• 한국학교ㆍ지역보건교육학회지
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• 제24권4호
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• pp.27-37
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• 2023

Objectives: The purpose of this study was to investigate the effect of handgrip strength level on cognitive impairment in hypertensive patients. Methods: This study used the first to eighth year data of the Korean Longitudinal Study of Aging (KLoSA). Of the 10,254 respondents who participated in the basic survey, respondents were included that they were diagnosed with high blood pressure and had no cognitive impairment. The handgrip strength was based on the highest value of handgrip strength for both hands. Cognitive function using MMSE results and 23 points or less were defined as cognitive impairment. Cox models were conducted to estimate the hazard ratios (HRs) of cognitive impairment in relation to handgrip strength adjusting for covariates. Results: In the case of hypertension patients, the probability of cognitive decline decreased by 3.0% every time the maximum handgrip strength increased by 1 unit. In the analysis by age, under the age of 64 had a 1.8% decrease in the probability of cognitive decline whenever the maximum handgrip strength increased by 1 unit, and a 3.6% decrease in those over the age of 65. In the gender analysis, male had a 3.2% decrease in the probability of cognitive decline for every 1 unit increase in the maximum handgrip strength, and female had a 2.6% decrease. Conclusions: The results of this study are expected to be used as basic data for the development of interventions to prevent cognitive decline in hypertensive patients by identifying the effect of handgrip strength level on cognitive decline. It is also expected to be used as basic data for health education on the necessity of increasing muscle strength for hypertension patients in the community.

• 성인간호학회지
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• 제28권2호
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• pp.202-212
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• 2016

Purpose: The purpose of this study was to assess the relationship between cognitive function impairment and quality of life (QoL) among patients with breast cancer. Specifically, the intention was to verify the mediating effects for promoting behaviors leading to better health and QoL. Methods: A purposive sample of 152 patients undergoing chemotherapy was recruited. A cross-sectional survey design was used. Data were collected using four instruments: Everyday Cognition Scale, Korean Mini-Mental State Examination, Functional Assessment of Cancer Therapy-Breast Cancer Version 4, and Health Promoting Lifestyle Profile. Results: The mean score for subjective cognitive decline was 65.84; the health promotion behavior was 95.89, and 83.34 for QoL. Health promotion behavior was directly affected by cognitive decline ($R^2=6.0%$) as was QoL ($R^2=43%$). Subjective cognitive decline (${\beta}=-.57$ p<.001) and health promotion behavior (${\beta}=.37$, p<.001) were seen as predicting factors in QoL and explained 56% ($R^2=56%$). Health promotion behavior had a partial mediating effect in the relationship between self-reported cognitive decline and QoL (Sobel test: Z=-3.37, p<.001). Conclusion: Based on the findings of this study, nursing intervention programs focusing on managing cognitive decline and promoting health promotion behavior are highly recommended to improve QoL in cancer patients.

• 대한물리의학회지
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• 제15권4호
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• pp.67-74
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• 2020

PURPOSE: The progression of the center of pressure (COP) velocity of the stance phase may have important roles for predicting gait speed in older adults with cognitive decline. This study was conducted to identify the correlation between gait speed and the velocity of COP progression during the stance phase in older adults with cognitive decline. METHODS: Forty adults aged 65 years or older (twenty participants without cognitive decline, 20 participants with cognitive decline) were recruited. The COP progression velocity was measured using an F-scan pressure-sensitive insole system. The stance phase was divided into four sub-stages. (loading response, mid-stance, terminal stance, and pre-swing). Gait speed, double support phase, and cadence were also measured. Correlations and multiple regression analyses were performed. RESULTS: Gait speed was associated with the COP progression velocity in midstance (r = .719, p < .05), cadence (r = .719, p < .05) and the COP progression velocity in loading response velocity (r = .515, p < .05) in older adults with cognitive decline. However, no correlation was found in older adults without cognitive decline. In multiple regression analysis using gait speed as a dependent variable, the COP progression velocity in midstance and cadence were significant predictors of gait speed, with the COP progression velocity being the most significant predictor. CONCLUSION: The COP progression velocity is an important factor for predicting gait speed in older adults with cognitive decline, suggesting that the cognitive function influences gait speed and the velocity of COP progression.

