• 약학회지
• /
• 제12권1_2호
• /
• pp.16-31
• /
• 1968

Comparative studies were made on some sulfonamides, used individually and combined with parasympatholytic agents as regards (1) the absorption rate through isolated rat small intestine (in vitro), (2) the absorption rate through rat small intestine (in vivo), and (3) the blood concentration of sulfonamides were examined by its oral administration with each combined drug to rabbits, and the following effects were found, parasympatholytic agents inhibit the absorption of sulfonamides from the small intestinal tract. Comparison of the inhibitic efficiency of parasympatholytic agents is as follows: oxazepam, oxyphencyclimine hydrochloride, probantheline bromide, atropine sulfate (The examples are from the weakest to the strongest). Decrement of the absorption rate of sulfonamides is as follows: sulfadiazine, sulfathiazole, sulfamethoxypyridazine, sulfadimethoxine, sulfamerazine, sulfamethazine (The example are from the strongest to the weakest). Additionally, it is assumed that if the combined drugs were absorbed from the small intestine in the original form, those inhibitic effects should be best regarding to their sulfonamide per parasympatholytic agent combined rate "25:1" than to their any other rates.her rates.

• 기본간호학회지
• /
• 제8권2호
• /
• pp.234-243
• /
• 2001

Purpose : To investigate the effects of exercise combined with behavior modification therapy on the degree of obesity. blood lipid level and self-esteem in obese middle aged women. Method : 18 obese middle-aged women volunteers with a BMI over 30% were assigned to exercise combined with behavior modification therapy (n=9) or to a control group(n=9). For the intervention the experiment group used walking outdoors as excercise and behavior modification therapy for 12 weeks. Result Body weight, BMI, TC, TG, LDL-C, and % TC/HDL-C were significantly decreased in experimental group. Changes in HDL-C and self-esteem were significantly increased in the experimental group. Conclusion : This study provides evidence that regular exercise combined with behavior modification is effective in changing the degree of obesity, blood lipid level and self esteem in obese middle-aged women over 12 weeks.

• 생물정신의학
• /
• 제5권2호
• /
• pp.155-161
• /
• 1998

Mood disorder is a medical illness resulting from the disorder of CNS neurotransmission and its principal therapeutic tool is pharmacotherapy. Psychotherapeutic drugs for mood disorder have some clinical limitations which are due to no or partial response, decreased compliance for drug by the side effects, and delayed therapeutic effects. So, general hope of all clinicians that mood diorder will respond to a single psychotherapeutic agent may be the exception rather than the rule. Recently, combined drug treatments have become increasingly popular to overcome the clinical limitations of individual agent in mood disorder. Combined treatments are usually used for augmenting or initiating rapidly the effect of drug, and for treating different target symptoms or drug side effects. When combined treatments being tried, knowledge of the action mechanism, pharmacokinetics, and pharmacodynamics is crucial to cope with the possible adverse reactions of drugs.

• 동의생리병리학회지
• /
• 제28권1호
• /
• pp.122-127
• /
• 2014

Fire needling is an acupuncture procedure involving the swift pricking of diseased part with a red hot needle. The purpose of the present study is to report the therapeutic effect of acupuncture and fire needling combined therapy on the frozen shoulder patients. Each of patient received combined therapy of acupuncture and fire needling. Fire needling was carried out 2 or 3 times a week. Shoulder pain was evaluated by measuring visual analoge scale (VAS), range of movement (ROM), and global assessment and grade. All of the patinets treated with combined therapy exhibited decreasing of VAS and grade, increasing of ROM and global assessment.

• 동력기계공학회지
• /
• 제8권1호
• /
• pp.69-74
• /
• 2004

A structure-control combined optimal design problem is discussed taking a 3-D truss structure as a design object. We use descriptor forms for a controlled object and a generalized plant because the structural parameters appear naturally in these forms. We consider not only minimum weight design problem for structure system, but also suppression problem of the effect of disturbances for control system as the purpose of the design. A numerical example shows the validity of combined optimal design of structure and control systems. We also consider the validity of sensor-actuator collocation for control system design in this paper.

• 전기학회논문지P
• /
• 제51권4호
• /
• pp.169-174
• /
• 2002

The developments of the solar and the wind power energy are neccessary since the future alternative energies that have no pollution and no limitation are restricted. Currently power generation system of existing problems, combined generation system of photovoltaic(400W) and wind power generation system(400W) was suggested. It combines wind power and solar energy to have the supporting effect from each other. However, weather condition, power compensation device that uses elastic energy of spiral spring to combined generation system was also added for the present study. In an experiment, when output of system gets lower than 12V(charging voltage), power was continuously supplied to load through the inverter by charging energy obtained from generating rotary energy of spiral spring operates in small scale generator.

