• 대한한의학회지
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• 제31권2호
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• pp.71-77
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• 2010

Objectives: We investigated whether oriental medical therapy influences the results of in vitro fertilization-embryo transfer. Methods: 19 women with infertility were treated by oriental treatment from August 1999 to June 2000 in the department of obstetrics and gynecology of an oriental medical center. The women were planning in vitro fertilization-embryo transfer after oriental medicine treatment. The data from the women was analyzed, we obtained the following results. Results: The average age of infertile women was $35.42{\pm}4.86$; infertility caused by male factor or tubal factor were the most frequent. The average number of previous failed IVF treatments was $2.21{\pm}1.81$. The number of aspirated oocytes was $9.00{\pm}6.09$ in IVF cycle before oriental therapy, increasing to $9.80{\pm}5.41$ after therapy, but it was not statistically significant. In IVF before oriental therapy, the average number of embryos transfer was $3.20{\pm}1.90$, and it significantly increased to $4.40{\pm}1.45$ after treatment. The quality points of embryos were $10.00{\pm}6.02$ before treatment, but statistically significantly improved to $14.07{\pm}4.98$ after. The characteristics of women being pregnant and non-successful women were compared with age, period of taking herbal medicine and the number of failed IVF treatments, but there was no significant difference. Conclusion: Oriental treatment before IVF could be expected to have good results in treatment of infertility.

• 성인간호학회지
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• 제19권1호
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• pp.144-154
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• 2007

Purpose: This descriptive study was conducted to identify the use of complementary and alternative therapies, and the perception and attitudes toward CAT in Korean adults. Methods: The 1,010 study subjects were recruited from ten regions in South Korea. Data were collected from July to September, 2004. Results: The 43.2% of the sample(n=436) had an experience of using CAT. The subjects using CAT was more likely to have high score in the CAT perception compared to the subjects with no experience of CAT(p=.001). The primary source of information about CAT was mass media(59.7%). The 52.4% of the sample answered that CAT was supplementary and the 27.7% answered CAT was applicable to chronic pain or musculoskeletal disorders. Subjects(34.8%) pointed out that the greatest problem was no scientific informant in the use of CAT. The primary reason of using CAT was to maintain their health or to prevent disease(44.0%), and the 59.0% of the subjects responded that CAT was effective. Majority of subjects were satisfied with CAT(63.3%) and experienced no side effects of CAT(90.6%). Conclusion: This study suggests that professional counseling and education for CAT is needed for Korean public as well as the research approach to test the effects of CAT.

• 대한한의학회지
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• 제27권3호
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• pp.151-168
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• 2006

Objectives: To help the Oriental medicine clinical studies for the common cold treatment, this study analyzed the tendency of research into complementary medicine on the common cold recently published in PubMed. Methods: This study analyzed 26 research papers on complementary medicine on the common cold published in PubMed Over the past 10 years. It measured annually and for each country the number of papers published, the number of subjects, the period of research, the area of trial, the method of study, the objective of study, and intervention, respectively and intervention, the objective of study, and the result of trials overall. Results: There were research papers concerning treatment, prevention, safety of herbal medicine, inducement, and improvement of symptoms of the common cold in the study objective the most among them concerned treatment of the common cold. There were more positive results compared to negative results for treatment and prevention. The results for safety and symptom improvement were positive, while the results for the inducement were indeterminate. There were research papers about using food and medicine, acupuncture, hydrotherapy, and cold exposure in intervention the most among them were about using food and medicine. The food and medicine interventions were Echinacea preparations, vitamins, zinc preparations, Baptisia, Thuja, the root of North American ginseng, probiotic bacteria, troxerutin, garlic, Andrographis paniculata, and caffeine. The use of Echinacea preparations was the most frequent among them. Conclusions: Recent research results of complementary medicine on the common cold were more positive than negative.

