• Environmental Analysis Health and Toxicology
• /
• v.21 no.3 s.54
• /
• pp.291-299
• /
• 2006

The experiments investigated whether early exposure to testosterone propionate (TP) during prepuberty alters testis development in Sprague-Dawley male rats. We performed Hershberger assay using the stimulated weanling male rats by OECD protocols, cDNA microarray, and Western blot. TP was subcutaneously injected to uncastrated Sprague-Dawley male rat of 22 days old for 10 consecutive days at doses of 0.4, 0.8, 1.0, 1.2, 1.6 mg/kg per day. At necropsy, the following tissues were removed and weighed: combined testes, epididymides (Epi), Cowper's glands (COW), levator am, and bulbocavernosus muscles (LABC), seminal vesicles, together with coagulating gland (SV) and ventral prostate (VP). We found that TP increased the weights of Epi, VP, SV, COW, and LABC, while testis was decreased in a dose-dependent manner. In cDNA microarray analysis of testis, there were significant reductions in the expression of cytochrome P450 11A (CYP11A), the rate-limiting enzyme of steroidogenesis. Taken together these results, TP exposure before puberty in male rats may produce the delay in testis development by inhibiting the CYP11A gene expression.

• Journal of Information Processing Systems
• /
• v.15 no.6
• /
• pp.1472-1488
• /
• 2019

Critical elements in the China's Lunar Exploration reside in that the lunar rover travels over the surrounding undetermined environment and it conducts scientific exploration under the ground control via teleoperation system. Such an interplanetary transportation mission teleoperation system belongs to the ground application system in deep space mission, which performs terrain reconstruction, visual positioning, path planning, and rover motion control by receiving telemetry data. It plays a vital role in the whole lunar exploration operation and its so-called trustworthy evidence must be assessed before and during its implementation. Taking ISO standards and China's national military standards as trustworthy evidence source, the net assessment model and net assessment method of teleoperation system are established in this paper. The multi-dimensional net assessment model covering the life cycle of software is defined by extracting the trustworthy evidences from trustworthy evidence source. The qualitative decisions are converted to quantitative weights through the net assessment method (NAM) combined with fuzzy analytic hierarchy process (FAHP) and entropy weight method (EWM) to determine the weight of the evidence elements in the net assessment model. The paper employs the teleoperation system for interplanetary transportation as a case study. The experimental result drawn shows the validity and rationality of net assessment model and method. In the final part of this paper, the untrustworthy elements of the teleoperation system are discovered and an improvement scheme is established upon the "net result". The work completed in this paper has been applied in the development of the teleoperation system of China's Chang'e-3 (CE-3) "Jade Rabbit-1" and Chang'e-4 (CE-4) "Jade Rabbit-2" rover successfully. Besides, it will be implemented in China's Chang'e-5 (CE-5) mission in 2019. What's more, it will be promoted in the Mars exploration mission in 2020. Therefore it is valuable to the development process improvement of aerospace information system.

• Journal of Digital Contents Society
• /
• v.11 no.4
• /
• pp.417-424
• /
• 2010

In this paper the real-time face region was detected by suggesting the rectangular feature-based classifier and the robust detection algorithm that satisfied the efficiency of computation and detection performance was suggested. By using the detected face region as a recognition input image, in this paper the face recognition method combined with PCA and the multi-layer network which is one of the intelligent classification was suggested and its performance was evaluated. As a pre-processing algorithm of input face image, this method computes the eigenface through PCA and expresses the training images with it as a fundamental vector. Each image takes the set of weights for the fundamental vector as a feature vector and it reduces the dimension of image at the same time, and then the face recognition is performed by inputting the multi-layer neural network.

• Geotechnical Engineering
• /
• v.8 no.3
• /
• pp.23-36
• /
• 1992

The flat dilatometer(DMT) has been practically used as an in-situ test equipment. It is a simple, rapid and cost-effective tool to characterize the in-situ stress-strain-strength properties of various types of ground materials. However, the results of flat DMT should be validated with considerable data with respect to the known reference values for a specific site. In this study, the applicability of existing relationships which were established for other local deposits is verified by performing the tests in several clay deposits. To compare with the DMT results, field vane tests and cone penetration tests were also carried out in the same field as reference tests, and unconsolidated undrained tests, oedometer tests, and other fundamental material properties tests were conducted on the thin-walled tube samples in the laboratory. The results of the flat DMT combined with empirical correlations are used to estimate soil types, unit weights, coefficients of lateral earth pressure at rest, overconsolidation ratios, constrained moduli and undrained shear strengths of three clay local deposits. It was found that various geotechnical properties estimated from the flat DMT generally well agree with those from the reference tests.