• The Journal of Asian Finance, Economics and Business
• /
• 제9권4호
• /
• pp.83-92
• /
• 2022

Due to the uncertainty in the order of the integrated model, the SARIMA-LSTM model, SARIMA-SVR model, LSTM-SARIMA model, and SVR-SARIMA model are constructed respectively to determine the best-combined model for forecasting the China-Russia trade turnover. Meanwhile, the effect of the order of the combined models on the prediction results is analyzed. Using indicators such as MAPE and RMSE, we compare and evaluate the predictive effects of different models. The results show that the SARIMA-LSTM model combines the SARIMA model's short-term forecasting advantage with the LSTM model's long-term forecasting advantage, which has the highest forecast accuracy of all models and can accurately predict the trend of China-Russia trade turnover in the post-epidemic period. Furthermore, the SARIMA - LSTM model has a higher forecast accuracy than the LSTM-ARIMA model. Nevertheless, the SARIMA-SVR model's forecast accuracy is lower than the SVR-SARIMA model's. As a result, the combined models' order has no bearing on the predicting outcomes for the China-Russia trade turnover time series.

• Advances in nano research
• /
• 제16권6호
• /
• pp.579-591
• /
• 2024

This study explained the effects of radiation, magnetic field, and nanoparticle shape on the peristaltic flow of an Upper-Convected Maxwell nanofluid through a porous medium in an asymmetric channel for a better understanding of cooling and heating mechanisms in the presence of magnetic fields. These phenomena are modeled mathematically as a system of non-linear differential equations, that are solved under long-wavelength approximation and low Reynolds number conditions using the perturbation method. The results for nanofluid and temperature described the behavior of the pumping characteristics during their interaction with (the vertical position, thermal radiation, the shape of the nanoparticle, and the magnetic field) analytically and explained graphically. Also, the combined effects of thermal radiation parameters and some physical parameters on pressure rise, pressure gradient, velocity, and heat distribution are pointed out. Qualitatively, a reverse velocity appears with combined high radiation and Grashof number or combined high radiation and low volume flow rate. At high radiation, the spherical nanoparticle shape has the greatest effect on heat distribution.

• 대한예방한의학회지
• /
• 제13권3호
• /
• pp.19-28
• /
• 2009

Background : Recently, Medical Act was amended to encourage the induction of combined treatment between Oriental Medicine doctors and Western doctors. As yet, the information infra for combined treatment has not been studied. Objectives : This study aimed to design the architecture of information system for combined treatment of the Oriental and the Western Medicine. Methods : First, we defined the information of combined treatment through the analysis of research trends from the inside and outside of the country. Because the data compatibility is very important, the definition of information must be ahead of anything else. Second, we designed the architecture of information system based on the prior definition. Results : We classified the information for combined treatment by subject such as law, clinic, research, manpower, facilities, and education. In this paper information system examined in three aspects. First the infra layer is organized as hardware, netware, and security. Second is data warehouse layer for the storing, filtering, and extraction of data. Third is service layer which is related to data transmission. And Finally all information for combined treatment is provided through the portal system for medical consumer, political planner, and R&D researcher. Conclusion : In this paper, we studied the essential factors of combined treatment information in the view point of information system. But the detailed design and implementation of information system must be followed to effect this results.

• 정형스포츠물리치료학회지
• /
• 제14권2호
• /
• pp.55-64
• /
• 2018

Purpose : The purpose of this study was to investigate the effect of the sprinter and skater combined patterns on muscle contraction onset time and muscle activation of body stabilizing muscles. Method : Our study included young and healthy men in their 20s. The participants used the sprinter and skater combined patterns of the proprioceptive neuromuscular facilitation (PNF) methods to measure muscle activation and muscle contraction onset time of the trunk muscles. To measure muscle contraction onset time and muscle activation, electrodes were attached to the rectus abdominis (RA), external oblique (EO), internal oblique (IO), and erector spinalis (ES) regions. Significant differences were identified using a paired t-test and a one-way analysis of variance (ANOVA) analysis. Result : In the sprinter combined pattern, the muscle with the fastest onset time of contraction was the RES, and that with the slowest was the RRA (p<.001). In the skater combined pattern, the muscle with the fastest onset time of contraction was the LES, and that with the slowest was the LRA (p<.001). In the sprinter combined pattern, the REO and LIO presented medium muscle contraction onset times (p<.001). In the skater combined pattern, the LEO and RIO presented medium muscle contraction onset times (p<.001). Conclusions: Based on these results, these patterns could be used as exercise methods for the elderly with delayed proactive response speeds of the body stabilization methods due to imbalances in body stabilizing muscles or limbs movement.