• Title/Summary/Keyword: Complex treatment

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Anti-Acne Effects of Herbal Complex in Acne Vulgaris Mouse Model (마우스 모델에서의 생약복합제의 여드름 치료 효능)

  • Lee, Ki Man;Lee, Geum Seon;Shim, Hong;Oh, Se Koon;Park, Il Ho;Yim, Dongsool;Kang, Tae Jin
    • Korean Journal of Pharmacognosy
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    • v.43 no.4
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    • pp.323-327
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    • 2012
  • Acne, also known as Acne vulgaris, is a common disorder of human skin involving the sebaceous gland and Propionibacterium acnes (P. acnes). The purpose of this study was to demonstrate whether anti-acne herbal complex (AAHC), a functional extract from herbal complex can be used for acne treatment as a natural product. We first demonstrated anti-acne activity of AAHC in mouse acne model. Acne was induced by injecting P. acnes on the backside $2{\times}10^7$ CFUs in ICR mice and then the mice were treated with AAHC by dermal application once daily. ACFREE$^{(R)}$ (clindamicin phosphate) was used as a positive control. Treatment with AAHC decreased the P. acnes-induced skin swelling and inflammation. AAHC treatment significantly decreased serum DHT concentration in acne-induced mice. Especially, treatment of 20% AACH in mice was more effected than 40%. We next evaluated the antimicrobial property of AAHC against P. acnes, Staphylcococcus aureus (S.aureus), and Escherichia coli (E. coli). Incubation of P. acnes, S. aureus, and E. coli with AAHC showed minimal inhibitory concentration (MIC) values against the bacterial growth lower. Alamar blue method was also carried for the antibacterial activity. It was effectively MIC level at 6.25% of P. acnes. AAHC effectively inhibited the growth of S. aureus and E. coli at 0.097% on MIC level, respectively. Our results showed the potential of using AAHC as an alternative treatment for antibiotic therapy of acne and the application of AAHC as a herbal medicine for acne treatment.

SOx and NOx removal performance by a wet-pulse discharge complex system (습식-펄스방전 복합시스템의 황산화물 및 질소산화물 제거성능 특성)

  • Park, Hyunjin;Lee, Whanyoung;Park, Munlye;Noh, Hakjae;You, Junggu;Han, Bangwoo;Hong, Keejung
    • Particle and aerosol research
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    • v.15 no.1
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    • pp.1-13
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    • 2019
  • Current desulfurization and denitrification technologies have reached a considerable level in terms of reduction efficiency. However, when compared with the simultaneous reduction technology, the individual reduction technologies have issues such as economic disadvantages due to the difficulty to scale-up apparatus, secondary pollution from wastewater/waste during the treatment process, requirement of large facilities for post-treatment, and increased installation costs. Therefore, it is necessary to enable practical application of simultaneous SOx and NOx treatment technologies to remove two or more contaminants in one process. The present study analyzes a technology capable of maintaining simultaneous treatment of SOx and NOx even at low temperatures due to the electrochemically generated strong oxidation of the wet-pulse complex system. This system also reduces unreacted residual gas and secondary products through the wet scrubbing process. It addresses common problems of the existing fuel gas treatment methods such as SDR, SCR, and activated carbon adsorption (i.e., low treatment efficiency, expensive maintenance cost, large installation area, and energy loss). Experiments were performed with varying variables such as pulse voltage, reaction temperature, chemicals and additives ratios, liquid/gas ratio, structure of the aeration cleaning nozzle, and gas inlet concentration. The performance of individual and complex processes using the wet-pulse discharge reaction were analyzed and compared.

Effects of Complex Korean Medicine Treatment on a Patient with Knee Pain and Ankylosis Following a Distal Femur Osteotomy: A Case Report

  • Park, Han Bin;Heo, Eun Sil;Yoo, Dong Hwi;Jang, Won Suk;Kwon, Oh Bin;Choi, Ki Won;Kwon, Min Jin;Kim, Tae Ju;Jang, Seon Woo;Kwon, Oh Hoon
    • Journal of Acupuncture Research
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    • v.39 no.2
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    • pp.134-138
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    • 2022
  • Distal femur osteotomy (DFO) is a controlled surgical break of the femur performed to allow realignment of the limb. Redistribution of the load aims to correct the abnormal mechanical weight-bearing axes in patients with abnormal alignment of the lower extremities, and degenerative changes in the knee joint. This report describes a complex Korean medicine treatment for a patient complaining of knee pain and stiffness following a DFO. Post-operative care for the patient lasted 78 days with treatment including pharmacopuncture, acupuncture, herbal medicine, cupping therapy, and physiotherapy. The effectiveness of the treatments was evaluated using the numerical rating scale, range of motion of the knee, and by physical examination. After treatment, these evaluation indicators improved, suggesting that the complex Korean medicine treatment received by the patient was an appropriate treatment for knee pain and stiffness following a DFO.

