• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.23 no.2
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• pp.132-138
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• 2011

In the present article, we investigate numerically turbulent flow of air through compound rectangular channels. Large eddy simulation(LES) is employed for unsteady turbulence modeling. LES gives better predictions for the axial mean velocity distribution than those of other turbulent models. Strong large-scale quasi-periodic flow oscillations are observed in most of the geometries investigated. Such large-scale flow oscillations in compound rectangular channels are similar to the quasi-periodic flow pulsation through the gaps between fuel rod bundle in nuclear reactor. It exists in any longitudinal connecting gap between two flow channels. The frequency of this flow oscillation is determined by the geometry of the gap. The large scale cross motions through the rectangular compound channels induce significant heat transfer enhancement of the compound channel flow.

• Journal of Communications and Networks
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• v.12 no.5
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• pp.411-432
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• 2010

We consider three different secure broadcasting scenarios: i) Broadcast channels with common and confidential messages (BCC), ii) multi-receiver wiretap channels with public and confidential messages, and iii) compound wiretap channels. The BCC is a broadcast channel with two users, where in addition to the common message sent to both users, a private message, which needs to be kept hidden as much as possible from the other user, is sent to each user. In this model, each user treats the other user as an eavesdropper. The multi-receiver wiretap channel is a broadcast channel with two legitimate users and an external eavesdropper, where the transmitter sends a pair of public and confidential messages to each legitimate user. Although there is no secrecy concern about the public messages, the confidential messages need to be kept perfectly secret from the eavesdropper. The compound wiretap channel is a compound broadcast channel with a group of legitimate users and a group of eavesdroppers. In this model, the transmitter sends a common confidential message to the legitimate users, and this confidential message needs to be kept perfectly secret from all eavesdroppers. In this paper, we provide a survey of the existing information-theoretic results for these three forms of secure broadcasting problems, with a closer look at the Gaussian multiple-input multiple-output (MIMO) channel models. We also present the existing results for the more general discrete memoryless channel models, as they are often the first step in obtaining the capacity results for the corresponding Gaussian MIMO channel models.

• Proceedings of the Korean Biophysical Society Conference
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• 2003.06a
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• pp.42-42
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• 2003

Large-conductance $Ca^{2+}$-activated potassium channels ($BK_{Ca}$ are a widely distributed and play key roles in various cell functions. In nerve cells, $BK_{Ca}$ channels shorten the duration of action potentials and block $Ca^{2+}$ entry thereby repolarizing excitable cells after excitation. $BK_{Ca}$ channel opening has been postulated to confer neuroprotection during stroke, and has attracted attention as a means for therapeutic intervention in asthma, hypertension, convulsions, and traumatic brain injury. Several natural and synthetic compounds including a steroid hormone, $\beta$-estradiol, have been identified as the activators of $BK_{Ca}$ channels. Based on the structural features of the previously reported activators of $BK_{Ca}$ channels, we designed several lead compounds, synthesized chemically, and tested their functional activity on cloned $BK_{Ca}$ channels. The $\alpha$ subunit of rat $BK_{Ca}$ channel was expressed alone or with different $\beta$ subunits in Xenopus oocytes and the effects of the compounds were tested electrophysiological means. One of the lead compounds affected the activity of the $\alpha$ subunit of $BK_{Ca}$ channel in a $\beta$ subunit-specific manner. While the activity of B $K_{ca}$ channel $\alpha$ subunit was Potentiated, the channel composed of $\alpha$ and $\beta$1 subunits were inhibited by this compound. We are currently investigating the mechanism of the $\beta$ subunit-dependent effects and planning to localize the receptor site of the lead compound.f the lead compound.

• Proceedings of the Ginseng society Conference
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• 2006.05a
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• pp.69-70
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• 2006

Purpose: Panaxadiols are more potent than panaxatriols as far as insulin secretory activity is concerned. In this study, we examined insulin secretory activity and mechanism of compound K (CK), a major intestinal bacterial metabolite of ginsenosides. Method: Insulin secretory activity of CK was examined using pancreatic beta cells and in Oral Glucose Tolerance Test assay. In addition, insulin secretory mechanism was studied in terms of calcium dependent or independent pathways. Results: In vitro, CK enhanced the insulin secretion concentration-dependently when compared to glucose-stimulated control cells. Insulin secretory mechanism of CK seems to block ATP sensitive K channels, which was confirmed by diazoxide (K channel opener) but, insulin resistance ameliorating activity of CK can't be ruled out. In vivo, CK showed hypoglycemic effect in OGTT.

• Ecology and Resilient Infrastructure
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• v.4 no.4
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• pp.207-215
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• 2017

Hydraulic issues such as flow resistance, side wall correction, sediment, erosion and deposition, and channel design have close relation with distribution of bed shear stresses but the measurement of the distribution of bed shear stresses is not easy. In this study the Preston tube which makes possible relatively simple measurement of bed shear stresses is used to analyze the characteristics of bed shear distribution in compound open channels with different depth ratio. The Preston tubes are made and calibrated to develop the calibration formula and then they are applied to measure bed shear stress distribution in 5 cases depth ratio condition of compound channels. The results are compared with former experiment data, and characteristics of bed shear stress distributions are studied with different channel scales and Reynolds numbers. Although bed shear distributions with depth ratio show overall agreement with former studies, some differences are verified in bed shear variation, formation of inflection point in main channel, and distribution near floodplain junction which are due to high Reynolds number. Through the study applicability of the Preston tubes are also verified and characteristics of bed shear distribution in compound channels are suggested with Reynolds number and depth ratio.

• Proceedings of the Korea Water Resources Association Conference
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• 2005.09b
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• pp.1168-1169
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• 2005

• Ecology and Resilient Infrastructure
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• v.5 no.4
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• pp.199-209
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• 2018

In river design, consideration of bed shear stresses is necessary to secure stability of levee and floodplain. In this study distributions of bed shear stresses in compound open channels are analyzed through numerical simulation for various width and depth. LES solver in OpenFOAM is applied to 12 cases of compound channel shapes considering secondary flow which effects distributions of bed shear stresses. By the results time averaged velocity distributions, secondary currents, and distributions of bed shear stresses are analyzed. Overall distributions of bed shears in floodplain show that higher shear stresses are seen in left of floodplain and the shears decrease toward right of floodplain. However, high local variations in shear stresses are shown due to the secondary flow effects. In shallow floodplain, bed shear stresses show low value below 0.8 times of averaged bed shear. In deep floodplain, bed shear stresses show high value over 1.2 - 1.4 times of averaged bed shear.

• Proceedings of the Korea Water Resources Association Conference
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• 2005.09a
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• pp.360-361
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• 2005

• Proceedings of the Korea Water Resources Association Conference
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• 2005.09a
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• pp.202-203
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• 2005

• Proceedings of the Korea Water Resources Association Conference
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• 1995.05a
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• pp.355-360
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• 1995