• 제목/요약/키워드: Combination Approach

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Possibilities of Liquid Chromatography Mass Spectrometry (LC-MS)-Based Metabolomics and Lipidomics in the Authentication of Meat Products: A Mini Review

  • Harlina, Putri Widyanti;Maritha, Vevi;Musfiroh, Ida;Huda, Syamsul;Sukri, Nandi;Muchtaridi, Muchtaridi
    • 한국축산식품학회지
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    • 제42권5호
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    • pp.744-761
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    • 2022
  • The liquid chromatography mass spectrometry (LC-MS)-based metabolomic and lipidomic methodology has great sensitivity and can describe the fingerprint of metabolites and lipids in pork and beef. This approach is commonly used to identify and characterize small molecules such as metabolites and lipids, in meat products with high accuracy. Since the metabolites and lipids can be used as markers for many properties of a food, they can provide further evidence of the foods authenticity claim. Chromatography coupled to mass spectrometry is used to separate lipids and metabolites from meat samples. The research data usually is compared to lipid and metabolite databases and evaluated using multivariate statistics. LC-MS instruments directly connected to the metabolite and lipid databases software can be used to assess the authenticity of meat products. LC-MS has good selectivity and sensitivity for metabolomic and lipidomic analysis. This review highlighted the combination of metabolomics and lipidomics can be used as a reference for analyzing authentication meat products.

Factors Affecting Online Hotel Selection Behavior of Domestic Tourists: An Empirical Study from Vietnam

  • LE, Ngan Ngoc Kim;BUI, Bao Trong Tien
    • The Journal of Asian Finance, Economics and Business
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    • 제9권5호
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    • pp.187-199
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    • 2022
  • The purpose of this study was to offer a new conceptual framework based on a combination of the TPB model, the TAM model, and two additional constructs consisting of eWOM and pricing value called the E-P-TAM-TPB model, and to assess the model's implications on hotel selection behavior. This study empirically examines the E-P-TAM-TPB model to evaluate and validate domestic tourists' online hotel booking intentions by using the partial least squares structural equation modeling (PLS-SEM) approach. The data was collected from 355 domestic tourists who booked the room via the hotel website. The major findings of this study indicated that the E-P-TAM-TPB model has a positive significant influence on online hotel selection behavior. The results revealed that all proposed hypotheses were declared supported. Future studies should build on the framework by incorporating potential moderators to better understand how different groups of customers behave online in different segments of the hospitality industry. Managers must not only develop an easy booking process but also provide price value information to attract or impress clients. Tourists can compare room rates with other hotel websites and OTAs.

Effects of Korean Traditional Medicine Treatment on Spontaneous Osteonecrosis of the Knee: A Case Report

  • Lee, Soo-Kyung;Park, Eun-Young;Lee, June-Haeng;Kang, Sun-Woo;Won, Yoon-Jae;Yang, Myeong-Yeol;Ha, Jae-Joon
    • Journal of Acupuncture Research
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    • 제39권1호
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    • pp.59-63
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    • 2022
  • Spontaneous osteonecrosis of the knee (SONK) is a common form of osteonecrosis of the knee and mainly affects the medial condyle due to localized vascular insufficiency. We report a case of SONK in a 65-year-old woman who had severe knee pain in her left knee whichimpeded her capacityto walk beyond 10 minutes. Bilateral knee X-rays revealed degenerative osteoarthritis of both knees and magnetic resonance imaging revealed R/O SONK in the lateral aspect of the medial femoral condyle, as well as a medial meniscal posterior horn root tear, and a Grade 1 medial collateral ligament injury. She was hospitalized at Jaseng Hospital of Korean Medicine for 21 days and receivedcombination therapy includingacupuncture, pharmacopuncture, and herbal medicine. Patient-reported scales indicated that her pain and physical functional limitations were alleviated. Combination therapy consisting of Korean traditional medicine may bean alternative nonoperative treatment approach for patients with SONK.

