• Title/Summary/Keyword: Component Development

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Development and Research into Functional Foods from Hydrolyzed Whey Protein Powder with Sialic Acid as Its Index Component - III. Bacterial Reverse Mutation Testing of Hydrolyzed Whey Protein Powder Containing Normal Concentration of Sialic Acid (7%) with Enzyme Separation Method - (Sialic Acid를 지표성분으로 하는 유청가수분해단백분말의 기능성식품 개발연구 - III. 효소분리로 7% Siailc Acid가 표준적으로 함유된 유청가수분해단백분말의 미생물복귀돌연변이시험 연구 -)

  • Kim, Hee-Kyong;Noh, Hye-Ji;Cho, Hyang-Hyun;Koh, Hong Bum
    • Journal of Dairy Science and Biotechnology
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    • v.34 no.2
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    • pp.137-144
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    • 2016
  • The ultimate research goal of the current study was a development of hydrolyzed whey protein powder (7%-GNANA) manufactured with normal content of sialic acid, a marker compound, that is naturally occurring at 7% concentration in GMP obtained from the milk protein. GMP is a safe food, used worldwide in infant and baby foods, etc. The test substance was prepared using (7% sialic acid containing) GMP as a raw material, and then using alcalase, an enzyme approved as a food additive, after separation of sialic acid with 100% efficiency and 7%-GNANA (containing 7% sialic acid and protein; product name: HELICOBACTROL-7) provided by MEDINUTROL Inc. (Korea). Bacterial reverse mutation (Ames) test was conducted in accordance with GLP Guideline using the test substance specified above. To identify its mutagenic potential against microorganisms, histidine auxotrophic strains of Salmonella Typhimurium, TA98, TA100, TA1535, and TA1537, and tryptophan auxotrophic strain of Escherichia coli, WP2uvrA, were used. The bacterial reverse mutation (Ames) test was performed by dividing the test substances into five different concentration groups (0, 61.7, 185, 556, 1,670, $5,000{\mu}g/plate$). Results of this experiment did not reveal repetitive increase of colony generating values or positive criteria for reverse mutagenicity for any concentration of test substances in any of the five strains, regardless of the presence of a metabolic activation system, and no dose-dependency was identified. In conclusion, the safety of 7%-GNANA test substance was verified by bacterial reverse mutation test conducted before registration of 7%-GNANA as a food additive.

The Study on the Development and the Applicability of Consolidation Analysis Program Considering the Creep Strain (Creep 변형을 고려한 압밀해석 프로그램의 개발과 적용성 분석)

  • Kim, Su-Sam;Jeong, Seung-Yong;An, Sang-Ro
    • Geotechnical Engineering
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    • v.14 no.5
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    • pp.129-142
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    • 1998
  • This research is focused on the inducement of the constitutive equation considering the creep strain component and on the development of a finite element method program. The purpose of this research was to contribute to the design of construction structures or to the construction management in soft clay ground through predicting the long-term strain of construction structures reasonably bused on the above program. Modified Cam Clay model was adopted to describe the elastic-plastic behavior of clayey soil. And in the calculation of the creep sprain, the secondary coefficient of consolidation C. was applied for considering the volumetric creep element and the constants m, $\alpha$, A were rosed by the empirical creep equation proposed by Singh 8E Mitchell for considering the deviatoric creep element. To examine the reliability of the program which is developed in this study, the estimated values by this program were compared with the theoretical solution and the experimental results. And the applicability of the developed program was found to be reliable from the sensitive analysis of each parameters used in this study. According to the results obtained from the application of the program on the field measurement data, the estimated values by the program were found with be consistent with the actual values. And from the analysis of the displacement of embankments, the case of considering the creep behavior induced much fower errors than the case of neglecting it. But the results obtained from considering the volumetric creep behavior only were slightly underestimated the results from considering the deviator creep behavior showed the slightly overestimated values. Therefore, it remains the task of further studios to develop the laboratory test devices to obtain the reliable creep parameters, and to select the appropriate soil parameters, etc.

