• Tuberculosis and Respiratory Diseases
• /
• 제67권2호
• /
• pp.131-134
• /
• 2009

Pulmonary papillomas are rare benign epithelial neoplasms arising in bronchial surface epithelium. They are categorized by a variety of cell types including squamous, glandular, and mixed squamous and glandular type. Among them, glandular papilloma is extremely rare and has not been reported in Korea. The patient was a 52 year-old man presenting with a 4-months' history of recurrent hemoptysis. Bronchofiberoscopy revealed a whitish, glistening, and polypoid mass lesion at the proximal bronchus in the basal segment of the left lower lung. Bronchoscopic biopsy was performed; papillary fronds lined by ciliated or nonciliated pseudostratified columnar epithelium were noted on histologic findings. We present the first case of glandular papilloma in Korea. Two years later, the patient visited our hospital again due to hemoptysis. On follow-up bronchoscopy, a mass that had been found previously showed an increase in size.

• Asian-Australasian Journal of Animal Sciences
• /
• 제15권6호
• /
• pp.783-788
• /
• 2002

Bovine yolk sac at day 24 of pregnancy, and placental membranes (chorion and allantois) from days 70 and 100 of pregnancy were isolated and cultured in a modified minimum essential medium in the presence of $[^{35}S]$methionine. Proteins synthesized and secreted by isolated bovine yolk sac, chorion and allantois were analyzed by fluorography of two-dimensional polyacrylamide gel electrophoresis. Serum-like proteins,transferrin, ${\alpha}$-fetoprotein, ${\alpha}$1-antitrypsin and ${\alpha}$1-acid glycoprotein,were the major protein products of yolk sac. A 21 kDa protein produced by yolk sac was identified immunochemically as retinol-binding protein (RBP). Chorion and allantios from days 70 and 100 of pregnancy were active in protein synthesis and secretion. Both chorion and allantois did not secret serum-like proteins but secreted a number of neutral-to-acidic proteins including RBP. Secretory proteins produced by the yolk sac, chorion and allantois may play important roles in the embryonic development and the successful outcome of pregnancy. Antiserum against bovine placental RBP was employed to the immunocytochemistry by immunoperoxidase method. Immunoreactive RBP was localized in epithelial cells and island-like cell clones of yolk sac. Immunostaining for RBP was detected in simple columnar epithelium of chorion and in simple squamous epithelium of allantois. In the present study, proteins synthesized and secreted by yolk sac at day 24 of pregnancy, chorion and allantois from days 70 and 100 of pregnancy were characterized In addition, RBP was localized in yolk sac, chorion and allantois by immunoperoxidase method. The immunoperoxidase method has been proven to be a very effective technique to identify the cellular source of protein synthesis in extraembryonic membranes.

• 한국패류학회지
• /
• 제12권1호
• /
• pp.1-17
• /
• 1996

Morphological and histochemical characteristics of the cells in posterior tentacle antenna of Korean slug, Incilaria fruhstorferi were observed with light microscope. The epithelium of the posterior tentacle antenna was composed of supporting cells, sensory neurons and type-a clear cell. The columnar supporting epithelium was widely distributed in the posterior tentacle antenna, and the upper end of the cell was covered with acidic mucopolysaccharide. Nerve endings of the sensory neuron were distributed between type-a clear cells. It was usually located in tentacular knob, and the number of them gradually decrdased as close as tentacular stalk. Several cilia were observed on the nerve ending. Type-a clear cells were very brightly stained with all staining used, and the neutral mucous guanules distributed in the cytoplasm. Collar cells, type-b clear cell and various types of secrdtory cells distributed in the connective tissue. The collar cells were clustering in connective tissue, and the cytoplasm were filled with neutral mucous guanules. The cells and granules were stained with dark brown by silver nitrate stain. Type-b clear cells were irregular in shape and their cytoplasms were brightly stained wth many stains used. Ten types of secretory cells evenly distributed in the connective tissue and muscle layers of the posterior tentacle antenna. The five types of the secretory cells(A, B, E, J and L)seemed to secrete acidic mucopolysaccharide, and the other five type of the cell(C, D, F, H, and L)seemed to secrete neutral mucopolysaccharide. Muscular tissue composed of well-developed thick longitudinal muscle layers and thin circular muscle layers. Type-L secretory cells clustered only in muscular layers and they contained acidic mucopolysaccharides.

