• 제목/요약/키워드: Co-regulator

검색결과 191건 처리시간 0.024초

에너지 절감을 고려한 캠퍼스 마이크로그리드에서 선형 전압제어 방식의 AVR을 이용한 CVR의 적용 (Application of Conservation Voltage Reduction using Automatic Voltage Regulator of Linear Voltage Control in Campus Microgrid with Power Consumption Reduction)

  • 임일형;이명환;신용학
    • 전기학회논문지
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    • 제66권7호
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    • pp.1039-1046
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    • 2017
  • Campus microgrid is designed and built by considering not only power generation but also power consumption management as connected microgrid type because the main goal of the campus microgrid is to save power consumption costs. There are many functions to achieve the goal and they are mainly to use generation-based functions such as islanding operation for peak management and for emergency events. In power distribution operation, Conservation Voltage Reduction (CVR) is applied in order to reduce power consumption. The CVR is defined as a function for load consumption reduction by voltage reduction in order to reduce peak demands and energy consumption. However, application of CVR to microgrid is difficult because the microgrid cannot control a tap of transformer in a substation and the microgrid normally is not designed with phase modifying equipment like a step-voltage-regulator which can control voltage in power distribution system operation. In addition, an impact of the CVR is depended on load characteristics such as a normal load, a rated power, and synchronous motors. Therefore, this paper proposes an application of CVR using linear voltage control based AVR in campus microgrid with power consumption reduction considering characteristics of load and component in the microgrid. The proposed system can be applied to each buildings by a configuration of power distribution cables; and the application results and CVR factor are presented in this paper.

MLL5, a histone modifying enzyme, regulates androgen receptor activity in prostate cancer cells by recruiting co-regulators, HCF1 and SET1

  • Lee, Kyoung-Hwa;Kim, Byung-Chan;Jeong, Chang Wook;Ku, Ja Hyeon;Kim, Hyeon Hoe;Kwak, Cheol
    • BMB Reports
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    • 제53권12호
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    • pp.634-639
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    • 2020
  • In prostate cancer, the androgen receptor (AR) transcription factor is a major regulator of cell proliferation and metastasis. To identify new AR regulators, we focused on Mixed lineage leukemia 5 (MLL5), a histone-regulating enzyme, because significantly higher MLL5 expression was detected in prostate cancer tissues than in matching normal tissues. When we expressed shRNAs targeting MLL5 gene in prostate cancer cell line, the growth rate and AR activity were reduced compared to those in control cells, and migration ability of the knockdown cells was reduced significantly. To determine the molecular mechanisms of MLL5 on AR activity, we proved that AR physically interacted with MLL5 and other co-factors, including SET-1 and HCF-1, using an immunoprecipitation method. The chromatin immunoprecipitation analysis showed reduced binding of MLL5, co-factors, and AR enzymes to AR target gene promoters in MLL5 shRNA-expressing cells. Histone H3K4 methylation on the AR target gene promoters was reduced, and H3K9 methylation at the same site was increased in MLL5 knockdown cells. Finally, xenograft tumor formation revealed that reduction of MLL5 in prostate cancer cells retarded tumor growth. Our results thus demonstrate the important role of MLL5 as a new epigenetic regulator of AR in prostate cancer.

A Low COST SOFT-SWITCHED AC-TO-TC CONVERTER

  • 최주엽;목형수;김택용
    • 전력전자학회:학술대회논문집
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    • 전력전자학회 1997년도 전력전자학술대회 논문집
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    • pp.135-140
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    • 1997
  • A highly efficient single-phase/three-phase compatible ac-to-dc converter is proposed and analyzed, which includes three identical single-phase both soft-switched dc-to-dc converter with boost converter as a pre-regulator for input power factor correction (PFC). The proposed converter structure provides a cost reduction and easy implementation of compatibility between single-phase 220V and three-phase 220V/380V with their inputs in delta or wye connections.

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LAXATIVE AND SPASMOGENIC ACTIVITIES OF A HERBAL FORMULA

  • Ryu, Seung-Duk;Park, Chang-Shin;Hwang, Sung-Yeoun;Chung, Woon-Gye
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2002년도 Current Trends in Toxicological Sciences
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    • pp.116-116
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    • 2002
  • The spasmogenic activities and acute toxicity study of Yumijangquebo (YMJQB), a Korean herbal laxative formulation, were subjected to pharmacological evaluation. When tested in the contractile extent of guinea pig ileum, YMJQB displayed a spasmogenic effects in a concentration up to 0.05mg/ml and then decreased contractility of ileum; exhibiting the similar pattern with acetylcholine, a physiological regulator for peristaltic movement of the gut.(omitted)

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Establishment of Analytical Method for Residues of Ethychlozate, a Plant Growth Regulator, in Brown Rice, Mandarin, Pepper, Potato, and Soybean Using HPLC/FLD