• 한국보건간호학회지
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• 제31권2호
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• pp.209-219
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• 2017

Purpose: The purpose of this study was to identify the gender differences in the cognitive function and nutritional status among elderly people living in the community. Methods: This study used data from the 2014 National Survey on the Elderly and focused on 10,054 respondents who answered that they did not have dementia. The Korean version of Mini-Mental State Examination for Dementia Screening and the Nutrition Screening Initiative were used. IBM SPSS Statistics 23.0 was used to conduct statistical analyses. Results: The cognitive function score was 25.30 for men, which was higher than for women. The percentage of subjects who showed cognitive decline was 25.5% for males and 50.2% for females, which was statistically significant (p<.001). There were statistically significant differences in the nutritional status between males and females (p<.001). There was a statistically significant negative correlation between the cognitive function and nutritional status in both men and women (p<.001, p<.001). Conclusion: These results showed that the intervention to maintain cognitive functioning should be provided to elderly women with a low education level or high number of chronic diseases and medication, and an intervention to prevent the cognitive decline of the elderly should include nutritional management for health and function maintenance.

• 종양간호연구
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• 제12권1호
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• pp.1-11
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• 2012

Purpose: This study reviewed articles related to breast cancer, cognitive function and chemotherapy available in 4 databases. Methods: The researcher reviewed 32 pieces of literature that were published between January 2001 and November 2011. Results: Within the last decade, several studies have investigated whether adjuvant treatment of breast cancer affects cognitive function. A number of prospective studies have reported inconsistent results regarding whether chemotherapy affects cognitive function. Approximately half of the studies reported subtle cognitive decline in a wide range of domains among some breast cancer patients following chemotherapy, and others did not. Conclusion: Breast cancer patients receiving adjuvant chemotherapy showed the most deterioration and the most persistent decline in cognitive function. Since cognitive impairment is subtle, if evident at all, discrepant findings are due to hormonal, physiological, psychological or temporal confounding variables and differences in study design. Especially, that chemotherapy may impair memory, executive function, attention and visuospatial function in women with breast cancer.

• 한국식품과학회지
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• 제54권1호
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• pp.52-58
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• 2022

Phosphatidylserine (PS) is an essential component of the cerebral cortex and is associated with cognitive function. In this systematic review, the effects of PS on cognitive function in the elderly population are examined. The literature search included PubMed, EMBASE, Cochrane, and Web of Science databases. Subsequently, nine studies, including five randomized controlled trials and four pre-post studies, were selected. There were 961 participants in the selected studies; PS dosage varied from 100 to 300 mg/d, and the experimental period ranged from 6 weeks to 6 months. Five out of the nine selected studies were assessed to have a 'low' risk of bias, whereas the other four studies were assessed to have 'some concerns' regarding the risk of bias. The results of the meta-analysis concluded that PS had a positive effect on the memory of older adults with cognitive decline. Thus, PS appears to improve age-associated cognitive decline, especially memory, with no adverse effects.

• 디지털융복합연구
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• 제12권2호
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• pp.587-594
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• 2014

본 연구는 지역사회 노인의 인지기능 수준을 파악하고 인기기능저하에 영향하는 요인을 규명함으로써 인기기능을 유지 증진시키기 위한 프로그램을 개발하는데 도움이 될 기초자료를 제공하고자 실시되었다. J시의 65세 이상 노인 481명을 대상으로 2011년 9월 1일부터 9월 7일까지 구조화된 설문지를 이용하여 인구사회학적 특성, 건강관련 특성 및 우울에 대하여 조사하였다. 수집된 자료는 IBM SPSS Statistics V. 20을 사용하여 기술통계, Chi-square test, logistic regression analysis로 분석하였다. 본 연구 결과 대상자의 40.1%가 인지기능저하를 보였으며 인지기능저하와 관련된 요인은 교육수준(p<.001), 연령(p=.000), 우울 및 운동(p<.05)으로 나타났다. 그러므로 운동이나 우울에 대한 중재 프로그램을 집중적으로 시행할 필요가 있으며 특히 교육수준과 연령에 따른 개인차를 고려한 다양한 프로그램이나 교육이 마련되어야 할 것이다.