• Restorative Dentistry and Endodontics
• /
• 제25권2호
• /
• pp.289-298
• /
• 2000

Carbamide peroxide is usually used for vital teeth bleaching at home. Complications such as tooth hypersensitivity and/or gingival irritation are frequently reported. Therefore, this study was performed to evaluate any possible histological changes in pulp and periodontal tissue by carbamide peroxide bleaching gel in rats. 10% and 15% carbamide peroxide containing nightguard for upper molar were worn for 4 hours a day. The rats were sacrificed after 1 day, 2 days, 3 days, 4 days and 6 days application of carbamide peroxide respectively. The results were as follows : Mild infiltration of inflammatory changes below the junctional epithelium and hyperplasia of epithelium were observed in both 10% and 15% carbamide peroxide treated groups. In all experimental groups, odontoblasts were changed from columnar to cuboidal shape and/or obliterated and the focal loss of predentin was observed in pulp horn. With increasing time of application, these changes were more remarkable, but limited in pulp horn. Inflammatory reactions, vacuolar changes and hyaline degenerations of the pup tissue were also observed in some cases. These results suggested that carbamide peroxide gel used in home bleaching could cause reversible pulpal irritation.

• Clinical and Experimental Pediatrics
• /
• 제49권9호
• /
• pp.1005-1009
• /
• 2006

아가미틈새(branchial cleft) 낭종은 흔히 경부측면에 위치하나, 아가미틈새 낭종의 조직학적 소견을 보이는 낭종이 비전형적인 위치에서 발견되기도 한다. 갑상샘의 아가미틈새양(branchial cleft-like) 낭종은 이제까지 보고된 14례 중 7세 여아에서 발견된 1례를 제외하고는 모두 성인에서 발견되었다. 저자들은 좌측경부의 종물을 주소로 내원한 신생아에서 초음파 검사, 컴퓨터 단층촬영, 병리조직학 검사를 통하여 진단된 갑상샘의 아가미틈새양 낭종 1례를 경험하였기에 보고하는 바이다.

• Applied Microscopy
• /
• 제19권1호
• /
• pp.59-69
• /
• 1989

Ultrastructure of the secretory portion of the small ampullate gland in the orb web spider, Nephila clavata, has been investigated using the electron microscope. The secretory portion of this gland comprise two different regions which are a S-shaped storage sac and a long, convoluted tail. By the internal textures of the secretory granules, the sac is subdivided into two regions ; the proximal region near the tail and the distal region near the duct. Commonly single layered connectives cover the basal portion of the sac epithelium, and apical portion of the epithelial cells is occupied by the thick cuticles. Within the epithelial cells of both the proximal and distal region, several types of the secretory granules surrounded by a limiting membrane and had characteristic crystalloid are scattered throughout the cytoplasm. The granular size and its electron densities are not coincide with each other according to the maturation level of the granules. The wall of the tail is composed of single layer of columnar epithelial cells, and their nuclei are found at the basal portion of the cells. Dissimilar to the epithelial cells of the sac, apical cuticles are not found at this portion. In the cytoplasm of these cells, numerous secretory granules, synthesized from the rough endoplasmic reticula commonly and had fine fibrous materials, are found. At the cell surface bordering the lumen, microvilli are seen, arid along the cellular boundaries specialized septate junctions and desmosomes appeared.

