• Title/Summary/Keyword: Common Source line

Search Result 66, Processing Time 0.02 seconds

Serotyping in Patients with Chronic Hepatitis C

  • Soon-Mo Chang
    • Biomedical Science Letters
    • /
    • v.9 no.4
    • /
    • pp.209-214
    • /
    • 2003
  • To determine the clinical usefulness of Immuno Blot test, 160 samples from the patients with chronic HCV infection were analyzed. And serotyping and line probe assay were performed to evaluate the distribution of hepatitis C virus genotypes in Korean isolates. In this group, as a result of genotyping type 1 band 2a, the serotype I and II were the most common source of HCV infection. There were no significant difference in response to the alpha-interferon HCV infection treatment with the subtype 1 b or 2a. And the serotypes of NS4 peptides were compared with the genotypes to evaluate their clinical usefulness. Among 49 cases studied for genotypes and serotype, genotype 1 b, 1 b/2b, 2a, 2a/2c and 2b were 51.0%, 2.0%, 34.6%, 8.1% and 4.0%, respectively. The serotypes I and II were 57.1% and 42.8%, respectively; they were matched with genotypes in 85.7% and seemed to be easy to perform. To monitor their performing progress or treatment response, serotype test was made before the genotype test. The Result showed that there was no significant difference in response to the alpha-interferon HCV infection treatment with the subtype 1 b or 2a in Korea.

  • PDF

Establishment and Verification of SPT-uphole method for Evaluating Shearwave Velocity of a site (지반의 전단파 속도 도출을 위한 SPT 업홀 기법의 확립 및 검증)

  • Bang, Eun-Seok;Kim, Jung-Ho;Seo, Won-Seok;Kim, Dong-Soo
    • Proceedings of the Korean Geotechical Society Conference
    • /
    • 2008.03a
    • /
    • pp.142-152
    • /
    • 2008
  • SPT-Uphole method was introduced for the evaluation of near subsurface shear wave velocity (Vs) profile. In SPT-Uphole method, SPT (Standard Penetration Test) which is common in geotechnical site investigation was used as a source and several surface geophones in line were used as receivers. 1D shearwave velocity profile can be obtained in the manner of downhole method, Vs distribution map which is the triangular shape around the boring point can be developed by tomography inversion. To obtain the exact travel time information of shear wave component, a procedure using the magnitude summation of vertical and horizontal components was used based on the evaluation of particle motion at the surface. It was verified that proposed method could give reliable Vs distribution map through the numerical study using the FEM (Finite Element Method) model. Finally, SPT-Uphole method was performed and the feasibility of proposed method was verified in the field.

  • PDF

A 77 GHz 3-Stage Low Noise Amplifier with Cascode Structure Utilizing Positive Feedback Network using 0.13 μm CMOS Process

  • Lee, Choong-Hee;Choi, Woo-Yeol;Kim, Ji-Hoon;Kwon, Young-Woo
    • JSTS:Journal of Semiconductor Technology and Science
    • /
    • v.8 no.4
    • /
    • pp.289-294
    • /
    • 2008
  • A 77 GHz 3-stage low noise amplifier (LNA) employing one common source and two cascode stages is developed using $0.13{\mu}m$ CMOS process. To compensate for the low gain which is caused by lossy silicon substrate and parasitic element of CMOS transistor, positive feedback technique using parasitic inductance of bypass capacitor is adopted to cascode stages. The developed LNA shows gain of 7.2 dB, Sl1 of -16.5 dB and S22 of -19.8 dB at 77 GHz. The return loss bandwidth of LNA is 71.6 to 80.9 GHz (12%). The die size is as small as $0.7mm\times0.8mm$ by using bias line as inter-stage matching networks. This LNA shows possibility of 77 GHz automotive RADAR system using $0.13{\mu}m$ CMOS process, which has advantage in cost compared to sub-100 nm CMOS process.

Effects of MeOH Extract of Impatiens balsamina L. on the Metabolism of Amyloid Precursor Protein in Neuroblastoma Cells (봉선화 전초의 메탄올 추출물이 신경세포에서 아밀로이드 전구단백질의 대사에 미치는 영향)

  • Jo, Yoon Jeong;Leem, Jae Yoon
    • Korean Journal of Pharmacognosy
    • /
    • v.46 no.1
    • /
    • pp.72-77
    • /
    • 2015
  • One of the most common forms of dementia, Alzheimer's disease (AD) is a progressive neurodegenerative disorder symptomatically characterized by impairment in memory and cognitive abilities. AD is characterized pathologically by the presence of intracellular neurofibrillary tangles and deposition of ${\beta}$-amyloid ($A{\beta}$) peptides, believed to be neurotoxic and now is also considered to have a role on the mechanism of memory dysfunction. In this study, we tested that MeOH extract of Impatiens balsamina L. (IBM) affects on the processing of APP from the APPswe over-expressing Neuro2a cell line. We found that IBM increased over 2 folds of the $sAPP{\alpha}$ secretion level, a main metabolite of ${\alpha}$-secretase. We shown that IBM reduced the secretion level of $A{\beta}42$ and $A{\beta}40$ without cytotoxicity. BACE (${\beta}$-site APP cleaving enzyme) FRET assay shown that BACE activity was specifically decreased in the presence of IBM. We suggest that Impatiens balsamina L. may be an useful source to develop a herbal medicine of BACE inhibitor for Alzheimer's disease.

