• 한국산업정보학회논문지
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• 제13권2호
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• pp.69-79
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• 2008

무선 인터넷과 모바일 기기의 보급으로 언제 어디서나 원하는 정보를 얻을 수 있는 유비쿼터스 환경을 위한 인프라가 구축되면서 교육을 포함한 다양한 분야에서 오프라인과 온라인 컨텐츠를 동시에 이용함으로써 정보 전달의 효율성을 높일 수 있는 방법에 대한 연구가 활발하게 이루어지고 있다. 본 논문은 사용자에게 모바일 기기를 이용하여 오프라인과 온라인 컨텐츠를 함께 제공하여 교육의 효과를 높일 수 있는 혼합형 모바일 교육 시스템(Mixed Mobile Education System: MME)을 제안한다. 제안된 시스템은 기존의 연구와 달리 사용자에게 자연스러운 환경을 제공하기 위해서 부가적인 태그를 사용하지 않는다. 태그를 사용하는 시스템의 경우 새로운 데이터의 등록이 어렵고 유사한 내용의 오프라인 컨텐츠 사용이 불가능하기 때문이다. 본 논문에서 우리는 저화질의 카메라를 통해 입력받은 영상에서 잡음 색상 왜곡, 크기 및 기울기 변화에 영향을 적게 받는 특징점을 추출하고 오프라인 컨텐츠를 인식하기 위해 Scale Invariant Feature Transform(SIFT) 알고리즘을 사용하였다. 또한 클라이언트-서버 구조를 사용함으로써 모바일 장치의 제한적인 저장 능력 문제를 해결하고 데이터의 등록 및 수정이 용이하도록 하였다. 실험을 통해 기존의 흔합형 교육 시스템과의 성능을 비교하고 제안된 시스템의 장단점을 확인하였으며, 시스템을 실생활에 적용하였을 경우 다양한 상황에서도 사용자에게 만족할만한 성능을 제공함을 확인하였다.

• 비교문화연구
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• 제28권
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• pp.17-36
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• 2012

This essay places the South Korean film Thirst (2009) within Park Chan-wook's oeuvre as a filmmaker notorious for graphic depictions of violence and revenge. Park's use of dark humour in his films, which is emphasized in Thirst perhaps more than ever, allows for a more self-aware depiction of violence, where both the viewer and the protagonist are awakened to the futility of revenge. This ultimately paints his characters as fascinatingly crazy - simultaneously heroes, villains, and victims. Film theorist Wes D. Gehring's three themes of dark humour ('man as beast,' 'the absurdity of the world,' and 'the omnipresence of death') become most obvious in Park's most recent film, which pays closer attention to character development through narrative detail. Rather than portraying the characters as sentimental, dark humour depicts their misfortunes in an alternative way, allowing for consideration of such taboo subjects as religion, adultery, and death/suicide. These issues are further tackled through Thirst's portrayal of its vampire protagonist, which ultimately de-mystifies the traditional vampire figure. While this character has more often been associated with romance, exoticism and the mystical powers of the supernatural, Thirst takes relatively little from the demons of Nosferatu (Murnau, 1922) and various other Dracula adaptations, nor the romantic figures of Interview with the Vampire (Jordan, 1994), and Twilight (Hardwicke, 2008). Instead, it is part of a much smaller group of contemporary vampire films, which are rather informed by a postmodern reconfiguration of the monster. Thus, this paper examines Thirst as an important contribution to the global and hybrid nature of those films in which postmodern vampires are sympathetic and de-mystified, exhibiting symptoms stemming from a natural illness or misfortune. Park's undertaking of a vampire film allows for a complex balance between narrative and visuals through his focus on the Western implications of this myth within Korean cinema. This combination of international references and traditional Korean culture marks it as highly conscious of New Korean Cinema's focus on globalization. With Thirst, Park successfully unites familiar images of the vampire hunting and feeding, with more stylistically distinct, grotesque images of violence and revenge. In this sense, dark humour highlights the less charming aspects of the vampire struggling to survive, most effective in scenes depicting the protagonist feeding from his friend's IV in the hospital, and sitting in the sunlight, slowly turning to ash, in the final minutes of the film. The international appeal of Park's style, combining conventions of the horror/thriller genre with his own mixture of dark humour and non-linear narrative, is epitomized in Thirst, which underscores South Korea's growing global interest with its overt international framework. Furthermore, he portrayal of the vampire as a sympathetic figure allows for a shift away from the conventional focus on myth and the exotic, toward a renewed construction of the vampire in terms of its contribution to generic hybridization and cultural adaptation.

