• Title/Summary/Keyword: Compound risk

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Impact Assessment of Sea_Level Rise based on Coastal Vulnerability Index (연안 취약성 지수를 활용한 해수면 상승 영향평가 방안 연구)

  • Lee, Haemi;Kang, Tae soon;Cho, Kwangwoo
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.27 no.5
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    • pp.304-314
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    • 2015
  • We have reviewed the current status of coastal vulnerability index(CVI) to be guided into an appropriate CVI development for Korean coast and applied a methodology into the east coast of Korea to quantify coastal vulnerability by future sea_level rise. The CVIs reviewed includes USGS CVI, sea_level rise CVI, compound CVI, and multi scale CVI. The USGS CVI, expressed into the external forcing of sea_level rise, wave and tide, and adaptive capacity of morphology, erosion and slope, is adopted here for CVI quantification. The range of CVI is 1.826~22.361 with a mean of 7.085 for present condition and increases into 2.887~30.619 with a mean of 12.361 for the year of 2100(1 m sea_level rise). The index "VERY HIGH" is currently 8.57% of the coast and occupies 35.56% in 2100. The pattern of CVI change by sea_level rise is different to different local areas, and Gangneung, Yangyang and Goseong show the highest increase. The land use pattern in the "VERY HIGH" index is dominated by both human system of housing complex, road, cropland, etc, and natural system of sand, wetland, forestry, etc., which suggests existing land utilization should be reframed in the era of climate change. Though CVI approach is highly efficient to deal with a large set of climate scenarios entailed in climate impact assessment due to uncertainties, we also propose three_level assessment for the application of CVI methodology in the site specific adaptation such as first screening assessment by CVI, second scoping assessment by impact model, and final risk quantification with the result of impact model.

A Study on the Non-Toxic Compound-based Multi-layered Radiation Shielding Sheet and Improvement of Properties (무독성 화합물 기반의 다층 구조 방사선 차폐 시트 개발과 특성 개선에 관한 연구)

  • Heo, Ye Ji;Yang, Seung u;Park, Ji Koon
    • Journal of the Korean Society of Radiology
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    • v.14 no.2
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    • pp.149-155
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    • 2020
  • Most of radiation protection clothing is made of lead with excellent radiation shielding because it has excellent process ability and economic efficiency and has a high atomic number. However, lead is classified as a hazardous heavy metal, and there is a risk of lead poisoning. Recently, research to replace lead has been actively conducted. In this study, a research on a shielding sheet with improved physical properties while maintaining the radiation shielding ability equivalent to that of conventional materials by mixing two materials that are harmless to the human body, such as BaSO4 and Bi2O3, and a silicone material binder Was performed. For comparison evaluation with the existing lead shielding sheet, the shielding rate was evaluated using a 40 degree shielding sheet having the highest porosity. As a result, it was analyzed that the shielding rate was superior to 9 % or more at the same thickness. In addition, as a result of studies to improve the physical properties of the shielding sheet, it was analyzed that the shielding sheet mixed with BaSO4/nylon/Bi2O3 was the best.

Suppression of the Expression of Cyclooxygenase-2 Induced by Toll-like Receptor 2, 3, and 4 Agonists by 6-Shogaol (6-Shogaol의 Toll-like receptor 2, 3, 4 agonists에 의해서 유도된 cyclooxygenase-2 발현 억제)

  • Kim, Jeom-Ji;An, Sang-Il;Lee, Jeon-Su;Yun, Sae-Mi;Lee, Mi-Yeong;Yun, Hyeong-Seon
    • Korean Journal of Food Science and Technology
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    • v.40 no.3
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    • pp.332-336
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    • 2008
  • Ginger is widely used as a traditional herbal medicine. Both ginger and its extracts have been used to treat many chronic inflammatory conditions via the inhibition of nuclear factor-kappa B (NF-${\kappa}B$) activation, which results in the suppression of cyclooxygenase-2 (COX-2) expression. However, the mechanisms as to how ginger extracts mediate their health effects are largely unknown. Toll-like receptors (TLRs) trigger anti-microbial innate immune responses, recognizing conserved microbial structural molecules that are known as pathogen-associated molecular patterns. All TLR signaling pathways culminate in the activation of NF-${\kappa}B$. The activation of NF- ${\kappa}B$ leads to the induction of inflammatory gene products, including cytokines and COX-2. This study reports the biochemical evidence that 6-shogaol, an active compound in ginger, inhibits NF-${\kappa}B$ activation and COX-2 expression induced by TLR2, TLR3, and TLR4 agonists. Furthermore, 6-shogaol inhibited NF-${\kappa}B$ activation induced by the following downstream signaling components of the TLRs: MyD88, $IKK{\beta}$, and p65. These results imply that ginger can modulate immune responses that could potentially modify the risk of many chronic inflammatory diseases.

