• Journal of the Korean Applied Science and Technology
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• v.37 no.4
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• pp.830-838
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• 2020

The present study aimed to evaluate the effect of radiation mutant Perilla frutescens var. crispa on bone metabolism and the inflammatory response in a monosodium iodoacetateinduced rat model of osteoarthritis. radiation mutant Perilla frutescens var. crispa was administered orally at doses of 25, 50 or 100 mg/kg/day for 2 weeks before direct injection of monosodium iodoacetate (3 mg/50 μl of 0.9% saline) into the intra-articular space of the rats' right knees. The rats subsequently received the same doses of oral radiation mutant Perilla frutescens var. crispa for another 4 weeks. It was evaluated that the treatment effects based on serum biomarkers, and morphological and histopathological analysis of the knee joints. Compared with those in control rats, the radiation mutant Perilla frutescens var. crispa treatments significantly reduced the serum levels of inflammation, bone metabolism markers (i.e., COX-2, LTB4, MMP-3, and COMP), and the amount of fibrous tissue. Otherwise, it was significantly increased the concentration of TIMP-1 and calcitonin. In addition, the radiation mutant Perilla frutescens var. crispa treatments effectively preserved the knee cartilage and synovial membrane. As a result, it indicates that radiation mutant Perilla frutescens var. crispa prevented and alleviated osteoarthritis symptoms. Thus, radiation mutant Perilla frutescens var. crispa can be used in food and drug material for the management of osteoarthritis.

• Applied Biological Chemistry
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• v.38 no.4
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• pp.359-363
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• 1995

New ten N-[1-(benzotriazol-1-yl)alkyl]aniline(4) derivatives were synthesized and the crystal structure of 4h was shown by X-ray crystallography and the absolute configuration has been assigned as S form. The molecule crystallizes in the monoclinic system, space group $P2_{1}/n$. And the molecules in the crystal are linked with each other through the hydrogen bond $(N_{11}-H_{11}{\cdots}N3)$ with distance $2.300(11){\AA}$ The fungicidal activity($pI_{50}$) in-vitro against Botrytis cineria (BC), Phytophthora casici (PC) and Sclerotium cepinorum (SC) were determined by the agar dilution method. The structure activity ralationships (SAR) between structure of 4 and the activity were studied using a physicochemical parameters of substituents and multiple regression technique. Among these compounds, only the bromo group substituent(4f) showed higher activity, which depend on the hydrophobic(${\pi}$) of substituents. The relative orders of the activity are SC>BC> and PC, respectively. This implies that the activity is affected by the hydrophobic(${\pi}$) nature of the Z group rather than the X group. Linear free energy relationships(LFER) on the fungicidal activity with substituents has been also discussed.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.7
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• pp.677-686
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• 2016

A thermal power plant is the first CFBC (Circulating Fluidized Bed Combustion) power plant consisting of 2 boilers-1 turbine. The optimal height of a stack needs to be approximately 156 meters in the case of this thermal power plant; however, the thermal power plant sites satisfy a function and reduce the construction cost by using mountains in the sites after cutting the ground and locating an integrated office and chimney at an altitude of 70 meters thereby lowering the height of the stack to 86 meters. In addition, the integrated office, which has a combined stack style with a unique design, is constructed by connecting with 2 stacks and disposing the office and an observatory in the space between them. Therefore, this study examined the design concept that fulfils the structural, functional, and aesthetic factors, harmoniously by joining the integrated office and the stack, which are disparate, and investigated special construction methods (Slip Form, Steel Inner Flue & Lift-up) through which heterogeneous architectures are structurally, functionally, and aesthetically constructed.

• Geophysics and Geophysical Exploration
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• v.16 no.4
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• pp.257-267
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• 2013

3-D ore modeling was performed to understand the configuration of ore bodies by integrated analysis of borehole and geophysical data in iron-mine area. Five representative indices of rocks were designated, which were obtained from geological survey and borehole. The five indices of rocks were geostatistically simulated by Sequential Indicator Simulation method to delineate boundary of the ore bodies. And Ordinary Kriging and Sequential Gaussian Simulation was applied to make secondary information using resistivity data from magnetotellurics and DC resistivity survey, and this information was used for simple kriging with local varying means, one of integrated kriging techniques. From the correlation analysis between each properties, it was found that high grade of ore is characterized by increased density, whereas the electrical resistivity decreases. With the integrated results of geophysical and borehole data, it was also found that the real configuration of ore body was similar to the modeled result and information about ore grade in 3-D space was obtained.

• Journal of Convergence for Information Technology
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• v.10 no.10
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• pp.1-8
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• 2020

The need for storage, management, and retrieval techniques for alternative data has emerged as technologies based on data generated from business activities conducted by enterprises have emerged as the key to business success in recent years. Existing big data platform systems must load a large amount of data generated in real time without delay to process unstructured data, which is an alternative data, and efficiently manage storage space by utilizing a deduplication system of different storages when redundant data occurs. In this paper, we propose a multi-layer distributed data deduplication process system using the similarity of the Cuckoo hashing filter technique considering the characteristics of big data. Similarity between virtual machines is applied as Cuckoo hash, individual storage nodes can improve performance with deduplication efficiency, and multi-layer Cuckoo filter is applied to reduce processing time. Experimental results show that the proposed method shortens the processing time by 8.9% and increases the deduplication rate by 10.3%.

