• 대한한의학회지
• /
• 제30권2호
• /
• pp.127-132
• /
• 2009

Objectives: This study aimed to investigate the stability of a decoction using three herbal plants and their major components according to the storage conditions and periods. Materials and Methods: A three-herb mixture (1:1:1) of Glycyrrhiza uralensis Fischer, Artemisia capillaris Thunberg, and Poncirus trifoliata Rafinesqui was decocted and kept at room temperature ($25{\pm}2^{\circ}C$) or cold temperature ($4^{\circ}C$) for 0, 2, 4 or 8 weeks in liquid form in a plastic pack under dark conditions. At time points given, they were lyophilized. 200 mg of powdered samples were dissolved in 1 mL of 90% methanol and then applied to a high performance thin layer chromatography (HPTLC) with glycyrrhizin, 6,7-dimethoxycoumarin or poncirin for quantitative or qualitative analysis. Results: There were no gross changes in HPTLC-based compositional band-patterns of the three herbal mixture according to the storage conditions and period. The major components of each herb, glycyrrhizin, 6,7-dimethoxycoumarin and poncirin, showed slight time-dependent reduction in their contents both at room and cold temperature for 8 weeks. Conclusion: We could conclude that the current herbal decoction is generally safe for the stability at both RT or CT for at least 8 weeks. Nevertheless, we proposed that further advanced studies are required for more multiple herbal mixtures and longer storage periods.

• 설비공학논문집
• /
• 제22권12호
• /
• pp.891-896
• /
• 2010

The objective of the present study is to reveal the effects of a phase-change material on the performance of a Kimchi refrigerator. Two-percent salt water, of which melting temperature was $-1.1^{\circ}C$, was used for the phase-change material. The salt water was packed in silicon cases and inserted between Kimchi container and the copper pipe of the evaporator. The maximum and minimum temperatures of the inner wall of the Kimchi container without salt-water pack were $-0.2^{\circ}C$ and $-8.9^{\circ}C$, which were remarkably improved by using the salt-water packs, resulting $-0.5^{\circ}C$ and$ -1.9^{\circ}C$. This shows a useful application of using phase-change materials for accurate temperature controls.

• 한국항해항만학회:학술대회논문집
• /
• 한국항해항만학회 1998년도 추계학술대회논문집:21세기에 대비한 지능형 통합항만관리
• /
• pp.223-238
• /
• 1998

In this study, to investigate the effect of process variables such as reduction in area, semi-die angle and the rectangular ratio to the corner filling which influences the dimensional accuracy of the final product in the drawing of the cluadrangle rod from a round bar, it has been simulated by three dimensional rigid-plastic finite element method. In order to reduce the number of simulation artificial neural network has been introduced. Also, through the experimental investigation, the present results have been implemented on the industrial product. In results, the main process variable is the combination of the semi-die angle in case of the irregular shaped drawing process and reduction in area in the event of regular shaped drawing process, respectively.

