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The Effects of Red Ginseng Product and Combined Exercise on Blood Lipids and Body Composition of Obese Women in Their Twenties (복합운동과 홍삼복합제의 투여가 20대 비만여성의 혈중 지질 및 체구성에 미치는 영향)

  • Kim, Sung-Soo;Kim, Jae-Deung;Kim, Hong;Shin, Mal-Soon;Park, Chae-Kyu;Park, Myung-Han;Yang, Jai-Won
    • Journal of Ginseng Research
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    • v.26 no.2
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    • pp.59-66
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    • 2002
  • This study was carried out to investigate the effects of red ginseng product and combined exercise on the changes of blood lipids(total cholesterol, high density lipoprotein, low density lipoprotein, triglyceride) and body composition (weight, % body fat) of obese women in their twenties. The experiments were performed with 21 women who had up to 30% body fat. They were randomly assigned into three groups [CON : control group (n=7), EXPI : red ginseng product group (n=7), EXP2 red ginseng product + exercise group (n=7)]. EXPI group and EXP2 group took red ginseng product for 12 weeks, and especially EXP2 group performed combined three-times-a-week exercise during the experiments period, too. The blood of each group was also sampled for three times (before experiments, after 8 weeks, after 12 weeks) to know the changes of blood lipid profile. Weight and %body fat were measured by body composition analyser. After 12 weeks, weight increased in CON group, but decreased in EXP1 and EXP2 group significantly. %body fat significantly decreased in EXP1 and EXP2 group, but not in CON group. When other two groups steadily increased in TC, EXP2 group constantly decreased, although there was no significant difference. After 12 weeks, while CON group and EXP2 group decreased within narrow limits in HDL-C, EXPI group was showing a rising tendency. But couldn't find any significant difference. Between the 8th and the 12th week, CON group and EXPI group were showing a rising tendency in LDL-C. But there was little change in EXP2 group. The results of ANOVA didn't show any significant difference. In TG, CON group and EXP2 group had little change. On the other hand, EXPI group steadily decreased. But there was no significant difference. In conclusion, with the 12-week experiments, weight and %body tat significantly decreased by red ginseng product and combined exercise which could derive profitable changes from blood lipids-especially total cholesterol, HDL-C, TG.

Significance of Ground Water Movements in the Numerical Modelling of Tunnelling (터널해석에 있어 지하수 거동의 중요성)

  • 신종호
    • Proceedings of the Korean Geotechical Society Conference
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    • 2003.03a
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    • pp.257-264
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    • 2003
  • Tunnelling in water bearing soils influences the ground water regime. It has been indicated in the literature that the existence of ground water above a tunnel influences tunnel stability and the settlement profile. Only limited research, however, has been done on ground water movements around tunnels and their influence on tunnel performance. Time dependent soil behaviour can be caused by the changes of pore water pressure and/or the viscous properties of soil(creep) under the stress change resulting from the advance of the tunnel face. De Moor(1989) demonstrated that the time dependent deformations due to tunnelling are mainly the results of pore pressure dissipation and should be interpreted in terms of effective stress changes. Drainage into tunnels is governed by the permeability of the soil, the length of the drainage path and the hydraulic boundary conditions. The potential effect of lime dependent settlement in a shallow tunnel is likely to occur rapidly due to the short drainage path and possibly high coefficient of consolidation. Existing 2D modelling methods are not applicable to these tunnelling problems, as it is difficult to define empirical parameters. In this paper the time-based 2D modelling method is adopted to account for the three dimensional effect and time dependent behaviour during tunnel construction. The effect of coupling between the unloading procedure and consolidation during excavation is profoundly investigated with the method. It is pointed out that realistic modelling can be achieved by defining a proper permeability at the excavation boundary and prescribing appropriate time for excavation Some guidelines for the numerical modelling of drained and undrained excavation has been suggested using characteristic time factor. It is highlighted that certain range of the factor shows combined effect between the unloading procedure due to excavation and consolidation during construction.

