• 한국노년학
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• v.41 no.2
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• pp.241-251
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• 2021

The purpose of this study was to investigate the structural relationship between the elderly's participation in exercise, cognitive function, and life satisfaction. The participants of this study consisted of 2491 elderly people who were the subjects of the 2017 elderly survey. The measuring tools were the cognitive function scale and the life satisfaction inventory. Participation in exercise used exercise time for one week. The collected data was analyzed through SPSS and AMOS 18 version. The results of this study were as follows. First, exercise participation was found to have a positive effect on the cognitive function of the elderly. Second, participation in exercise had significant effect on the life satisfaction of the elderly. Third, it was found that the cognitive function of the elderly had a positive effect on life satisfaction. Finally, it was found that cognitive function was as a mediator in the relationship between exercise participation and life satisfaction of the elderly. Various discussions on the structural relationship between the elderly's participation in exercise, cognitive function, and life satisfaction were presented.

• The Journal of Information Technology and Database
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• v.8 no.1
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• pp.41-65
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• 2001

This study proposes evaluation dimensions of object-oriented systems modelling tools and activities available in object-oriented systems development practices. The dimensions ale developed based on previous research in cognitive psychology, information systems modeling study, and object-oriented systems analysis arid design areas. The proposed dimension is composed of two dimensions. The one dimension includes abstraction levels of modelling and the other includes process and representation in modeling activities. Experts on object-oriented modeling were selected to evaluate the practical validity of the proposed dimensions and applications of major object-oriented modeling tools during systems development project. Most of the tools were observed to be used for representing objects rather than for modeling the process of related objects. The proposed modeling dimension will be evaluated for acquiring general validity in future empirical research.

• School Mathematics
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• v.15 no.1
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• pp.15-35
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• 2013

The purpose of the research is to categorize math learners into pattern through those tools that distinguish math learning style for middle school students. On the ground of survey for 976 middle school students, the fact that there are 16 different math learning style at the result of cluster analysis is confirmed and the results are compared and analyzed previous research. Also according to the each constituent of math learning style, dissimilarity of distribution about learner of different sexes and grades are analyzed. It's helpful to understanding the whole characteristics of learners regarding math learning to figure out their cognitive and affective learning styles through the tools to distinguish their math learning styles.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.9
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• pp.358-372
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• 2020

This study examined the effect of cognitive reserve on the cognitive function in adults. In addition, this study investigated the direct and indirect effects of factors, such as subjective memory decline, depression, and quality of life on the cognitive function. The participants consisted of 253 adults who were 40 to 80 years of age. The assessment tools included the cognitive function scale, depression scale, quality of life scale, subjective memory decline, and cognitive reserve scale. The data results were analyzed using SPSS 25.0, and PROCESS macro for SPSS Version 3.3 and bootstrapping were used. The results of multiple mediating of the cognitive reserve and cognitive function in adults did not have a mediating effect in depression and subjective memory decline, and the quality of life showed a complete mediating effect in the relationship between the cognitive reserve and subjective cognitive function. Based on the results of this study, adults must accumulate cognitive reserve continuously through various activities and continuous training so that the cognitive function can lead to a positive direction. Nevertheless, more studies on cognitive reserve and cognitive function in healthy adults are needed.

• Molecules and Cells
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• v.42 no.11
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• pp.739-746
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• 2019

Significant knowledge about the pathophysiology of Alzheimer's disease (AD) has been gained in the last century; however, the understanding of its causes of onset remains limited. Late-onset AD is observed in about 95% of patients, and APOE4-encoding apolipoprotein E4 (ApoE4) is strongly associated with these cases. As an apolipoprotein, the function of ApoE in brain cholesterol transport has been extensively studied and widely appreciated. Development of new technologies such as human-induced pluripotent stem cells (hiPSCs) and CRISPR-Cas9 genome editing tools have enabled us to develop human brain model systems in vitro and readily manipulate genomic information. In the context of these advances, recent studies provide strong evidence that abnormal cholesterol metabolism by ApoE4 could be linked to AD-associated pathology. In this review, we discuss novel discoveries in brain cholesterol dysregulation by ApoE4. We further elaborate cell type-specific roles in cholesterol regulation of four major brain cell types, neurons, astrocytes, microglia, and oligodendrocytes, and how its dysregulation can be linked to AD pathology.

• Journal of The Korean Society of Integrative Medicine
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• v.11 no.3
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• pp.49-57
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• 2023

Purpose : This study aimed to systematically review the correlation between hand dexterity and cognitive function in the elderly, and summarize various evaluation tests and results analysis methods for manual dexterity tests applied to this population. Methods : We searched published studies in the Korean Studies Information Service System and PubMed databases from January 2013 to March 2023. The main keywords used were "dexterity," "fine motor," "elderly," "cognitive function," and "correlation." A total of 10 studies were selected for analysis from the 1,524 searched articles. The included studies consisted of a cohort study, a longitudinal study, and eight cross-sectional studies which were analyzed for patients, intervention, comparison, and outcomes. Results : Analyzing the qualitative level of 10 studies, 8 articles (80%) were non-randomized two-group studies that provided level II evidence whereas the remaining 2 studies (20%) were non-randomized single-group studies (level III evidence). Therefore, these results indicated that the level of evidence in this field is generally high. The Purdue pegboard test was the most commonly used evaluation test for manual dexterity, and velocity speed was the most frequently employed analysis method. Results indicated that there were significant differences in manual dexterity test between the normal elderly, those with mild cognitive impairment, or dementia. Conclusions : These results can be used as a basis for selecting dexterity test evaluation items and methods to analyze it in the elderly while screening for cognitive impairment. In addition, this study highlights potential areas for future research on the development of manual dexterity evaluation tools and techniques for analysis and the need for more reliable and valid methods for assessing cognitive function in the elderly.

