• Journal of Communications and Networks
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• 제13권6호
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• pp.664-677
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• 2011

In order to control interference and improve spectrum efficiency in the femtocell and macrocell overlaid system (FMOS), we propose a joint frequency bandwidth dynamic division, clustering and power control algorithm (JFCPA) for orthogonal-frequency-division-multiple access-based downlink FMOS. The overall system bandwidth is divided into three bands, and the macro-cellular coverage is divided into two areas according to the intensity of the interference from the macro base station to the femtocells, which are dynamically determined by using the JFCPA. A cluster is taken as the unit for frequency reuse among femtocells. We map the problem of clustering to the MAX k-CUT problem with the aim of eliminating the inter-femtocell collision interference, which is solved by a graph-based heuristic algorithm. Frequency bandwidth sharing or splitting between the femtocell tier and the macrocell tier is determined by a step-migration-algorithm-based power control. Simulations conducted to demonstrate the effectiveness of our proposed algorithm showed the frequency-reuse probability of the FMOS reuse band above 97.6% and at least 70% of the frequency bandwidth available for the macrocell tier, which means that the co-tier and the cross-tier interference were effectively controlled. Thus, high spectrum efficiency was achieved. The simulation results also clarified that the planning of frequency resource allocation in FMOS should take into account both the spatial density of femtocells and the interference suffered by them. Statistical results from our simulations also provide guidelines for actual FMOS planning.

• 생명과학회지
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• 제19권8호
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• pp.1062-1066
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• 2009

N-Acetylglucosamine kinase (GlcNAc kinase or NAGK; EC 2.7.1.59)는 GlcNAc를 인산화하여 GlcNAc-6-phosphate를 만드는 효소이다. 효소자체에 대한 자세한 연구에도 불구하고 포유류에서NAGK의 표현에 대한 연구는 거의 없다. 배양한 흰쥐의 해마신경세포에서 NAGK은 세포체/가지돌기 영역에서 클러스터(cluster)를 형성한다. 본 연구에서는 가지돌기의 긴 축에서부터 가쪽으로 돌출되는 NAGK 클러스터에 대하여 연구하였다. 배양한 해마신경세포를 NAGK와 다양한 연접표지단백질에 대한 항체로 이중염색한 결과 NAGK 클러스터가 가지돌기의 바닥에는 있었지만 억제성 연접후부위에는 존재하지 않았다. 또한 흰쥐 전뇌(forebrain)의 균질액(homogenate, BH), 연접체(synaptosome, S), 연접후치밀질(postsynaptic density, PSD) 분획을 NAGK 항체로 면역염색한 결과 NAGK는 연접체에는 있었지만 PSD 분획에는 존재하지 않았다. 이러한 결과들은 NAGK가 가지돌기가시(spine)의 바닥쪽으로 돌출됨을 의미한다.

• Clinical and Experimental Pediatrics
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• 제55권4호
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• pp.128-135
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• 2012

Purpose: Unbalanced diets and decreased physical activity have contributed to increased prevalence of obesity and metabolic syndrome in adolescents. We have performed a systematic review and data analysis to examine the association between dietary pattern and metabolic syndrome risk factors in adolescents. Methods: We searched the PubMed and BioMedLib databases for appropriate articles published during the past 10 years and selected 6 articles. The studies reviewed applied factor analysis or cluster analysis to extract dietary patterns. For data analysis, we examined the association between dietary patterns and the prevalence of metabolic syndrome risk factors using data of 3,168 adolescents (13 to 18 years) obtained from 4 consecutive Korean Nutrition Health and Nutrition Examination Surveys (1998, 2001, 2005, and 2007 to 2009). Results: Our systematic review confirmed that western dietary patterns are positively associated with metabolic syndrome risk factors such as obesity and elevated triglycerides, while traditional dietary patterns were negatively associated. Data analysis found that the number of adolescents aged 16 to 18 years who had "Rice & Kimchi" dietary pattern decreased, while the number having western dietary patterns increased during the 1998 to 2009 time frame. There were no changes in the dietary patterns in adolescents aged 13 to 15 years. The risk of elevated serum triglycerides and reduced serum high density lipoprotein cholesterol was high in the "Rice & Kimchi" dietary pattern compared to the other dietary pattern groups. Conclusion: Because adolescents' dietary patterns are changing continuously and have long-term effects, further studies on the dietary patterns of adolescents and their health effects into adulthood are necessary.

