• Asian-Australasian Journal of Animal Sciences
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• 제30권5호
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• pp.672-682
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• 2017

Objective: This study was conducted to investigate the effects of probiotic, prebiotic and synbiotic with and without feed restriction on broilers performance, blood parameters, carcass characteristics, and feed cost of production from 1 to 56 days of age. Methods: Two hundred and forty unsexed one day-old chicks of Arbor Acres breed were used. Two trials, I and II, were conducted, with 120 birds in both. Each trial was divided into 4 equal groups. The birds in trial I were fed ad libitum throughout the experiment, while the chicks in trial II were fed ad libitum during the first week of age, then subjected to 5 hours/d of feed restriction from the beginning of the second week up to the end of the experiment. In both trials, the birds in group 1 were fed on a control diet while the other groups were given the same control diet supplemented either with a probiotic in group 2, prebiotic in group 3, or synbiotic in group 4. Results: It was found that chicks fed diets supplemented with probiotic, prebiotic and synbiotic (with and without feed restriction) exhibited higher body weight and feed efficiency than chicks fed the control diets. The feed additives in both trials did not affect hemoglobin, serum total protein, albumin, globulin, glucose, and total cholesterol, except the packed cell volume which was increased in the additive treatments with restriction at the end of the experiment. Moreover, the dietary treatments did not influence the carcass yield. However, the relative weights of liver, gizzard and proventriculus, small intestine and bursa of fabricius were found to be increased. The additives decreased the visible fat in the carcass, with more decreasing effect in the additive groups with restriction. The lowest feed cost per kg of weight gain was observed in the birds fed diets supplemented with synbiotic, probiotic and prebiotic. Feed restriction improved the feed conversion ratio, economic return, but decreased the feed intake, serum total cholesterol and visible fat in comparison with non-restricted groups. Conclusion: The biological feed additives could be routinely added to broiler diets, especially when a feed restriction program is followed. Finally, it can be recommended to restrict feed, and add probiotic or synbiotic to increase weight, improve feed conversion rate and reduce feed cost of production.

• 한국식품영양과학회지
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• 제39권12호
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• pp.1800-1806
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• 2010

본 연구는 1일 1.5 L씩 4주간의 바나듐수 음용이 비진행성 암환자의 피로감 개선에 긍정적인 효과를 미치는 지 확인하기 위하여 수행되었다. 본 연구 결과 4주간의 바나듐수 음용은 비진행성 암환자의 피로감 개선을 위해 통계적으로 경계선상의 유의성을 보였으므로 향후에는 탐색형 연구로부터 확증형 연구를 통하여 피험자 수가 증가할 경우 통계학적으로 유의성을 보일 것이라고 예상되므로 근거 확보를 위한 진일보한 연구가 이루어져야 할 것이다. 즉 1일 1.5 L씩 4주간의 바나듐수 음용은 비진행성 암환자의 피로감 개선에 대해 유의수준 10%에서 통계적으로 유의한 차이가 나타났다. 이는 바나듐수가 암 환자의 피로에 도움이 되고 또한 참여자 수가 늘어날 경우 통계학적으로 유의성을 보일 것이라는 최소한의 근거를 보여주는 것이다. 향후에는 피험자수의 증가를 비롯하여 성별, 암종별 피험자수를 매치하고 피로감 개선을 포함한 기타 추가 기능에 대한 연구 수행을 기대할 수 있겠다.

• Journal of Dental Anesthesia and Pain Medicine
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• 제22권4호
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• pp.295-304
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• 2022

