• Title/Summary/Keyword: Co-agent

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DW1350, a Newly Synthetic Anti-osteoporotic Agent: 1. DW-1350 Inhibited Bone Resorption and Promoted Bone Formation

  • Lee, Jin-Soo;Whang, Yun-Ha;Ahn, Seok-Hoon;PanSoo;Jin, Sang-Mi;Yi, Sun-Shin;Jung, Young-Ho;Suh, Hong-Suk;Ryu, Jei-Man
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.154.2-155
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    • 2003
  • Recently, we developed a new anti-osteoporotic agent, DW-1350, which not only inhibited osteoclast formation but also induced osteoblast differentiation through the in vitro randomized screening studies. We identified inhibitory activities of DW-1350 for each step of osteoclast differentiation, fusion and pit formation process in co-culture system with mouse bone marrow and primary osteoblasts. (omitted)

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Pwevaporation Separation of Aqueous Ethanol Solution Through Poly(vinyl alcohol) Membranes Crosslinked Poly(acrylic acid-co-maleic acid) (Poly(acrylic acid-co-maleic acid)로 가교된 Poly(vinyl alcohol)막을 이용한 에탄을 수용액의 투과증발분리 특성)

  • 남상용;성경수;천세원;임지원
    • Membrane Journal
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    • v.12 no.4
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    • pp.255-261
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    • 2002
  • Poly(vinyl alcohol) (PVA) membranes crosslinked with poly(acrylic acid-co-maleic anhydride) (PAM) as a polymeric crosslinking agent were prepared to investigate the pervaporation performance for the dehydration separation of aqueous ethanol solution. The characteristics of the resulting membranes crosslinked(x) were analysed by FT-IR and water swelling test. The water swelling decreased with increasing crosslinking agent content. The crosslinked PVA membranes with PAM showed lower water swelling than those of PVA membrane crosslinked with glutaraldehyde and modified PVA membrane. The swelling of water molecules in the crosslinked PVA membranes is more restricted by both chemical crosslinking between PVA and polymeric crosslinking agent chains and physical crosslinking by the entanglement between the PVA and polymeric crosslinking agent chains. For the pervaporation of aqueous ethanol solution through the crosslinked membrane, as the contents of crosslinking agent increased, the separation factor increased while the permeation flux decreased. The separation factor slightly decreased and permeation flux increased with increasing feed water content. As a result it could be considered that PVA-PAM membranes suppressed the plasticization effect even in the range of high water concentration in fled.

Fabrication of Magnesium Alloy Foam Through $TiH_2$ and $CaCO_3$ ($TiH_2$$CaCO_3$를 이용한 마그네슘 합금의 제조)

  • Seo, Chang-Hwan;Seong, Hwan-Goo;Yang, Dong-Hui;Park, Soo-Han;Hur, Bo-Young
    • Journal of Korea Foundry Society
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    • v.26 no.6
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    • pp.267-271
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    • 2006
  • Metal foam is a class of attractive materials, which exhibits unique combinations of physical, mechanical, thermal, electrical and acoustic properties. In particular, it is light and good at absorbing energy, which makes it attractive in automotive and aerospace applications weight is critical. In this paper, the Mg alloy foam was prepared by melt foaming method by addition of calcium as thickening agent, and $TiH_2$ or $CaCO_3$ powder as blowing agent. The macrostructural observation of foamed Mg showed that the pore structures of Mg alloy foam made by $CaCO_3$ as blowing agent were much better than that of foams made by $TiH_2$ as blowing agent. In addition, this paper showed the possible reason of fabrication magnesium alloy foam in proportion to blowing agent and the porosity range was about 40 to 76% as results value.