• 대한예방한의학회지
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• 제17권3호
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• pp.1-18
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• 2013

Objectives: Korea has a dual medical system where traditional Korean Medicine (KM) and Western Medicine (WM) exist au equal terms with exclusive practice boundaries. The aim of this study was to identify complementary and substitute relationships between KM and WM in Korea. Methods: The data of 19,413 respondents were collected from the 2009 Korea Health Panel dataset. General characteristics and the medical utilization of respondents were analyzed descriptively. the Univariable Analysis was used to compare the factors that affected KM and WM utilization, and the Multivariable Analysis was applied to identify complementary or substitute relationships between the respondents' choices for KM and WM. The data were analyzed by the seven disease groups; diseases of nervous system, circulatory system, respiratory system, digestive system, skin and subcutaneous tissue, musculoskeletal system, and connective tissue, injury, poisoning and others. Results: 13.6% and 76.9% of respondents used KM and WM respectively last 12 mouths. 12.7% used both, and 0.9% used KM only. In overall, respondents who visited KM institutions used also WM. However, according to the analysis of choices of medical institutions, non-pharmacological KM treatment and WM has been used as a substitute for another in the diseases of the skin and subcutaneous tissue, diseases of the musculoskeletal system, and connective tissue, injury, poisoning and others. Conclusions: Despite some exceptional disease areas, Korean people use KM complementarily to WM, and this result can rationalize the recent Korean government policies encouraging the cooperation of KM and WM. This study can he used for the future policies development for KM service delivery.

• 대한한의학회지
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• 제34권4호
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• pp.32-45
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• 2013

Objectives: This study aimed to evaluate oriental medical research on dysmenorrhea published within 10 years to analyze the trends of study on dysmenorrhea at home and abroad for progress in future clinical research. Methods & Results: Publication research was carried out on several online database systems using keywords like 'dysmenorrhea', 'traditional medicine', 'herb', 'acupuncture', 'CAM', 'complementary and alternative medicine', 'moxibustion' within 10 years(2002-2012). 32 Korean journal articles and 29 oversea journal articles were selected. Conclusions: This study concludes that more well-designed randomized-controlled studies and diverse approaches are necessary to make accumulation of evidence on oriental medical therapy of dysmenorrhea.

• 대한한방내과학회지
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• 제19권1호
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• pp.505-523
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• 1998

Aroma therpay in the western classical medicine is compared with the mechanistic paradigm of Newton physics which is the foundation of western modern medicine. It is the therapy whose basic principle is very similar to the basic concepts of oriental medicine lasting thousands of years. We know that parts of their therapies are explained by Yin-Yan and five elements in Oriental Medicine. In the modern western medicine, as preventive medicine is becoming more and more important and moreover, health promotion and self healing care is being emphasized, Maintenanayce which is the oriental preventive medicine, acts in concert with the concept of New Age of Science and provides a way for the Oriental Medicine of the future. The health promotion and self healing care is similar to the thought of Maintenanayce in Oriental Medicine. Oriental Medicine has provided the concept of preventive ehaling care for a long time and built the foundation of the department of Maintenanayce. Among these method of Preservation of Health, We could find that of using fragrance throuth the several references. By comparing the department of Maintenanayce in oriental preventive medicine with the books and papers about aroma therapy, used in the fields of naturalpathy medicine, alternative medicine, and complementary medicine in the west, and by analyzing them, centering around references, to see whether they are reasonable and corresponding, the following conclusions have been reached. 1. We could see that aroma therapy of oriental preventive medicine could be applied to the fields of health promotion and self healing cure, recently appearing in the world of health medicine, as a modern way of Preservation of Health(養生). 2. We could see that western traditional aroma therapy take important position in alternative medicine and complementary medicine, and it could be developed as the transitional field of medical cure for the interchange between western and eastern medicine. 3. We could see that aroma therapy is not totally unknown therapy and there is some points of similarity in the traditional references of oriental medicine. Also, it is considered that the aroma therapy has a possibility of coming the front as an general therapy among various therapies. 4. aroma therapy will be actively applied to many fields such as oriental psychiatry, internal medicine of the respiratory system, pediatrics, oriental nursing, oriental dermatologic beauty, and preventive medicine. Therefore, we have a view that the combination between aroma therapy and oriental medicine will be fairly valuable to study as the general and transtional middle step on which it will prepare the situation of oriental medicine's reimportation from the west and we establish a bridgehead to export the oriental medicine.