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A Study on Psychotherapy Supervisor's Education and Training Components (상담 수퍼바이저 교육과 훈련 요소 연구 : 수퍼바이저 발달 요인과 수퍼바이저 역량 요인 중심으로)

  • Chang, Semi;Chang, Sung-Sook
    • The Journal of the Korea Contents Association
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    • v.16 no.4
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    • pp.488-502
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    • 2016
  • Psychotherapy supervision has long been regarded as a crucial component of psychotherapy education. Supervisory role is very important in supervision outcomes but the absence of and need for supervisor's education and training have continued to be emphasized. Supervisor's education and training can be used to better prepare and strengthen new professionals who serve in the supervisory role. This study reviewed on the literatures of supervisor's education and training, psychotherapy supervisor's development, and core competencies in supervision. As a result of this study, it introduced what supervisor should be trained. There were supervisor identity, ability to build supervisory relationship/alliance, ability to provide effective and summative feedback, knowledge of professional supervision and value of commitment to lifelong learning and professional growth. Also consensus has converged on the superordinate value of now crucial components in educating and training supervisors: didactic instruction and experiential practice. In conclusion, I discussed what should be considered in Korean supervisor's education and training and future research directions.

Improved Drying Process for Electrodes in Production of Lithium-Ion Batteries for Electric Vehicles (전기자동차용 리튬이온 전지의 제조공정을 위해 개선된 극판 건조 기술)

  • Jang, Chan-Hee;Lee, Jae-Chon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.6
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    • pp.37-45
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    • 2018
  • An electric vehicle is an environmentally friendly vehicle because there is no exhaust gas, unlike gasoline automobiles. On the other hand, because the electric vehicle is driven by electric power charged in batteries, the distance to go through a single charge depends on the energy density of the batteries. Therefore, a lithium-ion battery with a high energy density is a good candidate for batteries in electric vehicles. Because the electrode is an essential component that governs the efficiency of a lithium-ion battery, the electrode manufacturing process plays a vital role in the entire production process of lithium-ion batteries. In particular, the drying process during the electrode manufacturing process is a critical process that has a significant influence on the performance. This paper proposes an innovative process for improving the efficiency and productivity of the drying process in electrode manufacturing and describe the equipment design method and development results. In particular, the design procedure and development method for enhancing the electrode adhesion power, atmospheric pressure superheated steam drying technology, and drying furnace slimming technologies are presented. As a result, high-speed drying technology was developed for battery electrodes through the world's first turbo dryer technology for mass production using open/integrated atmospheric pressure superheated steam. Compared to the conventional drying process, the drying furnace improved the productivity (Dry Lead Time $0.7min{\rightarrow}0.5min$).

Development of a Tool to Measure Suffering in Patients with Cancer (암환자의 고통 측정도구 개발에 관한 연구)

  • 강경아
    • Journal of Korean Academy of Nursing
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    • v.29 no.6
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    • pp.1365-1378
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    • 1999
  • This study is a methodological research study to develop an instrument to measure in patients with cancer and to test the validity and reliability of the instrument. The research procedure was as follows : 1) The first step was to develop conceptual framework based on a comprehensive review of the literature and in-depth interviews with patients with cancer. This conceptual framework was organized in to three dimensions (the intrapersonal dimension, the significant-other and context related dimension, the transcendental dimension). Initially 59 items were adopted. 2) These items were analyzed through the index of content validity(CVI) and 53 items were selected which met more than 80% on the CVI. 3) The pretest was carried out with 87 patients with cancer. After the pretest results were analyzed by item analysis, 44 items were selected. A second test of content validity was conducted and 6 items were eliminated considering the 80% CVI. 4) To test for reliability and validity, data collection was done during the period from January 25, 1999, to February 26, 1999. The subjects for the test were 160 patients with cancer and 185 healthy persons. analysis, item analysis and multitrait-multimethod method to analyze validity. The findings are as follows : 1) The Cronbach's alpha coefficient for internal consistency was .92 for the total 38 items and .79, .82, .85, for the three dimensions in that order. 2) The item analysis was based on the corrected item to total correlation coefficient( .30 or more) and information about the alpha estimate if this item was dropped from the scale. 3) As a result of the initial factor analysis using principal component analysis and varimax rotation, one item was deleted because of factor complexity (indiscriminate factor loadings). In the secondary factor analysis, 7 factors with eigenvalue of more than 1.0 were extracted and these factors explained 56 percents of the total variance. The seven factors were labeled as 'family relationship', 'emotional condition', 'physical discomfort', 'meaning and goal of life', 'contextual stimuli', 'change of body image', 'guilt feelings'. 4) The convergence effect between this instrument and the life satisfaction scale was identified and there was significant positive correlation(r= .52, p= .00). The discriminant validity between this instrument and the depression scale(CES-D) was tested and there was significant negative correlation(r= -.50, p= .00). The instrument for accessing the suffering of patients with cancer developed in this study was identified as a tool with a high degree of reliability and validity. In this sense, this tool can be effectively utilized for assessment in caring for patients with cancer.