• Journal of the Institute of Convergence Signal Processing
• /
• v.12 no.2
• /
• pp.113-118
• /
• 2011

In this paper, we develop a speaker gender classification technique using collaborative sensor fusion for use in a wireless sensor network. The distributed sensor nodes remove the unwanted input data using the BER(Band Energy Ration) based voice activity detection, process only the relevant data, and transmit the hard labeled decisions to the fusion center where a global decision fusion is carried out. This takes advantages of power consumption and network resource management. The Bayesian sensor fusion and the global weighting decision fusion methods are proposed to achieve the gender classification. As the number of the sensor nodes varies, the Bayesian sensor fusion yields the best classification accuracy using the optimal operating points of the ROC(Receiver Operating Characteristic) curves_ For the weights used in the global decision fusion, the BER and MCL(Mutual Confidence Level) are employed to effectively combined at the fusion center. The simulation results show that as the number of the sensor nodes increases, the classification accuracy was even more improved in the low SNR(Signal to Noise Ration) condition.

• Journal of The Korean Society of Grassland and Forage Science
• /
• v.41 no.3
• /
• pp.162-167
• /
• 2021

Aluminum (Al) stress in acidic pH is known to decrease the growth and productivity of alfalfa. However, not much is known about how the application of silicon (Si) affects the Al stress response in alfalfa. This study was conducted to evaluate the effect of exogenous application of Si on the growth of alfalfa seedlings exposed to Al stress in pots. Alfalfa seedlings grown in pots for 2 weeks were treated either Al stress (pH 4.0, 0.2 mM Al) or Al stress + Si (1 mM) for 5 days, lengths and biomass of shoot and root, and chlorophyll and carotenoid contents in leaf tissues were analyzed respectively. Al stress treatment inhibited shoot and root growth, and decreased fresh and dry weights, and chlorophyll content in leaves, but increased carotenoid content. In contrast, when alfalfa seedlings treated with Al stress combined with Si, delayed growth caused by Al stress of shoot and root of alfalfa seedlings was restored, dry weight was increased and chlorophyll content of leaf tissue was increased, but carotenoid content was decreased. These results suggest that Si has a function of alleviating Al toxicity in alfalfa, of which it exhibits a mitigating effect by a function that overlaps with some of the intracellular functions of carotenoids.

• Research in Community and Public Health Nursing
• /
• v.31 no.spc
• /
• pp.549-562
• /
• 2020

Purpose: This study aimed to identify individual- and regional-level factors associated with perceived good health and multimorbidity among older adults. Methods: Secondary analysis of the 2017 Korea Community Health Survey was conducted on a sample of 67,532 older adults. The individual level data set was combined with regional-level factors from the administrative data released on the Korea National Statistical Office website. Distribution of perceived good health and multimorbidity in 254 public health centers were calculated using sampling weights and presented as percentages. Multilevel logistic regression analyses were used to identify individual- and regional-level factors associated with perceived good health and multimorbidity. Results: Overall, 21.1% of subjects perceived their health to be good, ranging from 9.3% to 39.4% by region. The prevalence of multimorbidity was 15.9%, and varied between 6.6% and 22.6% by region. At the individual level, perceived good health was associated with men, younger age, higher educational levels, higher income levels, and those married and living with a partner and maintaining a healthy lifestyle. At the regional level, higher rates of health center personnel among public officials and higher levels of financial independence were associated with perceived good health. Multimorbidity was associated with marital status and healthy lifestyle, and higher rates of health center personnel among public officials. Conclusion: Regional factors such as health care personnel and local economy could affect population health. Our findings suggest the need to consider individual- and regional-level factors to promote good health among older adults and reduce the health gap by region.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
• /
• v.27 no.3
• /
• pp.37-46
• /
• 2021

