• Title/Summary/Keyword: Co-60 ${\gamma}-radiation$

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Effect of ionizing radiation on cultured submandibular gland (SG) cells of mouse (전리 방사선 조사에 의한 마우스 배양 악하선 세포의 변화)

  • Lee, Song-Jae
    • The Journal of Korean Society for Radiation Therapy
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    • v.4 no.1
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    • pp.71-77
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    • 1990
  • The present study was undertaken to investigate effects of ionizing radiation on DNA synthesis and chromosomal abnormality in cultured submandibular gland(SG) cells. SG cells from C57BL/6N Crj mice were cultured in Dulbecco's modified Eagle's medium (DME) supplemented with $10\%$ fetal bovine serum, antibiotics and fungizone. The cultured SG cells were irradiated with graded doses of gamma ray ($^{60}Co$) at a dose rate of 58.4rad/min. The effect of irradiation of $^{60}Co$ on DNA synthesis in cultured cells was evaluated by measuring the incorporation of 3H-TdR. Using conventional chromosome techniques and Giemsa staining methods, chromosomal abnormalities in cultured SG cells, induced by irradiation of $^{60}Co$ werw examined. Cytological observations were carried out by a light microscope with high resolving power. The results obtained were as follows : 1. DNA synthesis of SG cells was quantitatively dependent on a radiation dose compare to control. 2. A polyploids and few chromosome-type break, such as single and double breaks, deltions and triradial figures were more predominantly in irradiated SG cells than in control. This increase of chromosomal abnormality was in the proposition to the irradiation doses.

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Construction of Semi-universal Wedge Filter and Clinical Application for Co-60 Teletherapy Unit (코발트60 원격치료기에 대한 Semiuniversal Wedge Filter의 제작과 임상응용)

  • Kim, Myung-Ho;Yun, Suk-Rok;Shin, Dong-Oh
    • The Journal of Korean Society for Radiation Therapy
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    • v.3 no.1
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    • pp.45-50
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    • 1989
  • Wedge filter are used in high energy radiation therapy to obtain uniform isodose lines at small volume tumor and irregular body surface. The aim of this study is not only to describe the method of construction and setting of semi-universal wedge filter for $^{60}Co$ radiation therapy but also to get the optimum treatment planning by clinical application of wedge filter.

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Activation Energy Measurement of the $^{60}Co$ $\gamma$-ray Irradiated Epoxy Resin ($^{60}Co$ $\gamma$-ray 조사에 따른 에폭시 수지의 활성화 에너지 측정)

  • Lee, Kyoung-Yong;Kim, Ki-Yup;Hwang, In-Ra;Choi, Yong-Sung
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2008.04c
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    • pp.75-79
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    • 2008
  • In this paper, we measured the activation energy of the Bisphenol A type Epoxy resin (DGEBA)-Jeffamine system according to an irradiation. We put the mixed solutions to the silicon mold after mixing both DGEBA(216g) and Jeffamine(93.9g), curing agent of amine system. The mixed solutions were cured in the atmosphere during 24hours after finishing the first curing during 4hours in the vacuum oven under $80^{\circ}C$. The mixed solutions were cured in the atmosphere during 24hours after finishing the second curing during 12hours in the vacuum oven under $60^{\circ}C$ again. Prepared samples were irradiated to the dose rate of 8kGy/hr with 500kGy, 700kGy, 1000kGy, 1500kGy, 2000kGy, 2500kGy. Experimental results indicated activation energy of the samples reduced as the irradiation dose increased because of the peroxides of the Epoxy created by the oxidation and the radiation.