병원 간호사의 조직침묵에 관한 근거이론적 접근 (Nurses' Organizational Silence in Hospitals: A Grounded Theoretical Approach)

  • 이경희;유명순
    • 한국직업건강간호학회지
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    • 제31권2호
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    • pp.66-76
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    • 2022
  • Purpose: This study aimed to explore the constructs and context of hospital nurses' organizational silence. Methods: In-depth interviews were conducted with 17 nurses in small-middle general hospitals as well as big university hospitals. We then derived the key themes using grounded theory method. Results: Nine themes and 30 sub-themes were derived: "Willing to be recognized for performance rather than saying", "Getting used to the hard-to-speak climate", "Face the reality that does not change when said", "Complicated situation that prevents self-regulating decision-making", "Conflicts that are difficult to confront", "Unfair responsibilities that I want to evade", "Leaders who don't support me", and "Being blocked in communication". Consequently, the nurses learned to adopt a climate of silence and "learned organizational silence" behavior. They experienced that prosocial silence was essential for obtaining approval as a member of the group, and defensive silence for protecting themselves in the hierarchical structure and unfair responsibilities. Acquiescent silence originated from a futile relationship with their supervisors, one-way communications, and the unsupportive management system, in which three types of silence appeared sequentially or in combination with each other. Conclusion: Based on these results, nursing managers should identify the context of nurses' organizational silence and should lessen these silence behaviors.

Current methodologies in construction of plant-pollinator network with emphasize on the application of DNA metabarcoding approach

  • Namin, Saeed Mohamadzade;Son, Minwoong;Jung, Chuleui
    • Journal of Ecology and Environment
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    • 제46권2호
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    • pp.126-135
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    • 2022
  • Background: Pollinators are important ecological elements due to their role in the maintenance of ecosystem health, wild plant reproduction, crop production and food security. The pollinator-plant interaction supports the preservation of plant and animal populations and it also improves the yield in pollination dependent crops. Having knowledge about the plant-pollinator interaction is necessary for development of pesticide risk assessment of pollinators and conservation of endangering species. Results: Traditional methods to discover the relatedness of insects and plants are based on tracing the visiting pollinators by field observations as well as palynology. These methods are time-consuming and needs expert taxonomists to identify different groups of pollinators such as insects or identify flowering plants through palynology. With pace of technology, using molecular methods become popular in identification and classification of organisms. DNA metabarcoding, which is the combination of DNA barcoding and high throughput sequencing, can be applied as an alternative method in identification of mixed origin environmental samples such as pollen loads attached to the body of insects and has been used in DNA-based discovery of plant-pollinator relationship. Conclusions: DNA metabarcoding is practical for plant-pollinator studies, however, lack of reference sequence in online databases, taxonomic resolution, universality of primers are the most crucial limitations. Using multiple molecular markers is preferable due to the limitations of developed universal primers, which improves taxa richness and taxonomic resolution of the studied community.

Seismic performance evaluation of steel moment resisting frames with mid-span rigid rocking cores

  • Ali Akbari;Ali Massumi;Mark Grigorian
    • Steel and Composite Structures
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    • 제46권5호
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    • pp.621-635
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    • 2023
  • The combination of replaceable and repairable properties in structures has introduced new approach called "Low Damage Design Structures". These structural systems are designed in such a way that through self-centering, primary members and specific connections neither suffer damage nor experience permanent deformations after being exposed to severe earthquakes. The purpose of this study is the seismic assessment of steel moment resisting frames with the aid of rigid rocking cores. To this end, three steel moment resisting frames of 4-, 8-, and 12-story buildings with and without rocking cores were developed. The nonlinear static analysis and incremental dynamic analysis were performed by considering the effects of the vertical and horizontal components of 16 strong ground motions, including far-fault and near-fault arrays. The results reveal that rocking systems benefit from better seismic performance and energy dissipation compared to moment resisting frames and thus structures experience a lower level of damage under higher intensity measures. The analyses show that the interstory drift in structures equipped with stiff rocking cores is more uniform in static and dynamic analyses. A uniform interstory drift distribution leads to a uniform distribution of the bending moment and a reduction in the structure's total weight and future maintenance costs.

Form-finding of lifting self-forming GFRP elastic gridshells based on machine learning interpretability methods

  • Soheila, Kookalani;Sandy, Nyunn;Sheng, Xiang
    • Structural Engineering and Mechanics
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    • 제84권5호
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    • pp.605-618
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    • 2022
  • Glass fiber reinforced polymer (GFRP) elastic gridshells consist of long continuous GFRP tubes that form elastic deformations. In this paper, a method for the form-finding of gridshell structures is presented based on the interpretable machine learning (ML) approaches. A comparative study is conducted on several ML algorithms, including support vector regression (SVR), K-nearest neighbors (KNN), decision tree (DT), random forest (RF), AdaBoost, XGBoost, category boosting (CatBoost), and light gradient boosting machine (LightGBM). A numerical example is presented using a standard double-hump gridshell considering two characteristics of deformation as objective functions. The combination of the grid search approach and k-fold cross-validation (CV) is implemented for fine-tuning the parameters of ML models. The results of the comparative study indicate that the LightGBM model presents the highest prediction accuracy. Finally, interpretable ML approaches, including Shapely additive explanations (SHAP), partial dependence plot (PDP), and accumulated local effects (ALE), are applied to explain the predictions of the ML model since it is essential to understand the effect of various values of input parameters on objective functions. As a result of interpretability approaches, an optimum gridshell structure is obtained and new opportunities are verified for form-finding investigation of GFRP elastic gridshells during lifting construction.