Background: The first dental experience is vital in molding a child's attitude towards dentistry and dental outcomes. The cooperation of a child during dental treatment is essential to render successful and high-quality treatment. Dental anxiety is common in children undergoing dental treatment. The success of pediatric dental treatments and patient comfort depends on controlling the levels of patient anxiety in clinical settings. This study aimed to compare the effectiveness of the recorded maternal voice and virtual cognitive tool (Roogies application) in the management of pediatric dental patients. Methods: The study was carried out with children aged of 4-7 years [n = 80, (40 male and 40 female)], without any past dental history, and were randomly allocated into two groups. After informed consent was obtained, the entire procedure was explained to the parents. Anxiety was assessed pre-, during, and post-treatment by measuring pulse rate, and recording Venham Picture Test (VPT) scores. Group A [n = 40; 20 boys and 20 girls)] was provided with a headphone that played a recorded maternal voice. Group B [n = 40; 20 boys and 20 girls)] was administered the virtual cognitive tool. After conditioning the children, oral prophylaxis was performed for both groups. A comparative evaluation was conducted for each treatment session. Results: The intra-group comparison of VPT scores and heart rate for patients assigned to the recorded maternal voice showed a statistically significant difference in dental anxiety (P-value ≤0.001). Conclusion: This study demonstrated that a reduction in dental anxiety with the help of recorded maternal voice forms an important component of non-pharmacological behavior management. Alternatively, the use of a virtual cognitive tool as an anxiety-reducing technique can also be advocated.

• Journal of Acupuncture Research
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• 제28권2호
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• pp.43-47
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• 2011

Objectives : The purpose of this study is to investigate the effectiveness of treating low back pain patients with Wan-Gwa acupuncture. Methods : Clinical study was conducted to 42 patients who were treated in Dept. of Acupuncture and Moxibusion, Woosuk University Hospital from March 1 to December 31, 2010. Subject were randomly divided into two groups. In one group(control group), patients were treated with acupuncture. And in the other group(test group), patients were treated with both acupuncture and Wan-Gwa acupuncture. To estimate the efficacy of treatments, visual analog scale(VAS) and Oswestry disability index(ODI) were checked. 13 patients were excluded and we investigated 14 patients of control group and 15 patients of test group entirely. Results : 1. In both two groups, VAS and ODI of patients were decreased significantly in the statistics 2. In test group, ODI of patients were decreased more significantly in the statistics than ODI of patients in control group. Conclusions : We suggest that cotreatment of acupuncture and Wan-Gwa acupuncture on low back pain patients can be recommended as a useful therapy.

• Journal of Korean Neurosurgical Society
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• 제46권3호
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• pp.226-231
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• 2009

Objective : We describe our clinical experiences and outcomes in patients who had thromboembolic complications occurring during endovascular treatment of intracerebral aneurysms with a review of the literature. The types of thromboembolic complications were divided and the treatment modalities for each type were described. Methods : Between August 2004 and March 2009 we performed endovascular embolization with Guglielmi detachable coils for 173 patients with 189 cerebral aneurysms, including ruptured and unruptured aneurysms at our hospital. Sixty-eight patients were males and 105 patients were females. The age of patients ranged from 22-82 years (average, 58.8 years). We retrospectively evaluated this group with regard to complication rates and outcomes. The types of thromboembolic complications were classified into the following three categories: mechanical obstruction, distal embolic stroke, and stent-induced complications, which corresponded to types I, II, and III, respectively. A comparison of the clinical results was made for each type of complication. Results : Only eight patients had a thromboembolic complication during or after a procedure (4.6%). Of the eight patients, two had a mechanical obstruction as the causative factor; the other three patients had distal embolic stroke as the causative factor. The remaining three patients had stent-induced complications. In cases of mechanical obstruction, recanalization occurred due to the use of intra-arterial thrombolytic agents in one of two patients. Nevertheless, a poor prognosis was seen. In the cases of stent-induced complications, in one of three patients in whom a thrombus developed following stent insertion, a middle cerebral artery territory infarct developed with a poor prognosis despite the use of wiring and an intra-arterial thrombolytic agent. In the cases of distal embolic stroke, all three patients achieved good results following the use of antiplatelet agents. Conclusion : Treatment for thromboemboic complications due to mechanical obstruction and stent-induced complications include antiplatelet and intra-arterial thrombolytic agents; however, this cannot guarantee a sufficient extent of effectiveness. Therefore, active treatments, such as balloon angioplasty, stent insertion, and clot extraction, are helpful.

