• 제목/요약/키워드: Collection Date

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Haplotyping and Evolutionary Studies on GBSSII Gene in Korean Rice Collection

  • May Htet Аung;Yong-Jin Park
    • Proceedings of the Korean Society of Crop Science Conference
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    • 한국작물학회 2022년도 추계학술대회
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    • pp.218-218
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    • 2022
  • Granules-bound starch synthase II (GBSSII), one of the isoforms of granule-bound starch synthase (GBSS), is responsible for amylose synthesis by expressing in non-storage tissues such as leaf, stem, root, and pericarp. Up to date, little is known about this gene functions and basic knowledge of heritable characteristics of this gene, GBSSII. We identified functional haplotypes and performed evolutionary analyses on the GBSSII using 374 rice accessions (320 Korean bred and 54 wild) based on the classified groups. A total of 14 haplotypes were found, and almost all haplotypes (13) were functional, carrying 19 non-synonymous SNPs in two exons (exons 1 and 2). The lowest nucleotide diversity was detected in Tropical japonica (0.00145), while the highest pi-value was in Aus (0.01081), illustrating the signal of this gene evolution. The highest Tajima's D value in Aus (1.6380) indicates GBSSII gene domestication signature under balancing selection, while the lowest Tajima's D value in Temperate japonica (-0.8243) highlights that they were under positive selection, which may be purified due to the excess of rare alleles. The highest genetic differentiation was observed between Tropical japonica and aroma (FST = 0.921928). In contrast, the highest interbreed level was detected in Aus-admixture (FST = -0.20157). The genetic relatedness between and or among the wild and cultivated subpopulations was revealed through PCA, population structure, and phylogenetic analyses.

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Epidemiological application of the cycle threshold value of RT-PCR for estimating infection period in cases of SARS-CoV-2

  • Soonjong Bae;Jong-Myon Bae
    • Journal of Medicine and Life Science
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    • 제20권3호
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    • pp.107-114
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    • 2023
  • Epidemiological control of coronavirus disease 2019 (COVID-19) is needed to estimate the infection period of confirmed cases and identify potential cases. The present study, targeting confirmed cases for which the time of COVID-19 symptom onset was disclosed, aimed to investigate the relationship between intervals (day) from symptom onset to testing the cycle threshold (CT) values of real-time reverse transcription-polymerase chain reaction. Of the COVID-19 confirmed cases, those for which the date of suspected symptom onset in the epidemiological investigation was specifically disclosed were included in this study. Interval was defined as the number of days from symptom onset (as disclosed by the patient) to specimen collection for testing. A locally weighted regression smoothing (LOWESS) curve was applied, with intervals as explanatory variables and CT values (CTR for RdRp gene and CTE for E gene) as outcome variables. After finding its non-linear relationship, a polynomial regression model was applied to estimate the 95% confidence interval values of CTR and CTE by interval. The application of LOWESS in 331 patients identified a U-shaped curve relationship between the CTR and CTE values according to the number of interval days, and both CTR and CTE satisfied the quadratic model for interval days. Active application of these results to epidemiological investigations would minimize the chance of failing to identify individuals who are in contact with COVID-19 confirmed cases, thereby reducing the potential transmission of the virus to local communities.

Analysis of Shipping and Logistics News Articles using Topic Modeling (토픽모델링을 활용한 해운물류 뉴스 분석)

  • Hee-Young Yoon;Il-Youp Kwak
    • Korea Trade Review
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    • 제46권4호
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    • pp.61-76
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    • 2021
  • This study focuses on three logistics-related news (Logistics Newspaper, Korea Shipping Gadget, and Korea Shipping Newspaper) in order to present changes in logistics issues, centering on Corona 19, which has recently had the greatest impact in the world. For data collection, two-year news articles in 2019 and 2020 (title, article, content, date, article classification, article URL) were collected through web crawling (using Python's BeautifulSoup, requests module) on the homepages of three representative logistics-related media companies. As for the data analysis methods, fundamental statistical analysis, Latent Dirichlet Allocation (LDA) for topic modeling, and Scattertext were performed. The analysis results were as follows. First, among the three news media related to logistics, the Korea Shipping Newspaper was carrying out the most active media activities. Second, through topic modeling with LDA, eight logistics-related topics were identified, and keywords and significant issues of each topic were presented. Third, the keywords were visually expressed through Scattertext. This is the first study to present changes in the logistics field, focusing on articles from representative logistics-related media in 2019 and 2020. In particular, 2019 and 2020 can be divided into before and after the outbreak of Corona 19, which has had a great impact not only on the logistics field but also on our lives as a whole. For future work, a multi-faceted approach is required, such as comparative studies of logistics issues between countries or presenting implications based on long-term time-series articles.

