Purpose: This study was done to identify effects of cognitive function and cancer coping on quality of life among women with breast cancer treated with antineoplastic agents. Methods: The study was correlational research and participants were 145 women with breast cancer who had received antineoplastic agents. Data were collected from October to November, 2015 via online replies. Cognitive function was measured with the Functional Assessment of Cancer Therapy-Cognitive Function Version-3 (FACT-Cog), cancer coping, with the Korean Cancer Coping Questionnaire (K-CCQ), and quality of life with the Functional Assessment of Cancer Therapy-Breast Version-4 (FACT-B). Data were analyzed using descriptive statistics, t-test, ANOVA, $Scheff{\acute{e}}$ test, ANCOVA, Bonferroni test, partial correlation coefficient, and hierarchical multiple regression with SPSS 21. Results: Cognitive functions, total individual coping, and interpersonal coping explained 42% of quality of life. Cognitive function (${\beta}=.35$, p<.001) was the best predictor of quality of life, followed by total individual coping (${\beta}=.34$, p<.001), and interpersonal coping (${\beta}=.26$, p<.001). Conclusion: Results indicate that cognitive function and cancer coping are meaningful factors for quality of life among breast cancer survivors. Therefore when developing intervention programs for these women, content on cognitive function and coping skills as well as coping resources should be included.
Purpose: This study aimed to investigate objectively measured physical activity (PA) in institutionalized older adults with mild cognitive impairment (MCI) and to elucidate the influence of autonomic nervous function, salivary cortisol, and PA on cognitive functions based on neurovisceral integration model. Methods: Overall cognitive function was evaluated using the mini-mental state examination (MMSE) and executive function was evaluated using semantic verbal fluency test and clock drawing test. Actigraph for PA, HRV and sAA for autonomous function, and the geriatric depression scale for depression were used. Saliva specimens were collected in the morning for sAA and cortisol. Results: Ninety-eight older adults from four regional geriatric hospitals participated in the study. They took 4,499 steps per day on average. They spent 753.93 minutes and 23.12 minutes on average in sedentary and moderate-to-vigorous activity, respectively. In the multiple regression analysis, lower salivary cortisol level (β = - .33, p = .041) and greater step counts (β = .37, p = .029) significantly improved MMSE score. Greater step count (β = .27, p = .016) also exerted a significant influence on verbal fluency, and greater sAA (β= .35, p = .026) was significantly associated with a better clock drawing test result. Conclusion: Salivary cortisol, sAA and physical activity were significantly associated with cognitive functions. To prevent older adults from developing dementia, strategies are needed to increase their overall PA amount by decreasing sedentary time and to decrease salivary cortisol for cognitive function, and to maintain their sympathetic nervous activity for executive function.
Journal of the Korean Society of Physical Medicine
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v.17
no.3
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pp.51-58
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2022
PURPOSE: This study aimed to evaluate the correlation between executive function and gait evaluations for the elderly, and validate the obstacle gait evaluation as a cognitive impairment test tool. METHODS: This study was a cross-sectional design. 79 people aged 65 years or older were selected as subjects. The Korean version of the Mini-Mental State Examination (MMSE-KC) to evaluate overall cognitive function and the Trail Making Test (TMT) A, B to measure executive function were performed. The 4-meter walking speed test and the walking speed test while crossing over an obstacle were carried out to evaluate gait. The Spearman's correlation was used to measure the correlation between cognition and gait speed. RESULTS: There was no significant correlation between the 4 m gait speed and executive function( TMT-A (p = .056), TMT-B (p = .115)). However, there was a significant correlation between the 4 m gait speed and MMSE-KC (r = .277, p < .05). There was also a significant correlation between walking speed while crossing over an obstacle and all tests (MMSE-KC (r = .382, p < .01). TMT-A (r = -.327, p < .01), TMT-B (r = -.283, p < .05)). CONCLUSION: It was found that the gait speed while crossing over an obstacle was correlated with all cognitive function tests. Therefore, we suggest the use of the gait speed test while crossing over an obstacle rather than the simple gait test to diagnose cognitive decline.