Study on the Removal of Fluorescent Whitening Agent by Pretreatment Ozone Oxidation for MBR Process Application (MBR 공정 적용을 위한 전처리 오존산화에 의한 형광증백제 제거 연구)

  • Choi, Jang-Seung;Ryu, Seung-Han;Shin, Dong-Hun;Lee, Jae-Hun;Lee, Soo-Chol;Kim, Sung-Gi;Ryu, Jae-Young;Shin, Won-Sik;Lee, Seul-Ki;Park, Min-Soo
    • Textile Coloration and Finishing
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    • v.29 no.1
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    • pp.11-17
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    • 2017
  • In this study, ozone oxidation experiment was carried out for the removal of fluorescent whitening agent which is widely used in textile dyeing and paper industry. The stilbene fluorescent whitening agent has been industrialized since the earliest, and the amount of current production is the highest. Due to the characteristics of the fluorescent whitening agent that can not be removed by conventional wastewater treatment methods, the fluorescent whitening agent in wastewater treatment has difficulty in using as recycled water in the process. Pre-treatment ozone oxidation experiment was conducted prior to the introduction of Membrane Bio Reactor(MBR) treatment process by converting biodegradable materials into biodegradable materials. The removal efficiencies of fluorescent whitening agents, a diaminostilbenedisulfonic acid derivative by ozone oxidation were evaluated by $UV_{254}$ Scan, $COD_{Mn}$, T-N and color using a synthetic wastewater sample ($COD_{Mn}=433.0mg/{\ell}$) and paper and paper mill wastewater ($COD_{Mn}=157.2mg/{\ell}$).

Highly CO2-soluble 5-Amido-8-hydroxyquinoline Chelating Agents for Extraction of Metals in Sc-CO2

  • Chang, Fei;Park, Seo-Hun;Kim, Hakwon
    • Bulletin of the Korean Chemical Society
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    • v.29 no.7
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    • pp.1327-1331
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    • 2008
  • Novel $CO_2$-soluble 8-hydroxyquinoline (8-HQ) chelating agents were synthesized and evaluated for solubility and metal ion extraction ability in supercritical $CO_2\;(Sc-CO_2)$. Among them, secondary amide-containing 8- HQ derivatives cannot be dispersed well into Sc-$CO_2$, but tertiary amide-containing derivatives can dissolve completely in Sc-$CO_2$ even at low CO2 pressures, perhaps owing to the predominant intermolecular interaction between the chelating agent and the $CO_2$ molecule. Based on 8-HQ chelating agent solubility data, we investigated the extraction of metal ions ($Co^{2+}$, $Cu^{2+}$, $Sr^{2+}$, $Cd^{2+}$, and $Zn^{2+}$) using two highly $CO_2$-soluble 8-HQ derivatives (4d, 4e) in Sc-$CO_2$. The extraction efficiency of tertiary amide-containing 8-HQ ligands, both fluorinated and non-fluorinated forms, was dramatically increased in the presence of diethyl amine (organic base). We suggest that diethyl amine could play an important synergistic role in the stronger metal binding ability of 8-HQ through an in situ deprotonation reaction in Sc-$CO_2$ medium.

DW1350, a Newly Synthetic Anti-osteoporotic Agent: 2. Effect on Ovariectomized Osteoporosis Rat Model, a Histomorphometrical Aspect

  • Lee, Jin-Soo;Ku, Sae-Kwang;Jung, Da-Hee;Jin, Youn-Goo;Park, Jae-Hoon;Yang, Hee-Bok;Jung, Yong-Ho;Ryu, Jei-Man
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.155.1-155.1
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    • 2003
  • In the present study, the effect of DW-1350, a newly synthesized anti-osteoporotic agent, was evaluated in ovariectomized Rat. Female SD Rat mice underwent bilateral ovariectomy for prevention study that test article was administered from 2 days after ovariectomy for 6 weeks, for therapeutic study it was conducted from 6 weeks after ovariectomy for three months. (omitted)

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Distributed CoAP Handover Using Distributed Mobility Agents in Internet-of-Things Networks

  • Choi, Sang-Il;Koh, Seok-Joo
    • Journal of information and communication convergence engineering
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    • v.15 no.1
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    • pp.37-42
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    • 2017
  • The constrained application protocol (CoAP) can be used for remotely controlling various sensor devices in Internet of Things (IoT) networks. In CoAP, to support the handover of a mobile sensor device, service discovery and message transmission needs to be repeated, although doing so would increase the handover delay significantly. To address this limitation of CoAP, a centralized CoAP scheme has been proposed. However, it tends to result in performance degradation for an inter-domain handover case. In this letter, we propose a distributed CoAP handover scheme to support the inter-domain handover. In the proposed scheme, a distributed mobility agent (DMA) is used for managing the location of mobile sensors in a domain and performing handover control operations with its neighboring DMAs in a distributed manner. A performance comparison reveals that the proposed scheme offers a performance improvement of up to 29.5% in terms of the handover delay.

