• Journal of Korean Academy of Nursing
• /
• v.46 no.3
• /
• pp.420-430
• /
• 2016

Purpose: The purpose of this study was to test a hypothetical model of chemotherapy-related cognitive impairment (CRCI) and depression in people with gastrointestinal cancer. Methods: A purposive sample of 198 patients undergoing chemotherapy was recruited from November 2014 to July 2015. The instruments were Everyday Cognition (ECog), Hospital Anxiety Depression Scale (HADS), Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F), and M. D. Anderson Symptom Inventory-Gastrointestinal Cancer Module. Data were analyzed using descriptive statistics, correlation, and path analysis. Results: CRCI was directly affected by cancer symptoms (${\beta}=.19$, p=.004) and fatigue (${\beta}=.56$, p<.001)($R^2=47.2%$). Depression was directly affected by fatigue (${\beta}=.48$, p<.001) and CRCI (${\beta}=.27$, p<.001). However, The impact of cancer symptoms on depression was confirmed through the mediating effect of CRCI. Conclusion: Results indicate that in patients with gastrointestinal cancer undergoing chemotherapy along with the direct physiologic effects (fatigue, symptoms) of cancer treatment may have altered cognitive function leading to depression.

• Journal of the Korea Society of Computer and Information
• /
• v.20 no.11
• /
• pp.127-133
• /
• 2015

In this paper, we propose that college counselors be more knowledgable of adult ADHD symptoms and develop better understandings of subtypes of the disorder. The findings in this study show that college students with different subtypes of ADHD symptoms experience different types of psychological maladjustment as well as different levels of psychological distress. Specifically, combined-type trait group show the highest levels of each of subscale of SCL-90-R among the other groups (i.e., normal, predominant inattentive subtype, hyperactive-impulsive type). Furthermore, combined typed trait group show significantly higher levels of animosity and paranoid ideation than the others. Therefore, college counselors need to provide effective interventions addressing intense emotion and cognitive distortion among college students with ADHD combined symptoms.

• Journal of Technologic Dentistry
• /
• v.17 no.1
• /
• pp.58-71
• /
• 1995

This study was carried out in order to examine demographic variables and personal and working conditions affecting to self-esteem, self-efficacy and work autonomy and mental health of the dental technicians. For this study, questionnaires composed of 50 items for the measurement of psychiatric symptom, work autonomy, self-esteem and self-efficacy index and 14 items related with demographic variables and personal and working conditions were distributed to 400 dental technicians and the 304 of them were statistically analyzed the results were as the following ; 1. Self-esteem and self- efficacy in dental technicians appeared to be interacted. 2. Score of self-efficacy index was higher in dental technicians of young age, or high or professional education than in otherwise dental technicians. 3. Score of self-efficacy index was higher in dental technicians of young age or professional education than in otherwise dental technicians. 4. All of self-esteem, self-efficacy and work autonomy in dental technicians affected directly their psychiatric symptom. 5. Promotion, and communication with fellows and senior workers of dental technicians affected directly their psychiatric symptom. 6. Each of anxiety, anger, depression and cognitive disturbance appeared to be interacted.

• Journal of Korean Biological Nursing Science
• /
• v.17 no.4
• /
• pp.306-314
• /
• 2015

Purpose: The purpose of this study was to evaluate symptoms, depression and quality of life in colorectal cancer patients who underwent stoma reversal, and to assess the factors related to their quality of life. Methods: A descriptive study was conducted on 125 colorectal cancer patients who underwent stoma reversal in a tertiary hospital in Korea. Data were collected using the Korean versions of the European Organization for Research and Treatment of Cancer-Quality of Life Core 30 and Colorectal Cancer Specific Questionnaire 38 (EORTC QLQ-C30 and CR38), and the Hospital Anxiety-Depression Scale. Data were analyzed using descriptive statistics, t-test, one-way ANOVA, Pearson's correlation, and multiple regression analyses. Results: Participants experienced sexual problems, difficulties in defecation, and nausea/vomiting. About twenty-two percent of the patients were depressed and the mean score for global quality of life was $64.40{\pm}19.43$. The multiple regression showed that social and cognitive functioning, depression, and the location of the anastomosis were the important factors that made contributions to the quality of life in colorectal patients with stoma reversal. Conclusion: Our results suggest that symptom management and emotional support should be incorporated into nursing interventions to improve the quality of life in colorectal patients with stoma reversal.

• Korean Journal of Biological Psychiatry
• /
• v.23 no.4
• /
• pp.199-204
• /
• 2016

Objectives Although forgetfulness is a common complaint among menopausal depressed women, there is still a debate about the relationship between memory impairment and menopause. The aim of this study is to examine whether menopause is related to cognitive decline among women with depressive disorders. We hypothesized that postmenopausal depressed women show generally poorer performance than premenopausal depressed women on various cognitive function tests. Methods With a retrospective chart review, we identified a total of 87 female patients (45 premenopausal patients and 42 postmenopausal patients) who were hospitalized with depressive disorders from 2000 to 2016. Demographic and clinical variables and cognitive test results were compared between two groups. Results Education year is longer in premenopausal group than postmenopausal group whereas clinical characteristics (illness duration, recurrence, and symptom severity) and mean Intelligence Quotient (IQ) were similar between two groups. The postmenopausal group took longer time for Bender-Gestalt Test (BGT) recall, Trail Making Test (TMT)-A, and TMT-B than the premenopausal group. After controlling for age and education, significant difference was remained for BGT recall (p = 0.029). Conclusions Postmenopausal state may be related with decline of visuospatial memory function, in particular, among depressed female patients. Other areas of cognitive function including complex attention, verbal memory, auditory memory, and working memory might be interpreted while considering age and education level.