• Journal of Chest Surgery
• /
• 제11권3호
• /
• pp.246-252
• /
• 1978

A three year and seven month old girl with moderate depression deformity of the sternum associated with a huge well defined homogenous hazy mass density of the upper half of the right hemithorax on plain chest x-ray had developed, exertionaI dyspnea (Figs1, 2 and 3). Correction of the funnel chest was carried out with modified Ravitch procedure and resection of the intrathoracic cystic mass was performed through an anterolateral thoracotomy incision in one stage operation satisfactorily (Figs. 7 and 8). On exploration, the mass, $15{\times}12{\times}10$cm in size, was connected to the bronchus at 1cm a bove the carina by a stalk (Fig. 4). The outer surface showed abundant vasculature. The specimen was filled with mucoid material; the inner surface was much trabeculated. glistening and smooth (Fig. 5 and 6). yficroscopically, the cyst was lined with simple or pseudostratified ciliated columnar epithelium. The cystic wall was composed of loose fibrous connective tissue, muscle layers, cartilages with some lymphocytic infiltration (Fig. 9). Isolated cases of funnel chest deformity and congenital bronchogenic cystic disease are not uncommon; however, the assocbtion of the two conditions is yery rare. Therefore. report and review of the literature was done.

• Journal of Korean Neurosurgical Society
• /
• 제57권2호
• /
• pp.135-139
• /
• 2015

Spinal neurenteric cysts are uncommon congenital lesions, furthermore solitary neurenteric cysts of the upper cervical spine are very rare. A 15-year-old boy having an intraspinal neurenteric cyst located at cervical spine presented with symptoms of neck pain and both shoulders pain for 2 months. Cervical spine magnetic resonance (MR) imaging demonstrated an intradural extramedullary cystic mass at the C1-3 level without enhancement after gadolinium injection. There was no associated malformation on the MR imaging, computed tomography, and radiography. Hemilaminectomy at the C1-3 levels was performed and the lesion was completely removed through a posterior approach. Histological examination showed the cystic wall lined with ciliated pseudostratified columnar epithelium containing mucinous contents. Neurenteric cyst should be considered in the diagnosis of spinal solitary cystic mass.

• Journal of Korean Neurosurgical Society
• /
• 제52권1호
• /
• pp.67-70
• /
• 2012

We report a rare case of a spinal intramedullary ependymal cyst in a 46-year-old female and review the 17 pathologically proven cases in the literature. The patient presented with a two-week history of gradually increasing tingling in her left posterior thigh and calf. A preoperative magnetic resonance image revealed a well-defined intramedullary cystic lesion on the ventral side of the spinal cord at the T11 to T12 levels. The lesion was hyper intense in T2-weighted images and hypointense in T1-weighted. The patient underwent a right-side hemilaminectomy at the T11 to T12 levels and fenestration of the cyst wall. After having the cyst wall partially removed and communication established between the cyst and the subarachnoid space, the patient improved neurologically. A histological study of the surgical specimens revealed that the cyst wall consisted of glial cells lined by a simple cuboidal to columnar epithelium. An immunohistochemical examination of the cells lining the cyst wall was positive for S-100 protein, glial fibrillary acidic protein, epithelial membrane antigen, and cytokeratin. We suggest that the optimal treatment of intramedullary ependymal cysts creates adequate communication between the cyst and the subarachnoid space.

• 한국패류학회지
• /
• 제19권2호
• /
• pp.81-87
• /
• 2003

참전복 (Haliotis discus hannai) 의 소화관은 치설낭, 식도, 소낭, 위, 장(전장, 중장, 후장), 항문과 부속기관인 간췌장으로 구성되어 있었다. 소화관 상피층은 원주형 섬모상피, 점액세포 및 과립세포들로 구성되어있었으며, 상피층의 두께는 소낭이 90.80 ${\mu}$m로 가장 두꺼웠다. 점막상피에서 점액세포가 차지하는 면적은 식도에서 가장 높았으며, 점액세포의 점액물질은 식도, 전장, 중장, 후장에서는 산성 및 중성의 뮤코다당류였으며, 소낭과 위의 점액물질은 지방성분으로 조사되었다.