Journal of the Korea Academia-Industrial cooperation Society
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v.18
no.5
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pp.355-365
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2017
This study investigatedwhether occupational therapeutic craft activity improves cognitive function and hand function in patients with acute stroke, with the hope of providing clinically useful results for further studies. From March 2016 to November 2016, thirty acute patients with stroke at A general hospital and B rehabilitation hospital in Seoul and Gyeonggi-do, Korea were enrolled and randomly divided into two groups. One group was treated with occupational therapeutic craft activity,and the other general exercise. The subjects performed each activity for 30 minutestwice weekly, for four weeks. To test the effect of intervention, hand function was tested with the Box & Block Test and the Jebsen-Taylor Hand Function Test.Cognitive function measures were the NCSE and Trail-Making Test. Over the four weeks of treatment activities, in the occupational therapeutic craft activity group, hand function measures(p<.05) increased significantly,as did cognitive function measures(p<.05). This study shows that occupational therapeutic craft activity improves hand function and cognitive function effectively in patients with acute stroke. Occupational therapeutic craft activity programscan be based on this study to prepare intervention programs for further studies with acute stroke patients.
Journal of the Korean Society of Physical Medicine
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v.18
no.1
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pp.87-97
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2023
PURPOSE: The purpose of this study was to investigate the effect of multimodal intervention through VR (virtual reality)-based immersion program on the cognitive function and brain activity of patients with mild cognitive impairment. METHODS: The subjects of the study were 10 people in the experimental group who applied a complex intervention that performed cognitive tasks using the movement of the upper extremities through the VR program, and 10 people in the control group who received traditional occupational therapy. After the study intervention was applied 5 times a week, 30 minutes a day for a total of 8 weeks, LOTCA-G(Lowenstein Occupational Therapy Cognitive Assessment for Geriatric Population) and NIRSIT LITE were used to compare. RESULTS: Significant differences in cognitive function and brain activity were noted between the pre- test and post-test in the experimental group. Brain activity showed statistically significant differences in four channels of the working memory domain and one channel of the metacognitive domain (p < . 05). Comparative analysis of the difference between the two groups revealed statistically significant differences in cognitive function and brain activity. The brain activity showed statistically significant differences in three channels of the working memory domain and one channel of the metacognitive domain (p < .05). CONCLUSION: Through the results of this study, it was found that the complex intervention of performing cognitive tasks using upper extremity movements through the VR program had a positive effect on the cognitive function of patients with mild cognitive.
The purpose of this study was to test the effects of music therapy on cognitive function and depression in demented old adults. This study was made with one -group in a pre- and post-test design. The subjects were seven demented old adults over, sixty-five years and with mild to moderate cognitive impairment, residing at a nursing home. Music therapy was given by one researcher and one research assistant for thirty to forty minutes twice a week for 4 months. Music therapy was conducted with the subjects both listening and singing with a cassette player and a double-handed drum. In order to evaluate the effects of music, we measured the level of cognitive function and depression at the beginning and at the end of the music therapy session by means of an MMSE- K developed by Kwon and Park and the Depression Inventory developed by Chon. The Data were analyzed using descriptive statistics and a paired t - test analysis using a SPSS PC package. The results are as follows: 1) The subjects of the music therapy showed improvement in cognitive function. The MMSE-K score was significantly increased after music therapy. Especially, memory recall was very significantly. 2) The subjects of the music therapy showed a slight decrease in depression. However, there was no significant difference in the degree of depression between mean scores measured before and after music therapy. The results suggest that music therapy is effective in improving and maintaining cognitive function in demented old adults. And we suggest that long-term music therapy will be required to improve depression in demented old adults. These findings are encouraging the idea that music therapy may improve cognitive impairment.
