• Title/Summary/Keyword: Compound Ⅲ

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Isolation, Purification, and Structural Identification of an Antifungal Compound from a Trichoderma Strain

  • Li, Chong-Wei;Song, Rui-Qing;Yang, Li-Bin;Deng, Xun
    • Journal of Microbiology and Biotechnology
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    • v.25 no.8
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    • pp.1257-1264
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    • 2015
  • Trichoderma strain T-33 has been demonstrated to have inhibitory effect on the fungus species Cytospora chrysosperma. Here, an active antifungal compound was obtained from Trichoderma strain T-33 extract via combined separation technologies, including organic solvent extraction, liquid chromatography, and thin-layer chromatography. The purified compound was further characterized by advanced analytical technologies to elucidate its chemical structure. Results indicated that the active antifungal compound in Trichoderma strain T-33 extract is 2,5-cyclohexadiene-1,4-dione-2,6-bis (1,1-dimethylethyl).

Synthesis and Structural Analysis of a New Layered Cobalt(II) Compound with p-Toluenesulfonic Acid : $[Co(H_2O)_6](CH_3C_6H_4SO_3)_2$ (p-Toluenesulfonate를 가진 새로운 코발트(II) 층상 화합물의 합성과 구조 분석)

  • Kim, Chong-Hyeak;Lee, Sueg-Geun
    • Analytical Science and Technology
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    • v.13 no.4
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    • pp.534-538
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    • 2000
  • The title compound, $[Co(H_2O)_6](CH_3C_6H_4SO_3)_2$, has been prepared and characterized by X-ray crystallography. The crystal structure of the compound demonstrates a layered material constituted by hexaaquacobalt (II) cations and p-toluenesulfonate anions. Geometrical environment of the cobalt atom is octahedrally coordinated by water molecules. The p-toluenesulfonate anions are arranged with the sulfonate groups turned toward opposite side of the layer, alternately. The layered structure is stabilized by the hydrogen bondings between the ligated water molecules and the anionic sulfonate oxygen atoms.

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Development of Polypropylene Fiber Reinforced Environmental Friendly Pavement Material for Farm Road (폴리프로필렌 섬유보강 환경친화형 포장재료의 개발)

  • Sung, Chan-Yong;Kim, Young-Ik
    • Journal of The Korean Society of Agricultural Engineers
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    • v.46 no.1
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    • pp.35-40
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    • 2004
  • This study is performed to examine the physical and mechanical properties of eco-concrete using soil, natural coarse aggregate, excellent soil compound and polypropylene fiber. The test result shows that mass loss ratio is decreased with increasing the content of coarse aggregate and excellent soil compound. The compressive and flexural strengths are increased with increasing the content of coarse aggregate, excellent soil compound and polypropylene fiber. The coefficient of permeability is decreased with increasing the content of coarse aggregate and excellent soil compound, but it is increased in 0.2% polypropylene fiber content. The lowest coefficient of permeability is showed in $5.066\times 10^{-9}$cm/s. These eco-concrete can be used for farm road.

Chemical Properties of the Insecticidal Compound Produced by an Actinomycetes, SS-4993 (방선균 SS-4993이 분비하는 살충물질의 화학적 성상 및 작용기작)

  • 이은정;강경돈;황교열;김두호;이상몽;김신덕;성수일
    • Journal of Sericultural and Entomological Science
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    • v.41 no.3
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    • pp.180-184
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    • 1999
  • The insecticidal compound priduced by Streptomyces SS-4993 strain was indicated to be a relatively stable small compound by pancreatin treatment. The active compound was adsorbed on HP20 and eluted with 70% acetone. Then, the eluate was extracted with ethyl acetate. The content of the extract was determined by thin layer chromatography (Silica gel 60 F254, hexane-ethyl ether-acetic acid,80 : 20 :1). Three active bands (Rf 0.08, 0.07, 0.88) were identified by dermal application using Bombyx mori larvae. Electrophoretic analysis revealed that the injection of strain SS-4993 culture broth into B. mori larvae induce the reduction of the hemolymph proteins level. Especially, the level of apolipophorin-I was decreased drastically.

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Performance Efficiency of Compound CVTs with a 2K-H II (2K-H II 형식 복합형 무단변속기의 효율실험)

  • Park J.M.;Kim Y.S.;Lee S.H.;Choi S.H.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.10a
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    • pp.670-673
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    • 2005
  • We designed the compound CVT (Continuously Variable Transmissions) by combining power circulation mode CVT and power split mode CVT, which have been proposed for connecting 2K-H II differential gear to the V- belt type CVU (Continuously Variable Unit), as an input coupled type. With the designed compound CVT, we carried out theoretical analysis and performance experiments. We proved that the compound CVT had a better performance than either of the power circulation mode or power split mode.