A Study on the Synthesis of [RCOOH]-$\varepsilon$-Caprolactam-Montmorillonite Intercalations-complex and its Isothermal Decomposition in High Vacuum ([RCOOH]-$\varepsilon$-Caprolactam-Montmorillonite 층간화합물의 합성과 고진공상태하에서의 등온 분해에 관한 연구)

  • 조성준
    • Journal of the Korean Ceramic Society
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    • v.33 no.8
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    • pp.909-914
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    • 1996
  • In this research [RCOOH]-$\varepsilon$-Caprolactam-Montmorillonite was synthesized by reaction between Na-Mont-morillonite (10-Carboxy-n-decyl)dimethylethylammonium (=RCCOH) ion and $\varepsilon$-Caprolactame-Motmorillonite ob-tained was 3.62$\AA$ After heat treatment of this intercalations complex at 37$^{\circ}C$ in high vacuum for 12 h 24 h, 40 h and 90 h the basal spacing was reduced to 35.8$\AA$, 34.2, 17.5 $\AA$ and 16.6$\AA$ respectively. The calculated amount of free $\varepsilon$-caprolactame included int he intercaltions complex and that of $\varepsilon$-caprolactame which is interca-lated into the interlayer space of montomorillonite and still remained after heat treatment are 4.6~4.9 and 0.5 molecules per unite cell of montmorillonite respectively.

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TREATMENT OF FACIAL MULTIPLE COMPLEX FRACTURES;CASE REPORTS (안면부 다발성 복잡골절의 치료;증례보고)

  • Kim, Young-Kyun;Yeo, Hwan-Ho;Yang, In-Seog
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.16 no.2
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    • pp.208-214
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    • 1994
  • Successful treatment of patients with multiple complex facial bone fractures is dependent on the precise clinical and diagnostic image, well-established systematic principles of fracture repair. The oral and maxillofacial surgeon should appreciate the postoperative complications and minimize or manage adequately. Most of complications can be treated secondarily, but we should appreciate the fatal complications which are impossible to treat.

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The clinical observation of 1 case of the Complex Regional Pain Syndrome (소염약침으로 치료한 복합부위통증증후군(CRPS) type I 환자 1례 증례보고)

  • Lee, Eun-Jung;Yoon, Il-Ji
    • Journal of Haehwa Medicine
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    • v.18 no.1
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    • pp.109-116
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    • 2009
  • Objective: The objective of this study is to observe the effect of anti-inflammatory herbal acupuncture on the Complex Regional Pain Syndrome Methods : Anti-inflammatory herbal acupuncture, A-Shi Point, Sa-am acupunture were used to treat shoulder pain & ROM(range of movement)disorder, chest pain, finger's causalgic pain. We evaluated the patient through VAS(Visual Analog Scale) daily and Physical Examinations Results & Conclusions : After 42days of treatment, shoulder pain was decreased from VAS10 to VAS3, chest pain was decreased from VAS10 to VAS1.5, finger's causalgic pain was decreased from VAS10 to VAS2.5. and the patient showed that the ROM(range of movement) of shoulder was better, oriental treatment is good method for pain relief and better movement.

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Clinical Case of Liver Cirrhosis, with Herbal Medicine, Acupuncture, and Moxibustion Treatment (간경변 환자의 한방치험례)

  • Shin, Woo-Jin
    • The Journal of Internal Korean Medicine
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    • v.30 no.1
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    • pp.241-248
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    • 2009
  • Object : Liver cirrhosis is a disease of the liver in which normal cells are replaced by scar tissue. The purpose of this case is to report the improvement of liver cirrhosis after herb-med, acupuncture & moxibustion complex therapy. Methods : We provided herb-med, acupuncture & moxibustion complex therapy to a patient who suffered from ascites and fatigue. We examined LFT & Child-Pugh class to evaluate the effectiveness of oriental treatment. Result and Conclusion : We observed that herb-mod. acupuncture & moxibustion complex therapy decreased symptoms of liver cirrhosis and improved general condition of a patient who suffered from ascites and fatigue. In the LFT result, Child-Pugh class was improved.

