• Smart Structures and Systems
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• 제20권2호
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• pp.231-246
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• 2017

A recent work by the authors has demonstrated the feasibility of scour evaluation for Kao-Ping-Hsi Cable-Stayed Bridge simply based on ambient vibration measurements. To further attain the goal of scour monitoring, a key challenge comes from the interference of several environmental factors that may also significantly alter the pier frequencies without the change of scour depth. Consequently, this study attempts to investigate the variation in certain modal frequencies of this bridge induced by several environmental factors. Four sets of pier vibration measurements were taken either during the season of plum rains, under regular summer days without rain, or in a period of typhoon. These signals are analyzed with the stochastic subspace identification and empirical mode decomposition techniques. The variations of the identified modal frequencies are then compared with those of the corresponding traffic load, air temperature, and water level. Comparison of the analyzed results elucidates that both the traffic load and the environmental temperature are negatively correlated with the bridge frequencies. However, the traffic load is clearly a more dominant factor to alternate the identified bridge deck frequency than the environmental temperature. The pier modes are also influenced by the passing traffic on the bridge deck, even though with a weaker correlation. In addition, the variation of air temperature follows a similar tendency as that of the passing traffic, but its effect on changing the bridge frequencies is obviously not as significant. As for the effect from the alternation of water level, it is observed that the frequency baselines of the pier modes may positively correlate with the water level during the seasons of plum rains and typhoon.

• Asian Pacific Journal of Cancer Prevention
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• 제14권7호
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• pp.4455-4457
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• 2013

In the new millennium people are facing serious challenges in health care, especially with increasing non-communicable diseases (NCD). One of the most common NCDs is cancer which is the leading cause of death in developed countries and in developing countries is the second cause of death after heart diseases. Cancer registry can make possible the analysis, comparison and development of national and international cancer strategies and planning. Information technology has a vital role in quality improvement and facility of cancer registries. With the use of IT, in addition to gaining general benefits such as monitoring rates of cancer incidence and identifying planning priorities we can also gain specific advantages such as collecting information for a lifetime, creating tele medical records, possibility of access to information by patient, patient empowerment, and decreasing medical errors. In spite of the powerful role of IT, we confront various challenges such as general problems, like privacy of the patient, and specific problems, including possibility of violating patients rights through misrepresentation, omission of human relationships, and decrease in face to face communication between doctors and patients. By implementing appropriate strategies, such as identifying authentication levels, controlling approaches, coding data, and considering technical and content standards, we can optimize the use of IT. The aim of this paper is to emphasize the need for identifying positive and negative effects of modern IT on cancer registry in general and specific aspects as an approach to cancer care management.

• 한국가금학회지
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• 제46권4호
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• pp.271-277
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• 2019

최근 산업동물에서도 동물복지의 관심이 높아짐에 따라 복지 사육방식을 채택한 농가의 수가 늘어나고 있다. 본 연구는 복지농장과 일반농장 간의 병원체 탐색 및 조류인플루엔자 방어율의 차이를 확인하고자 하였다. 복지농장 사육 육계와 산란계, 일반농장 사육 육계와 산란계에서 얻어진 샘플들을 이용하여 비교한 결과, 마이코플라즈마 검출에서는 사육형태간 차이를 확인할 수 없었으며, 저병원성 인플루엔자의 배출량도 초기를 제외하고는 차이를 확인할 수 없었다. 앞으로 국내에서 사육방식의 차이에 따른 지속적인 연구가 필요하다.

• 한국의류산업학회지
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• 제11권2호
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• pp.278-285
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• 2009

As children's apparel industry expands, there are many researches on purchasing and wearing children's clothing and optimal sizes, but researches on purchasing and wearing children's clothing and the appropriateness of sizes comparing average body shape and obese children are still inadequate. Therefore, in this research Late Elementary Schoolgirls ranging in age from 12 to 13 are categorized into the average or the obese body type, and by comparing and analyzing purchasing and wearing children's clothing and the appropriateness of its sizes between these groups, the problems in the size system of children's apparel are realized and the basic information about designing children's clothing for average body shape and non-average body shape(out-size)children are presented. The survey questions were composed of topics about general personal information, the purchasing practice and wearing practice, the appropriateness of its size when wearing children's clothing and the practice of mending apparel according to the satisfaction level of children's clothing sizes. Because subjects are often too big to wear children's clothing, and in the case of obese children the deviation of a body type is amplified, therefore in buying and wearing children's clothing, they demonstrate different forms of purchasing and wearing characteristics than adults. Considering the practice of increasing obesity in children due to westernized eating habits and decreased physical activities, along with developing programs for improving obesity, the development of an optimal size system in response to various body types will become an important challenge.