• 대한핵의학회지
• /
• 제38권1호
• /
• pp.21-29
• /
• 2004

목적: 젊은 흡연자 및 비흡연자에서 찬물자극 후 심근혈류 예비능을 $H_2^{15}O\;PET$을 이용하여 측정한 후 비교함으로써 흡연에 의한 관상동맥 내피세포의 기능저하를 평가하고자 하였다. 대상 및 방법: 젊은 흡연자 9명($23.8{\pm}1.1$세; $6.6{\pm}2.5$ pack-years) 및 비흡연자 9명($23.8{\pm}2.9$세)에 대하여 안정상태 및 찬물자극 후, 그리고 아데노신 주입 중에 $H_2^{15}O$를 순간주사하고 동적 PET영상을 획득한 뒤, NMF 방법으로 입력 방사능곡선 및 조직 방사능곡선을 처리하여 심근혈류량을 산출하였다. 결과: 흡연자군 및 비흡연자군 사이에 심박수혈압곱 및 안정시 혈류량에는 유의한 차이가 없었다. 그러나, 찬물자극 자극 후에는 심근혈류가 흡연자군에서 비흡연자군에 비하여 유의하게 낮았으며(흡연자군 심근혈류 : $1.25{\pm}0.34$ ml/g/min, 비흡연자군 심근혈류=$1.59{\pm}0.29$ ml/g/min ; p=0.019), 특히 안정시 심근혈류에 대한 찬물자극 후의 심근혈류의 비(내피세포 기능에 의한 심근혈류의 예비능)도 흡연자에서 유의하게 낮았다(흡연자군=$90{\pm}24%$, 비흡연자군=$122{\pm}28%$ ; p=0.024). 한편, 아데노신 주입시의 심근혈류는 두군 간에 유의한 차이가 관찰되지 않았다(흡연자군 심근혈류=$5.81{\pm}1.99$ ml/g/min, 비흡연자군 심근혈류=$5.11{\pm}1.31$ ml/g/min ; p=NS). 결론: 젊은 흡연자에서 찬물자극 후에 $H_2^{15}O\;PET$을 이용하여 측정하여 산출한 심근혈류의 예비능이 젊은 비흡연자에 비하여 감소되어 있어서 흡연에 의한 관상동맥 내피세포의 기능장애를 확인할 수 있었다.

• Journal of Dairy Science and Biotechnology
• /
• 제24권1호
• /
• pp.9-18
• /
• 2006

국내산 UHT-ESL우유와 UHT 처리우유 총 150 packs을 냉장온도 (7$^{\circ}$C)와 실온 (20$^{\circ}$C)에서 5주간 저장하면서 1주마다 5 packs씩 시료로 취하여 미생물 함유 우유 packs의 발생시기, 발생 수와 미생물 종류별 함유 수준 등을 조사하였으며, 살균 후 2차 오염미생물로서 salmonella spp.와 staphylococcus aureus 존재 여부를 확인하였다. 총균수는 무균포장 공정을 실시하지 않은 UHT 처리우유가 UHT-ESL 우유보다 출현시기가 빠르고, 미생물 함유수가 많아 미생물학적 품질이 약간 낮은 것으로 나타났다. 그러나 두 제품군 모두 대장균군은 출현하지 않았으며, 호기성 포자형성균은 UHT 처리우유 2 제품에서 각각 7일 및 14일 만에 포자가 발아한 우유 pack이 1 pack씩 나타났으며, 7$^{\circ}$C에서 저장한 우유보다20$^{\circ}$C에서 저장한 우유에서 포자가 발아한 우유 pack의 수가 많았다. 내열성균은 2 제품군 모두 130$^{\circ}$C 이상의 열처리로 인하여 14일까지 출현하지 않았으나, 20$^{\circ}$C에서 저장한 우유는 21일 후(<300${\sim}$<3,000 CFU/ml), 7$^{\circ}$C에서 저장한 우유는 28일 후(40${\sim}$3,600 CFU/ml)에는 모든 pack에서 나타나기 시작하였다. 내냉성균은 UHT-ESL우유는 28일부터 측정되었으나, 한 제품의 UHT 처리우유는 7일 후부터 7$^{\circ}$C에서는 3,900${\sim}$102,000 CFU/ml까지, 20$^{\circ}$C에서 는 7일부터 28일까지 <3,000 CFU/ml 이하의 균수가 측정되었으며, 다른 제품의 UHT 처리우유는 21일에 30,000 CFU/ml 이하, 28일부터는 대부분의 pack에서 30,000 CFU/ml 이하로 발견되었다. salmonella spp.와 staphylococcus aureus에 의한 2차 오염은 모든 제 품에서 없었던 것으로 나타났다. 이러한 결과는 UHT 우유의 열처리 방법 및 포장방법에 따라서 냉장보관 우유의 유통기한을 3주간(21일)으로 설정하는 것이 가능한 것으로 나타났다.