• Journal of the Korean Wood Science and Technology
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• 제30권2호
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• pp.128-133
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• 2002

본 연구는 동절기(1월 중순)에 벌채된 후 목재집하장으로 운반되어 야적장에 저목 중인 소나무와 잣나무 원목을 대상으로 변재변색의 발생시기와 변색 특성을 조사하기 위하여 수행되었다. 벌채 후 3, 4, 5, 6, 8개월 경과시 변색 평가를 실시하였는데, 매 평가시 원목 3개를 임의로 선정하여 원목당 수축방향에 대해 일정 간격으로 7~9개의 두께 3 cm 원판을 채취하여 변색 원인균을 분리한 후 변재변색의 방사방향 최대 침투깊이와 % 변색율을 측정하였다. 변재변색은 전적으로 충형변색이었으며, 주요 변색원인균인 Ophiostomatoid 균을 매개하는 수피천공충은 소나무좀으로 확인되었다. 소나무와 잣나무 원목은 5월 이전까지는 변재변색의 위험없이 저목할 수 있으나 5월 이후부터는 원목의 변재변색이 급속하게 증가하였다. 변색의 정도는 소나무보다 잣나무에서 심하였으며, 장마철 저목 중에 소나무 원목에서 개떡버섯과 치마버섯의 자실체를 다수 관찰할 수 있었다. 본 연구를 통해 밝혀진 결과들은 앞으로 동절기에 벌채되어 저목 중인 소나무와 잣나무 원목에 발생하는 변재변색을 예방하기 위한 제반 조치를 취하는데 매우 중요한 자료로 사용될 것이다.

• 광물과 암석
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• 제35권3호
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• pp.199-214
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• 2022

영남육괴는 광역적인 고온-저압의 변성작용과 부분용융을 경험한 한반도 지각을 대표하는 기반암 중 하나이다. 이 논문에서는 지금까지 보고된 영남육괴 고온 변성암류에 기록된 백립암상의 변성작용과 부분용융 과정을 통해 고원생대(1.87-1.84Ga)의 고온조산운동 기록을 살펴본다. 특히 열원으로서의 역할을 담당했던, 산청-하동지역 회장암질 마그마를 비롯한 고철질 화성활동과 고온-저압 변성작용 사이의 시공간적 연계는 영남육괴의 광역변성작용과 지각용융을 이해하는데 필수적인 정보를 제공한다. 지각용융은 주로 함(含)유체 부분용융과 백운모/흑운모의 탈수용융에 의해 발생하였으며, 다양한 형태의 우백대와 우백질 화강암을 형성하였다. 이차이온질량분석기를 활용한 저어콘과 모나자이트의 암석연대학적 결과는 영남육괴의 고온변성작용과 부분용융이 약 1870-1854 Ma의 ~15 Ma 기간 동안 지속되었음을 지시한다. 또한, 초기 차노카이트로 대표되는 유체유입 사건이 약 1840 Ma에 발생하였다. 이와 같이 영남육괴 내에는 고온변성작용과 부분융용, 그리고 유체유입이라는 고온조산대를 대표하는 일련의 지질사건들이 기록되어 있다. 영남육괴에서 확인된 고온조산대는 북중국 지괴에서 흔히 보고되는 고원생대 조산운동과 연계되어 있으며, 고원생대 콜럼비아/누나 초대륙 진화의 최후기 산물이리라 판단된다.

