이주를 분리하였다. Cam 1040은 탄소원으로 각각 200$\mu\textrm{g}$/$m\ell$의 m-toluate, benzoate, camphor 및 phenol이 혼합 첨가된 배지에서 진탕배양했을 때 균체증식에 비례적으로 COD 감소를 나타내었고 첨가 탄소원은 camphor, phenol, benzoate, m-toluate 순서로 분해 이용하였다. Cam 1040 균주는 약 98kb로 추정된 camphor 자화능과 관련된 plasmid를 보유하고 있음을 확인하였다. 또한 Cam 1040 균주에 NAH 2를 도입, salicylate와naphthalene 자화능을 가하므로서 더욱 다양한 기질 분해능을 가진 Cam 1043균주를 얻었다.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 1991년도 추계학술발표회 논문집 지반공학에서의 컴퓨터 활용 COMPUTER UTILIZATION IN GEOTECHNICAL ENGINEERING
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• pp.362-375
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• 1991

Background and Necessity of the study : For more than 20 years, the soil engineering reserach group of Chonnam National University has been performing the deformation analysis of soft clayey foundation, since the University is located near the south-western coast of Korean Peninsulla, along which tide reclamation works have been under proaressing. Associsted with the fact mentioned above, the researchers have been developing a computer program in order to carry out deformation analysis of soft foundation since early 1980. Case-studies : In this research, the Biot's equation was selected as the governing equation coupled with several constitutive models including original and modified Cam-clay models, elasto-viscoplastic model, Lade's model etc. The anisotropy of soi1 can be considered in this program. To validate the accuracy of the computer program developed a couple of case-studies were performed. These include the pilot banking, sand drain considering smear effect and compound foundation reinforced with sheet pile into soft foundation.i) The pilot banking Good results could be acquired by assuming banking load as the body force composed of finite element mesh rather than equivalent concentrated load.ii) The sand drain Due to smear, the delay of consolidation was remarkable at the early stsge. so safety for the failure of foundation should be checked for the initial step of consolidation. iii) The compound foundation Accurate results were obtained by introducing the joint element method for the soft foundation reinforced with sheet pile into soiㅣ.

• 한국자동차공학회논문집
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• 제2권5호
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• pp.74-84
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• 1994

This paper discusses a method to generate the tool path for NC machining of automobile panel dies. The source data representing a panel die may be generated from digitizing machines, other CAD/CAM systems via IGES files, of compound surface models. From the source data, three types of interferencefree tool paths are generated automatically ; a parallel (Cartesian), an isometric, and a pencil cutting tool path. For the interference-free tool path, a polyhedral model composed of several triangles, and an 'offset triangle' approach are exploited. Finally, some practical examples are illustrated.

• 한국생산제조학회지
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• 제8권6호
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• pp.105-112
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• 1999

In this paper we deal with tool interference problem in the case of compound surface machining. A new tool interference detection and correction method based on the envelope of the tool path is suggested to identify and correct the tool interference - not only within the local path of tool movement, but also outside of the tool path. Therefore, the developed strategy can be used to check the possible interference in any region of the surface. In order to analyze quantitatively the milled surface error produced by the tool interference, improved surface prediction model is also suggested in cutting process by general cutters. The effectiveness of the proposed method is demonstrated through simulation study.

• Biomolecules & Therapeutics
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• 제17권4호
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• pp.422-429
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• 2009

Invasion and metastasis is the main cause of cancer mortality. Angiogenesis is a prerequisite for the tumor growth and metastasis. Matrix metalloproteinases (MMPs) are the key enzymes playing in the invasive growth and metastasis of cancer as well as angiogenesis. Xanthohumol, a prenylated chalcone of the Hop plant (Humulus lupulus L), has been reported to suppress cancer invasion and angiogenesis. In the present study, we investigated the antiinvasive effects of xanthohumol (1) and its synthetic derivatives, 4'-O-methylxanthohumol SEM ether (2), xanthohumol C (3), and xanthohumol C MOM ether (4) in relation to MMP expression in HT-1080 human fibrosarcoma cells. The compound 1 and its derivative, 3 and 4, significantly inhibited serum-induced HT-1080 cell invasion, and 12-O-tetradecanoylphorbol-13-acetate (TPA)-enhanced activity and expression level of MMP-2 and MMP-9 in a concentration-dependant manner. In addition, they inhibited TPA-enhanced expression of MT1-MMP with relatively weak inhibition in tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 level. The compound 1 significantly decreased the cell viability, whereas the derivatives, 2 and 3 showed no cytotoxicity, and compound 4 showed slight cytotoxicity in the cells. Furthermore, in a chick chorioallantoic membrane (CAM) assay, the derivatives 3 and 4 dose-dependently suppressed vascular endothelial growth factor (VEGF)-induced angiogenesis, which is similar to that of compound 1. Taken together, the results indicate that compounds 3 and 4 may be valuable anti-angiogenic agents in the treatment of chronic diseases such as cancer and inflammation working through suppression of MMP-2 and MMP-9.