• Computers and Concrete
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• 제18권6호
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• pp.1083-1096
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• 2016

Beam-column joints are recognized as the weak points of reinforcement concrete frames. The ductility of reinforced concrete (RC) frames during severe earthquakes can be measured through the dissipation of large energy in beam-column joint. Retrofitting and rehabilitating structures through proper methods, such as carbon fiber reinforced polymer (CFRP), are required to prevent casualties that result from the collapse of earthquake-damaged structures. The main challenge of this issue is identifying the effect of CFRP on the occurrence of failure in the joint of a cross section with normal ductility. The present study evaluates the retrofitting method for a normal ductile beam-column joint using CFRP under monotonic and cyclic loads. Thus, the finite element model of a cross section with normal ductility and made of RC is developed, and CFRP is used to retrofit the joints. This study considers three beam-column joints: one with partial CFRP wrapping, one with full CFRP wrapping, and one with normal ductility. The two cases with partial and full CFRP wrapping in the beam-column joints are used to determine the effect of retrofitting with CFRP wrapping sheets on the behavior of the beam-column joint confined by such sheets. All the models are subjected to monotonic and cyclic loading. The final capacity and hysteretic results of the dynamic analysis are investigated. A comparison of the dissipation energy graphs of the three connections shows significant enhancement in the models with partial and full CFRP wrapping. An analysis of the load-displacement curves indicates that the stiffness of the specimens is enhanced by CFRP sheets. However, the models with both partial and full CFRP wrapping exhibited no considerable improvement in terms of energy dissipation and stiffness.

• Asian Pacific Journal of Cancer Prevention
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• 제13권5호
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• pp.2171-2174
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• 2012

Background: Pancreatic cancer is a distressing disease with a miserable prospects and early recognition remains a challenge due to ubiquitous symptomatic presentation, deep anatomical location, and aggressive etiology. False positives and problems in distinguishing pancreatitis from adenocarcinoma limit the use of CA 19-9 as both disorders can present with similar symptoms and share radiographic physiognomies. This study aimed to assess the relative increase in accuracy of diagnosing the patients with chronic pancreatitis, benign neoplasm of pancreas and adenocarcinomas with CA 19-9, haptoglobin, and serum amyloid A in comparison to CA 19-9 alone. Materials and Methods: This hospital based case control study was carried out in the Departments of Medicine and Biochemistry of Manipal Teaching Hospital, Pokhara, Nepal, between $1^{st}$ January 2010 and $31^{st}$ December 2011. The variables assessed were age, gender, serum CA19-9, serum haptoglobulin, serum Amyloid A. The data were analyzed using Excel 2003, R 2.8.0 Statistical Package for the Social Sciences (SPSS) for Windows Version 16.0 (SPSS Inc; Chicago, IL, USA) and the EPI Info 3.5.1 Windows Version. Results: Out of 197 cases of pancreatic disease, maximum number of assumed cases were of adenocarcinoma of pancreas (95). Number of males (59) were more than females (36) in assumed cases of adenocarcinoma of pancreas. The mean values of CA19-9 raised considerably in cases of chronic pancreatitis, benign neoplasm and adenocarcinoma of pancreas when compared to controls. The highest augmention in CA19-9 values were in cases of adenocarcinoma of pancreas. The p-value indicates that in cases of chronic pancreatitis, there was not significant increase in precision of diagnosis. Conclusions: These statistics established that haptoglobin and SAA are useful in discriminating cancer from benign conditions as well as healthy controls.

• 한국지역지리학회지
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• 제8권4호
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• pp.480-491
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• 2002

본 연구의 목적은 정보가 계약된 조건하에서의 다지역에 대한 지역간 산업연관표를 작성하고 이에 대한 정확성을 평가하는 데 있다. 지역간 산업연관표의 작성 방법은 이미 지난 1950년대 초 Isard 및 Leontief 등에 의하여 개발된 이 후 다양한 기법들이 제시되어왔다. 이들 기법 중에서 정확성 면에서는 실제 조사를 통하여 지역간 산업연관표를 작성하는 것이 가장 바람직하지만, 이 경우 많은 시간과 경비를 부담해야만 하는 현실적 어려움이 수반된다. 따라서 은 연구에서는 정보, 특히 지역수준에서 최종수요 및 지역간 상품의 흐름에 대한 정보가 제약된 조건하에서 우리나라의 전국을 5개 지역으로, 그리고 전 산업을 13개 부문으로 구분하여 비조사방법에 의하여 지역간 산업연관표를 작성하였다. 비조사방법에 의하여 지역간 산업연관표를 작성하는 방법에도 여러 가지가 있지만, 본 인구에서는 기본적인 LQ 기법을 원용하여 이를 다지역 모형으로의 확장을 시도하였다. 끝으로 추정된 투입계수의 정확성을 평가하기 위하여, 특정 지역 투자의 지역 및 지역간 파급효과를 분석하고, 이를 기존의 실제 조사를 통한 투입계수와 비교 해 보았다.

