• Journal of Korean Society of Transportation
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• v.18 no.3
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• pp.77-86
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• 2000

The shortest path problem is one of the mathematical Programming models that can be conveniently solved through the use of networks. The common shortest Path Problem is to minimize a single objective function such as distance, time or cost between two specified nodes in a transportation network. The sing1e objective model is not sufficient to reflect any Practical Problem with multiple conflicting objectives in the real world applications. In this paper, we consider the shortest Path Problem under multiple objective environment. Wile the shortest path problem with single objective is solvable in Polynomial time, the shortest Path Problem with multiple objectives is NP-complete. A genetic a1gorithm approach is developed to deal with this Problem. The results of the experimental investigation of the effectiveness of the algorithm are also Presented.

• IMMUNE NETWORK
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• v.4 no.2
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• pp.88-93
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• 2004

Background: Bone marrow mesenchymal stem cells (MSC) inhibit the immune response of lymphocytes to specific antigens and dendritic cells (DC) are professional antigenpresenting cells whose function is to present antigen to naive T-lymphocytes with high efficiency and play a central role in the regulation of immune response. We studied the effects of MSC on DC to evaluate the relationship between MSC and DC in transplantation immunology. Methods: MSC were expanded from the bone marrow and DC were cultured from peripheral blood mononuclear cells (PBMNC) of 6 myelogenous leukemia after achieving complete response. Responder cells isolated from PBMNC and lysates of autologous leukemic cells are used as tumor antigen. The effect of MSC on the DC was analyzed by immunophenotype properties of DC and by proliferative capacity and the amount of cytokine production with activated PBMNC against the allogeneic lymphocytes. Also, cytotoxicity tests against leukemic cells studied to evaluate the immunologic effect of MSC on the DC. Results: MSC inhibit the CD83 and HLA-class II molecules of antigen-loaded DC. The proliferative capacity and the amount of INF-$\gamma$ production of lymphocytes to allogeneic lymphocytes were decreased in DC co-cultured with MSC. Also the cytotoxic activity of lymphocytes against leukemic cells was decreased in DC co-cultured with MSC. Conclusion: MSC inhibit the activation and immune response of DC induced by allogeneic or tumor antigen.

• IMMUNE NETWORK
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• v.12 no.3
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• pp.126-128
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• 2012

We report on a case of severe hepatotoxicity in a 52-year-old male with multiple myeloma (MM) who had received bortezomib therapy. At patient presentation, liver enzymes were normal, but started to markedly increase 3 days after the patient's second dose of bortezomib was administered, when free kappa light chains were noticeably reduced in the serum. After discontinuation of bortezomib, liver enzymes recovered gradually to baseline. Then, the patient was started on a thalidomide-containing regimen, which he was able to tolerate well. The patient achieved complete remission prior to autologous stem cell transplantation (ASCT). The patient underwent ASCT without occurrence of further liver toxicity.

• Archives of Craniofacial Surgery
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• v.18 no.1
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• pp.37-43
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• 2017

Background: Skin cancer is the most common type of cancer. Of the 4 million skin lesions excised annually worldwide, approximately 2 million are considered cancerous. In this study, we aimed to describe a regional experience with skin cancers treated by a single senior surgeon and to provide a treatment algorithm. Methods: The medical records of 176 patients with head and neck non-melanocytic skin cancer (NMSC) who were treated by a single surgeon at our institution between January 2010 and May 2016 were retrospectively reviewed, and their data (age, sex, pathological type, tumor location/size, treatment modality) were analyzed. Patients with cutaneous squamous cell carcinoma (cSCC) who were classified as a high-risk group for nodal metastasis underwent sentinel node mapping according to the National Comprehensive Cancer Network guidelines. Results: Among the patients with NMSC who were treated during this period, basal cell carcinoma (BCC; n=102, 57.9%) was the most common pathological type, followed by cSCC (n=66, 37.5%). Most lesions were treated by complete excision, with tumor-free surgical margins determined via frozen section pathology. Thirty-one patients with high-metastasis-risk cSCC underwent sentinel node mapping, and 17 (54.8%) exhibited radiologically positive sentinel nodes. Although these nodes were pathologically negative for metastasis, 2 patients (6.5%) later developed lymph node metastases. Conclusion: In our experience, BCC treatment should comprise wide excision with tumor-free surgical margins and proper reconstruction. In contrast, patients with cSCC should undergo lymphoscintigraphy, as nodal metastases are a possibility. Proper diagnosis and treatment could reduce the undesirably high morbidity and mortality rates.