Influence of Amine Base Dispersing Agent on Properties of Silica Filled Rubber Compounds (아민계 분산제가 실리카 고무배합물의 물성에 미치는 영향)

  • Park, Sung-Soo;Kil, Sang-Gyu;Jang, Byung-Man;Song, Ki-Chan;Kim, Su-Kyung
    • Polymer(Korea)
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    • v.25 no.4
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    • pp.503-511
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    • 2001
  • Present silica dispersing agents are based mainly on fatty acid derivatives of Zn, K and mixture of fatty acid and metallic soaps are used to increase activity. The viscosity of silica filled rubber is lowered by Zn-K soap type silica dispersing agent, thus fluidity of hydrocarbon chains and processibility is improved. Silica dispersing agent should not exert an influence on chracteristics of vulcanization. But scorch and curing time is shortened by Zn-K soap type silica dispersing agent. A newly developed silica dispersing agent, which is a nonmetal type agent, reduced the viscosity and hardness of silica compounding rubber, and the highly increased degree of dispersion of silica is caused by interaction of silica and rubber. Also it did not affect the curing characteristics and scorch stability of silica compounding rubber.

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A Study on Clean Agents for Halon Replacement in the Portable Extinguisher with CO2 as an Expellant Gas (이산화탄소를 가압원으로 하는 할론대체 소화기용 청정소화약제에 대한 연구)

  • Jeong, Keesin
    • Fire Science and Engineering
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    • v.33 no.3
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    • pp.51-55
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    • 2019
  • To prevent ozone depletion caused by CFCs, the replacement of Halon with clean agents has been developed in the fire protection field along with refrigerants, detergents, and foaming agents. The alternatives for Halon 1211 have been developed in the portable fire extinguisher area and HCFC-123 is used widely as a clean fire extinguishing agent. The type of expellant gas is important because their own vapor pressure is low. In this study, HCFC-123, HCFC-124, HFC-125, and Novec-1230 were selected as fire extinguishing agents and CO2, which is expected to improve the fire extinguishing ability, was chosen as the expellant gas. For each agent, experiments changing the agent and CO2 amount were carried out and HCFC-123 showed a good result, as expected. The extinguisher, HCFC-123 of 1.5 kg, showed the same ability to suppress a class A and B fire as the extinguisher, HCFC-123 of 2.5 kg, which is currently sold on the market. According to this result, the expellant gas has a subsidiary fire extinguish effect. This can reduce the amount of HCFC fire extinguishing agent, which is categorized in the phase-out alternatives, and is a more eco-friendly and economical fire extinguisher than the previous one. This study can also help solve the problems of CO2 fire extinguishers for class B and C fires, and can be used to extinguish electric and electron facilities fire, which contains large amounts of class A fire combustibles.

The Effect of the Mixture of Nonionic Surfactant and Bioactive Agent for Surfactant-enhanced Soil Flushing (SESF) of TCB Contaminated Soil

  • Lee, Dal-Heui;Cho, Heuy Nam;Chung, Sung-Lae
    • Journal of Soil and Groundwater Environment
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    • v.19 no.2
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    • pp.1-6
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    • 2014
  • The objective of this study was to find the effect of the mixture of the nonionic surfactant and bioactive agent that solubilizes trichlorobenzene (TCB) present as a contaminant for surfactant-enhanced soil flushing (SESF). Three different nonionic surfactants and two different bioactive agents were obtained from four companies. Separate funnel experiments and shaker table agitation / centrifugation experiments were used for the test. Based on the separate funnel experimental results, three suitable mixture agents (APG + OSE, Brij 35 + MOSE, T-Maz 60 + MOSE) were selected. In the shaker table agitation / centrifugation experiments, these three different mixture agents were reduced to one (T-Maz 60 +MOSE). The maximum removal (95%) of TCB was obtained using a mixture of the nonionic surfactant and bioactive agent. Therefore, the used test methods and results can be used for SESF.