• 대한한방내과학회지
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• 제42권3호
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• pp.279-292
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• 2021

Objectives: Analyze papers on the effect of acupuncture on cancer pain from a macroscopic point of view, suggesting global trends and future research directions to promote acupuncture treatment for cancer pain. Methods: By filtering the papers searched for (acupuncture) AND (cancer pain) in the Web of Science database, 351 papers were selected and analyzed by year, field, journal, institution, author, and keyword. Results: Most papers were published in 2020, and research was active in the field of complementary and alternative medicine. Research on the effects of acupuncture in cancer pain has been active in cancer centers and university hospitals, research has been active in various countries. The most frequently mentioned keywords in the titles and abstracts were acupuncture, pain, and quality of life. The latest top 5 keywords were inhibitor-induced arthralgia, acupuncture therapy, risk factors, opioids, and recovery. Conclusions: Acupuncture treatment has the potential to reduce pain and improve quality of life in cancer patients, and it should be actively studied in the future.

• 지역과문화
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• 제7권4호
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• pp.49-68
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• 2020

현대인의 정신질환에 대한 보완의학 연구는 학문적 분야별로 이루어져 왔다. 심리치료, 미술치료, 문학치료, 무용치료 등이 그 중 하나지만 이러한 비통합적 연구를 현실에 적용하기는 극히 제한적이다. 약물치료 후 보완책을 모색하는 의료계와의 협업도 문제고, 이를 정책적으로 제도화하기는 더욱 어렵다. 이에 본 연구는 대부분의 치료 프로그램이 중시하는 공간의 가치를 연구해 공간 중심의 치료 패러다임으로의 전환을 제언하였다. 독일에서 발달해 국내에 유입된 통합문학치료학의 이론을 기저로 고찰하고 테트라시스템을 우리의 문화유산이도 한 고택 공간에 대입해 적용했다. 그리고 고택 공간의 특성을 치료 프로그램화 하는 방안을 샘플로 제시해 보았다. 안동시의 권성백 고택을 대표적인 공간으로 보고 분석해 보았다. 유사 사례로서 힐리언스 선마을, 독일의 크나이프 마을, 봉은사 템플스테이를 살펴보고 공간의 활용 실태를 파악하였다. 이에 고택 공간들을 테트라시스템으로 분석해 걷기, 시 쓰기, 풍욕, 편지 쓰기 등의 공간치료 프로그램을 제시하였다. 이는 공간의 장소화와 장소성을 프로그램에 접목하는 시초의 연구로서 의미가 크다 할 것이다.

• Parasites, Hosts and Diseases
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• 제51권4호
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• pp.413-419
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• 2013

The mainstay therapy against leishmaniasis is still pentavalent antimonial drugs; however, the rate of antimony resistance is increasing in endemic regions such as Iran. Understanding the molecular basis of resistance to antimonials could be helpful to improve treatment strategies. This study aimed to recognize genes involved in antimony resistance of Leishmania tropica field isolates. Sensitive and resistant L. tropica parasites were isolated from anthroponotic cutaneous leishmaniasis patients and drug susceptibility of parasites to meglumine antimoniate (Glucantime$^{(R)}$) was confirmed using in vitro assay. Then, complementary DNA-amplified fragment length polymorphism (cDNA-AFLP) and real-time reverse transcriptase-PCR (RT-PCR) approaches were utilized on mRNAs from resistant and sensitive L. tropica isolates. We identified 2 known genes, ubiquitin implicated in protein degradation and amino acid permease (AAP3) involved in arginine uptake. Also, we identified 1 gene encoding hypothetical protein. Real-time RT-PCR revealed a significant upregulation of ubiquitin (2.54-fold), and AAP3 (2.86-fold) (P<0.05) in resistant isolates compared to sensitive ones. Our results suggest that overexpression of ubiquitin and AAP3 could potentially implicated in natural antimony resistance.

• 대한한방부인과학회지
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• 제21권4호
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• pp.228-236
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• 2008

Purpose: The purposes of this study is to provide basic informations on oriental medical research and treatment through analysis of breast cancer patients, who visited M $\mu$ integrative cancer center, O O university East-West neo medical center. Methods: Electronic medical records of 106 breast cancer patients who visited oriental medical center from June 2, 2006 to February 28, 2008 were selected to collect clinical data of those patients. Clinical data were analyzed for types of clinical characteristics, and received therapies. For analysis of survival and recurrence, Kaplan-Meier method was used. All the data were processed and analyzed using SPSS version 13.0. Results: Average age of breast cancer patients, who visited oriental medical center was 48.72 ($\pm$10.13). The stage distribution record indicated stage I (5.8%), stage II (7.0%), stage III (5.8%), and stage IV (81.4%). Original purposes of patients were analyzed to be supplementary treatment for western therapy (68.9%), treatment for recurrence prevention (18.9%), and oriental medical treatment (12.2%) in order. While receiving oriental medical treatment, 60.4% of patients received conventional medical treatment simultaneously. Conclusion: Majority of patients who visited oriental medical hospital were stage IV at terminal stage and mainly visited for the purpose of supportive care. Further clinical study of breast cancer patients is needed to validate the effectiveness of oriental medical treatment based on this study.