  • Kim, Jae-Young;Lee, Jin Hwan;Lee, Sang-Mok;Chae, Young-Sik;Rhee, Gyu-Seek;Chang, Moon-Ik
    • 한국환경농학회지
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    • 제34권2호
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    • pp.111-119
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    • 2015
  • BACKGROUND: Ethychlozate (ECZ) is a plant growth regulator of synthetic auxin for agricultural commodities (ACs). Accurate and sensitive method to determine ECZ in diverse ACs on global official purpose is required to legal residue regulation. As the current official method is confined to the limited type of crops with poor validation, this study was conducted to improve and extend the ECZ method using high-performance liquid chromatography (HPLC) in all the registered crops with method verification. METHODS AND RESULTS: ECZ and its acidic metabolite (ECZA) were both extracted from acidified samples with acetone and briefly purified by dichloromethane partition. ECZ was hydrolyzed to form ECZA and the combined ECZA was finally purified by ion-associated partition including hexane-washing. The instrumental quantitation was performed using HPLC/ FLD under ion-suppression of ECZA with no interference by sample co-extractives. The average recoveries of intra- and inter-day experiment ranged from 82.0 to 105.2% and 81.7 to 102.8%, respectively. The repeatability and reproducibility for intra- and inter-day measurements expressed as a relative standard deviation was less than 8.7% and 7.4%, respectively. CONCLUSION: Established analytical method for ECZ residue in ACs was applicable to the nation-wide pesticide residues monitoring program with the acceptable level of sensitivity, repeatability and reproducibility.

An Inductance Voltage Vector Control Strategy and Stability Study Based on Proportional Resonant Regulators under the Stationary αβ Frame for PWM Converters

  • Sun, Qiang;Wei, Kexin;Gao, Chenghai;Wang, Shasha;Liang, Bin
    • Journal of Power Electronics
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    • 제16권3호
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    • pp.1110-1121
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    • 2016
  • The mathematical model of a three phase PWM converter under the stationary αβ reference frame is deduced and constructed based on a Proportional-Resonant (PR) regulator, which can replace trigonometric function calculation, Park transformation, real-time detection of a Phase Locked Loop and feed-forward decoupling with the proposed accurate calculation of the inductance voltage vector. To avoid the parallel resonance of the LCL topology, the active damping method of the proportional capacitor-current feedback is employed. As to current vector error elimination, an optimized PR controller of the inner current loop is proposed with the zero-pole matching (ZPM) and cancellation method to configure the regulator. The impacts on system's characteristics and stability margin caused by the PR controller and control parameter variations in the inner-current loop are analyzed, and the correlations among active damping feedback coefficient, sampling and transport delay, and system robustness have been established. An equivalent model of the inner current loop is studied via the pole-zero locus along with the pole placement method and frequency response characteristics. Then, the parameter values of the control system are chosen according to their decisive roles and performance indicators. Finally, simulation and experimental results obtained while adopting the proposed method illustrated its feasibility and effectiveness, and the inner current loop achieved zero static error tracking with a good dynamic response and steady-state performance.

Na/K-ATPase beta1-subunit associates with neuronal growth regulator 1 (NEGR1) to participate in intercellular interactions

  • Cheon, Yeongmi;Yoo, Ara;Seo, Hyunseok;Yun, Seo-Young;Lee, Hyeonhee;Lim, Heeji;Kim, Youngho;Che, Lihua;Lee, Soojin
    • BMB Reports
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    • 제54권3호
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    • pp.164-169
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    • 2021
  • Neuronal growth regulator 1 (NEGR1) is a GPI-anchored membrane protein that is involved in neural cell adhesion and communication. Multiple genome wide association studies have found that NEGR1 is a generic risk factor for multiple human diseases, including obesity, autism, and depression. Recently, we reported that Negr1-/- mice showed a highly increased fat mass and affective behavior. In the present study, we identified Na/K-ATPase, beta1-subunit (ATP1B1) as an NEGR1 binding partner by yeast two-hybrid screening. NEGR1 and ATP1B1 were found to form a relatively stable complex in cells, at least partially co-localizing in membrane lipid rafts. We found that NEGR1 binds with ATP1B1 at its C-terminus, away from the binding site for the alpha subunit, and may contribute to intercellular interactions. Collectively, we report ATP1B1 as a novel NEGR1-interacting protein, which may help deciphering molecular networks underlying NEGR1-associated human diseases.

AC Chopper 3전극 방식의 듀티비에 따른 $CO_2$ 레이저 출력 특성에 관한 연구 (A Study on the Output Characteristics of AC Chopper Duty-Ratio $CO_2$ Laser System using 3 Electrode-type and Ring Blower)

  • 박성준;정현주;김근용;이유수;김휘영;김희제
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2001년도 하계학술대회 논문집 C
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    • pp.1697-1699
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    • 2001
  • In this paper, the circuit of AC Choppers for $CO_2$ laser power supply are proposed and investigated. IGBT-controlled ac voltage regulators, operating at high frequency chopping mode. Chopping-to-supply duty ratio plays an important role in terms of laser output. Laser input energy is varied by controlling the leakage transformer used with the proposed system. This improved circuit employs a 3 electrode - type and Ring Blower. This improved circuit system has many advantages compared with the conventional SMPS such as simple design requirement, easy implementation, high reliability, low switching loss, and consequently high efficiency. As a result, the maximun output was 16W at duty-ratio of 92%, total gas mixture of $CO_2$ : $N_2$ : He = 1 : 9 : 15, total pressure of 15torr.

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