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Experimental Study on the Effect of Jeongkicheonhyangtang and Kamijeongkicheonhyangtang (정기천향탕(正氣天香湯) 및 가미정기천향탕(加味正氣天香湯)의 효능(效能)에 대한 실험적(實驗的) 연구(硏究))

  • Park, Chan-Ki;Kwon, Jung-Nam;Kim, Young-Kyun
    • Korean Journal of Oriental Medicine
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    • v.3 no.1
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    • pp.241-260
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    • 1997
  • Effect of Jeongkicheonhyangtang and Kamijeongkicheonhyangtang have been experimentally studied. The results have been obtained as follows : 1. It is proved that analgecic effect on sample I group and sample II group are clearly decreased than control group. Thus, the statistically significant decrease is p<0.005. 2. It is proved that anti-inflammatory effect on sample I group and sample II group are decreased compare to control group. Thus, the statistically significant decrease of sample I group is p<0.05 in 30 and 60-minute, p<0.01 in 90-minute, and p<0.005 in 120 and 180-minute. And those of sample ll group is p<0.05 in 30 and 60-minute and p<0.005 in 90, 120 and 180-minute. 3. It is proved that appearance of gastric ulcer is decreased compare to the control group and the statistically significant decrease is p<0.05. 4. It is proved that plasma epinephrine contents of sample I and II group are clearly decreased compare to the Control Group and the statistically significant decrease is p<0.005. 5. It is proved that plasma norepinephrine contents of sample I group is drastically decreased compare to the control group and the statistically significant decrease is p<0.005. 6. It is proved that plasma dopamine contents of sample I and II group are decreased than the contort group and statistically significant decrease of the sample I group is p<0.005, and those of the sample II group is p<0.05. As the above mentioned results of experiment, It is belived that Jeongklcheonhyang and Kamijeongkicheonhyang have effect for stress.

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Experimental study on the effect of low energy laser irradiation in Langerhans cell of Lanaged rat oral mucosa (저출력 레이저 조사 백서구강점막 창상부 Langerhans 세포에 미치는 영향에 관한 실험적 연구)

  • Cho, Jae-O;Hanks, Carl T.
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.15 no.3
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    • pp.217-228
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    • 1993
  • The purpose or this study was to observe the histological alteration of Langerhans cells on wound healing process in applying low energy laser irradiation. For this study, 50 Spraque-Dewly rats, weighing 150Gm or more were devided into control, experimental control group(0), 47.5Hz(1), 190Hz(3), 380Hz(5), 760Hz(7), lased group. All the experimental animals were made excision wound on buccal mucosa, 2mm depth, and lased with stoma laser (904nm, semconductor type ASGaAI, Sedalac France) 47.5Hz, 380Hz, 960Hz, 3minutes one time respectively except experimental control group. After the experiment, experimental animals were sacrificed after 24hours, 48hours, 72hours on each. Taken specimens were embedden in paraffin, sectioned 6-8u in thickness. And the langerhans cell were detected using ant S-100 protein antibody, and histochemically processed with Avidin Biotin complex method. All the Langerhan cells were calculated under light microspe in 400 multiplication field and standard deviation, probability test between each group were evaluated using statistical analysis system(S.A.S)program. Following results were obtained. 1. Langerhan cells were increased in experimental control group compared to that in control group(P<0.01). 2. 24hour after experiments, Langerhans cell were decreased compare to that in control group and control experimental group 5, 1, 3. Probability test shows significance between control experimental and 5, 1, 3 group on a =0.05 range. 3. 48our after experiment, Langerhans cells were decreased compare to that on experimental control group, and probability test shows significance between control experimental and 3, 7, 5 group an a=0.05 range. 4. 72hour after experiments, Langerhans cells were decreased compare to that on experimental control group and probability test on group comparison shows significance between control experimental and 1, 5 and 1 between 3, 7 between 3, and 5, between 7, respeilively on a=0.05 range. 5. Langerhans cells number in experimental group were decreased compare to that on experimental control group in applying laser irradiation.