• 대한토목학회논문집
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• 제26권3B호
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• pp.279-289
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• 2006

최근에 수문시계열로부터 저차원의 비선형 거동을 재구성하고자 하는 연구가 활발히 진행되고 있다. 이러한 관점에서 본 연구에서는 Support Vector Machine(SVM)을 이용하여 우수한 상태-공간 재구성 능력을 갖는 비선형 예측모형을 구성하여 Great Salt Lake(GSL) Volume에 적용하였다. SVM은 Kernel 함수로부터 유도된 고차원의 특성공간 안에서 선형함수의 가상공간을 이용하는 Machine Learning 방법론이다. 또한 SVM은 훈련자료로부터 얻어지는 평균제곱오차가 아닌 일반화된 오차를 최소화함으로써 상대적으로 기존 방법에 비해 적은 수의 매개변수와 과적합(over fitting)을 피하면서 비선형 함수의 최적화가 가능하다. 본 연구에서 제시한 SVM 회귀분석의 적용성은 미국의 GSL의 2주 간격 Volume을 대상으로 검토하였다. SVM을 이용한 비선형 예측모형은 GSL Volume의 2주(1-Step), 8주(4-Step)와 반복예측(Iterated Prediction, 121-Step)까지 적용되었다. 본 연구에서는 극치사상 즉, 급격한 감소 및 증가 구간을 예측하는데 있어서 훈련구간과 예측구간을 구분하여 모형의 신뢰성을 평가하였다. 예측결과SVM은 훈련자료로부터 적은 수의 관측치를 이용하여 동역학적 거동을 추출할 수 있었으며 실제 관측자료와 거의 유사한 예측이 가능함을 통계적 지표로 확인할 수 있었다. 따라서 비선형 수문시계열의 단기 예측을 위한 모형으로 적용이 가능할 것으로 판단된다.

• Korean Journal of Radiology
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• 제24권11호
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• pp.1102-1113
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• 2023

Objective: To elucidate the use of radiological studies, including nuclear medicine, and biopsy for the diagnosis and staging of prostate cancer (PCA) in clinical practice and understand the current status of PCA in Asian countries via an international survey. Materials and Methods: The Asian Prostate Imaging Working Group designed a survey questionnaire with four domains focused on prostate magnetic resonance imaging (MRI), other prostate imaging, prostate biopsy, and PCA backgrounds. The questionnaire was sent to 111 members of professional affiliations in Korea, Japan, Singapore, and Taiwan who were representatives of their working hospitals, and their responses were analyzed. Results: This survey had a response rate of 97.3% (108/111). The rates of using 3T scanners, antispasmodic agents, laxative drugs, and prostate imaging-reporting and data system reporting for prostate MRI were 21.6%-78.9%, 22.2%-84.2%, 2.3%-26.3%, and 59.5%-100%, respectively. Respondents reported using the highest b-values of 800-2000 sec/mm² and fields of view of 9-30 cm. The prostate MRI examinations per month ranged from 1 to 600, and they were most commonly indicated for biopsy-naïve patients suspected of PCA in Japan and Singapore and staging of proven PCA in Korea and Taiwan. The most commonly used radiotracers for prostate positron emission tomography are prostate-specific membrane antigen in Singapore and fluorodeoxyglucose in three other countries. The most common timing for prostate MRI was before biopsy (29.9%). Prostate-targeted biopsies were performed in 63.8% of hospitals, usually by MRI-ultrasound fusion approach. The most common presentation was localized PCA in all four countries, and it was usually treated with radical prostatectomy. Conclusion: This survey showed the diverse technical details and the availability of imaging and biopsy in the evaluation of PCA. This suggests the need for an educational program for Asian radiologists to promote standardized evidence-based imaging approaches for the diagnosis and staging of PCA.