• 대한한방내과학회지
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• 제33권3호
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• pp.317-326
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• 2012

Objectives : To investigate the prevalence and utilization pattern of complementary and alternative medicine (CAM) in individuals with type 2 diabetes. Methods : We conducted a nationwide survey and a total of 535 individuals with type 2 diabetes were asked about their demographic, diabetes-related characteristics and CAM use. We used multiple logistic regression modeling to determine independent predictors of CAM use. Results : Of the 535 subjects, 417 (77.9%) used CAM in last 12 months. The most commonly used modality was red ginseng (17.9%). CAM use was independently associated with being married, northern area residence, higher education and diabetes duration of 3-5 years. More than half(58.3%) of the CAM users used it expecting a better outcome in addition to conventional therapy. Information sources about CAM were mostly friends (36.0%) and family (31.9%), only 28.1% of diabetic patients seek counsel from medical doctors or oriental medical doctors about CAM. Many people perceived CAM as effective (62.7%) and reported side effects only rarely (1.2%). Conclusions : Many diabetic patients used CAM and found it effective, which urges clinicians to pay attention to CAM use of their diabetic patients. Also, further studies are required regarding efficacy and safety about CAM.

• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7755-7758
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• 2015

Background: There is increasing evidence that HER2-neu is an important biomarker in gastric carcinomas (GC) and gastroesophageal junction (GEJ) adenocarcinomas. The aim of this study was to evaluate HER2-neu expression and also some clinicopathological features of these neoplasms. Materials and Methods: We selected 211 paraffin-embedded blocks, 193 GC and 18 GEJ. Then 4 micron sections were prepared for staining with hematoxylin and eosin and also for IHC (Her2-neu). The Chi-square test was used for significance between expression of HER2-neu and clinicopathological parameters. Results: In patients with advanced cancer of GC and GEJ, HER2-neu overexpression was more associated with the intestinal cancer subtype. Conclusions: This could be a guide to new complementary therapy for affected patients.

• The Korean Journal of Physiology and Pharmacology
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• 제27권1호
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• pp.1-8
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• 2023

Hypothyroidism alone can lead to myocardial fibrosis and result in heart failure, but traditional hormone replacement therapy does not improve the fibrotic situation. Hydrogen sulfide (H₂S), a new gas signaling molecule, possesses anti-inflammatory, antioxidant, and anti-fibrotic capabilities. Whether H₂S could improve hypothyroidism-induced myocardial fibrosis are not yet studied. In our study, H₂S could decrease collagen deposition in the myocardial tissue of rats caused by hypothyroidism. Furthermore, in hypothyroidism-induced rats, we found that H₂S could enhance cystathionine-gamma-lyase (CSE), not cystathionine β-synthase (CBS), protein expressions. Finally, we noticed that H₂S could elevate autophagy levels and inhibit the transforming growth factor-β1 (TGF-β1) signal transduction pathway. In conclusion, our experiments not only suggest that H₂S could alleviate hypothyroidism-induced myocardial fibrosis by activating autophagy and suppressing TGF-β1/SMAD family member 2 (Smad 2) signal transduction pathway, but also show that it can be used as a complementary treatment to conventional hormone therapy.

• 대한예방한의학회지
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• 제21권3호
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• pp.29-42
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• 2017

Background : Efforts towards increasing insurance coverage for traditional Korean medicine (TKM) are being continued. However, various difficulties are faced in generating evidence for TKM due to limited financial support and the low quality of research methodology. Objectives : The objectives of this study were to review the Swiss evaluation program for complementary and alternative medicine (CAM) and assess the expansion in public health insurance coverage of complementary medicine as approved by referendum in Switzerland. Methods : The regulations of CAM in the European Union were assessed. Research articles, reports, government publications and websites which deal with the 'Programm Evaluation $Komplement{\ddot{a}}rmedizin$ (PEK)' and the referendum in Switzerland were searched for and analyzed. Results : The PEK was conducted from 1998 to 2005. The PEK evaluated the efficacy, utilization and cost-effectiveness of anthroposophical medicine, homeopathy, neural therapy, phytotherapy and traditional Chinese medicine. However, clear conclusions could not be drawn from the evaluation according to the PEK Report. Later, a referendum was implemented in which 5 therapies would be added to the Switzerland Constitution with the support of the public. The coverage of CAM was approved by Swiss a plebiscite with an approval rate of 67.0%. Conclusions : The reason for the successful referendum is suggested to be public support and the solidarity with CAM experts and politicians. It may be surmised that recognition of the political efforts and scientific aspects required to expand insurance coverage of TKM, and towards obtaining public support, is necessary.