• Journal of the Korean association of regional geographers
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• v.15 no.1
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• pp.115-137
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• 2009

Recently, industrial locations have faced changing trends under the influence of emerging industries as well as advanced new technologies. So the purpose of this study is to analyze the spatial distribution and locational factors of biotechnology industry formed around the Seoul Metropolitan area and Daejeon city, both of which are centers of Korean biotechnology industry, and is also to identifytheir locational characteristics. Major results of this study can be outlined as follows: First, from the mid 1990' s to 2000, Korean biotechnology industry has rapidly developed owing to central and local governmental support policies and systems as well as changes in domestic economic environment due to Korean financial crisis. Secondly, it was found that spatial distribution of Korean biotechnology industry converged on the Seoul Metropolitan area till 1990, but shifted from there to Daejeon and Chungcheong area from 1990 to 2000. Particularly after 2000, positive local governmental efforts to attract biotechnology players have driven the spatial distribution of biotechnology industry to shift from Seoul Metropolitan area and Daejeon or adjacent area gradually to other profitable locations. In terms of locational factors, it was found that the locations of Korean biotechnology industry converged primarily on university or college campus and biotechnology venture center, particularly on locations adjacent to superhighway or expressway. Locational factors varied depending on region, industrial type and business growth phase. Therefore, it is advisable that our central and local government should make and implement practical and useful policies in favor of biotechnology business depending on region, industrial type, business growth phase, rather than depending on uniform locational policies.

• Journal of Intelligence and Information Systems
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• v.14 no.1
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• pp.1-17
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• 2008

Data mining is defined as the process of discovering meaningful and useful pattern in large volumes of data. In particular, finding associations rules between items in a database of customer transactions has become an important thing. Some data structures and algorithms had been proposed for storing meaningful information compressed from an original database to find frequent itemsets since Apriori algorithm. Though existing method find all association rules, we must have a lot of process to analyze association rules because there are too many rules. In this paper, we propose a new data structure, called a Frequent Pattern Network (FPN), which represents items as vertices and 2-itemsets as edges of the network. In order to utilize FPN, We constitute FPN using item's frequency. And then we use a clustering method to group the vertices on the network into clusters so that the intracluster similarity is maximized and the intercluster similarity is minimized. We generate association rules based on clusters. Our experiments showed accuracy of clustering items on the network using confidence, correlation and edge weight similarity methods. And We generated association rules using clusters and compare traditional and our method. From the results, the confidence similarity had a strong influence than others on the frequent pattern network. And FPN had a flexibility to minimum support value.

• Journal of KIISE:Computer Systems and Theory
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• v.31 no.12
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• pp.726-734
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• 2004

This paper presents a facial animation method that enables the user to select a sequence of facial frames from the facial expression space, whose level of details the user can select hierarchically Our system creates the facial expression space from about 2400 captured facial frames. To represent the state of each expression, we use the distance matrix that represents the distance between pairs of feature points on the face. The shortest trajectories are found by dynamic programming. The space of facial expressions is multidimensional. To navigate this space, we visualize the space of expressions in 2D space by using the multidimensional scaling(MDS). But because there are too many facial expressions to select from, the user faces difficulty in navigating the space. So, we visualize the space hierarchically. To partition the space into a hierarchy of subspaces, we use fuzzy clustering. In the beginning, the system creates about 10 clusters from the space of 2400 facial expressions. Every tine the level increases, the system doubles the number of clusters. The cluster centers are displayed on 2D screen and are used as candidate key frames for key frame animation. The user selects new key frames along the navigation path of the previous level. At the maximum level, the user completes key frame specification. We let animators use the system to create example animations, and evaluate the system based on the results.