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Mutation Spectrum of Manganese (II) Peroxidase Gene in the Pleurotus ostreatus Mutants Induced by Gamma Radiation

  • Chang, Hwa-Hyoung;Lee, Young-Keun;Kim, Jae-Sung;Lee, Ki-Sung;Cho, Kyu-Seong
    • Journal of Microbiology
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    • v.41 no.1
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    • pp.52-57
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    • 2003
  • The mutational spectra in the manganese (II) peroxidase gene (mnp) of the Pleurotus ostreatus mutants induced by gamma radiation (Co$\^$60/) give evidence to prove the effect of gamma radiation on the gene. mnp of each mutant was cloned, sequenced and analyzed. Among the 1941 base pairs of the sequenced region of the mnP genes of 4 mutants (PO-5,-6,-15 and -16), nine mutational hotspots on which the same base was mutated simultaneously were found, additionally 6 mutations were also found at different positions in the mnp gene. These mutation-spectra were predominantly A:T\longrightarrowG:C transitions (50.1%). By the analysis of putative amino acid sequences, PO-5 and PO-16 mutants have 3 and 1 mutated residues, respectively. Since the mutational spectra reported herein are specific to the mnp gene, we propose that the mutational hotspots for the gamma radiation could be in the gene(5) within cells.

Detection Properties of Irradiated Dried Seafoods Using PSL and ESR (PSL과 ESR 분석에 의한 건조수산물의 방사선 조사 여부 판별 특성 연구)

  • Song, Beom-Seok;Han, In-Jun;Yoon, Young-Min;Choi, Soo-Jeong;Kim, Jae-Kyung;Park, Jong-Heum;Jeong, Il-Yun;Lee, Ju-Woon;Kim, Byeong-Keun;Kim, Kyu-Heon;Kim, Jae-Hun
    • Journal of Radiation Industry
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    • v.6 no.2
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    • pp.119-123
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    • 2012
  • The detection properties of gamma-irradiated (0~10 kGy) dried seaweed, dried shrimp, and seasoned dried filefish were investigated by photo-stimulated luminescence (PSL) and electron spin resonance (ESR). PSL could be used as a detection method on irradiated dried seaweed and dried shrimp as they showed photon counts greater than 5,000 counts/60 s (positive) in the irradiated samples with doses above l kGy. However, PSL could not be applied to detect irradiated seasoned dried filefish, because gamma-irradiated sample at 10 kGy even yielded photon counts less than 700 counts/60 s (negative). The ESR spectroscopy for only dried shrimp revealed specific signals derived from free radicals captured in the shell of shrimp. As a result, it is considered that PSL or ESR methods for detection of gamma-irradiated dried shrimp and only PSL can be used to detect gamma-irradiated seaweed. Furthermore, it is considered that hydrocarbon analysis of seasoned dried filefish containing fat by GC/MS and Thermo Luminance (TL) analysis of dried seaweed should be studied for detection of irradiation.

A Methodology of Dual Gate MOSFET Dosimeter with Compensated Temperature Sensitivity

  • Lho, Young-Hwan
    • Journal of IKEEE
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    • v.15 no.2
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    • pp.143-148
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    • 2011
  • MOS (Metal-Oxide Semconductor) devices among the most sensistive of all semiconductors to radiation, in particular ionizing radiation, showing much change even after a relatively low dose. The necessity of a radiation dosimeter robust enough for the working environment has increased in the fields of aerospace, radio-therapy, atomic power plant facilities, and other places where radiation exists. The power MOSFET (Metal-Oxide Semiconductor Field-Effect Transistor) has been tested for use as a gamma radiation dosimeter by measuring the variation of threshold voltage based on the quantity of dose, and a maximum total dose of 30 krad exposed to a $^{60}Co$ ${\gamma}$-radiation source, which is sensitive to environment parameters such as temperature. The gate oxide structures give the main influence on the changes in the electrical characteristics affected by irradiation. The variation of threshold voltage on the operating temperature has caused errors, and needs calibration. These effects can be overcome by adjusting gate oxide thickness and implanting impurity at the surface of well region in MOSFET.

