• Title/Summary/Keyword: Compliance Model

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Rice-based breakfast improves fasting glucose and HOMA-IR in Korean adolescents who skip breakfast, but breakfast skipping increases aromatic amino acids associated with diabetes prediction in Korean adolescents who skip breakfast: a randomized, parallel-group, controlled trial

  • Kim, Hyun Suk;Jung, Su-Jin;Jang, Soyoung;Kim, Min Jung;Cha, Youn-Soo
    • Nutrition Research and Practice
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    • v.16 no.4
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    • pp.450-463
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    • 2022
  • BACKGROUND/OBJECTIVES: Adolescents who skip breakfast have an increased prevalence of chronic diseases. Thus, we aimed to evaluate whether the intake of rice-based breakfast had positive effects on blood glucose indices and to determine the possibility of diabetes prevalence in Korean youths who habitually skip breakfast. SUBJECTS/METHODS: In this randomized parallel-group controlled trial, 81 subjects who were suitable for compliance among 105 middle-and high-school students aged 12-18 years who usually skipped breakfast were included in this study (rice-meal group [RMG], n = 26; wheat-meal group [WMG], n = 29; general-meal group [GMG], n = 26). The RMG and WMG received a rice-based breakfast and a wheat-based breakfast for 12 weeks, respectively. The anthropometric indices, blood glucose indices, and metabolites were measured at baseline and the endpoint, respectively. RESULTS: The mean body weights in the RMG, WMG, and GMG groups at the endpoint were 62.44 kg, 61.80 kg, and 60.28 kg, respectively, and the mean body weights of the WMG and GMG groups at the endpoint were significantly higher than that at baseline (P < 0.05). The levels of fasting insulin and homeostasis model assessment of insulin resistance (HOMA-IR) values were significantly decreased in the RMG group at the endpoint compared to baseline (P < 0.05, P < 0.05, respectively). The levels of tryptophan and tyrosine in the WMG group at the endpoint were significantly higher than that those at baseline (P < 0.01, P < 0.05, respectively). CONCLUSIONS: Rice-based breakfast has positive effects on fasting insulin levels and HOMA-IR in Korean adolescents who skip breakfast. Additionally, it was found that a skipping breakfast could increase the prevalence of diabetes in adolescents who skip breakfast. Therefore, in addition to reducing breakfast skipping, it is vital to develop a rice-based menu that fits teenage preferences to prevent chronic diseases such as diabetes.

Nonlinear Optimization Analysis of the Carryover Policy in the 2nd Compliance Period of the Korean Emissions Trading Scheme (배출권거래제 2차 계획기간 중 이월한도 정책에 대한 비선형최적화 분석)

  • Jongmin Yu;Seojin Lee
    • Environmental and Resource Economics Review
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    • v.32 no.3
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    • pp.149-166
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    • 2023
  • The emissions trading system, introduced to reduce greenhouse gas emissions, experienced a sharp increase in emission allowance prices during the second plan period (2018-2020), which led to an increase in the demand for smooth supply and demand of emission allowances, while suppliers anticipating a shortage of emission allowances in the future did not participate in trading. Therefore, the authority temporarily revised the guidelines to ensure that the amount of allowances carried forward is proportional to the trading volume as a market stabilization measure. Through an optimization process using a dynamic nonlinear mathematical model, this paper analyzes the impact of the government's intervention on the carryover policy on GHG emission reductions and emission allowance market prices. According to the simulation analysis results, banking regulations could cause a decline in prices during the regulation period, even though the initial policy was predicted to be adopted.

The effect and therapeutic compliance of adjuvant therapy in patients with cholangiocarcinoma after R0 resection: a retrospective study