Estimation of Benzene Emissions from Mobile Sources in Korea (국내 이동오염원에서 발생되는 벤젠 배출량 산정)

  • Lee, Ju-Hyoung;Cha, Jun-Seok;Hong, Ji-Hyung;Jung, Dong-Il;Kim, Ji-Young
    • Journal of Korean Society for Atmospheric Environment
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    • v.24 no.1
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    • pp.72-82
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    • 2008
  • Benzene is a very harmful and toxic compound known as human carcinogen by all routes of exposure. Owing to the risky feature of benzene, several countries such as Japan, UK and EU have established the ambient air quality standard and protect from that risk of it. Korea also has designated it as one of the criteria air pollutants and established the concentration limit ($5\;{\mu}g/m^3$) in the air and is going to apply the standard from 2010. Benzene is emitted from various sources such as combustion plants, production processes, waste treatment facilities and also automobiles. Mobile source is known as one of the major emission sources of benzene. In this study, we estimated the domestic emissions of benzene from mobile source and compared the results with those of advanced countries. Mobile source was divided into 2 categories, Le., on-road source and non-road source. The total emissions of benzene from mobile source were estimated as 3,106 tons/yr and 1,612 tons/yr was emitted from on-road source and 1,494 tons/yr was from non-road source. Emission ratio of benzene from on-road source showed that 80.0% was from passenger cars, 10.1% was from taxis, 7.2% was from light-duty vehicles, 2.5% was from heavy-duty vehicles and 0.2% was from buses. In the case of non-road source, the distribution showed that 66.3% was from construction machineries, 14.5% was from locomotives, 11.7% was from ships, 7.1% was from agriculture equipments and 0.5% was from aircrafts. The cold-start emissions were estimated as 942 tons/yr and this value was almost 1.5 times greater than that for hot engine emissions (608 tons/yr). In addition, the fuel-based distribution was 65.9%, 31.1% and 2.8% from gasoline, LPG and diesel vehicles, respectively. The emission ratio from mobile source occupied 65% and 30% of total benzene emissions in USA and UK, respectively. In case of Korea, the emission ratio of benzene from mobile source occupied 29% (15% from on-road source, 14% from non-road source) which showed similar value with UK.

Correlation of Korean Elderly Dental Health Capacity and Preferred Foods (한국 노인의 치아건강도와 선호식품과의 관련성)

  • Ju, On-Ju;Kim, In-Ja
    • Journal of dental hygiene science
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    • v.15 no.6
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    • pp.712-720
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    • 2015
  • The purpose of this study is to examine whether any correlation exists between the dental health capacity and preferred foods of Korean senior citizens over the age of 65 years. The 5th Korean National Health and Nutrition Survey were used. Tissue health index (T-health), Sound teeth (ST), Functioning teeth index (FS-T), Present teeth (PT), and Missing teeth (MT) were used as variables to assess the dental health capacity of the elderly. Preferred foods of the elderly included 63 foods that were categorized as cereals, pulses and roots, meat and poultry, fish, vegetables, sea algae, fruits, milk and dairy products, cream and sugar, and other foods. For data analysis, the weighted average was taken into consideration to generate planning files, and then complex sample analysis were conducted. For statistical analysis, frequency analysis, t-test, one-way ANOVA, and compound specimen linear regression analysis were conducted. T-health score was significantly high in the group with high preference for cereals, fruits, and other foods. In terms of age and economic status, 65~69 years, 70~74 years, and mid to low range in the income ranges scored high in T-health. ST score was significant in the group that preferred cereals, other foods; the corresponding demographic profiles represent 65~69 years, 70~74 years, and the mid-range income communities. FS-T was significant in relation with a preference for fruits, creams and sugars, other foods; the scores were also high for 65~69 years, 70~74 years, and mid-low to low income groups. PT and MT were significant in the group that preferred cereals and fruits; the same applied for 65~69 years, 70~74 years, and mid-low to low income individuals (p<0.05). Food preferences seemed to vary depending on the dental health state of the elderly, and the dental health state of the elderly may act as a risk factor for nutritional imbalance.