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A Phase III, Randomized, Multi-Center, Double-Masked, Matched-Pairs, Active-Controlled Trial to Compare the Efficacy and Safety between Neuramis Deep and Restylane in the Correction of Nasolabial Folds

  • Pak, Changsik;Park, Jihoon;Hong, Jinmyung;Jeong, Jaehoon;Bang, Saik;Heo, Chan Yeong
    • Archives of Plastic Surgery
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    • v.42 no.6
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    • pp.721-728
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    • 2015
  • Background We conducted this clinical study to compare the efficacy and safety between Neuramis Deep and Restylane in the correction of nasolabial folds. Methods In this phase III, randomized, multi-center, double-masked, matched-pairs, active-controlled trial (ClinicalTrials.gov Identifier: NCT01585220), we evaluated a total of 67 subjects (n=67). All the subjects underwent Neuramis Deep treatment on one side and Restylane on the contralateral side of the bilateral nasolabial folds at a ratio of 1:1. To compare the efficacy of Neuramis Deep and Restylane, we evaluated the Wrinkle Severity Rating Scale scores and those of the Global Aesthetic Improvement Scale. In addition, we compared the safety of Neuramis Deep and Restylane based on adverse events, physical examination, and clinical laboratory tests. Results Neuramis Deep was not inferior in improving the nasolabial folds as compared with Restylane. In addition, there was no significant difference in the efficacy between Neuramis Deep and Restylane. There were no significant differences in safety parameters between Neuramis Deep and Restylane. Conclusions In conclusion, our results indicate that Neuramis Deep may be a safe, effective material for improving the nasolabial folds. However, further studies are warranted to compare the tolerability of Neuramis Deep and Restylane based on histopathologic findings.

A CEPHALOMETRIC STUDY OF KOREAN CHILDREN BY RICKETTS' ANALYSIS (리켓츠 분석을 이용한 한국인 아동의 두부방사선 계측학적 연구)

  • Yang, Kyu-Ho;Kim, Seon-Mi
    • Journal of the korean academy of Pediatric Dentistry
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    • v.25 no.2
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    • pp.430-440
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    • 1998
  • This study was performed to establish the cephalometric standards and to compare measurement of Korean children in the Field I, II, III, IV, V, VI to Japanese and Caucasians by the Ricketts' analysis. Lateral cephalograms of 24 males and 27 females with normal occlusion and acceptable profile 9 years of age were obtained and statistically analyzed. 1. Norms of Korean males, females and both sexes at 9 years old were established. 2. Significant differences between male and female exist in incisor overjet, maxillary incisor protrusion, mandibular incisor inclination, cranial deflection, corpus length. Maxillary incisor of male was more protrude and overjet was larger than female 3. Korean was similar to Japanese but different from Caucasian. Compare with facial axis and facial depth, chin was retruded dolichofacial pattern and due to large mandibular plane angle and small corpus length, mandibular plane was inclined and mandible body was short. Compare with porion location, ramus position and posterior facial height, ramus was long and located posterior. Compare with maxillary depth and maxillary height, maxilla was located posterior and inferior. The distance between the upper molar and PTV was short, the amount of distalization is limited. Maxillary and mandibular incisor were more protruded and also lower lip was more protruded to esthetic line 4. In comparison between 9 and 11 years old, growth changes of facial depth, mandibular plane angle, corpus length and upper molar position were larger than that of Japanese and Caucasians.

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Comparisons of Airline Service Quality Using Social Network Analysis (소셜 네트워크 분석을 활용한 항공서비스 품질 비교)

