• Journal of Biomedical Engineering Research
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• v.33 no.4
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• pp.194-201
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• 2012

This study was designed to investigate the effect of a combined stimulus which was composed of chiropractic massage and thermotherapy on the relief of mental and physical stress. Fifteen healthy male subjects were treated with three type of stimuli; control (without any stimulus), a single stimulus (only chiropractic) and a combined stimulus. To evaluate the effects of stimuli, visual analogue scale (VAS), trunk extension, electromyogram (EMG) on erector spinae muscle and electrocardiogram (ECG) were measured and analyzed before and after stimuli. In the control group, there were no significant changes in EMG root mean square (RMS) value and low Frequency/high Frequency (LF/HF) ratio (p > 0.05, p > 0.05). However, both stimulus groups showed significant increases in trunk extension and EMG RMS values (p < 0.05, p < 0.05), but significant decreases in LF/HF ratios (p < 0.05). Particularly the decrement rate in LF/HF ratio was significantly higher in the combined stimulus group than that in the single stimulus group (p < 0.05). Also, a significantly lower VAS was recorded after combined stimulus. Our findings indicate that the combined stimulus might not only improve flexibility and strength of muscle, but also active parasympathetic nerve activity. The combined stimulus may thus contribute to relieve the stress and to enhance the muscle function.

• Science of Emotion and Sensibility
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• v.4 no.1
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• pp.43-51
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• 2001

When consumer evaluates a product, every aspec of the product affects the evaluation. Human uses at least five sensory organs for the evaluation. Multi-sensory or multi-modal design tries to add auditory and olfactory factors to the traditional visual-centered design. For the multi-modal design, it is essential to understand relationships between combined sensory stimuli and human sensibility. Information between simple sensory stimulus and human sensibility is pre-requisite to combine multi-modal stimuli. This study investigated human sensibility against 8 colors and 30 sounds, presented independently. The combined stimuli of color and sound were made based on the sensibility generated by each stimulus. Human sensibility generated by the combined stimuli of color and sound were made based on the sensibility generated by each stimulus. Human sensibility generated by the combined stimuli was investigated with 20 female subjects. For combined stimuli that generated the same kind of sensibility respectively, generated sensibility was same but strength was diminished. For combined stimuli that generated the different sensibilities respectively, subjects showed neutral sensibility or no special sensibilities. Sensibilities to the same stimuli also showed difference depending on personal background of the subjects.

• Journal of International Academy of Physical Therapy Research
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• v.1 no.2
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• pp.143-148
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• 2010

The present study examined the effects of functional electrical stimulus(group 1), proprioceptive neuromuscular facilitation(group 2) and combined training of functional electrical stimulus and proprioceptive neuromuscular facilitation(group 3) with scapula adductor muscles on scapula movement, upper limb function and gait in fifteen subjects stroke patients. The training was thirty minutes a day, five times a week for six weeks, obtained result as follow, upper limb function was significant difference in the group 2(p<.05) but no significant difference in other groups. The change of weight bearing were significant difference in all the groups(p<.05), and increase of gait velocity were significant difference in all the group(p<.05). In conclusion, when applied with functional electrical stimulus, proprioceptive neuromuscular facilitation and combined training to the scapular adductor muscles, it was oberved in the course of the experiment that proprioceptive neuromuscular facilitation was the most effective treatment among the three methods applied to the scapula adductors.

• Journal of the Korean Society of Visualization
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• v.13 no.2
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• pp.22-27
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• 2015

Caenorhabditis elegans (C.elegans) has various interesting behavioral properties, such as chemotaxis, thermotaxis, and electrotaxis. However, most previous research were only focused on single-stimulus for studying its behavioral properties. In this paper, we propose a simple and effective device for analyzing the behavior of C.elegans with combined stimuli, electric field and temperature. We compared and analyzed wild type worms (N2) and four mutant worms (tax-4, ttx-7, unc-54, unc-6). We analyzed the reaction of worms to certain stimulus and identified that this device is effective to apply a combined stimulus.