• 한국동물위생학회지
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• 제13권1호
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• pp.96-102
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• 1990

The immune responses of commercial layer chickens against Newcastle disease(ND) were compared among different administration methods and times of vaccination during 4 weeks of age. A total of 372 day-old chickens were divided into 4 groups of 93 birds each. Each of 3 groups was received a commercially available B$_1$live vaccine via drinking water, eye instillation or spray method at one, 14 and 28 days of age. One group was used as an unvaccinated control. At two and 4 weeks after each time of vaccination, 15 birds from each group were collected randomly out and challenged with virulent ND virus at the dose of $10^5E1D_{50}$ per bird. Ten to 15 birds from each group were bled at two weeks intervals from day old to 8 weeks of age for hemagglutination inhibition antibody titer, The protection rate was generally low regardless of the times of vaccination although two or more times vaccination gave higher protection than once vaccination. The low protection was considered due to low titer of the vaccine used since the vaccine titer was less than $10^{3.5}EID_{50}$ per bird. Spray method gave better protection compared to eye instillation or drinking water method which resulted in lowest response. Majority of birds showed clinical signs of ND between 3 and 6 days after challenge. Death occured one or two days after onset of symptoms. Major clinical signs observed were depression(94%), anorexia(84%), diarrhoea(29%), difficult breath(15%) and torticollis(10%). Hemorrhagic lesions on post mortem were seen in duodenum(51%), trachea(35%), illeum(13%), ceacal tonsil(11%), proventriculus(10%) and some other odrgans.

• Biomolecules & Therapeutics
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• 제23권5호
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• pp.449-457
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• 2015

The present study was aimed to investigate the effects of MB12662, a synthetic dunnione compound, on cisplatin-induced vomiting reflexes and intestinal, renal, immune system, and hematopoietic toxicities in ferrets and mice, respectively. Male ICR mice were orally administered MB12662 (5, 10, 25 or 50 mg/kg) for 10 days, during which intraperitoneally challenged with cisplatin (3.5 mg/kg) from day 4 to 7, and sacrificed on day 10 for the pathological examination. Male ferrets were orally administered MB12662 (25, 50 or 100 mg/kg) for 7 days, subcutaneously challenged with cisplatin (5 mg/kg), and monitored for vomiting reflexes and survival of the animals. Four-day injection of cisplatin (3.5 mg/kg) to mice caused body weight loss and degeneration and atrophy of intestinal villi, reducing villi/crypt ratio to a half level of control animals. Cisplatin also induced renal and hepatic toxicities, and depletion of splenocytes and bone marrow progenitor cells. The systemic toxicities including decreased villi/crypt ratio, immune system atrophy, splenocyte depletion, and decreased cellularity in bone marrow were improved by MB12662. Cisplatin (5 mg/kg) induced retching and emetic responses of ferrets, which were remarkably attenuated by MB12662 in a dose-dependent manner. All the ferrets pretreated with MB12662 survived the challenge of cisplatin, in comparison with 40% mortality in vehicle-treated animals, and blood parameters of nephrotoxicity and hepatotoxicity were markedly recovered. It is expected that MB12662 could be a candidate for the body protection against burden, including emesis, of chemotherapeutic agents.

• 한국산학기술학회논문지
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• 제13권5호
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• pp.1954-1962
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• 2012

최근 유럽과 아시아 사이의 물류 증가는 철도수송에 있어서 사회적/경제적으로 좋은 기회이며, 동시에 커다란 도전이 될 수 있다. 유라시아 대륙에는 다양한 궤간이 존재하고 있다. 이러한 궤간의 차이는 철도에 의한 화물수송시 장애요인중의 하나이다. 궤간 차이를 극복하기 위한 방법은 수송 화물의 유형에 따라 달라질 수 있으며, 국경 지점에 보관 창고 및 환적 설비와 같은 넓은 기반 시설과 많은 운영 인력수요와 같은 철도 수송 시스템의 운영에 많은 영향을 준다. 따라서 철도 수송 시스템의 효율성은 복잡한 하역 및 교환 기술에 관련된 궤간 극복 방법에 매우 의존한다. 본 논문은 궤간 극복 방법에 대한 기술적 평가를 기반으로 수송 시나리오의 효율성을 검토하고, 각 시나리오의 운영에서 요구되는 기술적 요소들을 기술하였다.