• 대한간호학회지
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• 제43권5호
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• pp.669-680
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• 2013

Purpose: This study was done to explore the process of accepting CATs among nurses who experienced CATs in Korea. Methods: Grounded theory methodology was utilized. Data were collected from 10 nurses during individual in-depth interviews. Theoretical sampling was used until the data reached saturation. Data were analyzed using the constant comparative analysis method. Results: The core category emerged as "resolving the doubt and integrating" explaining the process of accepting CATs. The nurses engaged in three stages: need awareness, look for solution and integration. Causal conditions were interest as a nursing intervention and orthodox medical limitations. Context was lack of basis for application and increase in social interest. Strategies were new knowledge acquisition, having a strong will, combined with existing knowledge, and individualized intervention. Intervening conditions were others' eye, exhaustion for nurses and physical environment. Consequences were expanding of the nursing role and improved nurse satisfaction. Conclusion: The results of the study should facilitate application of CATs in nursing practice. To help nurses who are interested in CATs, there is a need for education programs, and further research on CATs.

• 한국임상수의학회지
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• 제23권3호
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• pp.314-319
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• 2006

To determine the antimicrobial and anti-inflammatory efficacy of Opuntia ficus-indica for chronic otitis, we evaluated the effects of topical applications of the methanol extracts with 20 cases of dogs which had chronic malignant otitis by pathogens with antibiotic resistance. The dogs had revealed recurrent symptoms of malignant otitis and were not treated by conventional therapeutic agents. However, in this study, the clinical cure rates of Opuntia ficus-indica was 75% and the average alleviation period was $1.21{\pm}0.42$ week, and the mean recovery period was $1.06{\pm}1.06$ week after the initiation of treatment. As the results of this study, topical Opuntia ficus-indica extracts was found to be highly effective for the treatment of chronic malignant otitis with clinical cure rates of 75% within 1.06 weeks of therapy. Further evaluation of Opuntia ficus-indica extracts will allow us to establish and to optimize the therapeutic strategy for the malignant otitis in veterinary practice, and the potential usefulness of this complementary treatment on recurrent infectious pathology.

• 한국방사선학회논문지
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• 제13권7호
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• pp.925-932
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• 2019

플라스틱 섬광체와 상용 50 mm, f1.8 렌즈 및 고감도 CMOS 카메라를 사용하여 방사선치료 시 흡수선량을 측정할 수 있는 광 도시메트리 시스템을 구축하였다. 아울러 촬영된 방사선 분포 영상에 대한 비네팅 보정, 기하학적 왜곡 보정, 스케일 보정을 통하여 화소값으로 선량을 교정하는 절차를 확립하였다. 개발된 광 도시메트리 시스템을 6 MV 의료용 선형가속기에 대하여 선량 특성 평가를 수행한 결과, 심부선량백분율은 이온챔버로 측정한 결과에 비하여 빌드 업 깊이 이상에서는 오차 범위 2% 이내로 일치하였으며, 90% 조사야에 대하여 2.8%의 평탄도가 측정됨에 따라 방사선치료선량 측정 시스템으로서의 충분한 활용가능성을 확인하였다.

• 대한한방부인과학회지
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• 제30권4호
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• pp.149-174
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• 2017

Objectives: The aim of this study is to establish a base for further research by reviewing studies on electroacupuncture (EA) for stress urinary incontinence (SUI). Methods: Clinical studies concerning the effects of EA for SUI, were obtained from Cochrane Library, PubMed, CNKI, RISS, NDSL, KISS and OASIS. Results: Forty-five studies met the criteria, which included 33 RCTs, 1 pilot RCT, 4 non-randomized Clinical Trials, 6 Case studies and 1 Orthogonal design study with 3638 patients. There was only one article published in Korea. In these study, the most common primary outcome measurement was the pad test. Most of the studies showed the group treated by EA effects compared to the control group. Also, many interventions that combined with EA were found and all complex therapy group had significantly better than control group. 7 studies observed adverse events (AEs), four of which referred to EA related AEs among them. And 4 studies reported no AEs associated with EA. Conclusions: Despite several limitations, various studies to prove limited yet effective EA on SUI provides much significance. Subsequent studies conducted by the complementary systematic review of the studies and well-designed clinical trials using the methodological quality will be needed to more firmly validate the therapeutic effect of EA on SUI.

• 사상체질의학회지
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• 제28권4호
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• pp.403-411
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• 2016

Objectives Dyspnea due to neuromuscular disease is very rare in the complementary medicine field. The purpose of this study is to report a case which showed sypmtoms improvement after treatment with Sohaphyang-won. Methods To evaluate the results of this treatment, number of days which the patient had dyspnea, results of an Arterial blood gas analysis, and the patient's lab reports were measured. Results The patient who suffered from severe sudden dyspnea and applying mechanical ventilator, was treated by Sohaphyang-won and acupuncture therapy for about 2 months. He had been diagnosed as dyspnea caused by neuromuscular disease, which in Western medicine there was no specific treatment. But after treated with Sohaphyang-won and acupuncture, his frequency of dyspnea decreased. Conclusions This study suggests that using Sasang constitutuional medical treatment is effective for Soeumin patient with dyspnea induced by neuromuscular disease.

• Journal of Digestive Cancer Research
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• 제3권1호
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• pp.17-20
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• 2015

췌장암은 예후가 좋지 않은 악성 질환으로 진단 당시 10-20%에서만 수술적 절제가 가능한 것으로 알려져 있다. 수술적 절제가 유일한 근치적 치료로 알려져 있으나, 높은 재발률로 인해 예후가 좋지 않아 예후를 개선시키기 위한 항암화학요법이나 방사선요법 등의 보조적 치료가 시도되고 있다. 수술 후 보조항암요법이 시행되고 있으나 생존율의 향상은 미비한 수준으로 최근에는 항암화학요법, 항암방사선요법, 항암화학요법 후 항암방사선요법 등의 다양한 선행보조항암요법이 시행되고 있다. 본 종설에서는 절제 가능한 췌장암과 국소진행성 췌장암에서의 선행보조항암요법에 대한 최근의 연구를 정리하고 임상적인 역할에 대해 규명해 보고자 한다.