Study on Economic and Financial Education for the North Koreans after Unification: from the Perspective of Behavioral Economics (통일 후 북한 주민 대상 경제금융 교육에 관한 연구: 행태경제학 관점을 중심으로)

  • Son, Jeong-Kook;Kim, Young-Min
    • The Journal of the Convergence on Culture Technology
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    • v.7 no.2
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    • pp.239-246
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    • 2021
  • Unification means the change of the economic system from 'Planned Economy' of the North Korea to 'Market Economy' of the South Korea. Therefore, it may cause confusions and difficulties for North Koreans who have been under planned economy for ages. So, we need to take the perspective of behavioral economics for the effective education. First of all, it is about overall finance, which contains the record of financial transactions, effect of inflation, investors' bounded rationality, and choice difficulty of financial products. Second, it is about borrowings, which includes the credit management, interest rate of difference among financial institutions. Third, it is about investment on financial products, which includes the effect of cost on returns, difference between compound interest and simple interest, trade-off between expected return and risk, market and non-market risks, the importance of diversification, and passive & aggressive investments.

Association of ionized magnesium, total magnesium, gestational age, and intraventricular hemorrhage in preterm babies (미숙아에서 이온화 마그네슘, 총 마그네슘과 재태 연령과의 관계 및 뇌실 내 출혈과의 관계)

  • Kim, Tae-Yeon;Lee, Hyun-Hee;Sung, Tae-Jung
    • Clinical and Experimental Pediatrics
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    • v.52 no.10
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    • pp.1140-1146
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    • 2009
  • Purpose:The pathophysiology of magnesium, the second highest common compound in humans, is still unclear, especially in preterm babies. We accessed the association between total magnesium (tMg), ionized Mg (iMg), and gestational age (GA) and that between serum magnesium (sMg) and intraventricular hemorrhage (IVH) in preterm babies. Methods:In all, 119 inborn preterm infants admitted between July 2006 and February 2008 were divided into the IVH group (19) and the control group (100) and were prospectively analyzed. TMg, iMg, pH, total calcium (tCa), and ionized Ca (iCa) levels were determined immediately after delivery or within 3 hours after birth, and their correlation with GA were investigated. Results:TMg was not correlated with GA, tCa, iCa, and pH. IMg was correlated with tMg (r=0.288, P=0.002) and iCa (r=0.212, P=0.021); however, it was not correlated with GA and pH. Mean GA and birth weight were significantly lower (P=0.002) and smaller (P=0.030) in the IVH group. Mean sMg was higher in the IVH group ($2.5{\pm}0.9mg/dL$) than in the control group ($2.1{\pm}0.6mg/dL$) (P=0.021). SMg was a risk factor even after logistic regression analysis (OR, 2.798; 95% C.I., 1.265-6.192; P=0.011). Conclusion:In less than 37-week-old preterm babies, tMg and iMg were similar, regardless of GA. High sMg may be a risk factor for IVH in premature babies, regardless of their exposure to antenatal magnesium.

tans-Resveratrol Content of Varieties and Growth Period in Peanut (땅콩 품종 및 생육기별 trans-Resveratrol 함량)

  • Lee, Mi-Ja;Cheong, Young-Keun;Kim, Hyung-Soon;Park, Ki-Hun;Doo, Hong-Soo;Suh, Duck-Yong
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.48 no.6
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    • pp.429-433
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    • 2003
  • trans-Resveratrol(3,5,4'-trihydroxystilbene) is phenolic compound present in grapes, wines, and peanuts, has been reported to have health benefits including anticarcinogenic effects, protection against cardiovascular diseases and reduced cancer risk. A simple method for the quantitative extraction of trans-resveratrol from peanut has been developed. Optimal conditions for extraction were investigated. Type of solvent, time, and temperature assayed influenced trans-resveratrol yield. Adequate extraction condition was decided to ethanol/water (80:20v/v) maintained at $25^{\circ}C$ for 45 min. After extraction, the protocol consists of sample preparation using a $\textrm{C}_{18}$ solid-phase extraction (SPE) cartridge after concentrate with rotary evaporator and quantified by reversed phase HPLC using a $\textrm{C}_{18}$ column at 308 nm. Analytical methods for measuring trans-resveratrol in peanut were adapted to isolate, identify, and quantify trans-resveratrol in 11 peanut varieties by HPLC (high-performance liquid chromatography) with UV detector, The 11 peanut varieties content ranged from 0.018 to 1.125 $\mu\textrm{g}/\textrm{g}$ with an average of 0.289 $\mu\textrm{g}/\textrm{g}$. The contents were higher in the seeds with than without testa, regardless of varieties. The trans-resveratrol content was Higher in 110, 130 days after sowing than that of other period.