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Complex Korean Medicine Therapy for Tinnitus with Ear Fullness, Depression, and Anxiety: A Case Report (이충만감 및 불안, 우울 소견을 동반한 이명 환자의 복합 한의진료 경과 : 증례보고)

  • Moon, Hyang-ran;Jo, Hee-Geun
    • The Journal of Internal Korean Medicine
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    • v.41 no.6
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    • pp.1300-1306
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    • 2020
  • Background: The aim of this study was to determine the clinical effects of complex Korean medicine therapy for tinnitus associated with ear fullness, depression, and anxiety. Case Report: A 52-year-old female patient suffering from tinnitus with ear fullness, depression, and anxiety was treated with acupuncture, pharmacopuncture, and herbal medicine. We used the Tinnitus Handicap Inventory (THI), Beck Depression Inventory (BDI-II), Beck Anxiety Inventory (BAI), and a Verbal Numerical Rating Score (VNRS) to assess the patient's symptoms. The administration of the acupuncture, pharmacopuncture, and herbal medicine improved the ear fullness, depression and anxiety symptoms. No side effects were observed during the treatment. Conclusion: The study findings suggest that complex Korean medicine therapy, such as acupuncture, pharmacopuncture, and herbal medicine, may be effective for the treatment of tinnitus associated with ear fullness, depression, and anxiety.

Study on the Development of a Probiotics Complex for Weaned Pigs

  • Xuan, Z.N.;Kim, J.D.;Heo, K.N.;Jung, H.J.;Lee, J.H.;Han, Y.K.;Kim, Y.Y.;Han, In K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.10
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    • pp.1425-1428
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    • 2001
  • This study was conducted to investigate the effects of supplementation of a probiotics complex on growth performance, nutrient digestibility, diarrhea score and microbial population in pigs weaned at 21 days of age. Treatments were 1) control A (0.2% antibiotics, Avilamycin), 2) control B (0.1 % $Ractocom^{(R)}$), 3) 0.1%, 4) 0.2% and 5) 0.3% probiotics complex; 80 pigs were used and each treatment had 4 replicates with 4 pigs per replicate (16 pigs per treatment). During phase I period (d 0 to 14), although there was no significant difference, pigs fed control B diet showed higher ADG (average daily gain) and better F/G (feed/gain) than any other treatments. During late experimental period (d 15 to 28), pigs fed diet supplemented with 0.2% probiotics complex showed slightly higher ADG. Overall (d 0 to 28) the diet that contained 0.2% probiotics complex gave slightly higher ADG and ADFI (average daily feed intake) than the other diets. In a metabolic trial using 20 piglets, nutrient digestibility showed the best results in pigs fed 0.2% probiotics complex diet, but not significantly different from other groups. Diarrhea score and microbial population status in intestine, colon and feces were not affected by dietary treatments. In conclusion, this study suggested that a newly developed probiotics complex can replace antibiotics in weaned pigs.

Marine derived Ca-Mg complex supplementation basal diet during four subsequent parities improved longevity and performance of sows and their litters

  • Santi Devi Upadhaya;Woo Jeong Seok;Shanmugam Suresh Kumar;Rudolf H. van der Veen;In Ho Kim
    • Journal of Animal Science and Technology
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    • v.65 no.3
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    • pp.562-578
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    • 2023
  • The aim of the present study was to evaluate the effects of dietary supplementation of Ca-Mg complex on the longevity and reproductive performance of sows. In total, seventy-two gilts ([Yorkshire × Landrace] × Duroc, average body weight 181 kg) were randomly allocated to 1 of 3 treatments during 4 successive parity in a 4 × 3 factorial arrangement. Treatments consisted of CON (basal diet), CM1 (basal diet -MgO - 0.3% limestone + 0.4% Ca-Mg complex), and CM2 (basal diet - MgO - 0.7% limestone + 0.4% Ca-Mg complex). A higher (p < 0.05) number of totals born and live piglets, and sows increased feed intake during gestation and lactation, increased backfat thickness, and increased estrus interval were observed (p < 0.05) during their third and fourth parity than during their first and second parity. Ca-Mg complex supplementation improved (p < 0.05) the number of total piglets during the first and second parity as well as live-born piglets during the first to third parity, reduction (p < 0.05) in backfat thickness during the third and fourth parity, a higher (p < 0.05) initial and final number of suckling piglets as well as higher weaning weight compared with sows fed CON diet during the first, second, and third parity. The average daily gain (ADG) was higher (p < 0.05) in piglets born to CM1 and CM2 sows regardless of parity. The treatment diets fed to sows lowered (p < 0.05) the duration of first to last piglet birth and placenta expulsion time compared with CON sows. A significant interactive effect (p = 0.042) between parities and treatment diets was observed for the first to last piglet birth. Thus, Ca-Mg complex supplementation by partially replacing limestone in the basal diet enhanced sow performance, specifically during their third and fourth parity, thereby improving sow longevity.