• Title/Summary/Keyword: Compound Ⅲ

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The Effects of Dried Orange Peel Compound intaking and Exercise Training on the Physique, Body Fat, and Concentration of Blood Lipid in Obese Women (진피 복합제 복용과 운동이 비만 여성의 체격, 체지방 및 혈중지질에 미치는 영향)

  • Lee, Kyu-Moon;Kim, Hyeon-Ju;Kim, Seung-Hwan;Kim, Hack-Seang;Ro, Jai-Seup;Oh, Ki-Wan;Lee, Kyong-Soon;Choi, Jong-Hwan
    • Korean Journal of Pharmacognosy
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    • v.33 no.1 s.128
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    • pp.57-63
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    • 2002
  • The purpose of this research was to investigate the effects of dried orange peel compound intaking and exercise training on the physique, body fat, and concentration bloodlipid in obese women. Ninety-seven volunteers(mean age 21.47 ${\pm}$ 1.47 yrs), all over 30% of body fat, agreed to Participate and were placed in 4 groups: dried orange peel compound intaking and exercise group(n=25), only exercise group(n=25), only dried orange peel compound intaking group(n=24), and control group(n=20). The subjects who joined this project were asked to take dried orange peel compound(2 times/day, 30 ml/time) or participate in exercise program(3 times/week, 70 min/day), depending on particular group for 12 weeks. They were tested on their height, weight, circumference of chest, abdomen, hip, and thigh, body fat%, total-cholesterol(TC), HDL-C, LDL-c, and triglyceride(TG) at the beginning and the end of the 12-weeks program. For data analysis, paired t-tests and ANCOVAs were used. The intaking of dried orange peel compound was influenced on weight, circumference of chest, abdomen, hip, and thigh, body fat%, HDL-C, LDL-C, and TG. The exercise participation had almost same effects on those dependent variables. Furthermore, the dried orange peel compound intaking along with exercise training was the most effective on those dependent variables among them. Therefore, these results indicate that dried orange peel compound intaking, like exercise, may be useful for controling weight, body fat, HDL-C, LDL-C, and TG.

Effects of Applied of Organic-Compound Fertilizer on the Weed Control and Rice Growth Condition in the Transplanting Rice Cultivation (벼 이앙재배에서 유기질 복합비료 시용이 잡초억제와 벼 생육환경에 미치는 영향)

  • An, Xue-Hua;Zhao, Xue-Ping;Lee, Sang-Bok;Im, Il-Bin;An, Wen-Hao
    • Korean Journal of Weed Science
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    • v.30 no.3
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    • pp.258-265
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    • 2010
  • The effects of organic-compound fertilizer on weed control and rice growth in the transplanting rice cultivation were researched in this article. The results showed that the growth of transplanted rice was promoted (the increased rate was 10.3~27.2%), but the plant number for Echinochloa crus-galli was controlled (the inhibition rate was 50.3~89.2%), besides, small amount of organic-compound fertilizer in controlling Aneilema keisak was highly effective when the transplanted rice was treated with 125~250 kg $10a^{-1}$ organic-compound fertilizer. Moreover, E. crus-galli, Monochoria vaginalis and A. keisak were inhibited largely by increasing the water depth (1~5 cm), whereas Eleocharis kuroguwai and other sedges weeds were not effected by water depth. Compared with the temperature of $20{\sim}35^{\circ}C$, the plant occurrence of E. crus-galli and M. vaginalis at high temperature was inhibited (the inhibition rate were 75.4~92.2% and 49.5%~81.6%, respectively). When the transplanted rice was treated with the above organic-compound fertilizer after 10day, the inhibition rate of plant occurrence for E. crus-galli and M. vaginalis was 33.7% and 23.3%, respectively. Similarly, in the later period of rice growth, the plant height and the numbers of tiller grew slowly in conventional soil in comparison with the soil treated with organic-compound fertilizer. It has been found that the rice yield in experimental soil was decreased by 4%. This result in the field experiment showed that organic material contents in conventional soil were lower than that in soil which used the organic-compound fertilizer. Weed control in experimental soil showed 60.5% lower effects than that in conventional soil.

Inhibitory Effects of Flavonoids Isolated from the Leaves of Stewartia koreana on Nitric-oxide Production in LPS-stimulated RAW 264.7 Cells (노각나무 잎에서 분리된 플라보노이드에 의한 대식세포에서 산화질소 생성 억제효과)

  • Lee, Seung-Su;Bang, Myun-Ho;Park, Se-Ho;Chung, Dae-kyun;Yang, Seun-Ah
    • Journal of Life Science
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    • v.28 no.5
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    • pp.509-516
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    • 2018
  • Five phenolic compounds were isolated from the ethyl acetate fraction of leaves from Stewartia koreana, and their nitric-oxide (NO) inhibitory activities were measured to identify the major active constituents responsible for the efficacy of the extract against inflammatory reactions. These five compounds were quercetin (1), quercitrin (2), hyperin (3), quercetin-3-O-(6"-O-galloyl)-${\beta}$-D-galactopyranoside (4), and kaempferol 3-O-[2",6"-di-O-(trans-p-coumaroyl)]-${\beta}$-D-glucopyranoside (5). Among the separated compounds in the EtOAc fraction, compounds 4 and 5 were isolated for the first time, and no study has yet reported their anti-inflammatory effects. The compounds were identified by spectroscopic analysis, and the isolated compounds showed significant NO inhibitory effects in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. Compound 5 showed the most potent inhibitory effect (63.35% inhibition) against LPS-induced NO production compared to that of compound 1 (17.17%), compound 2 (5.0%), compound 3 (3.92%), and compound 4 (6.32%) at $10{\mu}g/ml$ concentration. NO production was inhibited by suppressing the protein expression of inducible nitric-oxide synthase in LPS-stimulated RAW 264.7 macrophages. These results indicate that kaempferol 3-O-[2",6"-di-O-(trans-p-coumaroyl)]-${\beta}$-D-glucopyranoside might be the major active compound responsible for the anti-inflammatory effects of S. koreana.