Effects of self-care intervention using a mobile instant messenger on hemodialysis patient's knowledge, self-efficacy, self-care behavior and physiological index

  • Yu Kyung Shin;Mi Young Kim
    • Journal of Korean Biological Nursing Science
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    • 제26권2호
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    • pp.123-135
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    • 2024
  • Purpose: The purpose of this study was to examine the effects of self-care intervention using a mobile instant messenger on hemodialysis patient's knowledge, self-efficacy, self-care behavior and physiological indices. Methods: A non-equivalent control group pretest-posttest design was used. The participants consisted of 38 patients who had a regular hemodialysis of Seoul National University Hospital. They were assigned to one of two groups; an experimental group (n = 19) that had self-care intervention for 8 weeks and a control groups (n = 19) that had routine hemodialysis treatment. The data collection was conducted from September 5, 2022 to October 29, 2022. The date were analyzed by Chi-square test, Independent t-test, and Fisher's exact test using SPSS Win 29 program. Results: There was a significant difference in self-efficacy (t = 3.42, p = .002) between experimental and control groups. There was no significant differences between the two groups in knowledge (t = 0.80, p = .428), self-care behavior (t = 0.09, p = .929), potassium (t = -0.82 p = .416), phosphorus (t = -0.03, p = .974), weight gain (t = 0.16, p = .867). Conclusion: Based on above results, it was verified that self-care intervention in this study was an effective indicator in improving the self-efficacy. There is a requirement to formulate comprehensive interventions capable of enhancing various indicators.

Clinical Nurses' Perception and Performance of Antimicrobial Stewardship (임상간호사의 항생제 스튜어드십 인식도와 수행도)

  • Noh, Bo Yeoung;Yu, Jungok
    • Journal of Korean Clinical Nursing Research
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    • 제30권2호
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    • pp.125-138
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    • 2024
  • Purpose: This study aimed to assess the perception and performance of antimicrobial stewardship among clinical nurses and to contribute to establishing their role through an Importance-Performance Analysis(IPA) matrix. Methods: The study included 203 nurses working in hospitals of general hospital level or higher. Data collection took place from April 9 to May 6, 2024. Data analysis involved descriptive statistics, t-tests, ANOVA, Scheffé tests, and IPA analysis. Results: The average perception score for antimicrobial stewardship was 4.42±0.46, while the performance score was 3.96±0.53. Significant differences in perception and performance were observed across several ares: observation of patients, checking with/suggesting to physician based on assessments, implement tests and antimicrobial administration, patient education and support, coordinating multiple disciplines and institutions, acquiring up to date knowledge(p<.050). Perception was highest in the area of implement tests and antimicrobial administration but lowest in coordinating multiple disciplines and institutions. Conclusion: To establish the specific role of nurses in antimicrobial stewardship, improving nurse perception and fostering collaboration with various experts are essential. Developing educational programs and institutional support tailored to nurses is necessary to address areas identified for improvement in both perception and performance.

Dynamic ontology construction algorithm from Wikipedia and its application toward real-time nation image analysis (국가이미지 분석을 위한 위키피디아 실시간 동적 온톨로지 구축 알고리즘 및 적용)

  • Lee, Youngwhan
    • Journal of the Korean Data and Information Science Society
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    • 제27권4호
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    • pp.979-991
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    • 2016
  • Measuring nation images was a challenging task when employing offline surveys was the only option. It was not only prohibitively expensive, but too much time-consuming and therefore unfitted to this rapidly changing world. Although demands for monitoring real-time nation images were ever-increasing, an affordable and reliable solution to measure nation images has not been available up to this date. The researcher in this study developed a semi-automatic ontology construction algorithm, named "double-crossing double keyword collection (or DCDKC)" to measure nation images from Wikipedia in real-time. The ontology, WikiOnto, can be used to reflect dynamic image changes. In this study, an instance of WikiOnto was constructed by applying the algorithm to the big-three exporting countries in East Asia, Korea, Japan, and China. Then, the numbers of page views for words in the instance of WikiOnto were counted. A collection of the counting for each country was compared to each other to inspect the possibility to use for dynamic nation images. As for the conclusion, the result shows how the images of the three countries have changed for the period the study was performed. It confirms that DCDKC can very well be used for a real-time nation-image monitoring system.

