• 대한수의학회지
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• 제48권4호
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• pp.481-487
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• 2008

A 17-month-old intact male Cocker Spaniel was presented with primary complaints of severe ascites, exercise intolerance, and diarrhea. Diagnostic studies revealed tricuspid and pulmonic regurgitation on phonocardiogram, right ventricular enlargement on the electrocardiogram, typical right cardiac enlargement signs on the thoracic radiography and tricuspid valve malformation and marked enlargement of the right atrium and right ventricle on the echocardiography and tricuspid and pulmonary regurgitation on the color spectral echocardiography, suggesting tricuspid valve dysplasia and pulmonary hypertension. Using angiography and cardiac catheterization, pulmonary hypertension was ruled out. Further echocardiographic study revealed membranous valvular structures cranial to pulmonary annulus causing pulmonary regurgitation. Based on these findings on the diagnostic investigation, the case was diagnosed as tricuspid valve dysplasia complicated with pulmonic regurgitation. The dog was medically managed with furosemide, enalapril, nitroglycerine transdermal patch and pimobendan after the ascitic fluid removal.

• 대한수의학회지
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• 제55권3호
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• pp.213-214
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• 2015

A 12-year-old female Cocker Spaniel (7.5 kg of body weight) was presented for resection of a mammary gland tumor. During surgery, the heart rate was remarkably decreased due to a second-degree type I atrioventricular block. Atropine (0.05 mg/kg) was administered to increase the heart rate. Although the heart rate was elevated, atrial bigeminy occurred and persisted until the dog fully recovered from general anesthesia. These results highlight the possibility of atrial bigeminy caused by atropine administration during anesthesia.

• 대한수의학회지
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• 제48권3호
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• pp.363-367
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• 2008

A 4-year-old female Cocker spaniel was presented with respiratory distress and abdominal distension. Pleural effusion, ascites, hepatosplenomegaly, and superficial lymphadenopathy were observed and multicentric lymphoma was diagnosed by cytological examination. Immunophenotyping of lymph node and bone marrow using polymerase chain reaction for antigen receptor rearrangement identified a stage V lymphoma originating from T-cell. Despite of systemic chemotherapy using L-asparagenase, vincristine, cyclophoaphamide and prednisolone, neurologic deficits came out and progressed. Cerebrospinal fluid analysis revealed neoplastic lymphocytic pleocytosis indicating central nervous system involvement of lymphoma. The postmortem diagnosis was confirmed based on the histology and imunohistochemistry.

• 한국임상수의학회지
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• 제28권4호
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• pp.431-434
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• 2011

7년령의 중성화된 수컷 코커 스파니엘이 왼쪽복부종괴, 식욕부진, 체중감소로 경북대학교 부속동물병원에 내원하였다. 혈액학적, 생화학적 검사로 중증의 백혈구증가증, 경도의 저알부민혈증, GGT의 급격한 증가를 나타내었다. 방사선학적 검사시 왼쪽신장의 거대한 종괴가 관찰되었으며, 폐전이는 관찰되지 않았다. 조직병리학적 소견에서 종괴는 신장세포암종으로 확진되었다. 편측성 신장요관절제술을 실시하였다. 추시 결과 수술 6개월 후 환축이 폐사되었음을 확인 할 수 있었다.

• 한국수정란이식학회지
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• 제23권2호
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• pp.119-125
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• 2008

A 3-month-old American Cocker spaniel was presented at the Veterinary Teaching Hospital, Chungbuk National University, for examination of urinary tract after dissection of vaginal mass at local clinic before 10 days. Clinical examination of the affected bitch revealed a normal sized vulva in a normal anatomical position with a grossly enlarged clitoris, which contained an os clitoris. On examinations of the genital gland, there were testis, epididymis, ductus deferens and uterus. The histology of both gonads was primarily testis. Seminiferous tubules were divided into many parts by fibrous connective tissue. A small number of spermatogonia was present, but large numbers of Leydig's cells were existed. A normal female karyotype (78, XX) was detected in metaphase spreads obtained from cultured peripheral lymphocytes. Y chromosome specific sequences were not detected in genomic DNA by PCR. After 27 months, the os clitoris was larger than 3-month-old dog and os bone was more calcified than young age. Combining the results of cytogenetic, molecular genetic and histological examinations, the dog was diagnosed as a female hermaphrodite with Sry-negative XX sex reversal.