Inhibitory Effects of Ginseng Extracts on Histamine-release from Rat's Mast Cell (인삼추출물의 랫트 비만세포 히스타민 유리 억제 효과)

  • Park, Kwang-Hyun;Kim, Young-Seon;Jeong, Jae-Hun
    • Korean Journal of Plant Resources
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    • v.24 no.1
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    • pp.98-104
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    • 2011
  • We investigated inhibitory effects of ginseng extracts against compound 48/80-induced responses in rat peritoneal mast cells. Initially, we optimized extraction condition with various temperature and time for recovery of high saponin contents in extracts. Using a primary rat peritoneal mast cells, we examined whether ginseng extracts inhibit compound 48/80-induced histamine release form rat mast cells. High red ginseng-spercific saponin containing extracts were recovered at $85^{\circ}C$ for 48 hr, and had no cytotoxicity with relatively high dose of extracts on rat peritoneal mast cells(<0.5 mg/ml). For examine of ameliorate effects of mast cells responses by ginseng extract, we pre-treated the extracts or saline to mast cells and treated compound 48/80. In results, compound 48/80 treatment was increased histamine release (approximately 30%) from mast cells than normal group, whereas ginseng treatment was completely inhibited histamine release. These results suggested that ginseng extracts inhibits the compound 48/80-induced mast cell activation, and ginseng extracts is a candidate for effective therapeutic tools of allergic diseases.

Thermo-mechanical Behavior of WB-PBGA Packages Considering Viscoelastic Material Properties (점탄성 물성치를 고려한 WB-PBGA 패키지의 열-기계적 변형 거동)

  • Kim, Man-Ki;Joo, Jin-Won
    • Journal of the Microelectronics and Packaging Society
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    • v.19 no.2
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    • pp.17-28
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    • 2012
  • It is known that thermo-mechanical properties of solder material and molding compound in WB-PBGA packages are considerably affected by not only temperature but elapsed time. In this paper, finite element analysis (FEA) taking material nonlinearity into account was performed for more reliable prediction on deformation behavior of a lead-free WB-PBGA package, and the results were compared with experimental results from moire interferometry. Prior to FEA on the WB-PBGA package, it was carried out for two material layers consisting of molding compound and substrate in terms of temperature and time-dependent viscoelastic effects of molding compound. Reliable deformation analysis for temperature change was then accomplished using viscoplastic properties for solder ball and viscoelastic properties for molding compound, and the analysis was also verified with experimental results. The result showed that the deformation of WB-PBGA packages was strongly dependent on material model of molding compound; thus, temperature and time-dependent viscoelastic behavior must be considered for the molding compound analysis. In addition, viscoelastic properties of B-type molding compound having comparatively high glass transition temperature of $135^{\circ}C$ could be recommended for reliable prediction on deformation of SAC lead-free WB-PBGA packages.

Environmental Adaptability of Eupatorium rugosum : Relationship between Accumulation of Heavy Metals and Phenolic Compounds (서양등골나물의 환경적응력 : 중금속 축적과 Phenolic Compounds의 관계)

  • 김용옥;박종야;이호준
    • The Korean Journal of Ecology
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    • v.26 no.1
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    • pp.5-12
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    • 2003
  • Seed germination rate and seedling growth were measured on 6 different species(Phytolacca americana, Eupatorium rugosum, Rumex acetocella, Echinochloa crusgalli, Cassia mimosoides var. nomame, Setaria viridis) treated with leaf extract of E. rugosum. Total phenolic compound and heavy metal were analyzed on leaf and soil with and without E. rugosum. The growth of P. americana seedlings were stimulated by 10% and 25% of E. rugosum water extract treatment. The content of total phenolic compounds in soil was lower than that of leaf extract, and 25% was confirmed as threshold concentration in natural systems because the total phenolic compounds were not significantly different between the control soils and the soil treated with 10%, and 25% extract. Total phenolic compound concentrations of the leaf extracts were highest (1.66 mg/l) with E. rugosum grown under the Quercus forest canopy and lowest (1.09 mg/l) for the plant grown in the mixed forest edge. Leaf extracts of plants selected in different sampling sites (Forest interior, Forest edge, under Pinus Canopy and Quercus Canopy) were significant, while soil extracts were not. Seed germination of R. acetocella and S. viridis were significantly inhibited at over 50% concentrations of E. rugosum, but C. mimosoides var. nomame was not affected at any concentration. The radicle and shoot growth of the native species group were reduced two times more than those of the exotic species group by the treatment of extracts. Especially, the seed germination percentage and dry weight of E. rugosum were greater than those of the control group by treatments with extracts of 10% and 25%. Analysis of aqueous extracts from E. rugosum by HPLC identified 6 phenolic compounds: caffeic acid (460.9 mg/l), benzoic acid (109.7 mg/l), protocatechuic acid (7.3 mg/l), ρ-hydroquinone (6.0 mg/l), cinnamic acid (2.7 mg/l) and hydroquinone (0.23 mg/l). The seed germination of P. americana was also inhibited dramatically by protocatechuic acid and cinnamic acid even though the content of caffeic acid (460.9 mg/l) was the highest among analyzed phenolic compounds. The heavy metal content of soil without A. altissima was higher than that of soil with E. rugosum. Particularly, Al, Fe and Mn was considerably high and most of the heavy metal were accumulated in leaves where a high level of total phenolic compounds was found.