  • Han Taek Jeong;Joonkee Lee;Hyeong Ho Jo;Ho Gak Kim;Jimin Han
    • Journal of Yeungnam Medical Science
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    • v.40 no.1
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    • pp.65-77
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    • 2023
  • Background: This study aimed to compare clinical outcomes between surveillance and adjuvant therapy (AT) groups after R0 resection for cholangiocarcinoma (CCA). Methods: A total of 154 patients who underwent R0 resection for CCA at the Daegu Catholic University Medical Center between January 2010 and December 2019 were included. Overall survival (OS) and progression-free survival (PFS) were analyzed. Results: The median follow-up duration was 899 days. There were 109 patients in the AT group and 45 patients in the surveillance group. The patients in the AT group were younger (67 years vs. 74 years, p<0.001) and included more males (64.2% vs. 46.7%, p=0.044). The proportion of patients with stage III CCA was larger in the AT group than in the surveillance group (13.8% vs. 2.2%, p=0.005). In addition, AT did not improve OS (5-year OS rate, 69.3% in the AT group vs. 64.2% in the surveillance group, p=0.806) or PFS (5-year PFS rate, 42.6% in the AT group vs. 48.9% in the surveillance group, p=0.113). In multivariate analysis using the Cox proportional hazards model, stage III CCA (hazard ratio [HR], 10.81; 95% confidence interval [CI], 2.92-40.00; p<0.001) was a significant predictor of OS. American Society of Anesthesiologists classification II (HR, 0.50; 95% CI, 0.31-0.81; p=0.005), and American Joint Committee on Cancer stages II (HR, 3.14; 95% CI, 1.25-7.89; p=0.015) and III (HR, 8.08; 95% CI, 2.80-23.32; p<0.001) were independent predictors of PFS. Conclusion: AT after R0 resection for CCA did not improve OS or PFS.

Influencing Factors of Christians' COVID-19 Health Prevention Behavior (기독교인의 코로나19 건강예방행위 영향 요인)

  • Seol-Young Bang;Nam-Ju Je;Mee-Ra Park
    • Journal of the Korean Society of Industry Convergence
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    • v.26 no.2_2
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    • pp.293-306
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    • 2023
  • The purpose of this study is a descriptive research study to analyze the factors that affect Christians' COVID-19 preventive behavior. The subjects of the study were 262 adult Christians, and the data collected were using SPSS 25.0 and AMOS 21.0 programs. As a result of the study, the subject's religious maturity level was 4.21 ± .55 points out of 5 points, COVID-19 stress was 2.86 ± .73 points out of 5 points, optimism bias was 2.94 ± 1.26 points out of 7 points, and COVID-19 preventive health behavior was 4 points. The total score was 3. 54 ± . 44 points. As a result of the correlation analysis of the subject's religious maturity, COVID-19 stress, optimistic bias, and COVID-19 preventive health behaviors, COVID-19 preventive health behaviors were faith maturity (r=.156, p=.012), COVID-19 stress (r=.216, There was a positive correlation with optimism bias (r=174, p=.005). In conclusion, it can be said that the higher the religious maturity, the higher the COVID-19 stress, and the higher the optimistic bias, the better the preventive health behavior of COVID-19, and the explanatory power of the overall model was 9.4%. In the post-COVID-19 era, it is necessary to develop educational programs that can prevent infectious diseases and promote health in the community.

KRG and its major ginsenosides do not show distinct steroidogenic activities examined by the OECD test guideline 440 and 456 assays

  • Namkyu Lee;Ju Hyeong Lee;Ji Eun Won;Youn Ji Lee;Sun Hee Hyun;Yeong-Deuk Yi ;Gyo In;Hee Dong Han;YoungJoo Lee
    • Journal of Ginseng Research
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    • v.47 no.3
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    • pp.385-389
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    • 2023
  • Background: Ginseng has been used as a traditional medicine for treatment of many diseases and for general health maintenance. Previously, we showed that ginseng did not demonstrate estrogenic property in ovariectomized mouse model. However, it is still possible that disruption of steroidogenesis leading to indirect hormonal activity. Methods: The hormonal activities were examined in compliance with OECD guidelines for detecting endocrine disrupting chemicals: test guideline (TG) No. 456 (an in vitro assay method for detecting steroidogenesis property) and TG No. 440 (an in vivo short-term screening method for chemicals with uterotrophic property). Results: Korean Red Ginseng (KRG) and ginsenosides Rb1, Rg1, and Rg3 did not interfere with estrogen and testosterone hormone synthesis as examined in H295 cells according to TG 456. KRG treatment to ovariectomized mice did not show a significant change in uterine weight. In addition, serum estrogen and testosterone levels were not change by KRG intake. Conclusion: These results clearly demonstrate that there is no steroidogenic activity associated with KRG and no disruption of the hypothalamic-pituitary-gonadal axis by KRG. Additional tests will be performed in pursuit of cellular molecular targets of ginseng to manifest mode of action.