• Journal of Biomedical Engineering Research
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• v.22 no.4
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• pp.331-338
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• 2001

In this paper, we have proposed a new computer retina model reflecting the mechanism of transient amacrine cell on the basis of a conventional computer retina model to understand mechanism of visual information processing. The conventional computer retina model contained most of mechanism for other retina models and it was verified with the physiological data. However, we found that a conventional computer retina model doesn't have the mechanism of amacrine cell that was likely to respond to moving stimulus. In proposed model, therefore, a conventional computer model that considered from photoreceptors to bipolar cells and a new computer model that considered for transient amacrine cell and ganglion cell was combined. As we compared the physiological data with the results of computer simulation of transient amacrine cell about fixed stimulus and moving stimulus, we confirmed that the proposed new computer retina model was normally operated.

• Journal of Audiology & Otology
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• v.24 no.3
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• pp.149-156
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• 2020

Background and Objectives: The gap prepulse inhibition of the acoustic startle response has been used to screen tinnitus in an animal model. Here, we examined changes in the auditory late response under various conditions of gap prepulse inhibition. Subjects and Methods: We recruited 19 healthy adults (5 males, 14 females) and their auditory late responses were recorded after various stimuli with or without gap prepulsing. The N1 and P2 responses were selected for analysis. The gap prepulse inhibition was estimated to determine the optimal auditory late response in the gap prepulse paradigm. Results: We found that the gap per se generated a response that was very similar to the response elicited by sound stimuli. This critically affected the gap associated with the maximal inhibition of the stimulus response. Among the various gap-stimulus intervals (GSIs) between the gap and principal stimulus, the GSI of 150 ms maximally inhibited the response. However, after zero padding was used to minimize artifacts after a P2 response to a gap stimulus, the differences among the GSIs disappeared. Conclusions: Overall, the data suggest that both the prepulse inhibition and the gap per se should be considered when using the gap prepulse paradigm to assess tinnitus in humans.

• Korean Journal of Audiology
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• v.24 no.3
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• pp.149-156
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• 2020

Background and Objectives: The gap prepulse inhibition of the acoustic startle response has been used to screen tinnitus in an animal model. Here, we examined changes in the auditory late response under various conditions of gap prepulse inhibition. Subjects and Methods: We recruited 19 healthy adults (5 males, 14 females) and their auditory late responses were recorded after various stimuli with or without gap prepulsing. The N1 and P2 responses were selected for analysis. The gap prepulse inhibition was estimated to determine the optimal auditory late response in the gap prepulse paradigm. Results: We found that the gap per se generated a response that was very similar to the response elicited by sound stimuli. This critically affected the gap associated with the maximal inhibition of the stimulus response. Among the various gap-stimulus intervals (GSIs) between the gap and principal stimulus, the GSI of 150 ms maximally inhibited the response. However, after zero padding was used to minimize artifacts after a P2 response to a gap stimulus, the differences among the GSIs disappeared. Conclusions: Overall, the data suggest that both the prepulse inhibition and the gap per se should be considered when using the gap prepulse paradigm to assess tinnitus in humans.

• Journal of the Korean Society of Clothing and Textiles
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• v.23 no.1
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• pp.78-89
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• 1999

Clothes enhance visual images through the interaction between space and background of the wearer. The influence of background is important as that of the clothes when the observer understands the images. We look at fashion pictures used as important as that various backgrounds are presented depending on the image of the clothes. The clothing the model wears in the pictures takes on shape and space which supports the clothes. The background interact to from the whole image. The background has an important influence on the delivery of image for the clothes. However when the clothes are presented in the background there are some cases that all or parts of clothes can be shown. We must consider the composition ratio of the clothes and background which influences the whole image of the clothing. These interactions and influences on the whole image in regards to clothing background and the ratio will be the focus of this study. clothing was Modern Mannish Casual, Feminine, Ground was decided artificial setting 1 natural setting 1, indoor setting 1, artificial setting 2, natural setting 2, indoor setting 2, Percentage of Clothing was 80% , 140%, 200%,. Thus visual stimulus were 72 pictures that were combined Clothing Ground and Percentage of Clothing, the main survey of questionary consisted of their evaluation of the Picture image combined Clothing and Ground by 30 semantic differential bi-polar scales and the subjects were 50 students majoring in clothing and textile. The data analyzed by factor analysis MCA, MDS, The major finding were as follows : 1) As a result of factor analysis, 5 factors -Attractiveness Hardness and softness Cuteness Attention Cool and Warm factor were found out as constructing factors the Picture image combined Clothing and Ground 2) According to multidimensional positioning map were presented in a stimulus position the perceptive image differed in degree of similarity as a ground construction of stimulus in spite of same clothing image. It will aid in choosing the most beneficial background for any clothing brand. It will enhance the picture images to their full potential in any advertising medium.