• The Journal of the Petrological Society of Korea
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• v.18 no.4
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• pp.279-291
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• 2009

Radon is a natural radionuclide originated from radioactive decay of radium in rocks and soil. It is colorless, odorless and tasteless elements that mainly distributed as gaseous phase in soil pore space. The present study analyzed the characteristics of long-term radon variation in granitic residual soil at Mt. Guemjeong in Guemjeong-gu, Busan and determined the effects of atmospheric temperature, rainfall and soil temperature and moisture. Periodic measurements of radon concentrations in soil gas were conducted by applying two types of in-situ monitoring methods (chamber system and tubing system). Radon concentration in soil gas was highest in summer and lowest in winter. The variations in soil temperature and atmospheric temperature were most effective factors in the long-term radon variations and showed positive co-relations. The air circulation between soil air and atmosphere by the temperature difference between soil and atmosphere was analyzed a major cause of the variation. However, other factors such as atmospheric pressure, rainfall and soil moisture were analyzed relatively less effective.

• Journal of The Korean Association For Science Education
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• v.37 no.6
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• pp.1005-1014
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• 2017

Focusing on the role of the science museum as an institution to improve the scientific literacy of the public, this study investigated public perception and behavior about science museum to know how much science museums affect the public by using social media big data analysis. For this purpose, we extracted texts containing 'science museum' in Naver blogs and Twitter, analyzed them by using network, frequency, co-ocurrence, and semantics analysis and compared them with the results in English speaking countries. As a result, blogs were mainly concerned with science museum among parents who have young children, while in Twitter posts from many students who visited as a group appeared. Therefore, the Korean public used science museum mainly as a space for children's experience, and in this case, programs and exhibitions of science museums are perceived positively. On the other hand, students who visited as a group showed some negative emotions. The result of comparison with the cases of foreign countries in terms of the function of the third generation science museum such as communications with the science museum and the public and the participation of the public in science, the Korean public hardly mentioned the scientific contents, words related to communications such as 'argue', and curators or staff after visiting the science museum. In contrast to many verbs related to meaningful activities such as 'learn', 'participate', 'listen', 'read', 'ask', 'think' appeared in English, only a small number of verbs include 'ask' and 'thin' appeared in Korean. Therefore, science museum need to improve impression, communicating with public, and involving activity with impact and variety after visit.

• Journal of the Korean Institute of Landscape Architecture
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• v.33 no.4 s.111
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• pp.129-142
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• 2005

Korea's pet-related society has been fast growing without the base and preparations of socio-cultural animal welfare. For the most part, Korea's current public parks, in particular, have a space structure in which a lot of friction between the general public who are not fond of dogs and dog owners in public places has been happening unavoidably. A lot of countries that are taking a lead role in animal welfare have built dog parte that the general public and dogs can enjoy together. This research starts with the realization that the concept of 'dog park' needs to be introduced in Korea as more and more Koreans own dogs and other pets. This research aims to provide guidance for dog park planning by drawing a dog park planning model and to promote basics for co-existence of dogs and people in a park and set in place animal welfare early and raise the level of awareness. Total 7 types of dog put 56 planning items including dog zone, dog playground, and agility, and a selective matrix by which it is possible to select essential recommendatory optional items by each type of dog park were drawn in this research. Overall there were the highest needs in separated area for dogs in park. A dog park planning model is designed as follows. 1) To select a dog park type that was introduced. 2) To set up facilities applicable in common and planning items desired in advance by each type. 3) To zone dog park areas by the priority order of planning items that were introduced and to position necessary facilities. 4) To plan program that should be were introduced. A dog park was expected to take some positive roles such as providing opportunities to socialize dogs, activating social communities, more effective park management by participating local community members and so on.

• Journal of the Korean Institute of Landscape Architecture
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• v.40 no.4
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• pp.51-61
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• 2012

Kyong-Eui Railway used to be one of the major cross-country railways connecting Busan and Shineuiju. Being the central axis of logistics and transportation in Korea, it also signifies a symbolic meaning of the people's desire for the unification of divided Korean peninsula. A steam locomotive that had stopped in Jangdan Station was bombed out during the Korean War. The locomotive has been neglected and covered with rust in DMZ over a half century, and now is becoming a historic reminder of divided Korea. The initial design approach was based on the three main perspectives of the relocation plan of the steam locomotive in Jangdan Station which is designated as the registered cultural asset no. 78: historical significance, role of a monumental space, and influence on and from the local culture and tourism. Three design subjects were especially highlighted which would represent the identity of the cultural asset, the stream locomotive. First, a vertical watching deck was installed to provide various view points toward the locomotive while ensuring the security of visitors as well as the cultural asset. Second, the Dokgae bride area has good design potentials being on the railway. However, the site is too narrow. Thus, a new ramp and a stairway were placed responding to the existing topography so that the pedestrian environment could be secured last, to respect the local context where the locomotive was originally located, mulberry trees in the locomotive were transplanted as well. Flowering plants were planted around the display area for better ventilation to minimize the negative impact on the locomotive.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.16 no.5
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• pp.121-133
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• 2017

Since the mid 1990s, policies have been actively promoted to improve safety and pedestrian environment around the school such as the improvement of School zone. However, the prevention of accidents was not effective because it did not extend to the school road where the main transportation route for children's commuting takes place. In addition, due to the rapid increase of automobiles, trunk road traffic in the peak time bypasses the back roads, which threatens children's safety and the environment by invading the school area, which is the main living space of children. In this study, the characteristics of domestic children's traffic accidents were investigated and the problems were analyzed by conducting a field survey on Yeouido Secondary School in Seoul and Unjung Elementary School in Gyeonggi Province. In addition, Variable speed limit signs and Beacons were installed in the pedestrian road of comunity including School zone, and the effects of facilities on the speed of vehicles were analyzed. As a result of the analysis, the Variable speed limit sign showed a deceleration effect of about 8.3km/h, and the Beacon showed a phenomenon in which the traveling speed of 0.8km/h increased only slightly. In addition, the traffic violation rate of passenger cars, buses, and lorries decreased by about 3% as a result of investigating the number of traffic violation vehicles before and after installation.