• 대한화학회지
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• 제68권3호
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• pp.151-159
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• 2024

Indian spices are well known for their numerous health benefits, flavour, taste, and colour. Recent Advancements in chemical technology have led to better extraction and identification of bioactive molecules (phytochemicals) from spices. The therapeutic effects of spices against diabetes, cardiac problems, and various cancers has been well established. The present in silico study aims to investigate the binding affinity of 29 phytochemicals from 11 Indian spices with two prominent proteins, BCL3 and CXCL10 involved in invasiveness and bone metastasis of breast cancer. The three-dimensional structures of 29 phytochemicals were extracted from PubChem database. Protein Data Bank was used to retrieve the 3D structures of BCL3 and CXCL10 proteins. The drug-likeness and other properties of compounds were analysed by ADME and Lipinski rule of five (RO5). All computational simulations were carried out using Autodock 4.0 on Windows platform. The proteins were set to be rigid and compounds were kept free to rotate. In-silico study demonstrated a strong complex formation (positive binding constants and negative binding energy ΔG) between all phytochemicals and target proteins. However, piperine and sesamolin demonstrated high binding constants with BCL3 (50.681 × 10³ mol^-1, 137.76 × 10³ mol^-1) and CXCL10 (98.71 × 10³ mol^-1, 861.7 × 10³ mol^-1), respectively. The potential of these two phytochemicals as a drug candidate was highlighted by their binding energy of -6.5 kcal mol^-1, -7.1 kcal mol^-1 with BCL3 and -6.9 kcal mol^-1, -8.2 kcal mol^-1 with CXCL10, respectively coupled with their favourable drug likeliness and pharmacokinetics properties. These findings underscore the potential of piperine and sesamolin as drug candidates for inhibiting invasiveness and regulating breast cancer metastasis. However, further validation through in vitro and in vivo studies is necessary to confirm the in silico results and evaluate their clinical potential.

• 한국환경생태학회지
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• 제16권1호
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• pp.34-45
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• 2002

강화도 남단 갯벌에 도래하는 물새류는 여차리, 동막리, 선두리 및 동검리 갯벌에서 종수 및 개체수에 차이를 나타냈다. 3월과 9월에 조사된 물새류는 다른 지역보다 여차리 갯벌에서 보다 많은 종수 및 개체수가 관찰되었다. 물새류 중에서 우점종은 민물도요(Calidris alpina)로 나타났으며, 다른 지역보다 여차리 갯벌에서 개체수가 42.0~79.1%의 점유율을 보였다. 동막리 갯벌 조간대상부가 해수면에 잠겼을 경우 여차리 갯벌에 남아있는 갯벌 면적은 0.0317$\textrm{km}^2$로서 여차리 갯벌에서 이들 면적이 휴식공간으로 활용되었다. 각 지역의 갯벌 조간대에 서식하고 있는 물새류의 잠재적 식이물의 습중생물량(wet biomass)은 여차리 갯벌에서 선두 4리 지역보다 2. 5배, 동검리와 동막리 갯벌보다 각각 1.6배와 2배가 높게 나타났다. 종수 및 개체수(/0.078$m^2$)는 여차리 갯벌에서 최대 23종 및 266개체가 출현하여, 선두4리 갯벌의 10종 및 184개체, 동검리 갯벌의 11종 33개체와 동막리 갯벌의 20종 및 69개체가 출현한 것보다 높게 나타났다. 우점종인 민물도요(38.11g)의 하루 최저 취식량은 1,295 마리이고, 먹이는 주로 왕좁쌀무늬고둥(Reticunassa festiva), 서해비단고둥(Umbonium thomasi)등의 고둥류와 두토막눈썹참갯지렁이(Perinereis aibuhitensis)였으며, 고둥류는 다른 지역보다 여차리 갯벌에서 높은 서식밀도를 나타냈다. 갯벌에 도래하는 물새류는 잠재적 식이물인 저서생물의 분포, 휴식공간의 확보, 선호하는 먹이의 분포 및 일일 취식량을 충족시켜 줄 수 있는 먹이가 풍부한 서식지 등과 밀접한 관계를 갖고 있는 것으로 나타났다. 이들 물새류의 보호를 위해서는 먹이원이 풍부하게 살아 갈 수 있는 갯벌 환경을 유지해야 한다. 갯벌의 무분별한 개발 및 매립, 방문 및 생물채취 등은 자제되어야 하며, 갯벌 환경교육 지역전문가 및 갯벌 관리프로그램 등이 개발되어야 한다.