Development of an Occupational Safety and Health (OSH) Guide for Safely Cleaning Contaminated Machinery, Equipment, and Parts Used in the Electronics Manufacturing Process (전자산업 공정에서 사용한 부품, 기계류 세정(cleaning) 작업 안전보건 가이드)

  • Seunghee Lee;Soyeon Kim;Kyung Ehi Zoh;Yeong Woo Hwang;Kyong-Hui Lee;Kwang Jae Chung;Dong-Uk Park
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.33 no.4
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    • pp.419-426
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    • 2023
  • Objectives: This study aims to develop an Occupational Safety and Health (OSH) guide for the safe cleaning of contaminated machinery, equipment, and parts used in the electronics manufacturing process. Methods: A literature review, field investigations, and discussions were conducted. An initial draft of an OSH guide was developed and reviewed by experts with significant experience in maintenance work in the electronics manufacturing process in order to refine the guide. Results: Workers involved in cleaning processes with chemicals, solvents, and abrasive blasting can face exposure to a wide range of chemicals, abrasives, and noise. Identifying potential risks associated with each cleaning technique was an essential first step toward enhancing safety measures. The OSH guide comprises approximately eleven to twelve sections spanning 20-25 pages. It includes engineering and administrative protocols systematically organized to address the necessary actions before, during, and after cleaning tasks, depending on the technique. It is recommended that airline respirator masks be used in conjunction with an air purification system to ensure adherence to air quality standard "D" for atmosphere level. The use of an oil-free air compressor is advised, preferably a stationary model that does not rely on fuel sources like diesel. Conclusions: This OSH guide is designed to protect workers involved in maintenance activity in the electronics industry and aligns with global standards, such as those from the International Organization for Standardization (ISO) and Semiconductor Equipment and Material International, ensuring a higher level of safety and compliance.

The Influence of Information Security Related Work Stress on Information Security Policy Resistance through Job Burnout (정보보안 관련 업무 스트레스가 직무 소진을 통해 정보보안 정책 저항에 미치는 영향)

  • In-Ho Hwang
    • The Journal of the Korea institute of electronic communication sciences
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    • v.19 no.2
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    • pp.427-436
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    • 2024
  • Recently, the importance of information security (IS) has been socially recognized, leading organizations to adopt IS policies, secure specialized personnel, and demand IS compliance from employees. However, the implementation of these policies can disrupt existing work processes, causing resistance among employees. This study aims to elucidate the mechanism linking work stress, caused by IS policies that do not consider the work system, to individual job burnout and IS policy resistance. We established a research model and hypotheses based on previous studies and utilized structural equation modeling with data collected from organization members of companies that have implemented IS policies. The results of the structural equation modeling confirmed that work ambiguity and work impediment are linked to IS policy resistance through job burnout, characterized by emotional exhaustion and disengagement. Our findings suggest that the swift implementation of IS policies can provoke a backlash from employees, with stress being the primary cause. This paradoxically indicates the need for the development of organization-specific IS policies.

Neoadjuvant chemoradiotherapy versus immediate surgery for resectable and borderline resectable pancreatic cancer: Meta-analysis and trial sequential analysis of randomized controlled trials