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A Study on Optimization of Tooth Micro-geometry for Wind Turbine High Speed Stage Helical Gear Pair (풍력터빈용 고속단 헬리컬 기어의 치형 최적화에 관한 연구)

  • Cho, Sungmin;Lee, Do-Young;Kim, Laesung;Cho, Sangpil;Lyu, Sung-Ki
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.13 no.5
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    • pp.15-20
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    • 2014
  • The wind industry grew in the first decade of the 21st century at rates consistently above 20% a year. For wind turbine, gearbox failure can be extremely costly in terms of repair costs, replacement parts, and in lost power production due to downtime. In this paper, gear tooth micro-modification for the high speed stage was used to compensate for the deformation of the teeth due to load and to ensure a proper meshing to achieve an optimized tooth contact pattern. The gearbox was firstly modeled in a software, and then the various combined tooth modification were presented, and the prediction of transmission under the loaded torque for the helical gear pair was investigated, the normal load distribution and root stress were also obtained and compared before and after tooth modification under one torque. The simulation results showed that the transmission error and normal load distribution under the load can be minimized by the appropriate tooth modification. It is a good approach where the simulated result is used to improve the design before the prototype is available for the test.

Development of Hybrid Career Coaching Model and Effect Analysis (하이브리드 진로코칭 모형 개발 및 효과분석)

  • Go, Eun-Hyeon;Park, Hye-Rim;Kim, Do-Hyeon
    • The Journal of Korean Association of Computer Education
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    • v.18 no.6
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    • pp.43-51
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    • 2015
  • In this paper, we develops the hybrid career coaching model combined the face to face and the E-coaching, and applies students of childhood education for career guidance. The presented hybrid career coaching manages a profile and state information and a remote access between the coach and coachee on Internet. Then, online part of hybrid coaching deals with saving the data, and understand of the situation of the coachee if it is necessary. And face to face part of hybrid coaching have a conversation, the checking, counsel and introspection if the coach needs. Presented hybrid career coaching model has th procedure of 6 steps such like career coaching guidance, self-understanding, career decision-making, establishment of the career execution planning, execution plan and action will inspection and execution result inspection. Proposed hybrid career coaching is possible to understand coachee's current state on the career map, realize the importance of the execution strategy and maximize the efficiency and effectiveness self-regulation capacity.

Method Development for the Odor-Active Compound Determination by Gas Chromatography/Flame Ionization Detection/Olfactometry (냄새성분 측정을 위한 기체 크로마토그래피/불꽃이온화 검출/후각 검출법의 개발)

  • Kim, Man-Goo;Jung, Young-Rim;Seo, Young-Min;Yang, Hee-Hwa
    • Analytical Science and Technology
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    • v.14 no.2
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    • pp.180-190
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    • 2001
  • Oder-active compounds are complex in a sample. These compounds are usually analyzed by GC or GC/MSD while such analytical measurement can quantify specific volatile organic compounds, it has limitations in identifying odor-active compounds. To resolve this problem, GC-Sniffing or GC-Olfactometry method has been attempted. In this study, GC/FID/Olfactometry system was developed. This system can simultaneously sniff and detect GC effluents by traditional GC combined with human olfactory system. The time gap between FID and ODP response was dependent on the kinds and concentrations of chemicals and panels, with more volatile, stronger and shorten breath cycle panel showing narrow time gap. Thus, clear relationship between FID and ODP should be considered to identify the odor-active compounds.