• Journal of Acupuncture Research
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• v.21 no.6
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• pp.167-176
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• 2004

Objective : This study was designed to investigate the effects of electro-acupuncture(EA) and moxibustion at CV13, CV12, CV10 and ST36 serum gastin level in rats. Methods : The present study was conducted to see the effects produced by combined electro-acupuncture(EA) and moxibustion using four different acupoints on serum gastrin level in rats. Electro-acupuncture (2 Hz, intensity ; 10 times muscle twitch threshold) was applied for 30 minutes to ST36 under halothane anesthesia. Moxibustion ($1.6{\pm}0.3mg$, 5 times of a day) was applied during 3 days to CV13, CV12, CV10 under halothane anesthesia. Results : Both of EA applied to the ST 36 and Moxibustion applied to the CV10, CV12 decreased serum gastrin level significantly. And the effect of combined EA at ST36 and moxibustion at CV10 was shown stronger effect than each singular stimulus of EA at ST36 and moxibustion at CV10. These data suggest that both of EA and moxibustion at specific acupoints produce change of serum gastrin level in rats and combined EA and moxibustion was shown quite effect than each singular stimulus.

• The Journal of Korean Medicine
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• v.21 no.3
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• pp.3-8
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• 2000

1. Definition : Bee-venom therapy does not involve actual bee-stings: it is a treatment method with acquired bee-venom extract through the electric stimulus on the bee, It is injected subcutaneusly on the acupuncture point after refining, according to the diagnosis of constitution and disease. 2. History : Around 2000 B.C., records that Bee-venom was used for therapy were written in the medical book of Babylonia and Papirus of ancient Egypt. Hippocrates, who is called the father of Medicine, said that Bee-venom is Arcanum, which means mysteric medicine. In Oriental medicine, B.C. 200, there was a clinical record that the meat suspended in front of the bee house on the tree in order to get bee-venom, was attached on the lesion. 3. Mechanism of Action : There are two aspects: 1) The effect of stimulating acupunture point It is similar to the chemical moxa. I think that there are several methods of stimulating the acupuncture point： For example, a simple needle is a mechanical stimulus, Moxa is a heating stimulus and electric and Raser acupunture etc. And another stimulus: in the ancient orient, a chemical stimulus called Chungu(Tianjiu), is attached to the lesions by using grinded insects (ex. Mylaris phalerate PALL.) which have toxin. So Bee venom therapy is similar to this. 2) The effect of biochemical ingredients Bee venom consists of 40 kinds of ingredients. For example, me Iii tin, Apamin, Pospholipase A2, MCD peptide, Adolapin and so on. They have effects which have been proven through experimentation l) tonifying mechanism of the body through increasing hormon secretion 2) tonifying immune system through proliferation of WBC, lymphocytes, macrophage 3) anti-inflammatory reaction Therefore Bee venom therapy is the representative 3rd Medicine, which combined East & West medicine. 4. Application of disease : L.B.P and HIVD, O.A, R.A, degenerative arthritis, shoulder pain and other pain diseases. 5. Therapic methods : According to constitution and disease, proper concentration of bee venom is injected on acupunture point, 2 times a week. Generally one term is consisted of 15times. 6. Contraindication : Heart disease, TBc, DM, kidney disease(nephritis), pregnancy, woman in menstruation 3-4 persons per 100,000 persons may have severe allergic reaction.