• Asian-Australasian Journal of Animal Sciences
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• 제32권8호
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• pp.1122-1127
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• 2019

Objective: The objective of current study was to investigate the lactation performance and rumen fermentation characteristics of dairy cows fed a diet with alfalfa hay replaced by corn stover but supplemented with molasses. Methods: Sixteen Holstein cows in mid-lactation were randomly assigned to 1 of 2 dietary treatments: i) alfalfa based diet (AH), and ii) corn stover based diet supplemented with molasses (CSM). The experiment was conducted according to a $2{\times}2$ crossover design with 22-d each period, consisting of 17 d for adaptation and 5 d for data and samples collection. Results: Dry matter intake and milk yield were higher for cows fed AH than CSM (p<0.01). Milk protein content and nitrogen conversion were higher (p<0.05), while milk urea nitrogen was lower (p<0.01) for cows fed AH than CSM-fed cows. Contents of milk total solids, fat and lactose were not different between two groups (p>0.10). Total rumen volatile fatty acid concentration tended to be higher (p = 0.06) for cows fed AH than CSM-fed cows. Molar proportion of acetate was lower (p = 0.04), but valerate was higher (p = 0.02) in cows fed AH than CSM-fed cows. Rumen concentration of propionate, and isobutyrate, and ratio of acetate to propionate tended to be different (p<0.10) between two groups. The feed cost per kilogram of milk was lower in CSM than AH (p<0.01). No differences were found in feed efficiency and most plasma parameters tested (p>0.10). Conclusion: In comparison with AH diet, CSM diet could be fed to dairy cows without negative effect on feed efficiency, ruminal fermentation, but economically beneficial, indicating that CSM could be an alternative choice for dairy farms instead of AH to feed midlactation dairy cows.

• 대한물리치료과학회지
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• 제15권3호
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• pp.19-29
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• 2008

Background : Ankle inversion sprains are one of the most common injuries in sports and activities of daily living that mostly concern physically active individuals. In most researches, proprioceptive deficit, muscle weakness and/or absent coordination have been regarded as a contributing factors. Despite the high incidence of ankle sprain and instability, therapeutic approaches to properly manage the symptoms have rarely been investigated. This study aimed to identify the effect of proprioceptive exercise program that is easy to integrate in normal training program. Methods : Subjects were randomly allocated to control group and experimental group consisting of 11 and 10 patients, respectively. The conservative treatment for the control group consisted of hot packs, ultrasound and TENS. In addition, the experimental group performed 7 exercises to enhance proprioceptive function of ankle joint. The therapeutic intervention of the controland experimental groups was performed a total of 20 exercise sessions, averaging 50 hour each, 5 times per week for 4 weeks. To compare the two groups, the level of ankle disability was assessed by using the ankle injury score scale in pre- and post-treatment. Results : On assessment of post-treatment, there were statistically significant differences in the scores of all sub-items, except for ankle laxity and range of motion, and the total score of ankle injury score scale between the two groups(p<0.05). In comparison between pre- and post-treatments, the significant difference in the scores of all sub-items and total score didn't appear for the control group, while the scores of most sub-items and total score of the experimental group were shown the statistically significant difference(p<0.05). Conclusion : The findings suggest that the proprioceptive exercise program is more effective for relieving ankle disability than conservative treatment therefore, the program to improve proprioceptive function should be recommended for prevention and rehabilitation of recurrent ankle inversion injuries.

• 한국가금학회지
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• 제40권4호
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• pp.369-377
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• 2013

본 실험은 육계의 서로 다른 농도의 에너지와 단백질이 생산성과 혈액성상 및 BMD에 미치는 영향을 구명하기 위하여 두 차례 실시하였다. 실험 1에서 총 480수의 Ross ${\times}$ Ross 병아리를 무작위로 6처리구(5반복; 16수/펜)로 나누어 배치하였다. 처리구는 사료 내 ME는 3,000, 3,100, 3,200 kcal/kg 수준으로 하였고 CP는 초기 22, 23%, 전기 20, 21%, 후기 18, 19% 수준으로 하였다. 실험 2에서는 실험 1과 유사하게 병아리와 CP를 적용하였으며, 사료 내 ME 수준을 변형하였다(초기 : 3,000, 3,050, 3,100 kcal/kg, 전기 : 3,050, 3,100, 3,150 kcal/kg, 후기 : 3,100, 3,150, 3,200 kcal/kg). 두 실험에서 처리구당 10수씩 혈액과 경골 샘플을 채취하였고, 혈액성상과 BMD를 분석하였다. 실험 1에서 증체량과 사료섭취량은 3,000 kcal/kg의 에너지를 급여한 처리구에서 증가되었다(P<0.05). 혈청 총 단백질과 albumin 농도는 CP의 수준이 증가함에 따라 수치적으로 증가하였다. 총 콜레스테롤과 HDL의 함유량은 에너지 함유량의 증가에 따라 수치적으로 증가하였다. 실험 2에서 증체량은 일관되게 에너지와 단백질 수준의 증가에 따라 수치적으로 증가하였다(초기 $3,000{\times}23$, 전기 $3,050{\times}21$, 후기 3,100 kcal/kg ME와 19% CP). 혈청 glucose 수준은 에너지 수준이 높아짐에 따라 증가됐다(P<0.05). 따라서 혈청 총 단백질, albumin, triglycerides, 총 콜레스테롤 그리고 HDL 함유량은 사료 에너지 증가에 따라 증가하는 경향이 있다.

