• 한국치위생학회지
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• 제18권5호
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• pp.797-806
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• 2018

Objectives: The purpose of this study was to analyze Influence of stress on oral health and quality of life. Methods: The participants were 172 students from 4 universities located in DaeJeon, South Korea. A questionnaire was administered, assessing the impacts of the general characteristics of the participants, temporomandibular joint (TMJ) symptoms, xerostomia, and halitosis on stress. And oral impacts on daily performance were also investigated. Data were analyzed using the Statistical Package for the Social Sciences 18.0. Results: The level of stress was higher in female, and the causes of stress was reported scholastic achievement, relations with professors, get a job. The students who were higher stress were more conscious of TMJ symptoms, xerostomia and halitosis(p<0.05). Stress was significantly positively correlated with TMJ symptoms (r=0.376, p<0.001), dry mouth (r=0.360, p<0.001), and bad breath (r=0.343, p<0.001). Oral Impacts on Daily Performance (OIDP) scores were significantly positively correlated with dry mouth, bad breath, TMJ symptoms, and stress. Regression analysis showed that 54.5% of the independent variables were related to OIDP scores. Stress and TMJ symptoms exerted a significant effect on OIDP scores. Conclusions: Stress among university students affects oral health and quality of life. Stress coping mechanisms and oral health care education programs should be developed and applied at universities.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2022년도 추계학술대회
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• pp.157-157
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• 2022

Plants being sessile are prone to various abiotic challenges, including salinity. Plants generally cope with salt stress by regulating their endogenous NO levels. NO exogenously applied in various forms also successfully impedes the salt stress, but its small size, short half life, and high volatility rate hamper its application in agriculture. NO application via CS as a nanocarrier is an alternate option to ensure the optimal kinetic release of NO for a long period compared to the free NO form. Herein, we synthesized and characterized GSNO-CS NP by ionic gelation of TPP with CS and then reacting with GSH, followed by reaction with NaNO₂ suspension. The synthesized NPs were characterized using non-destructive analytical techniques such as DLS, FTIR, and SEM to ensure their synthesis and surface morphology. NO-release profile confirmed optimal kinetic NO release for 24 h from NO-CS NP as compared to free NO form. The efficiency of NO-CS NP was checked on Arabidopsis plants under salinity stress by gauging the morphological, physiological, and enzymatic antioxidant system and SOS pathway gene expression levels. Overall, the results revealed that NO-CS NP successfully mitigates salinity stress compared to free GSNO. Concluding, the findings provide sufficient experimental evidence for the application of nanotechnology to enhance NO delivery, thus inducing more benefits for the plants under stress conditions by mitigating the deleterious impacts of salt stress on the morphological and physiological status of the plants, and regulating the ions exchange by overexpression of SOS pathway candidate genes.

• 기본간호학회지
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• 제20권4호
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• pp.419-428
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• 2013

Purpose: This study was done to explore the level of life stress, depression, and suicidal ideation and to identify the associated factors of suicidal ideation (SI) among college nursing students. Method: The design of this study was a descriptive survey design using a convenience sampling. Data collection was done using self-questionnaire from 124 students in 2 universities located in Gyeonggi and Chungnam provinces. The collected data were analyzed using descriptive statistics, ANOVA, t-test, Pearson correlation coefficients, and hierarchical multiple regression. Results: Study participants reported low level of SI, depression, and life stress ($44.45{\pm}19.21$, $8.40{\pm}5.94$, $40.65{\pm}32.17$). The 53% of variance in SI was significantly explained by life stress related value (${\beta}=.41$, p<.001), life stress related to interpersonal relationship with family (${\beta}=.19$, p=.014), life stress related to interpersonal relationship with friends (${\beta}=.34$, p<.001), and depression (${\beta}=.36$, p<.001). Conclusions: The results indicate that to decrease the SI in these students, an active interest in the students is needed to lower stress levels in interpersonal relationships with family and friends, in life stress related to value, and for relief of depression. Suicide prevention programs specific to the level of life stress and depression need to be developed for nursing students.