Developing the credit risk scoring model for overdue student direct loan (학자금 대출 연체의 신용위험 평점 모형 개발)

  • Han, Jun-Tae;Jeong, Jina
    • Journal of the Korean Data and Information Science Society
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    • 제27권5호
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    • pp.1293-1305
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    • 2016
  • In this paper, we develop debt collection predictive models for the person in arrears by utilizing the direct loan data of the Korea Student Aid Foundation. We suggest credit risk scorecards for overdue student direct loan using the developed 3 models. Model 1 is designed for 1 month overdue, Model 2 is designed for 2 months overdue, and Model 3 is designed for overdue over 2 months. Model 1 shows that the major influencing factors for the delinquency are overdue account, due data for payment, balance, household income. Model 2 shows that the major influencing factors for delinquency loan are days in arrears, balance, due date for payment, arrears. Model 3 shows that the major influencing factors for delinquency are the number of overdue in recent 3 months, due data for payment, overdue account, arrears. The debt collection predictive models and credit risk scorecards in this study will be the basis for segmented management service and the call & collection strategies for preventing delinquency.

A Study on the Improvement of the Collection Traps of the Pine Gall Midge (Thecodiplosis japonensis Uchida et Inouye) II. Effects of Temperature by the Treatment of the Collection Traps on the Fluctuation of Emergence (솔잎혹파리 발생예찰을 위한 우화기구 개발에 관한 연구 II. 우화기구별온도효과가 우화소장에 미치는 영향)

  • Oh M.H.;Woo K.S.;Shim J.W.
    • Korean journal of applied entomology
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    • 제18권3호
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    • pp.127-132
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    • 1979
  • This experiments were performed to investigate the temperature effects, which caused by the various types of collecting trap treatments, during the overwintering period of pine gall midge larvae, on the peak adult emergence time. And the following results were obtained. 1) The maximum temperatures inside of the collection traps were significantly different each other, and the vinyl cage showed the highest degree which highering $15^{\circ}C$, and standard cage, cage-50 and funnel trap highering $3-12^{\circ}C$ in monthly average comparing to control. 2) There was no significant difference among the treatment in minimum temperatures, during the overwintering periods of larvae. 9) The peak adult emergence time were May 15 in vinyl cage plot which shortened 20 days and both standard cage and cage-50 shortened 14 day than that of control. 4) The funnel type trap treatment delayed 6 days of the peak adult emergence comparing to control, in spite of the treatment showing higher maximum and cumulative temperatures than the control plot. 5) The decadal maximum temperatures of middle part of December and March were significantly correlated with the shortening of the peak adult emergence date.

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An Archaeological Review of the Inscribed Bricks Excavated from the Tomb of Jang Mui: A Focus on the Collection of the National Museum of Korea (장무이묘 출토 명문전(銘文塼)의 고고학적 검토 -국립중앙박물관 소장품을 중심으로)

  • Lee Nakyung
    • Bangmulgwan gwa yeongu (The National Museum of Korea Journal)
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    • 제1권
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    • pp.36-73
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    • 2024
  • The Tomb of Jang Mui located in Bongsan-gun, Hwanghae-do Province has attracted much attention since its first investigation due to the inscribed bricks found there that have allowed the guessing of the name and official title of its occupant and construction date. Inscriptions on these bricks, such as the "Prefect of Daebang Commandery Jang Mui" and the "Mu" (戊, the fifth sign of the Chinese calendar), and "Sin" (申, the ninth sign of the Chinese zodiac), have become the basis for believing the location of the government office of Daebang Commandery to be in Bongsangun, Hwanghae-do Province rather than somewhere in the Hangang River region. From the early days of its investigation, the tomb was suggested as historic remains of the Daebang Commandery along with the Earthen Fortress in Jitap-ri. Inscribed bricks excavated from the Tomb of Jang Mui were featured in several books and articles in the form of photographs and rubbings, leading to a vast body of studies on its construction period and the characteristics of its occupant that drew upon interpretations of the inscriptions. However, the inscribed bricks themselves were not publicly available outside those held in the collection of the University of Tokyo, making it difficult to expect consistent research findings on the types of inscribed bricks and their contents. Following previous studies re-examining the structure of the tomb and the materials used for its construction, most scholars dated the Tomb of Jang Mui to 348, a period after the collapse of Daebang Commandery. However, there is still a lack of adequate examination of the bricks, which account for the majority of the artifacts excavated from the tomb. Among the bricks excavated from most brick chamber tombs, including the Tomb of Jang Mui, only those with inscriptions or designs have been collected. Moreover, among these, only those with inscriptions or designs on the stretcher faces have been documented. Accordingly, the bricks themselves have been notably understudied. This paper intends to reorganize the contents of the inscriptions on eleven types (out of sixty-one pieces) of bricks in the collection of the National Museum of Korea, which make up the majority of the bricks excavated from the Tomb of Jang Mui. It also classified them according to their shapes. Furthermore, it examined the bricks from the Tomb of Jang Mui as architectural materials by focusing on their production techniques, including their forming, drying, and firing. Taking a more specific approach, it then compared the results to other bricks from the second century through the fourth century: those from the brick chamber tombs of the Nangnang and Daebang Commanderies and those from the brick chamber tombs built after Nangnang and Daebang Commanderies were ousted. The examination of bricks from the Tomb of Jang Mui has revealed that these bricks were basically produced using the brick manufacturing techniques of Nangnang, but they incorporated new elements found in bricks from brick chamber tombs or brick-and-stone chamber tombs constructed around the mid-fourth century in terms of their size, the use of lime, and the number of inscribed bricks. This supports the prevailing view that the date of the construction of the Tomb of Jang Mui is 348. The Tomb of Jang Mui sustained the existing brick chamber tomb burial tradition, but its ceiling was finished with stone. It demonstrates a blending of the brick chamber tomb practice of the Nangnang and Daebang Commanderies by using bricks produced based on related techniques, but with new elements such as the addition of a lime layer to the bricks. This fusion reflects the political circumstances of its time, such as the expulsion of the Daebang Commandery and the advance of the Goguryeo Kingdom, leading to diverse interpretations. Given archaeological evidence such as the structure, materials, and location of the tomb, the Tomb of Jang Mui appears to be highly related to the Goguryeo Kingdom. However, the forms of the inscribed bricks and the contents of the inscriptions share similarities with brick chamber tombs constructed during the third and fourth centuries in the Jiangsu and Zhejiang regions in China. Further studies on whether the use of lime was an influence from Goguryeo or a continuation of the Daebang tradition and a comparative examination with contemporaneous stone ceiling tombs will provide a more refined understanding of the Tomb of Jang Mui.