  • Park, Ju-Hyeon;Lee, Hyun Cheol
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.42 no.3
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    • pp.116-130
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    • 2019
  • This study investigates passenger-authored online reviews of airline services using social network analysis to compare the differences in customer perceptions between full service carriers (FSCs) and low cost carriers (LCCs). While deriving words with high frequency and weight matrix based on the text analysis for FSCs and LCCs respectively, we analyze the semantic network (betweenness centrality, eigenvector centrality, degree centrality) to compare the degree of connection between words in online reviews of each airline types using the social network analysis. Then we compare the words with high frequency and the connection degree to gauge their influences in the network. Moreover, we group eight clusters for FSCs and LCCs using the convergence of iterated correlations (CONCOR) analysis. Using the resultant clusters, we match the clusters to dimensions of two types of service quality models ($Gr{\ddot{o}}nroos$, Brady & Cronin (B&C)) to compare the airline service quality and determine which model fits better. From the semantic network analysis, FSCs are mainly related to inflight service words and LCCs are primarily related to the ground service words. The CONCOR analysis reveals that FSCs are mainly related to the dimension of outcome quality in $Gr{\ddot{o}}nroos$ model, but evenly distributed to the dimensions in B&C model. On the other hand, LCCs are primarily related to the dimensions of process quality in both $Gr{\ddot{o}}nroos$ and B&C models. From the CONCOR analysis, we also observe that B&C model fits better than $Gr{\ddot{o}}nroos$ model for the airline service because the former model can capture passenger perceptions more specifically than the latter model can.

Development of a New Similarity Index to Compare Time-series Profile Data for Animal and Human Experiments (동물 및 임상 시험의 시계열 프로파일 데이터 비교를 위한 유사성 지수 개발)

  • Lee, Ye Gyoung;Lee, Hyun Jeong;Jang, Hyeon Ae;Shin, Sangmun
    • Journal of Korean Society for Quality Management
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    • v.49 no.2
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    • pp.145-159
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    • 2021
  • Purpose: A statistical similarity evaluation to compare pharmacokinetics(PK) profile data between nonclinical and clinical experiments has become a significant issue on many drug development processes. This study proposes a new similarity index by considering important parameters, such as the area under the curve(AUC) and the time-series profile of various PK data. Methods: In this study, a new profile similarity index(PSI) by using the concept of a process capability index(Cp) is proposed in order to investigate the most similar animal PK profile compared to the target(i.e., Human PK profile). The proposed PSI can be calculated geometric and arithmetic means of all short term similarity indices at all time points on time-series both animal and human PK data. Designed simulation approaches are demonstrated for a verification purpose. Results: Two different simulation studies are conducted by considering three variances(i.e., small, medium, and large variances) as well as three different characteristic types(smaller the better, larger the better, nominal the best). By using the proposed PSI, the most similar animal PK profile compare to the target human PK profile can be obtained in the simulation studies. In addition, a case study represents differentiated results compare to existing simple statistical analysis methods(i.e., root mean squared error and quality loss). Conclusion: The proposed PSI can effectively estimate the level of similarity between animal, human PK profiles. By using these PSI results, we can reduce the number of animal experiments because we only focus on the significant animal representing a high PSI value.

A Study on Design and Development of Web Information Collection System Based Compare and Merge Method (웹 페이지 비교통합 기반의 정보 수집 시스템 설계 및 개발에 대한 연구)

  • Jang, Jin-Wook
    • Journal of Information Technology Services
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    • v.13 no.1
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    • pp.147-159
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    • 2014
  • Recently, the quantity of information that is accessible from the Internet is being dramatically increased. Searching the Web for useful information has therefore become increasingly difficult. Thus, much research has been done on web robots which perform internet information filtering based on user interest. If a web site which users want to visit is found, its content is searched by following the searching list or Web sites links in order. This search process takes a long time according as the number of page or site increases so that its performance need to be improved. In order to minimize unnecessary search with web robots, this paper proposes an efficient information collection system based on compare and merge method. In the proposed system, a web robot initially collects information from web sites which users register. From the next visit to the web sites, the web robot compares what it collected with what the web sites have currently. If they are different, the web robot updates what it collected. Only updated web page information is classified according to subject and provided to users so that users can access the updated information quickly.