Purpose: The purpose of this study was to explore the influence of cognitive function and depressive symptoms on instrumental activities of daily living (IADL) in addition to identify the factors associated with IADL in community-dwelling older adults. Methods: This was a descriptive study with cross-sectional design. Data were collected from July 2013 to June 2014. A total of 143 participants without dementia, depression and disability were enrolled in this study. Cognitive function was measured using Seoul verbal learning test (SVLT), digital span (forward/backward) and fist-edge-palm test. The Korean-IADL and Short Geriatric Depression Scale (S-GDS) were used. Data analysis was performed using descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient, and hierarchical regression. Results: Overall, a multiple regression model revealed that approximately 27.4% of total variability in IADL in the sample of community-dwelling older adults could be explained by the significant 12 variables in this model ($R^2=0.274$, F=5.467, p<.001). Age, having religion and cognitive function were the predictors of IADL in community-dwelling older adults. Conclusion: This study suggest that we need to monitor cognitive function in older to maintain the ability for IADL in older adults. Also, individualized program for improving older adults' IADL should be included in nursing intervention.
The purpose of this research is to test the relationship between ACLT(Allen Cognitive Level Test) and FIM(Functional Independence Measure), MMSE-K(Mini-Mental State Examination), and MFT(Manual Function Test). 38 elderly persons with stroke were recruited. Pearson Correlation Coefficients is used for correlation test. There is statistically significant correlation between ACLT and FIM, MMSE-K, and MFT(p<.05). This results identified the relationship between cognitive function and activities of daily living, indicated the usability of ACLT as a cognition assessment tool and the need of research for it's application in stroke patients.
Purpose: The purpose of this study was to examine the effects of a cognitive training program on neurocognitive task performance and activities of daily living (ADL) in patients who had a stroke. Methods: The research design for this study was a nonequivalent control group non-synchronized design. Patients were assigned to the experimental (n=21) or control group (n=21). The experimental group received a 4-week cognitive training program and usual care (i.e., rehabilitation service), while the control was received usual care only. Cognitive function was measured with a standardized neurocognitive test battery and ADL was assessed at baseline and one and two months after completion of the intervention. Repeated measures ANOVA was used to determine changes in cognitive function and ADL over 2 months. Results: The interaction of group and time was significant indicating that the experimental group showed improvement in attention, visuospatial function, verbal memory, and executive function compared to the control group which had a sustained or gradual decrease in test performance. A significant group by time interaction in instrumental ADL was also found between the experimental group with gradual improvement and the control group showing no noticeable change. Conclusion: Findings show that the cognitive training program developed in this study is beneficial in restoring cognitive function and improving ADL in patients following a stroke. Further study is needed to investigate the long-term relationship between cognitive training participation and cognitive improvement and effective functioning in daily living.
Journal of The Korean Society of Integrative Medicine
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v.11
no.3
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pp.49-57
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2023
Purpose : This study aimed to systematically review the correlation between hand dexterity and cognitive function in the elderly, and summarize various evaluation tests and results analysis methods for manual dexterity tests applied to this population. Methods : We searched published studies in the Korean Studies Information Service System and PubMed databases from January 2013 to March 2023. The main keywords used were "dexterity," "fine motor," "elderly," "cognitive function," and "correlation." A total of 10 studies were selected for analysis from the 1,524 searched articles. The included studies consisted of a cohort study, a longitudinal study, and eight cross-sectional studies which were analyzed for patients, intervention, comparison, and outcomes. Results : Analyzing the qualitative level of 10 studies, 8 articles (80%) were non-randomized two-group studies that provided level II evidence whereas the remaining 2 studies (20%) were non-randomized single-group studies (level III evidence). Therefore, these results indicated that the level of evidence in this field is generally high. The Purdue pegboard test was the most commonly used evaluation test for manual dexterity, and velocity speed was the most frequently employed analysis method. Results indicated that there were significant differences in manual dexterity test between the normal elderly, those with mild cognitive impairment, or dementia. Conclusions : These results can be used as a basis for selecting dexterity test evaluation items and methods to analyze it in the elderly while screening for cognitive impairment. In addition, this study highlights potential areas for future research on the development of manual dexterity evaluation tools and techniques for analysis and the need for more reliable and valid methods for assessing cognitive function in the elderly.
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