• Title/Summary/Keyword: Comparative Research

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Functional Genomic Approaches Using the Nematode Caenorhabditis elegans as a Model System

  • Lee, Jun-Ho;Nam, Seung-Hee;Hwang, Soon-Baek;Hong, Min-Gi;Kwon, Jae-Young;Joeng, Kyu-Sang;Im, Seol-Hee;Shim, Ji-Won;Park, Moon-Cheol
    • BMB Reports
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    • v.37 no.1
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    • pp.107-113
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    • 2004
  • Since the completion of the genome project of the nematode C. elegans in 1998, functional genomic approaches have been applied to elucidate the gene and protein networks in this model organism. The recent completion of the whole genome of C. briggsae, a close sister species of C. elegans, now makes it possible to employ the comparative genomic approaches for identifying regulatory mechanisms that are conserved in these species and to make more precise annotation of the predicted genes. RNA interference (RNAi) screenings in C. elegans have been performed to screen the whole genome for the genes whose mutations give rise to specific phenotypes of interest. RNAi screens can also be used to identify genes that act genetically together with a gene of interest. Microarray experiments have been very useful in identifying genes that exhibit co-regulated expression profiles in given genetic or environmental conditions. Proteomic approaches also can be applied to the nematode, just as in other species whose genomes are known. With all these functional genomic tools, genetics will still remain an important tool for gene function studies in the post genome era. New breakthroughs in C. elegans biology, such as establishing a feasible gene knockout method, immortalized cell lines, or identifying viruses that can be used as vectors for introducing exogenous gene constructs into the worms, will augment the usage of this small organism for genome-wide biology.

A Bibliometric Approach for Department-Level Disciplinary Analysis and Science Mapping of Research Output Using Multiple Classification Schemes

  • Gautam, Pitambar
    • Journal of Contemporary Eastern Asia
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    • v.18 no.1
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    • pp.7-29
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    • 2019
  • This study describes an approach for comparative bibliometric analysis of scientific publications related to (i) individual or several departments comprising a university, and (ii) broader integrated subject areas using multiple disciplinary schemes. It uses a custom dataset of scientific publications (ca. 15,000 articles and reviews, published during 2009-2013, and recorded in the Web of Science Core Collections) with author affiliations to the research departments, dedicated to science, technology, engineering, mathematics, and medicine (STEMM), of a comprehensive university. The dataset was subjected, at first, to the department level and discipline level analyses using the newly available KAKEN-L3 classification (based on MEXT/JSPS Grants-in-Aid system), hierarchical clustering, correspondence analysis to decipher the major departmental and disciplinary clusters, and visualization of the department-discipline relationships using two-dimensional stacked bar diagrams. The next step involved the creation of subsets covering integrated subject areas and a comparative analysis of departmental contributions to a specific area (medical, health and life science) using several disciplinary schemes: Essential Science Indicators (ESI) 22 research fields, SCOPUS 27 subject areas, OECD Frascati 38 subordinate research fields, and KAKEN-L3 66 subject categories. To illustrate the effective use of the science mapping techniques, the same subset for medical, health and life science area was subjected to network analyses for co-occurrences of keywords, bibliographic coupling of the publication sources, and co-citation of sources in the reference lists. The science mapping approach demonstrates the ways to extract information on the prolific research themes, the most frequently used journals for publishing research findings, and the knowledge base underlying the research activities covered by the publications concerned.

COMPARATIVE STUDY ON PANEER MAKING FROM BUFFALO AND COW MILK

  • Masud, T.;Athar, I.H.;Shah, M.A.
    • Asian-Australasian Journal of Animal Sciences
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    • v.5 no.3
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    • pp.563-565
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    • 1992
  • The objective of this study is to compare the qualitative and quantitative properties of paneer prepared from buffalo and cow milk. Paneer from buffalo milk had higher total solids as compared to cow. Moreover significant differences were recorded in fat and protein contents among tested samples of milk, cheese and whey respectively. The results of the organoleptic evaluations showed that paneer made from cow milk was liked more as compared to buffalo.

Comprehensive Comparative Assessment of National Energy and Power Systems

  • Kim, Tae-Woon;Ha, J.J.;Lee, Sung-Jin;Chang, Soon-H.;Kim, Seong-Ho
    • Proceedings of the Korean Nuclear Society Conference
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    • 2004.10a
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    • pp.1459-1460
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    • 2004
  • An AHP-based framework for comprehensive comparison of several power technologies haas been developed. A questionnaire has been designed and is about to surveyed for extracting boty weight vectors and subjective evaluation values. The attitude of evaluator groups will be incorporated into these two types of quantification.

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A Study on Jamokai(子母蓋) (子母蓋의 硏究)

  • 김진구
    • The Research Journal of the Costume Culture
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    • v.5 no.1
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    • pp.11-18
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    • 1997
  • The purpose of this research was to ideatify and to trace the origin and meaning of jamokai(子母蓋). Comparative linguistic analytical approaches were used for the analysis of this study. Summaries of findings in this research are as follows : 1. There wese a number of phonetic value for jamokai (子母蓋) in Chinese. 2. The term, jamokai was derived from Hebrew. 3. The meaning of jamokai of Koryo was originated from Hebrew word meaning woman's veil. 4. The word jamokai was related to Perian, Arakic, Indian. 5. It is considered that tsi-ma-kai (치마개) was transliterated to tsi-m∂u-kai (子母蓋) in Chinese by the author of Keirim Yusa (鷄林類事). 6. The word jamokai (子母蓋) of Koryo was not related to Chinese.

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Comparative Enzyme Production by Fungi from Diverse Lignocellulosic Substrates

  • Sin, Marie K.W.;Hyde, Kevin D.;Pointing, Stephen B.
    • Journal of Microbiology
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    • v.40 no.3
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    • pp.241-244
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    • 2002
  • Fungi commonly encountered on monocotyledonous substrates were evaluated for their in vitro ability to produce enzymes involved in lignocellulose breakdown. Most were capable of structural polysac-charide utilization, but few produced enzymes associated with lignin breakdown. None of the mono-cotyledon-inhabiting fungi produced reactions as strongly as wood decay fungi.

Comparative Genomics of Vibrio cholerae

  • Chun, Jong-Sik;Jeon, Yoon-Seong;Lee, Je-Hee;Choi, Seon-Young;Kim, Dong-Wook;Grim, Christopher J.;Hasan, Nur A.;Colwell, Rita R.
    • Proceedings of the Microbiological Society of Korea Conference
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    • 2009.05a
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    • pp.57-57
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    • 2009
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