Antigenotoxic and Anticarcinogenic Effects of Styela plicata (오만둥이(Styela plicata)의 항유전독성 및 대장암 억제효과에 관한 연구)

  • Seo, Bo-Young;Kim, Jung-Mi;Lee, Seung-Cheol;Park, Eun-Ju
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.38 no.7
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    • pp.839-845
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    • 2009
  • Colorectal cancer is the third most common malignant neoplasm in the world. Much attention has been focused on reducing colon cancer risk through medical properties of natural compound that could act as anticarcinogens. In this study, we evaluated the antioxidant and antigenotoxic effects of Styela plicata (S. plicata) from in vitro experiments. S. plicata extracts showed antioxidant activity measured by TRAP assay and antigenotoxic effect in $200{\mu}M$ $H_2O_2$ induced DNA damage in human leukocytes. Especially, freeze-dried S. plicata extracted with methanol showed the highest level of TRAP (0.225 mM) and inhibition of DNA damage (66.8%). Additionally we observed the effect of S. plicata on the formation of aberrant crypt foci (ACF) induced by dimethylhydrazine (DMH) and DMH induced DNA damage (by comet assay) in male SD rats. The animals were divided into three groups and fed high-fat and low fiber diet (100 g lard+20 g cellulose/kg diet) without (normal control and DMH control) or with a 3% (w/w) of lyophilized S. plicata powder (DMH+S. plicata). One week after beginning the diets, rats were treated with DMH (30 mg/kg, s.c.) for 6 weeks except for normal control group, which was treated saline instead; dietary treatments were continued for the entire experiment. Nine weeks after DMH injection, administration of S. plicata resulted in reduction of ACF numbers, to 82.7% of the carcinogen control value ($7.67{\pm}2.04$ vs. $1.33{\pm}0.53$: p<0.01). S. plicata supplementation induced antigenotoxic effect on DMH-induced DNA damage in the blood cell (% tail intensity: $6.79{\pm}0.26$ vs. $6.13{\pm}0.22$). These data indicate that S. plicata extract has antigenotoxic and anticarcinogenic effects from in vitro experiments and S. plicata exerts a protective effect on the process of colon carcinogenesis, possibly by suppressing the DMH-induced DNA damage in blood cell and the development of preneoplastic lesions in colon.

Biodiversity Conservation and the Yellow Sea Large Marine Ecosystem Project (생물다양성 보전과 황해 광역 해양생태계 관리계획)

  • Walton, Mark
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.13 no.4
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    • pp.335-340
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    • 2010
  • The paper describes the objectives of Yellow Sea Large Marine Ecosystem (YSLME) project, focusing on procedural and practical aspects. YSLME is a highly productive sea yet possibly one of the most impacted large marine ecosystems, in terms of anthropogenic stressors, due the enormous coastal population. The aim of the YSLME project is the reduction of ecosystem stress through identification of the environmental problems in the Transboundary Diagnostic Analysis (TDA) that are then addressed in the Strategic Action Programme (SAP). One of the major problems found to be affecting biological diversity is habitat modification through wetland reclamation, conversion and degradation. Since the early 1900's more than 40% of intertidal wetlands have been reclaimed in Korea, and 60% of Chinese coastal wetlands have been converted or reclaimed. Damaging fishing practices, pollution and coastal eutrophication have further degraded the coastal environment reducing the biological diversity. To combat this loss, the YSLME project has mounted a public awareness campaign to raise environmental consciousness targeted at all different levels of society, from politicians at parliamentary workshops, local government officer training events, scientific conferences and involvement of scientists in the project research and reporting, to university and high school students in our visiting internship programmes and environmental camps. We have also built networks through the Yellow Sea Partnership and by liaising and working with other environmental organizations and NGOs. NGO's are recognised as important partners in the environmental conservation as they already have extensive local networks that can be lacking in international organisations. Effective links have been built with many of these NGOs through the small grants programme. Working with WWF's YSESP project and other academic and research institutions we have conducted our own biodiversity assessments that have contributed to the science-based development of the SAP for the YSLME. Our regional targets for biodiversity outlined in the SAP include: Improvements in the densities, distributions and genetic diversity of current populations of all living organisms including endangered and endemic species; Maintenance of habitats according to standards and regulations of 2007; and a reduction in the risk of introduced species. Endorsement of the SAP and its successful implementation, during the proposed second phase of the YSLEM project, will ensure that biological diversity is here to benefit future generations.