In-Service Identification of the Heterogeneous Zone in Petrochemical Pipelines by Using Sealed Gamma-Ray Sources $(^{60}Co,\;^{137}Cs)$

  • Kim, Jin-Seop;Jung, Sung-Hee;Kim, Jong-Bum
    • Journal of the Korean Society for Nondestructive Testing
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    • v.26 no.3
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    • pp.169-173
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    • 2006
  • In-service diagnoses of pipeline facilities are important for a systematic maintenance of them. Field applications by using sealed gamma-ray sources $(^{60}Co,\;^{137}Cs)$ were performed to identify the heterogeneous zone in the pipelines of a distillation tower and a flare stack respectively. From the results, the heterogeneous zones in the pipelines were successfully identified. In the case of the pipeline connected to the distillation tower, a vapor pocket was detected in the fluid under hydrodynamic conditions, which could explain the reason for a decrease of the flow rate. In another case, an area with some amount of catalyst deposits was found at the bottom of the gas pipeline which was connected to the flare stack. And these findings provided important information for the process operators. Diagnosis technique by using gamma radiation sources has been proven to be an effective and reliable method for providing information on a media distribution in a facility.

Impact of gamma radiation on 8051 microcontroller performance

  • Charu Sharma;Puspalata Rajesh;R.P. Behera;S. Amirthapandian
    • Nuclear Engineering and Technology
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    • v.54 no.12
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    • pp.4422-4430
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    • 2022
  • Studying the effects of gamma radiation on the instrumentation and control (I&C) system of a nuclear power plant is critical to the successful and reliable operation of the plant. In the accidental scenario, the adverse environment of ionizing radiation affects the performance of the I&C system and it leads to inaccurate and incomprehensible results. This paper reports the effects of gamma radiation on the AT89C51RD2, a commercial-off-the-shelf 8-bit high-performance flash microcontroller. The microcontroller, selected for the device under test for this study is used in the remote terminal unit for a nuclear power plant. The custom circuits were made to test the microcontroller under different gamma doses using a 60Co gamma source in both ex-situ and in-situ modes. The device was exposed to a maximum dose of 1.5 kGy. Under this hostile environment, the performance of the microcontroller was studied in terms of device current and voltage changes. It was observed that the microcontroller device can operate up to a total absorbed dose of approximately 0.6 kGy without any failure or degradation in its performance.

The Enhancement of Skin Sparing by Tray Materials for High Energy Photon Beam (고에너지 광자선치료에서 고정판 흡수물질을 이용한 피부보호효과의 향상)

  • Chu, Sung-Sil;Lee, Chang-Geol;Kim, Gwi-Eon
    • Radiation Oncology Journal
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    • v.11 no.2
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    • pp.449-454
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    • 1993
  • The skin sparing effect associated with high energy x-ray or gamma ray beams may be reduce or lost under certain conditions of treatment. Current trends in using large fields. Shield carrying trays, compensating filters, and isocentric methods of treatment have posed problems of increased skin dose which sometimes become a limiting factor in giving adquate tumor doses. We used the shallow ion chamber to measure the phantom surface dose and the physical treatment variables for Co-60 gamma ray, 4MV and 10 MV x-ray beam. The dependence of percent surface dose on field sizes, atomic number of the shielding tray materials and its distance from the surface for 4, 10MV x-rays and Co-60 gamma ray is qualitatively similar. The use of 2 mm thick tin filter is recommended for situations where a low atomic number tray is introduced into the beam at distances less than 15 cm from the surface and with the large field sized for 4 MV x-ray beam. In case of Co-60 gamma ray, the lead glass tray is suitable for enhancement of skin sparing. Also, the filter distance should be as large as possible to achieve substantial skin sparing.

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The Study of Radiation Sensitivity on Fiber Bragg Grating Written in Photo-sensitive Optical Fibers (광민감 광섬유로 제작한 광섬유 브래그 격자 센서의 방사선 민감도에 대한 연구)

  • Kim, Jong-Yeol;Lee, Nam-Ho;Jung, Hyun-Kyu
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.18 no.8
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    • pp.2023-2028
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    • 2014
  • In this study, we studied the effect of $Co^{60}$ gamma-radiation on the FBGs written in photo-sensitive and commercial Ge-doped single-mode optical fibers. The FBGs were exposed to gamma-radiation up to a dose of 17.8 kGy at the dose rate of 300 Gy/min. According to the experimental data and analysis results, the lowest Bragg wavelength shift (18 pm) was obtained by a grating written in photosensitive fiber without $H_2$-loading. Also, we confirmed that the H2 loading process has considerably more influence on the Bragg wavelength shift change under gamma radiation than $GeO_2$ contents in the fiber core.