• 한국수산과학회지
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• 제35권2호
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• pp.130-134
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• 2002

볼락의 난소는 낭상형이며, 다수의 난소소엽으로 구성되어 있었다. 난황축적 이전의 난모세포들은 난소소엽의 결체성 조직에 매몰되어 관찰되었다. 난모세포는 성장하면서 난소강으로 돌출되어 난병 유사구조를 가지고 포도송이와 같은 구조를 나타냈다 난소 소엽내에 매몰되어있는 직경 약 20$\mu$m 크기의 초기 난모세포에서 난황과립과 방사대는 관찰되지 않았다 직경 약 80$\mu$m의 초기 난모세포의 난병 유사구조 세포질에서는 전자밀도가 높은 난황과려들이 다수 관찰되었으나, 방사대의 pore canal system에서 음세포작용은 관찰되지 않았다. 이 시기에 난병 유사구조에서는 미세섬유, 발달된 소포체와 미토콘드리아, 전자밀도가 낮은 과립상 물질 그리고 활성화된 multivesicular body들이 관찰되었다. 이러한 결과들은 볼락의 난병 유사구조는 난모세포의 부착과 초기 난모세포의 외재적 난황축적에 관여함을 시사하는 것이라고 할 수 있다.

• Restorative Dentistry and Endodontics
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• 제38권2호
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• pp.65-72
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• 2013

Objectives: To evaluate the inhibitory effect of ursolic acid (UA)-containing composites on Streptococcus mutans (S. mutans) biofilm. Materials and Methods: Composite resins with five different concentrations (0.04, 0.1, 0.2, 0.5, and 1.0 wt%) of UA (U6753, Sigma Aldrich) were prepared, and their flexural strengths were measured according to ISO 4049. To evaluate the effect of carbohydrate source on biofilm formation, either glucose or sucrose was used as a nutrient source, and to investigate the effect of saliva treatment, the specimen were treated with either unstimulated whole saliva or phosphate-buffered saline (PBS). For biofilm assay, composite disks were transferred to S. mutans suspension and incubated for 24 hr. Afterwards, the specimens were rinsed with PBS and sonicated. The colony forming units (CFU) of the disrupted biofilm cultures were enumerated. For growth inhibition test, the composites were placed on a polystyrene well cluster, and S. mutans suspension was inoculated. The optical density at 600 nm ($OD_{600}$) was recorded by Infinite F200 pro apparatus (TECAN). One-way ANOVA and two-way ANOVA followed by Bonferroni correction were used for the data analyses. Results: The flexural strength values did not show significant difference at any concentration (p > 0.01). In biofilm assay, the CFU score decreased as the concentration of UA increased. The influence of saliva pretreatment was conflicting. The sucrose groups exhibited higher CFU score than glucose group (p < 0.05). In bacterial growth inhibition test, all experimental groups containing UA resulted in complete inhibition. Conclusions: Within the limitations of the experiments, UA included in the composite showed inhibitory effect on S. mutans biofilm formation and growth.

• 대한화학회지
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• 제60권1호
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• pp.9-15
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• 2016

폭발성능이 높은 HMX와 폭발성능은 떨어지지만 안정성이 높은 LLM-116의 분자복합체인 HMX/LLM-116 공결정(cocrystal)의 폭발 속도, 폭발 압력 그리고 열역학적 안정성에 대하여 이론적으로 연구하였다. 각 분자 구조는 B3LYP/cc-pVTZ 수준까지 최적화 하였으며 가장 약한 방아쇠 결합(trigger bond)과 클러스터에 대한 결합에너지를 계산 하여 열역학적 안정성을 확인하였다. 보다 정확한 에너지를 계산하기 위해 MP2 이론 수준에서 한 점(single point) 에너지를 계산하였으며, monte carlo integration 계산을 통해 밀도를 계산 하였다. 엔탈피는 CBS-Q 이론 수준에서 계산하였으며, 폭발 속도와 폭발 압력은 Kamlet-Jacobs 방정식을 이용하여 계산하였다.

• 천문학회보
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• 제37권2호
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• pp.73.2-73.2
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• 2012

Matusoka & Kawara (2010) showed that the number density of the most massive galaxies (log $M/M_{\odot}=11.5-12.0$) increases faster than that of the next massive group (log $M/M_{\odot}=11.0-11.5$) during 0 < z < 1. This appears to be in contradiction to another important empirical concept of "downsizing". We attempt to understand the two observational findings in the context of the hierarchical merger paradigm using semi-analytic techniques. Our models closely reproduce the result of Matusoka & Kawara (2010). Downsizing can also be understood as larger galaxies have on average smaller assembly ages but larger stellar ages. Our fiducial models further reveal the details on the history of stellar mass growth of massive galaxies. The most massive galaxies (log $M/M_{\odot}=11.5-12.0$ at z=0), which are mostly brightest cluster galaxies, obtain roughly 70% of their stellar components via merger accretion. The role of merger accretion monotonically declines with galaxy mass: 45% for log $M/M_{\odot}=11.0-11.5$ and 20% for log $M/M_{\odot}=10.5-11.0$ at z = 0. The specific accreted stellar mass rates via galaxy mergers decline very slowly during the whole redshift range, while the specific star formation rates sharply decrease with time. In the case of the most massive galaxies, merger accretion becomes the most important channel for the stellar mass growth at z ~ 2. On the other hand, in-situ star formation is always the dominant channel in the $L_*$ galaxies.