• Journal of Ginseng Research
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• 제43권2호
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• pp.252-260
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• 2019

Background: Increases in the average global temperature cause heat stress-induced disorders by disrupting homeostasis. Excessive heat stress triggers an imbalance in the immune system; thus protection against heat stress is important to maintain immune homeostasis. Korean ginseng (Panax ginseng Meyer) has been used as a herbal medicine and displays beneficial biological properties. Methods: We investigated the protective effects of Korean ginseng extracts (KGEs) against heat stress in a rat model. Following acclimatization for 1 week, rats were housed at room temperature for 2 weeks and then exposed to heat stress ($40^{\circ}C$/2 h/day) for 4 weeks. Rats were treated with three KGEs from the beginning of the second week to the end of the experiment. Results: Heat stress dramatically increased secretion of inflammatory factors, and this was significantly reduced in the KGE-treated groups. Levels of inflammatory factors such as heat shock protein 70, interleukin 6, inducible nitric oxide synthase, and tumor necrosis factor-alpha were increased in the spleen and muscle upon heat stress. KGEs inhibited these increases by down-regulating heat shock protein 70 and the associated nuclear $factor-{\kappa}B$ and mitogen-activated protein kinase signaling pathways. Consequently, KGEs suppressed activation of T-cells and B-cells. Conclusion: KGEs suppress the immune response upon heat stress and decrease the production of inflammatory cytokines in muscle and spleen. We suggest that KGEs protect against heat stress by inhibiting inflammation and maintaining immune homeostasis.

• 융합정보논문지
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• 제7권1호
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• pp.81-86
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• 2017

오늘날, 대학생들은 취업준비를 하면서 많은 어려움을 겪고 있다. 따라서 본 연구는 대학생들의 산업체 진출을 위한 구직준비역량과 이에 대한 대학생활 스트레스에 미치는 영향을 알아보고자 하였다. 이를 위하여 연구대상으로는 충남에 위치한 N대학교의 교양수업을 듣는 학생 158 명으로 표집하였다. 또한 분석방법으로는 연구의 목적을 위하여 대학생활 스트레스에 대한 탐색적 요인분석과 일원배치분산분석 및 상관분석을 실시하였다. 그 결과 학년에 따라서는 대학생활 스트레스와 구직준비역량은 일원배치 분석결과 통계적으로 유의미한 영향이 나타났으며, 대학생활 스트레스와 구직준비역량간의 상관관계분석 결과는 관계가 없는 것으로 나타났다. 본 연구를 통해 구직역량을 위하여 대학은 어떠한 대책을 마련해야 하는지에 대한 지속적 고민과 함께 구체적이고 체계적인 대안이 필요할 것이라고 사료된다. 또한 대학생들의 산업체에 진출할 구직역량에 대한 인식의 확대와 준비의 중요성에 대하여 시사점을 제공하고자 한다.

• 기본간호학회지
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• 제20권2호
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• pp.168-176
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• 2013

Purpose: The purpose of this study was to identify factors affecting quality of life according to Body Mass Index (BMI) of women college students. Methods: The research design was a descriptive survey design using a convenience sampling. Data were collected using self-report questionnaires. Participants were 348 women college students. Data analysis was done using SPSS/WIN 18.0 program for descriptive statistics, Pearson correlation coefficients and hierarchial multiple regression. Results: According to BMI, 3 groups of students were identified. Differences between the groups for quality of life were significant. The major factors affecting quality of life in the underweight group were departments (college), body stress and ego-resilience which explained 27.9% of the variance in quality of life. Body stress and ego-resilience were significant predictors explaining 23.1% of the variance in quality of life in the normal weight group. Ego-resilience was also a significant predictor in the overweight group explaining 15.2% of the variance in quality of life. Conclusion: Findings indicate a need to decrease body stress and strengthen ego-resilience to improve quality of life of women college students. Further studies are needed to examine nursing intervention strategies for improving quality of life for women college students.

• 디지털융복합연구
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• 제15권7호
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• pp.247-257
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• 2017

본 연구는 전문대학생의 우울 정도를 측정하고 대학생활 스트레스 요인들과 일주기성이 우울에 미치는 영향을 분석하였다. 광주지역에 소재한 전문대학교 학생 720명을 대상으로 2016년 10월 10일부터 10월 31일까지 설문조사를 실시하였으며 회수된 설문지 중 687부를 분석하였다. 연구결과 첫째, 학생들의 34.5%가 우울증 치료가 필요하며, 71.6%가 가벼운 우울증이 있는 것으로 나타났다. 둘째, 우울감은 여학생이 남학생보다 높았으며 부모와 별거시, 학년이 높을수록 높게 나타났다. 셋째, 일주기성과 우울과의 관계는 저녁활동형 일수록 우울감이 높았다. 넷째, 회귀분석 결과, 가치관으로 인한 스트레스, 일주기성, 학업스트레스, 취업스트레스 순으로 우울감에 미치는 영향이 크게 나타났다. 이러한 연구결과는 학생들의 우울증을 조기 발견하고 우울증 과 관련이 많은 스트레스 요인들을 감소시킬 수 있는 정신건강 프로그램이 필요함을 시사한다. 그러나 본 연구는 일부 지역 전문대학생에게 한정되어 있어 일반화시키기에는 무리가 있으며 향후 4년제 대학생과 전문대학생의 비교 연구가 필요하다.