Investigation of False Positive Rates Newborn Screening using Tandem Mass Spectrometry (TMS) Technology in Single Center (단일기관에서 이중 질량 분석법(tandem mass spectrometry technology)을 이용한 선천성 대사이상 검사의 위양성율에 대한 연구)

  • Kim, Hyunsoo;Shin, Son Moon;Ko, Sun Young;Lee, Yeon Kyung;Park, Sung Won
    • Journal of The Korean Society of Inherited Metabolic disease
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    • 제16권1호
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    • pp.18-23
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    • 2016
  • Objective: Newborn screening leads to improved treatment and disease outcomes, but false-positive newborn screening results may impact include parental stress and anxiety, perception of child as unhealthy, parent-child relationship dysfunction, and increased infant hospitalizations. The purpose of this study was to investigate of the false positive rates and the causative factors of false positive results in Tandem Mass Spectrometry (TMS) in single center. Methods: Records were reviewed for all 18,872 subjects who were born in Cheill General Hospital, during January 1st, 2012 to December 31st, 2014. 17,292 neonates (91.62%) were tested for tandem mass screening almost in 2-5th day of life. Newborn babies whose first results were abnormal had been tested repeatedly by same methods in 7-14 day. If the results were abnormal again, further evaluation was performed. TMS analysis included data for the 43 disorders screened for using TMS broken down into three categories: fatty acid oxidation disorders, organic acidurias, and aminoacidopathies. The impact of several factors on increased false positive rates was analyzed using a multivariate analysis: time from birth to sample collection, birth weight, birth height, BMI, gender, gestational age, delivery type. Results: Males of the subjects were 8942 (51.7%), female 8350 (48.3%), the mean gestational age was $38.6{\pm}1.7$ weeks, the average birth weight $3,155.6{\pm}502.4g$, the average birth height $49.1{\pm}2.9cm$, and the average BMI $13.0{\pm}3.8(kg/m^2)$. Vaginal delivery cases were 9713 (56.2%), caesarean section 7,579 (43.8%). The average date of the inspection was $2.8{\pm}1.1$ days. 224 cases were identified as TMS positive. All the subjects were false positive (222/17,292, 1.30%) except 2 cases (1 male; benign phenylketonuria and 1 female; Short chain acyl-CoA dehydrogenase deficiency). The false positive rates were 0.61% in fatty acid oxidation disorders, 0.25% in organic acidurias, and 0.45% in aminoacidopathies. In our study, the date of inspection got late, the false positive rates got higher. Because almost the cases of late test date were in treatment in neonatal intensive care unit so their test date was affected by their medical conditions. False positive rate was higher in extreme immaturity${\leq}27$ weeks than newborns of gestational age >27 weeks [OR=6.957 (CI=1.273-38.008), p<0.025] and extremely low birth weight<1,000 g than newborns of birthweight ${\geq}1,000g$ [OR=5.616 (CI=1.134-27.820), p<0.035]. Conclusion: False positive rate of TMS was 1.30% in Cheil General Hospital. Lower gestational age and birth weight impacted on increased false positive rates. Better understanding of factors that influence the reporting of screening tests, and the ability to modify these important factors, may improve the screening process and reduce the need for retesting. of screening tests, and the ability to modify these important factors, may improve the screening process and reduce the need for retesting.

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