• Title/Summary/Keyword: Combinations

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A Comparative Study of Transcription Techniques for Nonlinear Optimal Control Problems Using a Pseudo-Spectral Method

  • Kim, Chang-Joo;Sung, Sangkyung
    • International Journal of Aeronautical and Space Sciences
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    • v.16 no.2
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    • pp.264-277
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    • 2015
  • This article investigates various transcription techniques for the Legendre pseudospectral (PS) method to compare the pros and cons of each approach. Eight combinations from four different types of collocation points and two discretization methods for dynamic constraints, which differentiate Legendre PS transcription techniques, are implemented to solve a carefully selected test set of nonlinear optimal control problems (NOCPs). The convergence property and prediction accuracy are compared to provide a useful guideline for selecting the best combination. The tested NOCPs consist of the minimum time, minimum energy, and problems with state and control constraints. Therefore, the results drawn from this comparative study apply to the solution of similar types of NOCPs and can mitigate much debate about the best combinations. Additionally, important findings from this study can be used to improve the numerical efficiency of the Legendre PS methods. Three PS applications to the aerospace engineering problems are demonstrated to prove this point.

Motility Contrast Imaging for Drug Screening Applications

  • Jeong, Kwan
    • Journal of the Optical Society of Korea
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    • v.19 no.4
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    • pp.382-389
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    • 2015
  • Motility contrast imaging is a coherence-domain imaging technique that uses cellular motility as a fully endogenous imaging contrast agent. Motility is measured inside tissue using a digital holographic coherence gate that extracts dynamic speckle from fixed depths. The dynamic speckle arises from the normal organelle motion inside cells, and from the movement of the cellular membranes driven by the cytoskeleton. It measures cellular activity and the effects of temperature and osmolarity. Motion is sensitive to cytoskeletal drugs, such as the antimitotic drugs used for cancer chemotherapy, and the effects of drug combinations also can be monitored. Motility contrast imaging is a potential tissue-based assay platform for highthroughput screening of pharmaceuticals.

Shear Texture Development and Grain Refinement in Asymmetrically Rolled Aluminum Alloy Sheets : Effects of Shear Combinations (비대칭압연한 알루미늄합금판재의 전단집합조직발달과 결정립미세화 : 전단변형 조합의 영향)

  • 이종국;이동녕
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2003.10a
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    • pp.132-135
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    • 2003
  • Asymmetric rolling, in which the ratio of the rotation rates of the upper and lower rolls was 2, has been used to introduce an intense plastic shear strain for the purpose of grain refinement and developing shear deformation textures through the sheet thickness to improve the strength and plastic strain ratio of AA1050 aluminum alloy sheets. The alloy sheets were rolled at room temperature without lubrication. The textures and microstructures of the sheets were investigated by x-ray diffraction and electron back-scattered diffraction (EBSD) analyses with emphasis on effects of combinations of rot ling directions.

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A Method for Selection of Input-Output Factors in DEA (DEA에서 투입.산출 요소 선택 방법)

  • Lim, Sung-Mook
    • IE interfaces
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    • v.22 no.1
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    • pp.44-55
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    • 2009
  • We propose a method for selection of input-output factors in DEA. It is designed to select better combinations of input-output factors that are well suited for evaluating substantial performance of DMUs. Several selected DEA models with different input-output factors combinations are evaluated, and the relationship between the computed efficiency scores and a single performance criterion of DMUs is investigated using decision tree. Based on the results of decision tree analysis, a relatively better DEA model can be chosen, which is expected to well represent the true performance of DMUs. We illustrate the effectiveness of the proposed method by applying it to the efficiency evaluation of 101 listed companies in steel and metal industry.

Boron nitride based processing aids

  • Hatzikiriakos, Savvas G.;Rathod, Nimish
    • Korea-Australia Rheology Journal
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    • v.15 no.4
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    • pp.173-178
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    • 2003
  • Boron nitride is a new processing aid that is capable of eliminating gross melt fracture in several polymer processing operations. Its combinations with other processing aids i.e. fluoropolymers offer additional possibilities of obtaining enhanced processing aids that may take the processes to rates not realized before. A variety of different such combinations are discussed in this paper. The essential componenets are (1) boron nitride capable of eliminating gross melt fracture and (2) suitable lubricant capable of eliminating surface melt fracture such as stearates for the polyolefin processing and polyethylenes for the processing of fluoropolymers.