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Development of a Framework for Anti-Collision System of Moving Drilling Machines on a Drill Floor (시추 작업장의 이동식 시추 장비 충돌 방지 시스템을 위한 프레임워크 개발)

  • Lee, Jaeyong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.4
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    • pp.330-336
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    • 2020
  • An anti-collision system between equipment is essential on a drill floor where multiple moving machines are operated simultaneously. This is to prevent accidents by halting the machines when required, by inspecting possibility of a collision based on the relative position data sent by the equipment. In this paper, we propose a framework for an Anti-Collision System (ACS) by considering expandability of the number of machines and computational speed, to promote development of drilling machines and corresponding ACS software. Each drilling equipment is represented as an object in the software with its own message format, and the message is constructed with serialization/deserialization to manage any additional equipment or data. The data handling process receives the current status of machines from the drilling control network, and relays a collision related message (including bypass signal) back to the machines. A commercial visualization software shows the bounding boxes moving with the equipment and indicates probable collision. It has been determined that the proposed system maintains total execution time below 5ms to process data from the network and relay the information hence, the system has no effect on the machine control systems having 100ms control cycle.

Effect of Light : Nutrients Ratio on the Zooplankton and Phytoplankton Community (동.식물플랑크톤 군집에 미치는 빛 : 영양염 비의 영향)

  • Jun, Man-Sig;Ryu, Kwang-Hyun;Kim, Moon-Sook;Park, Ju-Hyun;Park, Je-Chul
    • Korean Journal of Ecology and Environment
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    • v.42 no.3
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    • pp.295-302
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    • 2009
  • This study was conducted to identify the influences of light-to-nutrients ratio on the zooplankton and phytoplankton community. Various experiment conditions such as HL (high-light and without zooplankton), HLZ (high-light and with zooplankton), LL (low-light and without zooplankton), and LLZ (low-light and with zooplankton) were adjusted. Changes in biomass of phytoplankton species with the incubation time showed a similar tendency in the continuous cultures, but the change of species composition in the continuous cultures was detected. Cyanophyeeae (Phormidium sp.) seems to be affected by the existence of zooplankton. Also, the predominant species were Chlorophyceae (Staurastrum spp., S. dorsidentiferum, Coelastrum cambricam, Chlorella sp., Krichnerialla sp.) in a high-light environment and Bacillariophyceae (Melosyra granulata, Synedra acus, Fragilaria crotonensis) in a high-light environment. The estimated mean POC concentration (after twenty days) in a high-light environment was two times higher than that for a low-light environment. P : C ratio of seston component in a low-light environment was higher than that for a high-light environment. Changes in biomass of zooplankton species during the incubation time were higher than that for a high-light environment.