• 한국환경과학회지
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• 제11권3호
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• pp.215-225
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• 2002

In order to evaluate the relationship between geochemical characteristics and benthic facies of the sediments from the Oenaro Island where red tide proliferation is first observed every year including this year, surface and short multiple core sediment samples were analyzed in terms of geochemical and benthic facies variation. The contents of organic carbon, carbonate, and sulfide gas were relatively low. The variation in C/N ratios, which indicate nature of organic carbon, suggested that the organic carbon recorded in the study area is composed of mixtures of marine and terrigenous organic matters. The concentration of minor elements found at the surface and multiple core sediment samples were also low as well as the enrichment factors(Ef) for the seven heavy metals indicated that the sediment of this area is not polluted significantly. The macrobenthic faunal community comprised 61 species, and their mean density was 708 ind./m2. Polychaete worms were major taxa of this benthic community. A crustacean amphipod, Melita sp. was the most abundant species accounted for 20.7% of total abundance, and the small polychaetes such as Heteromastus filiformis, Paralacydonia poradoxa, Magelona japonica and Sigambra tentaculata were the next dominant species. The macrobenthos around the Oenaro Island were more diverse and abundant than that in Gamak Bay. The benthic communities in the study area sustained somewhat different species composition based on the cluster analysis and the MDS ordination. The benthic community health condition at three stations seemed to be unbalanced, and slightly polluted based on the biological index such as BPI and BC. There was no clear relationship between the geochemistry characteristic and the benthic faunal facies attributed by the micro-algal blooms in this coastal area.

• 정보관리연구
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• 제43권4호
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• pp.31-48
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• 2012

본 연구는 네트워크 연결망 분석 방법을 적용하여 대학도서관 직무간의 연결성을 분석하였다. 서울소재 32개 대학도서관 545명의 직무를 대상으로 빈도 및 네트워크 분석을 실시하였으며, 규모에 따라 2개 그룹으로 구분하여 2차 분석을 실시함으로써, 밀도 및 연결성의 차이를 파악하였다. 분석 결과는 다음과 같이 나타났다. 첫 번째, 다양한 직무를 가진 대규모 도서관이 소규모 도서관보다 낮은 밀도와 느슨한 연결성을 보였다. 두 번째, 소규모 도서관이 3개의 직군으로 클러스터를 형성한 반면, 대규모 도서관은 1개의 기술 업무 영역과 3개의 다양한 이용자 서비스 영역으로 클러스터를 형성하였다. 세 번째, "목록", "분류"와 같이 특정성이 높은 직무들이 대규모 도서관에서는 상대적으로 낮은 연결 중심성을 보인 반면, 소규모 도서관에서는 높은 연결 중심성을 보였다.

• 한국정보전자통신기술학회논문지
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• 제1권3호
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• pp.69-76
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• 2008

본 논문에서는 Mountain clustering 알고리즘을 이용한 Fuzzy Radial Basis Function Neural Network(FRBFNN)의 규칙 수를 자동생성 방법을 제시한다. FRBFNN은 기존 RBFNN에서 가우시안이나 타원형 형태의 특정 RBF를 사용하는 구조와 달리 클러스터의 중심값과의 거리에 기반을 둔 멤버쉽함수를 사용하여 전반부의 공간 분할 및 활성화 레벨을 결정한다. 또한 분할된 로컬영역에서의 입출력 특성을 나타내는 퍼지규칙의 후반부로서 고차 다항식을 고려하였다. 본 논문에서는 데이터의 밀집도에 기반을 두어 클러스터링을 수행하는 Mountain clustering 알고리즘을 사용하여 적합한 퍼지 규칙(클러스터)의 수와 클러스터의 중심값을 자동적으로 생성하는 방법을 제안한다. Mountain clustering으로부터 구해진 클러스터의 중심은 멤버쉽 값을 결정하는데 사용되며, Weighted Least Square Estimator (WLSE) 알고리즘을 사용하여 후반부 다항식의 계수를 추정한다. 제안된 알고리즘은 비선형 함수 모델링에 적용하여 성능의 우수성과 알고리즘의 타당성을 보인다.