• 한국치위생학회지
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• 제22권5호
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• pp.333-340
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• 2022

Objectives: This study aimed to confirm the association between cognitive function and oral health status in the elderly. Methods: In this study, 5,794 respondents, aged 55 or older, who had participated in the 7th aging research panel survey were used. Statistical analyses were performed using a complex samples cross-tabulation analysis, complex samples general linear model, and a complex sample multinomial logistic regression analysis. Results: After analyzing the cognitive function of the elderly according to their oral health conditions, it was found that suspicions of dementia (19.6%) and cognitive function decline (25.9%) were more common for those who wore dentures than for those who did not wear dentures (p<0.001). Compared to those who did not wear dentures, those who wore dentures were linked to a 1.665 times higher suspicion of dementia (p<0.001). In comparison, cognitive decline was 0.964 times lower when the number of natural teeth increased by 1, and it was 0.941 times lower when the oral health evaluation index for the elderly increased by 1 point (p<0.001). Conclusions: As a result of this study, it was confirmed that cognitive function and oral health status are related in the elderly. Therefore, systematic measures for oral health management and oral health promotion should be prepared in tandem with awareness of possible cognitive decline in the elderly.

• 대한치매학회지
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• 제22권4호
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• pp.139-147
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• 2023

Background and Purpose: Dual walking task such as crossing over an obstacle may serve as an excellent tool for predicting early cognitive decline. Thus, this study aimed to investigate correlation between walking while crossing over an obstacle and executive functions under different gait phases to validate the use of walking with an obstacle for predicting early cognitive decline. Methods: A cross-sectional study was conducted on 48 elderly individuals from 2 day-care centers and 3 welfare-centers in Seoul and Gyeonggi, Korea. Executive function tests (Trail Making Test, Stroop test) and dual walking tests (gait speed, cadence, stance time, gait cycle time) were performed and compared using partial correlation analysis. Results: There were significant correlations between executive function and most of the gait variables (stance time, cadence, and gait cycle time) (p<0.05) when crossing over an obstacle while walking. Especially, stance time exhibited significant correlations with most executive functions (p<0.05). Conclusions: When evaluating executive function during walking with an obstacle, post-obstacle-crossing phase and stance time need to be observed.

• 대한간호학회지
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• 제46권1호
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• pp.19-28
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• 2016

Purpose: The purpose of this study was to test the mediating effect of psychological distress in the relationship between chemotherapy related cognitive impairment (CRCI) and quality of life (QOL) in people with cancer. Methods: A purposive sample of 130 patients undergoing chemotherapy was recruited for the cross-sectional survey design. Data were collected from November 2014 to June 2015. The instruments were K-MMSE (Korean Mini-Mental State Examination), Everyday Cognition (ECog), Hospital Anxiety Depression Scale (HADS), and Functional Assessment of Cancer Therapy-General (FACT-G). Data were analyzed using descriptive statistics, correlation, and multiple regression using Baron and Kenny steps for mediation. Results: The mean score for objective cognitive function was 27.95 and 69.32 for perceived cognitive decline. Overall quality of life was 91.74. The mean score was 17.52 for psychological distress. The prevalence was 56.2% for anxiety and 63.1% for depression, and 20.0% for CRCI. There were significant correlations among the variables, objective cognitive function and self-reported cognitive decline, psychological distress, and quality of life. Psychological distress was directly affected by CRCI. ($R^2=29%$). QOL was directly affected by CRCI. Psychological distress and CRCI effected QOL ($R^2=43%$). Psychological distress had a partial mediating effect (${\beta}=-.56$, p <.001) in the relationship between self-reported cognitive decline and quality of life (Sobel test: Z= -5.08, p <.001). Conclusion: Based on the findings of this study, nursing intervention programs focusing on managing cognitive decline, and decreasing psychological distress are highly recommended to improve quality of life in cancer patients.