Concentration of Vanadium in Jeju Groundwater Using Reverse Osmosis Processes (역삼투 공정을 이용한 제주 지하수의 바나듐 농축)

  • Lee, Ho-Won;Moon, Soo-Hyoung;Ko, Kyung-Soo
    • Membrane Journal
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    • v.18 no.3
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    • pp.241-249
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    • 2008
  • This study is to concentrate vanadium in Jeju groundwater using reverse osmosis processes, and to utilize the concentrate for vanadium water. Groundwater samples were taken from Wahyul, Ayum, and Seogwipo groundwater wells with different in vanadium content each other. Their vanadiuln concentrations were 31.8, 44.5, and 53.0 ppb, respectively. The rejection coefficients of every component in groundwater were increased with the increase of TMP At the TMP of $8 kg_f/cm^2$, the rejection coefficients of vanadium, sodium, potassium, aluminium, iron, and barium were $97.4%{\sim}99.0%,\;97.7%{\sim}97.8%,\;98.0%{\sim}98.3%,\;94.8%{\sim}97.5%,\;88.0%{\sim}96.4.0%$, and $97.9{\sim}98.0%$, respectively. And those of magnesium, calcium, chromium, mauganese, and strontium in three groundwater were more than 99.0% at the same TMP. It was possible that vanadium contents of Wahyul, Ayum and Seogwipo groundwater were concentrated into 58.6, 118.9, and 165.1 ppb, respectively, by 6 stages treatment at the recovery ratio of 15%. And these concentrated water (vanadium water) did not exceed the permissible drinking water standards.

Development of a Stress ECG Analysis Algorithm Using Wavelet Transform (웨이브렛 변환을 이용한 스트레스 심전도 분석 알고리즘의 개발)

  • 이경중;박광리
    • Journal of Biomedical Engineering Research
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    • v.19 no.3
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    • pp.269-278
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    • 1998
  • This paper describes a development of efficient stress ECG signal analysis algorithm. The algorithm consists of wavelet adaptive filter(WAF), QRS detector and ST segment detector. The WAF consists of a wavelet transform and an adaptive filter. The wavelet transform decomposed the ECG signal into seven levels using wavelet function for each high frequency bank and low frequency bank. The adaptive filter used the signal of the seventh lowest frequency band among the wavelet transformed signals as primary input. For detection of QRS complex, we made summed signals that are composed of high frequency bands including frequency component of QRS complex and applied the adaptive threshold method changing the amplitude of threshold according to RR interval. For evaluation of the performance of the WAF, we used two baseline wandering elimination filters including a standard filter and a general adaptive filter. WAF showed a better performance than compared filters in the noise elimination characteristics and signal distortion. For evaluation of WAF showed a better performance than compared filters in the noise elimination characteristics and signal distortion. For evaluation of results of QRS complex detection, we compared our algorithm with existing algorithms using MIT/BIH database. Our algorithm using summed signals showed the accuracy of 99.67% and the higher performance of QRS detection than existing algorithms. Also, we used European ST-T database and patient data to evaluate measurement of the ST segment and could measure the ST segment adaptively according to change of heart rate.

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Select the Properties of Storytelling Effects on the Festival of Brand Equity and Reactive (스토리텔링 선택속성이 축제의 브랜드 자산과 사후 행동의도에 미치는 영향)

  • Kim, Hyun-Cheo;Jeon, In-Oh
    • The Journal of the Korea Contents Association
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    • v.13 no.10
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    • pp.480-494
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    • 2013
  • Globally branded culture festival in the region as a key component to the originality and distinction and with local residents and visitors to share experience and has succeeded in branding through Mind. Than mimics festivals in competitive and differentiated cultures containing festivals create a unique festival brand, and through the cultural and economic competitiveness, as well as the phase of the World Festival and preserve local culture and identity. Developing The best areas will be an asset. In order to build this world-class festival brand differentiation strategy above all, must be a top priority, Discrimination discovery and development of the local culture and sensibility in the age of the most powerful marketing tool that is being presented through storytelling brand assets to be passed on to visitors should. Thus the creation of storytelling festivals. Sensitivity of the festival right direction and in an era of paradigm key drivers of the local economy, such as image enhancement, and building long-term regional development and differentiation based on quality of life by creating a local culture can improve will Region's cultural and economic areas, the most important resource for the success of the festival is uniformly short-term planning and configuration, tube-driven operating as a one-sided non-participation. Sharing. Communication with an emphasis on the application of storytelling that is essential is considered.