• 재활간호학회지
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• 제13권2호
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• pp.114-122
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• 2010

Purpose: The purpose of this study was to identify the health promotion, stress and the quality of life and relationship between those factors in patients with genital neoplasms. Method: Data of 151 subjects with genital neoplasms were collected from August 15 to October 12, 2009 at out-patient clinic in one general hospital in Daegu. Results: The mean score of health promotion of the subjects was 1.49 (${\pm}0.53$), stress of gynecologic cancer was 1.36 (${\pm}0.76$) and the quality of life of the subjects was 2.38 (${\pm}0.59$). There was a negative correlation between the quality of life and stress (r=-.482, p<.001), and positive correlation between the quality of life and health promotion (r=.442, p<.001) in the subjects. Conclusion: This study showed correlations between the health promotion, stress and the quality of life of patients with genital neoplasms. The quality of life of the patients with genital neoplasms was low when their stress was high. In contrast, their quality of life was high when the score of health promotion was high. Considering the research findings, it is necessary to develop a health promotion program for patients with genital neoplasms to strengthen their health promotion behaviors.

• 한국발생생물학회지:발생과생식
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• 제22권3호
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• pp.235-244
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• 2018

We investigate the effect of endoplasmic reticulum (ER) stress inhibitor treatment during parthenogenetic activation of oocytes on the ER stress generation, apoptosis, and in vitro development of parthenogenetic porcine embryos. Porcine in vitro matured oocytes were activated by 1) electric stimulus (E) or 2) $E+10{\mu}M$ Ca-ionophore (A23187) treatment (EC). Oocytes were then treated by ER stress inhibitors such as salubrinal (200 nM) and tauroursodeoxychloic acid (TUDCA, $100{\mu}M$) for 3 h prior to in vitro culture. Parthenogenetic embryos were sampled to analyze ER stress and apoptosis at the 1-cell and blastocyst stages. The x-box binding protein 1 (Xbp1) mRNA and ER stress-associated genes were analyzed by RT-PCR or RT-qPCR. Apoptotic gene expression was analyzed by RT-PCR. At the 1-cell stage, although no difference was observed in Xbp1 splicing among treatments, BiP transcription level in the E group was significantly reduced by salubrinal treatment, and GRP94 and ATF4 transcription levels in EC group were significantly reduced by all treatments (p<0.05) compared to control. In the EC group, both apoptotic genes were reduced by ER stress inhibitor treatments compared to control (p<0.05) except Caspase-3 gene by TUDCA treatment. These results suggest that the treatment of ER stress inhibitor during parthenogenetic activation can reduce ER stress, and thereby reduce apoptosis and promote in vitro development of porcine parthenogenetic embryos.

• 융합정보논문지
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• 제12권3호
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• pp.204-213
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• 2022

본 연구는 대학생들의 구강건강수준에 영향을 미칠 수 있는 스트레스와 턱관절 장애를 조사하고 구강건강 관련 삶의 질과의 관련성을 파악하기 위해 실시하였다. 자료조사는 2021년 6월 3부터 2021년 7월 8일까지 대전 일부지역의 대학생 227명을 대상으로 실시하였으며, 독립표본 t검정, one-way ANOVA, Pearson 상관분석, 다중회귀분석을 이용하여 분석하였다. 조사결과, 턱관절 장애는 모든 스트레스 하위요인과 양의 상관성을 보였으며, 구강건강관련 삶의 질은 모든 스트레스 하위요인 및 턱관절 장애와 음의 상관성을 보였다. 또한, 구강건강관련 삶의 질에는 턱관절 장애와 대인 스트레스 및 가치관 스트레스가 영향을 미치는 것으로 나타났다. 이상의 결과를 토대로 대학생들의 스트레스와 턱관절 장애를 예방하여 구강건강관련 삶의 질을 향상시키는 체계적인 방안 모색이 요구된다.