Scarf Design with Application of the Pangudae Petroglyph (반구대 암각화를 응용한 스카프 디자인 연구)

  • Kim, Jong-Soon;Jang, Jeong-Dae
    • Fashion & Textile Research Journal
    • /
    • v.9 no.3
    • /
    • pp.262-269
    • /
    • 2007
  • Traces of ancestors in the era without letters can be found in their legacies and remains such as stone implement, earthenware, dwelling sites, etc. Petroglyph among them reflects their life and spirits as like an epic so that we can be with them through petroglyph. petroglyph is a common culture of mankind, which has been found in various places over the world. The infinite value of traditional culture has a great impact as much as it is unnecessary to more discuss about it. When a culture of a country is reproduced as a world-class product, the country can have visible profits as well as positive effects on diverse fields. The Pangudae petroglyph in Ulsan, consistion of fishery and huntihg religiong, is one of the greatest cultural legacies of the local own uniqueness, and a source and thesaurus of design development. Despite limited tools and unskilled tact, the Pangudae petroglyph Carving shows a strong vital power, which does not change by time, of a whale or a man with various methods such as line and face carving, embossed carving, etc. under a desperate and unconditional purpose, the survival. Thus, the study tries to suggest scarf designs that applies such beauty in fashion design by using the formative beauty caused by natural abrasion through the time, and the feel of lines and stony material.

High Efficiency AC-DC Converter Using Average-Current Mode Flyback Topology for PDP and Improvement of Hold-up Characteristic (평균전류모드 플라이백 토폴로지를 이용한 PDP용 고효율 AC-DC 컨버터 및 Hold-up 특성 개선)

  • Lee, Kyung-In;Lim, Seung-Beom;Jung, Yong-Min;Oh, Eun-Tae;Lee, Jun-Young
    • Journal of the Semiconductor & Display Technology
    • /
    • v.7 no.2
    • /
    • pp.23-27
    • /
    • 2008
  • Recently, regulation for THD (Total Harmonic Distortion) such as IEC 61000-3-2, IEEE 519 is being reinforced about a product which directly connects to AC line in order to prevent distortion of common power source in electronic equipment and electrical machinery. In order to satisfy these regulations, conventional circuits were used two-stage structure attached power factor correction circuit at ahead of converter but this method complicate the circuit and then a number of element increases thereupon the cost of production rises. in this paper, we propose a high efficiency single-stage 300W PFC fly-back converter that improved power factor and efficiency than conventional two-stage power module.

  • PDF

A Zero Sequence Voltage Injection Method for Cascaded H-bridge D-STATCOM

  • Yarlagadda, Srinivasa Rao;Pathak, Mukesh Kumar
    • Journal of Power Electronics
    • /
    • v.17 no.4
    • /
    • pp.1088-1096
    • /
    • 2017
  • Load variations on a distribution line result in voltage fluctuations at the point of common coupling (PCC). In order to keep the magnitude of the PCC voltage constant at its rated value and obtain zero voltage regulation (ZVR), a D-STATCOM is installed for voltage correction. Moreover, the ZVR mode of a D-STATCOM can also be used to balance the source current during unbalanced loading. For medium voltage and high power applications, a D-STATCOM is realized by the cascaded H-bridge topology. In the ZVR mode, the D-STATCOM may draw unbalanced current and in this process is required to handle different phase powers leading to deviations in the cluster voltages. Zero sequence voltage needs to be injected for ZVR mode, which creates circulating power among the phases of the D-STATCOM. The computed zero sequence voltage and the individual DC capacitor balancing controller help the DC cluster voltage follow the reference voltage. The effectiveness of the control scheme is verified by modeling the system in MATLAB/SIMULINK. The obtained simulations are further validated by the experimental results using a dSPACE DS1106 and five-level D-STATCOM experimental set up.