• The Journal of Korean Physical Therapy
• /
• 제13권1호
• /
• pp.175-188
• /
• 2001

The purpose of this study was to investigate the effect of the cold air application for release of inflamation and pain in patient with acute rheumatoid arthritis who had taken medication(NSAIDs, DMARDs, corticosteroids). The participants had knee joint pain and ESR score over the 30. They were randomly assigned to three groups with each 15. Control group(group I ) were applied cold air and medication, experimental group II were applied hot pack and medication. and experimental group III were applied only medication. They were evaluated from April 1, 2000 to september 1,2000 ,and it was examined by ESR and VAS(visual analoge scale) in Lee Bang Hoon rehabilitation medicine clinic in Jeju Korea. The result of this study were as follow: 1. It was found that group 1, group II and group III had the statistically significant reduction of the ESR score according to treatment time(p<.05). 2. There were not statistically significant differences in ESR change pattern of each group according to treatment time(p>.05). 3. There were not statistically significant differences in the change of ESR according to treatment time between group I and group II , group I and group III , and group II and group III (p<.05). 4. It was found that group I . group II and group III had the statistically significant reduction of the VAS(Visual Analoge Scale) score according to treatment time(p<.05). 5. There were statistically significant differences in VAS score according to treatment time between control group(group I ) and experimental groups(group II and group III)(p<.05), but there were not stsiistically significant differences between experimental groups(p>.05).

• 혜화의학회지
• /
• 제9권1호
• /
• pp.319-335
• /
• 2000

According to the literatual study on the external medical trearment of Menorrhalgia and Leucorrhea for gynecologic condition, the results were as follows. 1. Using external medical treatment for Menorrhalgia is to insert vagina theraphy, fumigation theraphy, to wash vagina theraphy, to insert anus theraphy, to apply hot pack theraphy and use with suppository such as BANSUKHWAN(礬石丸), SASANGZASAN(蛇床子散), KUMBONGHYUNGJU(金鳳衡珠) 2. Using external medical treatment for Leucorrhea is washing and fumigation on vagina, to wash vagina, to insert vagina, cleansing theraphy and use with Suppository such as YONGYEOMGO(龍鹽膏), KAMISASANGJASAN(加味蛇床子散), SASANGSACHUNGSEJE(蛇床子洗劑). 3. ANGELICAE GIGANTIS RADIX (當歸) is in mostly general use for external medical treatment of Menorrhalgia and Leucorrhea, in that order ANSU SEMEN(杏仁), EVODIAE FRUCTUS(吳茱萸), TORILIS FRUCTUS (蛇床子), CORYDALIS TUBER(玄胡索), CINIAMOMI CORTEX(肉桂), CARYOPHYLLI FLOS(丁香), ALUMEN(枯白礬), AQUILARIAE LIGNUM (沈香). 4. The efficacy of medicines to use external medical treatment is as follow to help circulation of blood, to warm spleen and stomach, to warm blood, to warm uterus and remove cold, to remove heat and dry moisture, to down heat-product, to contract bloodvessel, to counteract poison and destory virus, to make energy and blood. 5. KUMBONGHYUNGJU, made same size as cherry and shape vagina medicine, use for Menorrhalgia, menstural irregularity, Leucorrhea, it has the efficacy as follow to remove cold and dry moisture, to warm uterus, to help circulation and romove pain, to down moisture-heat.

• 한국세라믹학회지
• /
• 제55권2호
• /
• pp.116-125
• /
• 2018

Color shade variation was investigated in zirconia dental blocks, prepared using commercial powders. As a reference color-shade block we used the color indexes of A2, A3.5, A4 and B3, according to the VITA classical color scale. The zirconia powders for color shade blocks showed colors of white, yellow, pink and grey, respectively, after firing at $1530^{\circ}C$. The zirconia powders were mixed according to the recipe of color shade blocks and shaped at lower pressure using a uniaxial hydrostatic press. The shaped sample was inserted into a vinyl pack and sealed in a vacuum form machine. The shaped block samples were reshaped at 450 bar using an isostatic cold press and fired at $1530^{\circ}C$ for three hours. In order to investigate the atmospheric color variation with firing temperature, the A2, A3.5, A4 and B3 sintered blocks were fired between $700^{\circ}C$ and $1300^{\circ}C$ under controlled atmosphere of $pN_2$ and $pO_2$. The surface color picture was taken using a smart phone camera and compared with the results obtained using the VITA classical color scale. Quantitative color index value, CIELAB, was measured using a color-meter. Above $800^{\circ}C$, the color darkness greatly increased with the increase of the reduction temperature and keeping time.