• The Journal of Internal Korean Medicine
• /
• v.42 no.5
• /
• pp.833-845
• /
• 2021

Parkinson's syndrome is a degenerative brain disease that presents characteristic motor symptoms of tremor, rigidity, and gait disturbance. In addition to these motor symptoms, Parkinson's syndrome also presents non-motor symptoms (NMSs) such as sleep disturbance and cognitive decline. NMSs reduce patient's quality of life and psychosocial functioning and cause economic burden on the patient, so appropriate evaluation and treatment are required. Lewy body dementia is one of the several diseases belonging to Parkinson's syndrome. Its symptoms such as cognitive function, memory impairment, and hallucinations occur with Parkinsonism. Although drug therapy is being used with drug treatment to treat non-motor symptoms, it has limitations such as side effects, which stimulated interest in other complementary treatment methods such as oriental medicine treatment, dance, and yoga. The patient in this case complained of tremor in the right upper extremity, muscle hypertension and pain, and persistent vision, memory, and cognitive decline. The patient was diagnosed with probable Lewy body dementia. The patient was hospitalized for 4 months and received acupuncture and herbal medicines. After treatment, the patient's NMS scale scores decreased from 90 to 63, and the Unified Parkinson's Disease Rating Scale scores (summed I, II, and III) decreased from 17 points to 8 points. The Beck Depression Inventory score decreased from 22 points to 13 points. In addition, the patient's subjective evaluation revealed improvement. In this case, a patient diagnosed with probable Lewy body dementia who did not respond to the standard treatment and did not want to take medications showed improvement in not only motor symptoms but also NMSs after integrative Korean medicine treatment.

• Korean Journal of Psychosomatic Medicine
• /
• v.4 no.2
• /
• pp.262-268
• /
• 1996

It is important not only understanding the underlying psychodynamic mechanism of the somatization but also understanding the somatization as a process where biological and sociocultural factors are acting as maintaining and exaggerating the primary vague somatic symptoms. Recently, among mechanisms of the somatization biological and cognitive aspect became more important than psychodynamics. When the doctors see patients complain physical discomforts without organic foundation, they should give attention to the mechanism of symptom amplification, misinterpretation, individual cognitive characteristics and learned behavior. Psychiatric disorders which show somatic symptoms should be also evaluated. Autonomic dysfunctions linked with stress would give some clues of the mystery of the mind-body relationship.

• Korean Journal of Psychosomatic Medicine
• /
• v.29 no.1
• /
• pp.42-48
• /
• 2021

Objectives : Based on the fact that cognitive functions decline known as comorbid symptoms of depression can precede depression, this study seeks to observe the effects of depressive symptoms and anxiety symptoms on cognitive function in healthy subjects. Methods : To recruit 50 general populations to evaluate cognitive and clinical symptoms and to find out the effects of clinical symptoms on cognitive functions, Pearson correlation and multivariate regression were conducted. Correlation analysis of subdomain cognitive function was conducted for reliability analysis. Results : Trail making test-B that evaluates the execution function correlates with depressive symptoms (r=0.300, p=0.03) and age (r=0.323, p=0.02). Depressive symptoms (β=0.304, p=0.03) and age (β=0.335, p=0.01) were significantly related to Trail making test -B (Adjusted R²=0.148). Subjective cognitive tests correlates with anxiety symptoms (r=0.434, p=0.002). In the correlation between cognitive functional items, Subjective cognitive tests was found to be correlated with other test except Spotter. Conclusions : In this study, depressive symptoms contribute independently to executive functions in addition to demographic characteristics such as age and duration of education. Given that cognitive decline is a common long-term clinical outcome in depression, we expect active early intervention and evaluation of cognitive function to be helpful.

• Korean Journal of Biological Psychiatry
• /
• v.25 no.1
• /
• pp.1-8
• /
• 2018

Insomnia is a common sleep-related symptom which occurs in many populations, however, the neural mechanism underlying insomnia is not yet known. The hyperarousal model explains the neural mechanism of insomnia to some extent, and the frontal cortex dysfunction has been known to be related to primary insomnia. In this review, we discuss studies that applied resting state and/or task-related functional magnetic resonance imaging to demonstrate the deficits/dysfunctions of functional activation and network in primary insomnia. Empirical evidence of the hyperarousal model and proposed relation between the frontal cortex and other brain regions in primary insomnia are examined. Reviewing these studies could provide critical insights regarding the pathophysiology, brain network and cerebral activation in insomnia and the development of novel methodologies for the diagnosis and treatment of insomnia.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• v.23 no.1
• /
• pp.15-25
• /
• 2020

Prevalence of pediatric obesity has increased worldwide in the last 20 years. Obese children suffer not only physical complications but also mental health problems such as depression, attention deficit hyperactivity disorder (ADHD), and eating disorders, as well as psychosocial impairments, such as school adjustment problems, bullying, and low self-esteem. Recently, there have been some studies on the association of mental health problems and pediatric obesity. In the treatment of pediatric obesity, many previous studies suggest multidisciplinary treatment. However, cognitive behavioral therapy (CBT) has attracted attention because obese children are accompanied by body image distortion, emotion dysregulation, and difficulties in stimulus control. This review is a narrative summary of the recent studies on mental health problems and CBT in pediatric obesity. The relationship between depression/anxiety and pediatric obesity is still inconsistent but recent studies have revealed a bidirectional relation between depression and obesity. Additionally, some studies suggest that obese children may have eating disorder symptoms, like loss of control eating, and require therapeutic intervention for pediatric obesity treatment. Furthermore, impulsivity and inattention of ADHD symptom is thought to increase the risk of obesity. It has also been suggested that CBT can be very effective for mental health problems such as depression, impulsivity, and body image distortion, that may coexist with pediatric obesity, and use of multimedia and application can be useful in CBT.