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Aeroelastic-aerodynamic analysis and bio-inspired flow sensor design for boundary layer velocity profiles of wind turbine blades with active external flaps

  • Sun, Xiao;Tao, Junliang;Li, Jiale;Dai, Qingli;Yu, Xiong
    • Smart Structures and Systems
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    • v.20 no.3
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    • pp.311-328
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    • 2017
  • The characteristics of boundary layers have significant effects on the aerodynamic forces and vibration of the wind turbine blade. The incorporation of active trailing edge flaps (ATEF) into wind turbine blades has been proven as an effective control approach for alleviation of load and vibration. This paper is aimed at investigating the effects of external trailing edge flaps on the flow pattern and velocity distribution within a boundary layer of a NREL 5MW reference wind turbine, as well as designing a new type of velocity sensors for future validation measurements. An aeroelastic-aerodynamic simulation with FAST-AeroDyn code was conducted on the entire wind turbine structure and the modifications were made on turbine blade sections with ATEF. The results of aeroelastic-aerodynamic simulations were combined with the results of two-dimensional computational fluid dynamic simulations. From these, the velocity profile of the boundary layer as well as the thickness variation with time under the influence of a simplified load case was calculated for four different blade-flap combinations (without flap, with $-5^{\circ}$, $0^{\circ}$, and $+5^{\circ}$ flap). In conjunction with the computational modeling of the characteristics of boundary layers, a bio-inspired hair flow sensor was designed for sensing the boundary flow field surrounding the turbine blades, which ultimately aims to provide real time data to design the control scheme of the flap structure. The sensor element design and performance were analyzed using both theoretical model and finite element method. A prototype sensor element with desired bio-mimicry responses was fabricated and validated, which will be further refined for integration with the turbine blade structures.

General Pharmacology of DWP 302, a New Combined Drug for Gastroduodenal Diseases (위장질환 치료용 의약조성물(BWP 302)의 일반약리작용)

  • 임승욱;염제호;김영만;장병수;남권호;김동오;유영효;박명환
    • Biomolecules & Therapeutics
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    • v.1 no.2
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    • pp.211-219
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    • 1993
  • The general and some pharmacological actions of DWP 302 were investigated in animals and the following results were obtained. In central nervous system, DWP 302 had no effects on the pentobarbital induced anaesthesia, locomotor activity, rotarod test, traction test, analgesic action in the mice and body temperature in the rat. DWP 302 showed no depressive action on the convulsion induced by strychnine and electronic shock. From these results, DWP 302 was considered to have no or little pharmacological effect on the central nervous system. Furthermore, DWP 302 had no influences on the normal blood pressure and heart rate. In the isolated ileum of guinea pig, DWP 302 showed neither contractive nor relaxing effects against the acetylcholine ($10^{-6}g/mι$), histamine ($10^{-6}g/mι$) and $BaCl_2$ ($10^{-4}g/mι$) at a concentration of $1.9{\times}10^{-4}g/mι$ in bath. But it caused a slight increase in basal tone at a concentration of $6.3{\times}10^{-4}g/mι$ and this effect was inhibited by atropine $10^{-7}g/mι.$ In the isolated trachea and vas deference, DWP 302 showed no effect on the contractions produced by histamine and norepinephrine, respectively. And DWP 302 showed no effect on the contractions produced by acetylcholine and oxytocin in the isolated nonpregnant rat uterus. DWP 302 had no effect on bile excretion, urine volume, pH and gastrointestinal motility, But, DWP 302 showed a significant inhibitory effect on gastric secretion in the rat.

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Predicting Quality of Life in People with Cancer (추후관리 암환자의 삶의 질 영향요인 분석)