• Korean Journal of Cognitive Science
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• v.10 no.1
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• pp.57-66
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• 1999

We believe that science experiments in a laboratory are essential for science education. Scientific experiments begin with situations set by selecting and locating tools and reagents. and by proper experimental behavior, and thereafter situations are changed by natural laws and intermediate experimental behavior. While scientists and students do experiments, they build a cognitive model internally, do causal reasoning on the model to derive system behavior, and then learn scientific truth. We suggest not only a representation method for a 2-dimentional model and for ontological entities necessary in causal reasoning, but also an inferencing method to derive behavior. Chemistry experiments are chosen for the implementation. For the ontological entities, we consider experimental tools, reagents and their heirarchical structures, physics and chemistry natural laws, and functional abstraction knowledge. In order to show the usefulness of our methods, we have developed a program, called ACUArtificial Chemistry Laboratory), which provides an experiment environment where students can do non-predetermined experiments, and shows experiment려 system behavior similar to what happens in the same situation in a real world and descriptions about why it happens.

• Korean Journal of Biological Psychiatry
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• v.20 no.4
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• pp.119-128
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• 2013

Objectives Memory impairment is a very important mental health issue for elderly and adults. Mild cognitive impairment (MCI) is a prodromal stage of Alzheimer's disease (AD). Early detection of the prodromal stage of patients with AD is an important topic of interest for both mental health clinicians and policy makers. Methods Electroencephalograpgy (EEG) has been used as a possible biological marker for patients with MCI, and AD. In this review, we will summarize the clinical implications of EEG and ERP as a biological marker for AD and MCI. Results EEG power density, functional coupling, spectral coherence, synchronization, and connectivity were analyzed and proved their clinical efficacy in patients with the prodromal stage of AD. Serial studies on late event-related potentials (ERPs) were also conducted in MCI patients as well as healthy elders. Even though these EEG and ERP studies have some limitations for their design and method, their clinical implications are increasing rapidly. Conclusion EEG and ERP can be used as biological markers of AD and MCI. Also they can be used as useful tools for early detection of AD and MCI patients. They are useful and sensitive research tools for AD and MCI patients. However, some problems remain to be solved until they can be practical measures in clinical setting.

• Journal of Hospice and Palliative Care
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• v.16 no.3
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• pp.145-154
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• 2013

This study was performed to evaluate the existing pain assessment methods including the tools developed for use with nonverbal older adults with dementia, and to suggest recommendations to clinicians based on the evaluations. Computerized literature searches published after year 2000 using databases - Google scholar, RISS, KoreaMed, Medline, ScienceDirect, CINAHL - were done. Searching keywords were 'pain', 'pain assessment', and 'cognitive impairment/dementia'. The pain assessments for non-communicative dementia patients who are unable to self-report their pains are often made using the assessment tools relying on the observation of behavioral indicators or alternatively the strategy of surrogate reporting. While several tools in English version and only one in Korean are suggested for the pain assessments based on the observation of behavioral indicators, none are commonly used. In this review, we selectively evaluated those tools known to show relatively higher degree of validity and reliability for nonverbal older adults with dementia, namely, CNPI, DOLOPLUS 2, PACSLAC, PAINAD, and DS-DAT. It is hoped that the present review of selected tools for assessing pain in those vulnerable population and the general recommendations given be useful for clinicians in their palliative care practice. And future studies should focus on enriching the validation of the useful tools used to observe the nonverbal patient's behavioral indicators for pain in Korean.

• Journal of agricultural medicine and community health
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• v.37 no.3
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• pp.111-130
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• 2012

Objective: The purpose of this study was to identify and compare social capital measurement tools for the convenient use in public health studies. Method and result: This study examined and compared social capital tools developed individually by the World Bank, the OECD, the United States, United Kingdom, Canada, Australia, Ireland, and Korea. A comprehensive framework was constructed with six conceptual dimensions and sixteen indices. The six dimensions included Membership, Network, Trust, Information and communication, Social and civic participation, and Social cohesion and exclusion, which connoted the structural, cognitive, bonding, bridging, operative, and output elements. The indices of each tool were respectively matched to the indices of the comprehensive framework. The comprehensive tools were Integrated Questionnaire for the Measurement of Social Capital (SC-IQ) of the World Bank with 27 questions and the European Social Survey (ESS) of the OECD with 80 questions. Conclusion: The SC-IQ should be utilized in public health studies due to its simplicity yet comprehensiveness as a social capital tool. The ESS should also be considered as a comprehensive tool.