• Journal of Oral Medicine and Pain
• /
• 제26권2호
• /
• pp.157-160
• /
• 2001

Facial nerve paralysis(or Bell's palsy) which commonly occurs unilaterally, gives rise to paralysis of facial expression muscle. This condition is classified into symptomatic facial nerve paralysis due to intracranial tumor, post operative trauma, etc. and idiopathic facial nerve paralysis. To explain the etiology of idiopathic facial nerve paralysis, many hypothesis including ischemic theory, viral infection, exposure to cold, immune theory etc. were suggested, but there is no agreement at this point. The method to evaluate the facial nerve paralysis, when it occurs, consists of three stage scale method, image thechnics like CT and MRI, laboratory test to examine the antibody titers of viral infection, neurophysiologic test to evaluate the degree and prognosis of paralysis. Treatment includes medication, stellate ganglion block(SGB), surgery, physical therapy and other home care therapy. In medication, systemic steroids, vitamins, vasodilating-drug and ATP drugs were used. SGB was also used repeatedly to attempt the improvement of circulation and to stimulate the recovery of nerve function. Physical therapy including electric acupuncture stimulation therapy(EAST) and hot pack was used to prevent the muscle atrophy. When No response was showed to this conservative therapies, surgery was considered. After treating two patients complaining of Bell's palsy with medication(systemic steroids) and EAST, favorable result was obtained. so author report the case of facial nerve paralysis.

• 대한화상학회지
• /
• 제24권2호
• /
• pp.21-29
• /
• 2021

Purpose: Frostbite is a hazard to people exposed to cold environments. With the progression of modern industrial development and change of leisure behavior encountering cold environments, frequent accidental exposure to frostbite injury during work and human behavior is increasing, and the predisposing factors of frostbite were greatly changed than before. The purpose of this study was to make epidemiological analysis, and to review the treatment outcomes of frostbite. Methods: From March 2010 to February 2021, this study has included 27 patients with second- to third-degree frostbite injuries in Advanced Burn Reconstruction Center, Bundang Jesaeng Hosptial. A retrospective study was made about the distribution of age, gender, predisposing factors, prevalent area, type of managements, and the length of treatment period. Results: In our institution, acute management of frostbite patients has included rewarming, anticoagulation therapy (acetylsalicylic acid), and agents to improve vascular perfusion (lipo-prostaglandin E1 [Eglandin^®]). The 25 frostbite patients with second-degree frostbite (92.6%) were successfully managed by the conservative treatment alone with a mean of 20.3 days healing time. Two patients with third-degree frostbite (7.4%) also showed good outcomes after surgical reconstruction with a mean of 59 days healing time. In our clinical experiences of third-degree frostbite, definitive surgical reconstruction should be recommended to wait for more than 4~6 weeks for identification of clear demarcation of necrotic tissue caused by frostbite. In this study, 43 frostbite injuries site in 27 frostbite patients occurred. Among them, 15 patients (55.6%) had multiple-site frostbite injury. The most common predisposing cause of frostbite was refrigerant gas accidents (44.4%), followed by outdoor activity in cold environments (40.8%), misapplying ice pack for treatment purposes (7.4%), barefoot walking on the cold ground (3.7%), and loss of consciousness in cold grounds (3.7%). The most prevalent sites of frostbite injuries revealed as the hand (58.1%), followed by the foot (32.6%), face (7.0%), and abdomen (2.3%). And in the winter season from the November to March, the incidence rate of frostbite injuries was high at 74.1%. Conclusion: This study included 27 frostbite patients with 43 frostbite sites since last decade in a single institution at the community hospital. The frostbite patients with second-degree frostbite (92.6%) were successfully healed by the conservative treatment alone with a mean of 20.3 days healing time. The most common predisposing cause of frostbite was refrigerant gas accidents (44.4%), followed by outdoor activity in cold environments, etc. The most prevalent site of frostbite injuries was the hand (58.1%). And the most prevalent seasonal incidence of frostbite was from November to March (74.1%).