Gaussian process regression model to predict factor of safety of slope stability

  • Arsalan, Mahmoodzadeh;Hamid Reza, Nejati;Nafiseh, Rezaie;Adil Hussein, Mohammed;Hawkar Hashim, Ibrahim;Mokhtar, Mohammadi;Shima, Rashidi
    • Geomechanics and Engineering
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    • 제31권5호
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    • pp.453-460
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    • 2022
  • It is essential for geotechnical engineers to conduct studies and make predictions about the stability of slopes, since collapse of a slope may result in catastrophic events. The Gaussian process regression (GPR) approach was carried out for the purpose of predicting the factor of safety (FOS) of the slopes in the study that was presented here. The model makes use of a total of 327 slope cases from Iran, each of which has a unique combination of geometric and shear strength parameters that were analyzed by PLAXIS software in order to determine their FOS. The K-fold (K = 5) technique of cross-validation (CV) was used in order to conduct an analysis of the accuracy of the models' predictions. In conclusion, the GPR model showed excellent ability in the prediction of FOS of slope stability, with an R2 value of 0.8355, RMSE value of 0.1372, and MAPE value of 6.6389%, respectively. According to the results of the sensitivity analysis, the characteristics (friction angle) and (unit weight) are, in descending order, the most effective, the next most effective, and the least effective parameters for determining slope stability.

XML-based Information Model for Interactive Electronic Technical Manual for Urban Regeneration Project

  • Sunghoon Kang;Hyun-Soo Lee;Moonseo Park;Jin-Wook Jung
    • 국제학술발표논문집
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    • The 3th International Conference on Construction Engineering and Project Management
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    • pp.841-846
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    • 2009
  • Recently, the construction industry is getting more complex and sophisticated having the characteristics of a mega project. Mega project pursues a value that can't be gained with an approach of seeing a project as just a simple sum of different parts but a mutual combination. However, the current manuals can't fulfill the needs for supporting, therefore, need a tool to support the decision making and an IETM is expected to take this role. Despite the a lot of expected advantages of IETM, it is still difficult to apply because of the frequent changes of information of detailed process and its complexity. In this research, as part of developing an IETM, we aim to propose a system frame which is based on the analysis of processes of a project. It is basic part of IETM to give information to users and IETM consists of normal mode that offers general information about the urban regeneration project and user-specified mode that gives classified and reorganized information to user. For supporting these functions, IETM should be stored in a form that can classify the information about urban regeneration project and be tagged with meaningful tags. Moreover IETM developers have to consider the interoperability of IETM because it ultimately should be coordinated with overall Project Management System like an iPMIS. We used XML for solution of interoperability because it stores information as just text-file that doesn't need a special form.

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A novel hybrid control of M-TMD energy configuration for composite buildings

  • ZY Chen;Yahui Meng;Ruei-Yuan Wang;T. Chen
    • Steel and Composite Structures
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    • 제48권4호
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    • pp.475-483
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    • 2023
  • In this paper, a new energy-efficient semi-active hybrid bulk damper is developed that is cost-effective for use in structural applications. In this work, the possibility of active and semi-active component configurations combined with suitable control algorithms, especially vibration control methods, is explored. The equations of motion for a container bridge equipped with an MDOF Mass Tuned Damper (M-TMD) system are established, and the combination of excitation, adhesion, and control effects are performed by a proprietary package and commercial custom submodel software. Systematic methods for the synthesis of structural components and active systems have been used in many applications because of the main interest in designing efficient devices and high-performance structural systems. A rational strategy can be established by properly controlling the master injection frequency parameter. Simulation results show that the multiscale model approach is achieved and meets accuracy with high computational efficiency. The M-TMD system can significantly improve the overall response of constrained structures by modestly reducing the critical stress amplitude of the frame. This design can be believed to build affordable, safe, environmentally friendly, resilient, sustainable infrastructure and transportation.