• 한국임상수의학회지
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• 제32권3호
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• pp.235-238
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• 2015

서울에서 개의 안과질환에 대한 역학적인 특징에 대해 2009년 1월부터 2013년 12월까지우성동물메디칼센터에 안과질환으로 내원한 초진환자들의 자료를 분석하였다. 총 1253두의 안과환자들이 초진 내원하였으며, 평균나이는 7.93년령 (SD, 4.06)이었다. 환자중에 Shih Tzu (29.4%)가 가장 많았으며, Maltese, Yorkshire Terrier, Cocker Spaniel, toy Poodle (P < 0.01)이 뒤를 따랐다. 눈에서 질병이 호발하는 곳은 수정체 관련 질환이 가장 많았으며 (28.3%), 안검질환, 망막질환, 비루관질환, 포도막질환, 유리체질환, 시신경계 질환이 그 뒤를 따랐다(P < 0.01). 수정체, 안검, 망막, 비루관, 포도막, 유리체, 시신경계 질환들은 주로 양측성 질환(P < 0.01)으로 발생하는 경향을 보였다. Shih Tzu에서는 각막질환이 가장 많이 발생하였으며, 수정체, 안검, 망막, 녹내장 질환이 그 뒤를 따랐다. Maltese에서는 수정체, 안검, 망막, 각막질환의 순으로 질병이 발생했다. Yorkshire Terrier, Cocker Spaniel, 그리고 toy Poodle 종은 수정체 질환이 가장 많았다(P < 0.01). 안과질환으로 병원에 내원하는 주된 환자들은 Shih Tzu, Maltese, Yorkshire Terrier등과 같은 소형견들이었고, 대부분 수정체 질환과 같은 품종소인이 있는 질환이 대부분이었다.

• 한국임상수의학회지
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• 제21권2호
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• pp.197-199
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• 2004

A 2-month-old intact female English Cocker Spaniel weighting 2.8 kg was presented with pollakiuria and urinary incontinence. On the inspection, moisture around the perineum and hindlegs was observed with a mild urine odor. No other abnormalities were detected on physical examination. Retrograde vaginourethrography revealed the urachal remnant. The vesicourachal diverticulum was surgically removed without complications.

• 한국임상수의학회:학술대회논문집
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• 한국임상수의학회 2009년도 춘계학술대회
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• pp.220-220
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• 2009

• 대한수의학회지
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• 제51권1호
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• pp.69-72
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• 2011

Eosinophilic granuloma is a common hypersensitive inflammatory skin disease in cats, and rare in dogs and horses. The skin biopsies of 5 years old female Cocker spaniel and 2 years old female mixed dog had the clinical signs of skin nodules with alopecia were submitted for diagnosis. Solitary skin nodules and papillary nodules were presented on the left external ear and back of Cocker spaniel and on the external ear of mixed dog, respectively. Histopathologically, epidermis of skin showed mild to severe hyperplasia with multifocal ulceration. Small to large irregular, brightly eosinophilic foci with degenerating eosinophils and homogeneous degenerated collagens were existed in the dermis of both ear and back skin. Typical 'flame figures', a mixture of degenerated collagen and degranulated eosinophils, were observed in both cases. Based on the histopathologic findings and special staining characters, 2 cases were diagnosed as canine eosinophilic granuloma. This is the first report for the eosinophilic granuloma of dogs in Korea.

• 한국임상수의학회지
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• 제29권3호
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• pp.247-249
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• 2012

8살된 코커스파니엘 수캐가 지속적인 혈뇨 때문에 강원대학교 대학병원에 진료의뢰 되었다. 진단검사상, 지속적인 혈뇨, 경미한 백혈구 증가증, 단백뇨 및 초음파상 불규칙한 모양의 코에코성 종괴가 관찰되었다. 종괴는 주변 방광조직으로부터 분리되어 있었고 결절 형태를 띠고 있었다. 조직검사상, 호산구를 주요 세포로 하는 염증세포 침윤과 출혈 및 상피비후 소견이 관찰되었다. 진단검사를 토대로 호산구성 폴립성 방광염으로 진단되었다. 환자에서 외과적으로 병소를 제거하였고 meloxicam과 amitriptyline을 이용하여 내과적으로 처치하였다. 치료는 성공적이였고 재발은 현재까지 되지 않고있다.