A Study on the Comparison of Illuminance Simulations and Measured Values of Compare a Stage and Broadcasting Lighting Fixture (무대방송 조명 등기구에서의 조도 실측과 시뮬레이션 조도 측정 비교 연구)

  • Lee, Jang-Weon;Im, Jee-Weon;Han, Seok-Woo
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.11 no.2
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    • pp.145-152
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    • 2011
  • Stage-broadcasting Fresnel and Plano Convex Lighting fixture were fabricated. Compare illumination simulation and measured values for Fresnel and Plano Convex fixture. After made Lighting install studio motor system construction. In studio Daejeon Health Sciences College we measured illuminance and simulation in order to compare Fresnel and Plano Convex Lighting. And we study how much different illuminance between Fresnel and Plano Convex Lighting. In the result of comparison of simulation Fresnel and Plano Convex Lighting fixture are measures of difference value 39.7~250.6Lux and comparison of actually Fresnel and Plano Convex Lighting fixture are measure of difference value 92.84~157.35Lux.

A Study on Manifest Needs of the Patient with Hyperthyroidism (갑상선 기능항진증 환자의 욕구구조에 관한 연구)

  • 최영희;강익화
    • Journal of Korean Academy of Nursing
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    • v.11 no.2
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    • pp.69-82
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    • 1981
  • The purpose of this study was to compare the needs among the patients of hyperthyroid, malignant tumor and normal adult to clarify the level of the need for the patient of hyperthyroid. We analysed relationships between their personal characteristics and their needs to contribute comprehensive nursing care for the patient of hyperthyroid. The . subjects were chosen from 60 persons who visited for general physical examination at Ewha Woman's University Medical Center., 72 patients having diagnosis with hyperthyroidism, and 72 patients admitted with malignant tumors at atomic neuclear medical center. The data was collected from September 1 to December 31, 1980, and the study population was selected by means of convenience sampling. The data was analysed by means of the standard deviation and analysis of variance. The results were as follows: 1. In the patients having hyperthyroid, male to female ratio was 1 :13.5, and incidence was peak at the age groups of 20 to 40. 2. In compare with the needs among 3 groups, there are significant relationships: the patient of cancer has shown the highest score with Achievement, Aggression and Dominance, the patient of hyperthyroid shown higher and the normal adult shown low score. .In the need related with sex, there is significant relationship: the normal adult has shown highest score, the patient having hyperthyroid shown the higher score and the patient of cancer shown the low score. 3. Tn compare with Whang's Edward personal preference schedule, the Hyperthyroidism shown relatively higher needs for aggression, dominance, exhibitionism and sex.

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Cryoanalgesia vs Bupivacain Intercostal Nerve Block for the Post -thoracotomy Pain (개흉술 후 흉부동통억제를 위한 늑간신경냉동 요법과 약물주입요법에 관한 비교연구)

  • 최영호
    • Journal of Chest Surgery
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    • v.27 no.11
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    • pp.942-947
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    • 1994
  • Post-thoracotomy pain is so severe that lead to postoperative pulmonary complications due to the patient`s inability to cough, deep breathing and chest wall motion. Many authors have been trying to reduce the post-thoracotomy pain, but there is no method of complete satisfaction. In 1990, we reported the result that the cryoanalgesia reduce the immediate postoperative pain significantly. We try to compare the effect of cyroanalgesia with the effect of Bupivacain intercostal nerve block for the post-thoracotomy pain control. Ninety patients, who undergoing thoracotomy in Korea University Medical Center Guro Hospital between the January 1993 and September 1993, were evaluated. The patients were divided into three groups : Group A, control, the patients without pain control procedure [N=30], Group B, the patients with Bupivacain intercostal nerve block [N=30], Group C, the patients with cryoanalgesia [N=30]. Postoperative analgesic effects were evaluated by the scoring system which made arbiturary by author. The results were that the Bupivacain intercostal nerve block markedly reduced the immediate postoperative pain compare with two other groups, the cryoanalgesia reduced the immediate postoperative pain significantly compare with control group, the pain reduction effect of the two groups- cryoanalgesia and Bupivacain intercostal nerve block- were not different at postoperative seventh day, probably due to the action time of Bupivacain and the result that there were no significant complications of the procedures.

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