A Structural Isomorphism between Problems Counting the Number of Combinations (조합문제 사이의 구조적 동형)

  • Lee Ju-Young;Kim Suh-Ryung;Park Hye-Sook;Kim Wan-Soon
    • The Mathematical Education
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    • v.45 no.1 s.112
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    • pp.123-138
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    • 2006
  • In this paper, we confirm through surveys and interviews that it helps students in solving a problem counting the number of combinations to find a structural isomorphism between the given problem and a typical problem with the same mathematical structure. Then we suggest that a problem of distributing balls into boxes might be a good candidate for a typical problem. This approach is coherent to the viewpoint given by English(2004) that it is educationally important to see the connection and relationship between problems with different context but with similar mathematical structure.

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The Role of Bronchodilators in Preventing Exacerbations of Chronic Obstructive Pulmonary Disease

  • Beeh, Kai M.
    • Tuberculosis and Respiratory Diseases
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    • v.79 no.4
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    • pp.241-247
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    • 2016
  • Bronchodilators are the cornerstone of symptomatic chronic obstructive pulmonary disease (COPD) treatment. They are routinely recommended for symptom reduction, with a preference of long-acting over short-acting drugs. Bronchodilators are classified into two classes based on distinct modes of action, i.e., long-acting antimuscarinics (LAMA, once-daily and twice-daily), and long-acting ${\beta}2$-agonists (LABA, once-daily and twice-daily). In contrast to asthma management, evidence supports the efficacy of both classes of long-acting bronchodilators as monotherapy in preventing COPD exacerbations, with greater efficacy of LAMA drugs versus LABAs. Several novel LAMA/LABA fixed dose combination inhalers are currently approved for COPD maintenance treatment. These agents show superior symptom control to monotherapies, and some of these combinations have also demonstrated superior efficacy in exacerbation prevention versus monotherapies, or combinations of inhaled corticosteroids plus LABA. This review summarizes the current data on clinical effectiveness of bronchodilators alone or in combination to prevent exacerbations of COPD.

Performance Comparison of Classication Methods with the Combinations of the Imputation and Gene Selection Methods

  • Kim, Dong-Uk;Nam, Jin-Hyun;Hong, Kyung-Ha
    • The Korean Journal of Applied Statistics
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    • v.24 no.6
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    • pp.1103-1113
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    • 2011
  • Gene expression data is obtained through many stages of an experiment and errors produced during the process may cause missing values. Due to the distinctness of the data so called 'small n large p', genes have to be selected for statistical analysis, like classification analysis. For this reason, imputation and gene selection are important in a microarray data analysis. In the literature, imputation, gene selection and classification analysis have been studied respectively. However, imputation, gene selection and classification analysis are sequential processing. For this aspect, we compare the performance of classification methods after imputation and gene selection methods are applied to microarray data. Numerical simulations are carried out to evaluate the classification methods that use various combinations of the imputation and gene selection methods.

Statistical Interaction for Major Gene Combinations (우수 유전자 조합 선별을 위한 통계적 상호작용 방법비교)

  • Lee, Jea-Young;Lee, Yong-Won;Choi, Young-Jin
    • The Korean Journal of Applied Statistics
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    • v.23 no.4
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    • pp.693-703
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    • 2010
  • Diseases of human or economical traits of cattles are occured by interaction of genes. We introduce expanded multifactor dimensionality reduction(E-MDR), dummy multifactor dimensionality reduction(D-MDR) and SNPHarvester which are developed to find interaction of genes. We will select interaction of outstanding gene combinations and select final best genotype groups.

Effect of Silica Fume and Slag on Compressive Strength and Abrasion Resistance of HVFA Concrete

  • Rashad, Alaa M.;Seleem, Hosam El-Din H.;Shaheen, Amr F.
    • International Journal of Concrete Structures and Materials
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    • v.8 no.1
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    • pp.69-81
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    • 2014
  • In this study, portland cement (PC) has been partially replaced with a Class F fly ash (FA) at level of 70 % to produce high-volume FA (HVFA) concrete (F70). F70 was modified by replacing FA at levels of 10 and 20 % with silica fume (SF) and ground granulated blast-furnace slag (GGBS) and their equally combinations. All HVFA concrete types were compared to PC concrete. After curing for 7, 28, 90 and 180 days the specimens were tested in compression and abrasion. The various decomposition phases formed were identified using X-ray diffraction. The morphology of the formed hydrates was studied using scanning electron microscopy. The results indicated higher abrasion resistance of HVFA concrete blended with either SF or equally combinations of SF and GGBS, whilst lower abrasion resistance was noted in HVFA blended with GGBS.