• 대한간호학회지
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• 제11권2호
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• pp.5-8
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• 1981

This study concerns itself with the development of a new model of comprehensive health service for rural communities of Korea. The study was conceived to resolve the problems of both underservice in rural communities and underutilization of valuable health manpower, namely the nurses, the disenchanted elite health personnel in Korea. On review of the current situation, the greatest deficiencies in the Korean health care system were found in the availability of primary care at the peripheries of md communities, in the dissemination of knowledge of disease prevention and health care, and in the induction of and guidance for active participation by the clientele in health maintenance at the personal, family and community level Abundant untapped health resources were identified that could be brough to bear upon the national effort to extend health services to every member of the Korean Population. Therefore, it was Postulated that the problem of underservice in rural communities of Korea can be structurcturally resolved by the effective mobilization and organization of untapped health resources, and that. a primary care Nursing Service System offers the best possibility for fulfillment of rural health service goals within the current health man-power situation. In order to identify appropriate strategies to combat the present difficulties in Korean rural health services and to utilize nurses and other health personnel in community-centered health programs, a search was made for examples of innovative service models throughout the world. An extensive literature survey and field visits to project sites both in Korea and in the United States were made. Experts in the field of world health, health service, planners, administrators, and medical and nursing practitioners in Korea, in the United States as well as visitors from other Asian countries were widely consulted. On the basis of information and inputs from these experts a new rural health service model has been constructed within the conceptual framework of community development, especially of the innovation diffusion Model. It is considered especially important that citizens in each community develop capacities for self-care with assistance and supports from available health professionals and participate in health service-related decisions that affect their own well-being. The proposed model is based upon the regionalization of health care planning utilizing a comprehensive Nursing Service System at the immediate delivery level The model features: (1) a health administration unit at each administrative level; (2) mechanisms for community participation; (3) a continuous source of primary health care at the local community level; (4) relative centralization of specialty care and provision of tertiary or super-specialty care only at major national metropolitan centers; and (5) a system for patient referral to the appropriate level of care. This model has been built around professional nurses as the key community health workers because their training is particularly suited and because large numbers of well-trained nurses are currently available and being trained. The special element in this model is a professional nurse-guided, self-care facilitating primary care Community Nursing Service System. This is supported by a Nursing Extension Service as a new training and support structure. (See attached diagrams). A broad spectrum of programs was proposed for the Community Nursing Service System. These were designed to establish a balance of activities between the clinic-centered individual care component and the field activity-centered educational and supportive component of health care services. Examples of possible program alternatives and proposed guidelines for health care in specific situations were presented, as well as the roles and functions of the key health personnel within the Community Nursing Service System. This Rural Health Service Model was proposed as a real alternative to the maldistributed, inequitable, uncoordinated solo-practice, physician-centered fee-for-service health care available to Koreans today.

• Asian-Australasian Journal of Animal Sciences
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• 제9권1호
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• pp.1-25
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• 1996