Cucurbit Powdery Mildew: First Insights for the Identification of the Causal Agent and Screening for Resistance of Squash Genotypes (Cucurbita moschata (Duchesne ex Lam.) Duchesne ex Poir.) in Mendoza, Argentina

  • Caligiore-Gei, Pablo Fernando;Della-Gaspera, Pedro;Benitez, Eliana;Tarnowski, Christian
    • The Plant Pathology Journal
    • /
    • v.38 no.4
    • /
    • pp.296-303
    • /
    • 2022
  • The cucurbit powdery mildew (CPM) caused by different fungal species is a major concern for cucurbit crops around the world. In Argentina CPM constitutes the most common and damaging disease for cucurbits, especially for squash crops (Cucurbita moschata). The present study displays initial insights into the knowledge of the disease in western Argentina, including the determination of the prevalent species causing CPM, as well as the evaluation of the resistance of squash cultivars and breeding lines. Fungal colonies were isolated from samples collected in Mendoza province, Argentina. A field trial was also performed to assess the resistance of five squash accessions, including commercial cultivars and breeding lines. The severity of CPM was analyzed and epidemiological models were built based on empirical data. The morphological determinations and analysis with specific molecular markers confirmed Podosphaera xanthi as the prevalent causal agent of CPM in Mendoza. The results od the field trial showed differences in the resistance trait among the squash accessions. The advanced breeding line BL717/1 showed promising results as source of CPM resistance for the future development of open pollinated resistant cultivars, a crucial tool for an integrative control of the disease.

A Ripple Rejection Inherited RPWM for VSI Working with Fluctuating DC Link Voltage

  • Jarin, T.;Subburaj, P.;Bright, Shibu J V
    • Journal of Electrical Engineering and Technology
    • /
    • v.10 no.5
    • /
    • pp.2018-2030
    • /
    • 2015
  • A two stage ac drive configuration consisting of a single-phase line commutated rectifier and a three-phase voltage source inverter (VSI) is very common in low and medium power applications. The deterministic pulse width modulation (PWM) methods like sinusoidal PWM (SPWM) could not be considered as an ideal choice for modern drives since they result mechanical vibration and acoustic noise, and limit the application scope. This is due to the incapability of the deterministic PWM strategies in sprawling the harmonic power. The random PWM (RPWM) approaches could solve this issue by creating continuous harmonic profile instead of discrete clusters of dominant harmonics. Insufficient filtering at dc link results in the amplitude distortion of the input dc voltage to the VSI and has the most significant impact on the spectral errors (difference between theoretical and practical spectra). It is obvious that the sprawling effect of RPWM undoubtedly influenced by input fluctuation and the discrete harmonic clusters may reappear. The influence of dc link fluctuation on harmonics and their spreading effect in the VSI remains invalidated. A case study is done with four different filter capacitor values in this paper and results are compared with the constant dc input operation. This paper also proposes an ingenious RPWM, a ripple dosed sinusoidal reference-random carrier PWM (RDSRRCPWM), which has the innate capacity of suppressing the effect of input fluctuation in the output than the other modern PWM methods. MATLAB based simulation study reveals the fundamental component, total harmonic distortion (THD) and harmonic spread factor (HSF) for various modulation indices. The non-ideal dc link is managed well with the developed RDSRRCPWM applied to the VSI and tested in a proto type VSI using the field programmable gate array (FPGA).

Comparative Study of Minimum Ripple Switching Loss PWM Hybrid Sequences for Two-level VSI Drives

  • Vivek, G.;Biswas, Jayanta;Nair, Meenu D.;Barai, Mukti
    • Journal of Power Electronics
    • /
    • v.18 no.6
    • /
    • pp.1729-1750
    • /
    • 2018
  • Voltage source inverters (VSIs) are widely used to drive induction motors in industry applications. The quality of output waveforms depends on the switching sequences used in pulse width modulation (PWM). In this work, all existing optimal space vector pulse width modulation (SVPWM) switching strategies are studied. The performance of existing SVPWM switching strategies is optimized to realize a tradeoff between quality of output waveforms and switching losses. This study generalizes the existing optimal switching sequences for total harmonic distortions (THDs) and switching losses for different modulation indexes and reference angles with a parameter called quality factor. This factor provides a common platform in which the THDs and switching losses of different SVPWM techniques can be compared. The optimal spatial distribution of each sequence is derived on the basis of the quality factor to minimize harmonic current distortions and switching losses in a sector; the result is the minimum ripple loss SVPWM (MRSLPWM). By employing the sequences from optimized switching maps, the proposed method can simultaneously reduce THDs and switching losses. Two hybrid SVPWM techniques are proposed to reduce line current distortions and switching losses in motor drives. The proposed hybrid SVPWM strategies are MRSLPWM 30 and MRSLPWM 90. With a low-cost PIC microcontroller (PIC18F452), the proposed hybrid SVPWM techniques and the quality of output waveforms are experimentally validated on a 2 kVA VSI based on a three-phase two-level insulated gate bipolar transistor.