  • Shahab Hajibandeh;Shahin Hajibandeh;Christina Intrator;Karim Hassan;Mantej Sehmbhi;Jigar Shah;Eshan Mazumdar;Ambareen Kausar;Thomas Satyadas
    • Annals of Hepato-Biliary-Pancreatic Surgery
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    • v.27 no.1
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    • pp.28-39
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    • 2023
  • We aimed to compare resection and survival outcomes of neoadjuvant chemoradiotherapy (CRT) and immediate surgery in patients with resectable pancreatic cancer (RPC) or borderline resectable pancreatic cancer (BRPC). In compliance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement standards, a systematic review of randomized controlled trials (RCTs) was conducted. Random effects modeling was applied to calculate pooled outcome data. Likelihood of type 1 or 2 errors in the meta-analysis model was assessed by trial sequential analysis. A total of 400 patients from four RCTs were included. When RPC and BRPC were analyzed together, neoadjuvant CRT resulted in a higher R0 resection rate (risk ratio [RR]: 1.55, p = 0.004), longer overall survival (mean difference [MD]: 3.75 years, p = 0.009) but lower overall resection rate (RR: 0.83, p = 0.008) compared with immediate surgery. When RPC and BRPC were analyzed separately, neoadjuvant CRT improved R0 resection rate (RR: 3.72, p = 0.004) and overall survival (MD: 6.64, p = 0.004) of patients with BRPC. However, it did not improve R0 resection rate (RR: 1.18, p = 0.13) or overall survival (MD: 0.94, p = 0.57) of patients with RPC. Neoadjuvant CRT might be beneficial for patients with BRPC, but not for patients with RPC. Nevertheless, the best available evidence does not include contemporary chemotherapy regimens. Patients with RPC and those with BRPC should not be combined in the same cohort in future studies.

A Study on the Seismic Response of a Non-earthquake Resistant RC Frame Using Inelastic Dynamic Analyses (비선형 동적 해석을 이용한 비내진 상세 RC 골조의 지진거동 특성 분석)

  • Jeong, Seong-Hoon;Lee, Kwang-Ho;Lee, Soo-Kueon
    • Journal of the Korea Concrete Institute
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    • v.22 no.3
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    • pp.381-388
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    • 2010
  • In this study, characteristics of the seismic response of the non-earthquake resistant reinforced concrete (RC) frame were identified. The test building is designed to withstand only gravity loads and not in compliance with modern seismic codes. Smooth bars were utilized for the reinforcement. Members are provided with minimal amount of stirrups to withstand low levels of shear forces and the core concrete is virtually not confined. Columns are slender and more flexible than beams, and beam-column connections were built without stirrups. Through the modeling of an example RC frame, the feasibility of the fiber elementbased 3D nonlinear analysis method was investigated. Since the torsion is governed by the fundamental mode shape of the structure under dynamic loading, pushover analysis cannot predict torsional response accurately. Hence, dynamic response history analysis is a more appropriate analysis method to estimate the response of an asymmetric building. The latter method was shown to be accurate in representing global responses by the comparison of the analytical and experimental results. Analytical models without rigid links provided a good estimation of reduced stiffness and strength of the test structure due to bond-slip, by forming plastic hinges closer to the column ends. However, the absence of a proper model to represent the bond-slip poased the limitations on the current inelastic analysis schemes for the seismic analysis of buildings especially for those with round steel reinforcements. Thus, development of the appropriate bond-slip model is in need to achieve more accurate analysis.

Seismic Performance Evaluation of Post-Northridge WUF-B Connections Frame (Post-Northridge WUF-B 접합부 골조의 내진 성능 평가)

  • Han, Sang Whan;Moon, Ki Hoon;Jung, Ji Eun;Lee, Ki Hak
    • Journal of Korean Society of Steel Construction
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    • v.19 no.6
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    • pp.751-760
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    • 2007
  • The purpose of this study is to evaluate the seismic performance of the frame which is assumed to be used with Welded Unreinforced Flange-Bolted web (WUF-B) connections and detailed in compliance with FEMA 350 recommended seismic design criteria. In FEMA 350, these types of connections are only valid for Ordinary Moment-Resisting Steel Frames (OMRSFs). For this purpose, based on test results, we proposed an analytical model for the Post-Northridge WUF-B connections with different panel zone strength ratios. Using the connection model, SAC Phase II three and nine-story frames were modeled and analyzed. From a nonlinear static pushover analysis, ductility, maximum strength, and the maximum interstory drift ratio were investigated for buildings with Post-Northridge details. Moreover, the maximum interstory drift ratio of each performance level (IO and CP) was also investigated through Incremental Dynamic Analysis (IDA). Analytical results were compared with those of buildings with either Pre-Northridge connection or ductile connections with no fracture. The analytical results showed that buildings with Post-Northridge WUF-B connections provide superior strength and interstory drift ratio capacity than buildings with Pre-Northridge WUF-B connections.