The pathogenesis of atherosclerosis can not be summarized as a single process. Lipid infiltration hypothesis and endothelial injury hypothesis have been proposed and investigated. Recent developments show that there are many points of potential interactions between them and that they can actually be regarded as two phases of a single, unifying hypothesis. Among the many risk factors of atherosclerosis, plasma homocysteine and lipoprotein(a) draw a considerable interest because they are independent indicators of atherogenicity. Triglyceride (TG)-rich lipoproteins (chylomicron and VLDL) are not considered to be atherogenic but they are related to the metabolism of HDL cholesterol and indirectly related to coronary heart disease (CHD). LDL can of itself be atherogenic but the oxidative products of this lipoprotein are more detrimental. HDL cholesterol has been considered to be a favorable cholesterol. The so-called 'causalist view' claims that HDL traps excess cholesterol from cellular membranes and transfers it to TG-rich lipoproteins that are subsequently removed by hepatic receptors. In the so-called 'noncausalist view', HDL does not interfere directly with cholesterol deposition in the arterial wall but instead reflects he metabolism of TG-rich lipoproteins and their conversion to atherogenic remnants. Approximately 70-80% of the human population shows an effective feedback control mechanism in cholesterol homeostasis. Type of dietary fat has a significant effect on the lipoprotein cholesterol metabolism and atherosclerosis. Generally, saturated fatty acids elevate and PUFA lower serum cholesterol, whereas MUFA have no specific effect. EPA and DHA inhibit the synthesis of TG, VLDL and LDL, and may have favourable effects on some of the risk factors. Phospholipids, particularly lecithin, have an antiatherosclerotic effect. Essential phospholipids (EPL) may enhance the formation of polyunsaturated cholesteryl ester (CE) which is less sclerotic and more easily dispersed via enhanced hydrolysis of CE in the arterial wall. Also, neutral fecal steroid elimination may be enhanced and cholesterol absorption reduced following EPL treatment. Antioxidants protect lipoproteins from oxidation, and cells from the injury of toxic, oxidized LDL. The rationale for lowering of serum cholesterol is the strong association between elevation of plasma or serum cholesterol and CHD. Cholesterol-lowing, especially LDL cholesterol, to the target level could be achieved using diet and combination of drug therapy. Information on the link between cholesterol and CHD has decreased egg consumption by 16-25%. Some clinical studies have indicated that dietary cholesterol and egg have a significant hypercholesterolemic effect, while others have indicated no effect. These studies differed in the use of purified cholesterol or cholesterol in eggs, in the range of baseline and challenge cholesterol levels, in the quality and quantity of concomitant dietary fat, in the study population demographics and initial serum cholesterol levels, and clinical settings. Cholesterol content of eggs varies to a certain extent depending on the age, breed and diet of hens. However, egg yolk cholesterol level is very resistant to change because of the particular mechanism involved in yolk formation. Egg yolk contains a factor of factors responsible for accelerated cholesterol metabolism and excretion compared with crystalline cholesterol. One of these factors could be egg lecithin. Egg lecithin may not be as effective as soybean lecithin in lowering serum cholesterol level due probably to the differences of fatty acid composition. However, egg lecithin may have positive effects in hypercholesterolemia by increasing serum HDL level and excretion of fecal cholesterol. The association of serum cholesterol with egg consumption has been widely studied. When the basal or control diet contained little or no cholesterol, consumption of 1 or 2 eggs daily increased the concentration of plasma cholesterol, whereas that of the normolipemic persons on a normal diet was not significantly influenced by consuming 2 to 3 eggs daily. At higher levels of egg consumption, the concentration of HDL tends to increase as well as LDL. There exist hyper-and hypo-responders to dietary (egg) cholesterol. Identifying individuals in both categories would be useful from the point of view of nutrition guidelines. Dietary modification of fatty acid composition has been pursued as a viable method of modifying fat composition of eggs and adding value to eggs. In many cases beneficial effects of PUFA enriched eggs have been demonstrated. Generally, consumption of n-3 fatty acids enriched eggs lowered the concentration of plasma TG and total cholesterol compared to the consumption of regular eggs. Due to the highly oxidative nature of PUFA, stability of this fat is essential. The implication of hepatic lipid accumulation which was observed in hens fed on fish oils should be explored. Nutritional manipulations, such as supplementation with iodine, inhibitors of cholesterol biosynthesis, garlic products, amino acids and high fibre ingredients, have met a limited success in lowering egg cholesterol.