• 한국대기환경학회지
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• 제4권1호
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• pp.33-44
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• 1988

For the purpose of examining the effects of simulated acid rain on the chemical properties of the experimental soil in Pinus densiflora seedlings and Forsythia koreana rooted cuttings, the experimental design of randomized block arrangement with three replications was implemented in the experimental field of Yesan National Agricultural Junior College. One-year-old Pinus densiflora seedlings and Forsythia koreana cuttings were planted in the pots filled the mixed soils (nursery soil: forest soil of siliceous sandy loam = 1 : V/V)in the early spring of 1985. The regime of artificil acid rain, in terms of spray frequency per monthly and spray amount at single treatment per plot, was simulated on the basis of climatological data averaged from 30 years records. Simulated acid rain (pH 2.0, pH4.0, and pH 5.5 as control) containing sulfuric and nitric acid in the ratio of 3:2 (chemical equivalant basis) diluted ground water, were treated on the experimental plants under condition of cutting off the natural precipitation with vinyl tunnel, during the growing season (May 1 to August 31) in 1985. THe results obtained in this study were as follows; 1. Soil acidity was dropped, and exchangeable aluminum contents in the soil was dramatically increased in both species, with decreasing pH levels of acid rain. 2. Exchangeable potassium, clacium, magnesium contents, and base saturation degree of the soil were highly drcreased in two species as the pH levels of acid rain decreased. 3. In two species, sulfate concentrations in the soil were decreased of pH 4.0 treatment, and remarkably increased at pH 2.0 treatment of acid rain in comparison with control. 4. Total nitrogen and available phosphate contents of the soil were not affected by acid rain treatment in the both species, and Fe contents at pH 2.0 treatment were highest among three acid rain treatments.

• Animal Bioscience
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• 제35권10호
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• pp.1535-1544
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• 2022

Objective: The objective of this study was to investigate the effects of decreasing dietary crude protein content on rumen fermentation, mictobiota, and metabolites in goats. Methods: In an 84-day feeding trial, a total of twelve male Anhui white goat kids with initial body weight 15.9±1.13 kg were selected and randomly classified into two groups, feeding a normal crude protein diet (14.8% CP, NCP) or a low crude protein diet (12.0% CP, LCP). At the end of the experimental trial (on day 84), six animals were randomly selected from each group and were slaughtered to collect rumen fluid samples for the analysis of rumen fermentation parameters, microbiome, and metabolome. Results: The concentrations of ammonia-nitrogen, total volatile fatty acid, acetate, and propionate were decreased (p<0.05) in the LCP group in comparison with those in the NCP group. The abundances of genera Prevotella, Campylobacter, Synergistetes, and TG5, which were associated with nitrogen metabolism, were lower (p<0.05) in the LCP group compared with those in the NCP group. The levels of 78 metabolites (74 decreased, 4 increased) in the rumen fluid were altered (p<0.05) by the treatment. Most of the ruminal metabolites that showed decreased levels in the LCP group were substrates for microbial protein synthesis. Metabolic pathway analysis showed that vitamin B6 metabolism was significantly different (p<0.05) in rumen fluid between the two treatments. Conclusion: Decreased dietary protein level inhibited rumen fermentation through microbiome and metabolome shifts in goat kids. These results enhance our understanding of ruminal bacteria and metabolites of goat fed a low protein diet.