  • 오복자
    • Journal of Korean Academy of Nursing
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    • v.27 no.4
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    • pp.901-911
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    • 1997
  • The purpose of this study is to provide a basis for nursing intervention strategies to promote quality of life in cancer patients. Therefore the study is designed to evaluate the effectiveness of perceived health status, self-esteem, health locus of control, self-efficacy, perceived susceptibility /severity, health promoting behaviors, and hope for quality of life. The sample was composed of 164 stomach cancer patients who visited outpatient clinics at a university hospital in Seoul. The following instruments were used in the study after some adaptation : Lawstone and others' Health Self-rating Scale, Rosenberg's Self-esteem Scale, Wallston and others 'Multidimensional Health Locus of Control Scale, Sherer & Maddux's Self-efficacy Scale, Moon's Health Beliefs Scale, Walker and others' Health Promoting Lifestyle Profile, Nowotney's Hope scale and Noh's Quality of Life Scale. Data were analyzed using a SAS program for Pearson correlation coefficients, descriptive correlational statistics and stepwise multiple regression. The results are as follows : 1. The scores on the quality of life scale ranged from 115 to 243 with a mean of 177.84(SD : 25.35). The mean scores(range 1-5) on the different dimensions were : emotional state 3.37 : economic life 3.47 : physical state & function 3.52 : self-esteem 3.66 : relationship with neighbors 3.37 ; family relationships 3.80. 2. There was a significant correlation between all the predictive variables and the quality of life (r=.20-.65, p<.01). 3. Stepwise multiple regression analysis showed that : 1) Self-esteem was the main predictor of quality of life and accounted for 46.9% of the variance in quality of life. 2) Perceived health status, hope and perceived susceptibility/severity accounted for 11.8%, 8.3%, 1.5% of the variance in quality of life, respectively. 3) Self-esteem, perceived health status, hope & perceived susceptibility /severity combined accounted for 68.5% of the variance in quality of life. In conclusion, self-esteem, perceived health status, hope and perceived susceptibility / severity were identified as important variables in the quality of life of cancer patients.

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Study of Dynamic Characteristics of 2.5-MW Wind Turbine Gearbox (2.5MW 풍력발전기 기어박스 동특성 연구)

  • Kimg, Jung-Su;Park, No-Gill;Han, Ki-Bong;Lee, Hyoung-Woo
    • Journal of Ocean Engineering and Technology
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    • v.28 no.4
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    • pp.314-323
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    • 2014
  • In this study, a gearbox and blade were modeled in the MASTA program, and the housing and carrier components were modeled using a finite element method. Using substructure synthesis, all the components were combined and used to establish a vibration model of a 2.5-MW wind turbine gearbox. In addition, the safety displacement factor was evaluated using an AGMA data sheet about bearing's outer race for the input shaft and output shaft. As a result, the bearing's outer race for the input shaft, and the radial and axial responses were satisfied by the $1^{st}$ and $2^{nd}$ planetary gears and the $3^{nd}$ helical gear transmission error(TE), respectively. However, the output shaft support bearing's outer race responses were not satisfied with the radial response by the $2^{nd}$ TE and axial response by the $3^{rd}$ TE. To reduce the vibration, tooth modification was needed. After profile tooth modification, at the outer race of the output shaft support bearing, the radial response was reduced by approximately $20{\mu}m$, and the axial response was reduced by approximately $6{\mu}m$.

Proteomic Characterization of the 'Agakong', a Small-seeded Recombinant Inbred Line Derived from 'Eunhakong' (Glycine max) $\times$ 'KLG10084' (Glycine soja)

  • Choi, Ung-Kyu;Ryu, Hyun-Su;Kim, Hyun-Tae;Yun, Sun-Mi;Lee, Su-Jin;Choi, Jae-Dek;Hwang, Young-Hyun;Choi, Soo-Young;Kwon, Oh-Shin
    • Food Science and Biotechnology
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    • v.17 no.5
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    • pp.912-918
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    • 2008
  • This study was conducted to identify the differences in proteomic characteristics of 'Agakong', recombinant inbred line, and its parental genotypes 'Eunhakong' (Glycine max) and 'KLG10084' (G. soja). The isoflavone content of 'Agakong' was 3 times higher than that of its parental lines. A combined high-throughput proteomic approach was employed to determine the expression profile and identity of proteins using 2-dimensional gel electrophoresis and matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry. The overall distribution patterns of proteins are quite similar, but lots of protein spot intensities varied among the genotypes. A total of 41 proteins, representing significant difference in the quantities of protein among the lines, were successfully identified. Among them, more than 50% of the proteins identified were subunits of glycinin and $\beta$-conglycinin, 2 major storage proteins. This study showed that the proteomic analysis could help to define specific changes in protein level and composition, which can occur in the generation of new soybean varieties.