• Journal of Families and Better Life
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• v.35 no.2
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• pp.17-29
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• 2017

The purposes of this study were to analyze the effect of perceived parent-adolescent communication on SNS addiction tendency among high school students and to investigate the mediating effects of self-control on the relationship between above variables. 567 students who were registered in three high schools located in D city completed a questionnaire on parent-adolescent communication, SNS addiction tendency, and self-control. Structural equation models were conducted to compare the research model (complete mediating effect) and the competing model (partial mediating effect), and bootstrapping was conducted to investigate the mediating effects of self-control with SPSS 23.0 and AMOS 23.0. The results are as follow: First, while the parent-adolescent communication did not directly have an effect the SNS addiction tendency, the self-control had a direct effect on the SNS addiction tendency. Second, the research model was selected as a final model which implied that parent-adolescent communication had an indirect effect on SNS addiction tendency among high school students. Third, self-control had a significant mediating effect on the relationship between parent-adolescent communication and high school students' SNS addiction tendency. Based on the results of this study, it can be concluded that parent-adolescent communication had an indirect effect rather than a direct effect through self-control on high school students' SNS addiction tendency. This result indicates that the SNS addiction tendency rate of high school student can be lowered, by mediating self-control. Finally, this study suggests that the implicit points on counseling methods to remedy self-control of high school students, and shortcomings and limits of this study and advice for follow-up studies all be discussed.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.41 no.12
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• pp.67-74
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• 2004

AES is frequently used as a symmetric cryptography algorithm for the Internet. Wireless embedded systems increasingly use more conventional wired network protocols. Hence, it is important to have low-cost implementations of AES for thor The basic architecture of AES unrolls oかy one full cipher round which uses 20 S-boxes together with the key scheduler and the algorithm repeatedly executes it. To reduce the implementation cost further, the folded architecture which uses only eight S-box units was studied in the recent years. In this paper, we will study a low-cost AES implementation for wireless communication technology based on the folded architecture. We first improve the folded architecture to avoid the sixteen bytes of additional state memory. Then, we implemented a single byte architecture where only one S-box unit is used for data encryption and key scheduling. It takes 352 clocks to finish a complete encryption. We found that the maximum clock frequency of its FPGA implementation reaches about 40 MHz. It can achieve about 13 Mbps which is enough for 3G wireless communication technology.

• Journal of the Korean Society for Precision Engineering
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• v.30 no.9
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• pp.901-908
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• 2013

The introduction of industrial intelligent robot using vision sensor has been interested in automated factory. 2D and 3D vision sensors have used to recognize object and to estimate object pose, which is for packaging parts onto a complete whole. But it is not trivial task due to illumination and various types of objects. Object image has distorted due to illumination that has caused low reliability in recognition. In this paper, recognition method of complex shape object has been proposed. An accurate object region has detected from combined binary image, which has achieved using DoG filter and local adaptive binarization. The object has recognized using neural network, which is trained with sub-divided object class according to object type and rotation angle. Predefined shape model of object and maximal slope have used to estimate the pose of object. The performance has evaluated on ETRI database and recognition rate of 96% has obtained.

• The Journal of the Convergence on Culture Technology
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• v.3 no.2
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• pp.43-48
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• 2017

5G will bring revolutionary development in mobile communication, and it is anticipated to have complete commercialization including mass adoption rate by 2020s. High number of smart devices including IoT, wearable devices, etc., which have high amount of data usage, will involve even higher data traffics. In addition, media dependency and demand is rapidly rising. These environmental aspects will necessity and sufficient condition for successful implementation of 5G mobile communication system. In this paper, global cooperation and competition for 5G technology leadership will be analyzed and summarized. Through this, proper solution to maintain competency of Korea in future will be proposed.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.11 no.6
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• pp.193-205
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• 2011

This paper suggests $p$-facility locations in $m$ candidate locations and $n$ areas in optimal cost side(population${\times}$shortest distance). This problem has been classified by NP-complete because there is not a polynomial time algorithm. In this paper, we suggests reverse-delete method that deletes a candidate facility one by one from $p=m$ until $p=2$. As a result of the proposed algorithm for the $5{\times}5$ and $7{\times}7$, the initial solution is obtained. For the Swain's 55-node network, we obtain the optimal solution through a solution improvement process with $p=4$ and it by using the initial solution with $p=5$.

• Current Industrial and Technological Trends in Aerospace
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• v.6 no.1
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• pp.44-55
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• 2008

Catalyzed by the recent development of space technology, various kinds of spacecrafts were launched and utilized with purposes in many developed countries. In case of emergency such as natural disasters, proper satellite images are required in order to help to mitigate and assess the effects of disasters on human life and property. Since there are limitations for a nation to single-handedly operate a satellite and fulfill complete demands, a development need of international cooperation organization to share satellite images among the member countries has risen. In this paper, preestablished four international organizations' background, objectives, and operating system, and their principal characteristics were analyzed and compared. Especially, the paper has focused on the analysis of on-going operating procedures and its cases for International Charter, UN SPIDER's development of local supporting network to support NFP, establishment of Web-GIS by Sentinel Asia under the goal of 'Digital Asia', and the utilization of GEO that is widely applied in natural disaster fields.