Background: The increase in the activity of the upper trapezius (UT) muscle and decrease in the activity of the serratus anterior (SA) and lower trapezius (LT) muscle produce an abnormal scapulohumeral rhythem. Therefore, the SA is the focus of therapeutic exercise protocols for the rehabilitation. This study aimed to compare the activity of the muscles according to resistance levels during protraction exercise. Methods: Thirteen healthy 20 to 30 years old male and female subjected participated in the study. All subjects performed the scapular protraction exercise with the weights of 0, 5, and 10kg, combined with horizontal shoulder abduction and adduction. The electromyography data of the SA, UT, and pectoralis major (PM) during the exercise were recorded using surface electrodes. The ratios of PM/SA and UT/SA were calculated. Repeated one-way ANOVA was used to determine the statistical significance. Results: There was a significant difference in the muscle activity of the SA and PM (p<.05). Specifically, SA had the highest activity and PM had the lowest activity at an abduction resistance 10kg (p<.01). There was a significant difference in the ratios of UT/SA and PM/SA (p<.05). The ratio of PM/SA was the lowest at the abduction resistance of 10kg (p<.01). Conclusion: According to this study, for the selective activation of the serratus anterior, protraction exercises should be applied as a method of adding resistance to protraction and horizontal abduction.

• Journal of Soil and Groundwater Environment
• /
• v.27 no.spc
• /
• pp.92-98
• /
• 2022

Although various methods have been proposed to assess groundwater vulnerability, most of the models merely consider the mobility of contaminants (i.e., intrinsic vulnerability), and the attenuation capacity of vadose zone is often neglected. This study proposed an evaluation model for the attenuation capacity of vadose zone to supplement the limitations of the existing index method models for assessing groundwater vulnerability. The evaluation equation for quantifying the attenuation capacity was developed from the combined linear regression and weighted scaling methods based on the lab-scale experiments using various vadose zone soils having different physical and biogeochemical properties. The proposed semi-quantifying model is expected to effectively assess the attenuation capacity of vadose zone by identifying the main influencing factors as input parameters together with proper weights derived from the coefficients of the regression results. The subsequent scoring and grading system has great versatility while securing the objectivity by effectively incorporating the experimental results.

• Journal of Microbiology and Biotechnology
• /
• v.31 no.6
• /
• pp.855-866
• /
• 2021

The effects of various carbon sources on mycelial growth and polysaccharide synthesis of the medicinal fungus Inonotus obliquus in liquid fermentation were investigated. After 12-d fermentation, mycelial biomass, polysaccharide yield, and polysaccharide content were significantly higher in Glc+Lac group (glucose and lactose used as combined carbon source) than in other groups. Crude polysaccharides (CIOPs) and the derivative neutral polysaccharides (NIOPs) were obtained from mycelia fermented using Glc, fructose (Fru), Lac, or Glc+Lac as carbon source. Molecular weights of four NIOPs (termed as NIOPG, NIOPF, NIOPL, and NIOPGL) were respectively 780.90, 1105.00, 25.32, and 10.28 kDa. Monosaccharide composition analyses revealed that NIOPs were composed of Glc, Man, and Gal at different molar ratios. The NIOPs were classified as α-type heteropolysaccharides with 1→2, 1→3, 1→4, 1→6 linkages in differing proportions. In in vitro cell proliferation assays, viability of RAW264.7 macrophages was more strongly enhanced by NIOPL or NIOPGL than by NIOPG or NIOPF, and proliferation of HeLa or S180 tumor cells was more strongly inhibited by NIOPG or NIOPGL than by NIOPF or NIOPL, indicating that immune-enhancing and anti-tumor activities of NIOPs were substantially affected by carbon source. qRT-PCR analysis revealed that expression levels of phosphoglucose isomerase (PGI) and UDP-Glc 4-epimerase (UGE), two key genes involved in polysaccharide synthesis, varied depending on carbon source. Our findings, taken together, clearly demonstrate that carbon source plays an essential role in determining structure and activities of I. obliquus polysaccharides by regulating expression of key genes in polysaccharide biosynthetic pathway.