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Identification of Antioxidative Component from Stem Bark of Rhus verniciflua (옻나무 껍질에서 분리한 항산화물질의 성분)

  • Kim, Jung-Bae
    • The Korean Journal of Food And Nutrition
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    • v.16 no.1
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    • pp.60-65
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    • 2003
  • An antioxidant compound was obtained from the water extract of the stem bark from Rhus verniciflua, which has been used in traditional folk remedies. The compound was purified by HPLC, using DEAE, CN and ODS columns. The chemical structure of the compound was identified as gallic acid (3,4,5-hydroxylbenzoic acid) by spectral data including UV, IR, EI (HR)-MS, $^1$H-NMR, $\^$13/C-NMR and elemental analyzer. This compound was found show cytotoxicity against HeLa cell ( IC$\_$50/ : 8.5$\mu\textrm{g}$/$m\ell$).

The Effects of an Additive on the Thermal Properties of a Clathrate Compound (IV) - The Case of TMA Clathrate Compound with Surfactant - (포접화합물의 열물성에 미치는 첨가제의 효과 (IV) - TMA 물계 포접화합물에 계면활성제를 첨가한 경우 -)

  • Chung Nak Kyu;Kim Jin Heung;Kim Chang Oh
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.16 no.12
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    • pp.1212-1217
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    • 2004
  • This study investigated the improvement effect of a small portion of surfactant on the supercooling and the phase change temperature of TMA 30 wt% clathrate compound when surfactant is added to the clathrate compound. The experiments are carried out under various conditions; the concentration of additive ranges between 0.08~0.12 wt% and the temperature of heat source ranges between -8 and -6$^{\circ}C$. The experimental results show that the phase change temperature with the surfactant of 0.1 wt% is lower by 1$^{\circ}C$ than TMA 30 wt% and the supercooling is reduced by 1$0^{\circ}C$.

Antiinflammatory activity of americanin A

  • Lee, Eun-Bang;Lee, Young-Soon;Woo, Won-Sick
    • Archives of Pharmacal Research
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    • v.8 no.3
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    • pp.139-147
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    • 1985
  • Americal A from the seeds of Phytolacca americana, was investigated for the antiinflammatory activity. The compound significantly inhibited edema induction, granuloma formation, arthritis induction and leucocyte emigration in CMC-pouch. But its anticarrageenin activity was not exhibited in adrenalectomized rats. These findings together with decrease in the contents of ascorbic acid and cholesterol in adrenals by administration of the compound suggest that its activity is mediated through stimulation of the pituitary-adrenal axis. The acute toxicity of the compound is very weak and gastric ulceration was not produced by the compound.

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Biophysical study of bioactive-substance conformation and interaction with drugs in solution

  • Yu, Byung-Sul;Lee, Bong-Jin;Sohn, Dong-Hwan
    • Archives of Pharmacal Research
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    • v.8 no.3
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    • pp.109-117
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    • 1985
  • The interaction of salicylic acid (S. A.), salicylamide (S,M) with nucleic acid base derivatives such as 9-ethyl adenine (A), 1-cyclohexyl uracil (U), 2', 3'-benzylidine-5' trityl-cytidine (C), gaunosine-2', 3', 5'-isobutylate (G) has been spectroscopically investigated to determine the binding mechanism. NMR and IR spectra were measured in nonpolar solvents. The association constant K of the formation of complex was calculated from the IR spectra. Compounds S. A. and A form a 1:1 or 1:2 cyclic hydrogen-bonded complex depending on the sample concentration. Compounds S. A. and U form a 1:1 or 1:2 hydrogen-bonded complex on the sample concentration. Compounds S. A. and C form a 2:1 hydrogen-bonded complex at low concentration (0.0016M). Compound S. A. binds compound G, but its binding does not completely break the self-association of compound G, Compound S. M. binds compounds A. U. C. G. very weakly.

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Synthesis of 2-(5,6-dimethoxy-l-indenyl)ethyl amine (2-(5,6-디메톡시-1-인데닐)에틸 아민의 합성)

  • 정원영;마은숙
    • YAKHAK HOEJI
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    • v.47 no.1
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    • pp.1-4
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    • 2003
  • In order to search the new serotonin bioisoster, 2-(5,6-dimethoxy-l-indenyl)ethyl amine(1) was synthesized. 3,4-Dimethoxybenzaldehyde, as starting material, was condensed with malonic acid in the presence of pyridine and piperidine to form 3,4-dimethoxycinnamic acid(2). Compound 2 was performed catalytic hydrogenation with 10% Pd-C to give propanoic acid derivative 3, which was cyclized by Friedel-Crafts acylation to afford 5,6-dimethoxyindan-l-one(4). Compound 4 was reduced with NaBH$_4$ in ethanol to obtain l-indanol 5, and it was dehydrated to give 5,6-dimethoxy-l-indene(6). This compound was lithiated with 2.5M n-butyllithium and reacted with 1,2-dibromoethane to give 2-(5,6-dimethoxy-l-indenyl)ethyl bromide(7), and which was treated with anhydrous ammonia to synthesize compound 1.