• Journal of Preventive Medicine and Public Health
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• v.29 no.4 s.55
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• pp.877-897
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• 1996

In recent years, the Korean Medical Association has undertaken the feat of establishing the Korean Standard Terminology of Medical Procedures with the dedicated help of 32 medical academic societies. However, because the project is being conducted by several different circles, it has yet to see a clear system of classification. This thesis, therefore, proposes the three principles of scientific properties, usefulness and ideology as the basis for classification system and has developed the Classification System of Medical Procedures in Korea upon their foundation. The methodology and organization of this thesis as follows. First, by adopting scientific classification system of Feinstein(1988), an analysis of the classification systems of the medical procedures in the United States, Japan, Taiwan, WHO was carried out to reveal the framework and the basic principles in each system. Second, the direction of classification system has been constructed by applying the normative principle of medical field in order to show the future direction of the medical field and realize its ideology. Third, a finalized framework for the classification system will be presented as based on the direction of classification system. Of the three basis principles mentioned above, the analysis on the principles of usefulness was left out of this thesis due to the difficulty of establishing specific standards of analysis. The results of the study are as follows. The overall structure of the thesis is aimed at showing the 'Prevention-Therapy-Rehabilitation' quality of comprehensive health care and consists of six chapters; I. Prevention and Health Promotion II. Evaluation and Management III. Diagnostic Procedures IV. Endoscopy V. Therapeutic Procedures VI. Rehabilitation Chapter three Diagnostic Procedures is divided into four parts : Functional Diagnosis, Visual Diagnosis, Pathological Diagnosis, Biopsy and Sampling. Chapter five Therapeutic Procedures is divided into Psychiatry, Non-Invasive Therapy, Invasive Therapy, Anaesthesia and Radiation Oncology. Of these sub-divisions, Functional Diagnosis, Biopsy and Sampling, Endoscopy and Invasive Therapy employs the anatomical system of classification. On the other hand, Visual Diagnosis, Pathological Diagnosis, Anesthesia and Diagnostic Radiology, namely those divisions in which there is little or no overlapping in services with other divisions, used the classification system of its own division. The classification system introduced in this thesis can be further supplemented through the use of the cluster analysis by incorporating the advice and assistance of other specialists.

• Journal of KIISE:Computer Systems and Theory
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• v.26 no.7
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• pp.813-826
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• 1999

실시간 멀티미디어 응용의 등장으로 멀티캐스트와 QoS(Quality of Service) 지원이 필수적인 망 서비스로 부각되고 있다. 이에, ATM 기반의 인터넷에서 IP 멀티캐스트의 효율적인 처리를 위하여 MARS(Multicast Address Resolution Server)가 제안되었고, 기존의 최선 서비스 기반의 인터넷에서 QoS(Quality of Service)를 지원하기 위하여 RSVP(Resource Reservation Protocol)가 제안되었다. 본 논문에서는 ATM 망에서 QoS가 지원되는 IP 멀티캐스트 서비스를 제공하기 위하여 MARS 구조에서 RSVP를 지원하는 두 가지 방안을 제안하고, 시뮬레이션을 통하여 그 성능을 분석하였다. 제안하는 두 가지 방법은 각각 'RSVP 전 홉 노드 방식'과 'MARS 서버 방식'이라 명명하였다. RSVP 전 홉 노드 방식은 송신원으로부터 ATM 망으로 진입하는 노드와 수신원을 향하여 ATM 망을 진출하는 노드 간에 각각 일대일 양방향 VC를 설정하여 멀티캐스트 그룹에 속하는 수신원들이 보내는 자원 예약 메시지를 ATM 망에서 전송하는 방안이다. MARS 서버 방식은 ATM 망을 진출하는 노드와 MARS 서버간에 MARS 제어 메시지 교환을 위해 존재하는 ATM VC를 사용하여 RSVP의 자원 예약 메시지를 전송하고, MARS 서버가 RSVP 자원 예약 메시지를 처리하도록 그 기능을 확장함으로써 ATM 망에서 필요로 하는 제어 VC 수를 절약할 수 있는 방안이다. 시뮬레이션을 통하여, MARS 서버 방식은 ATM 제어 VC의 수를 절약할 수 있을 뿐 아니라 경우에 따라 RSVP 자원 예약 메시지 전달 지연을 줄일 수도 있음을 볼 수 있었다. 그러나, MARS 클러스터 내에 동시에 존재하는 RSVP 흐름이 많을 때에는 MARS 서버 방식의 경우 MARS 서버에서의 병목 현상으로 인해 성능이 저하될 수 있다.Abstract Emerging real time multimedia applications require multicast service with a QoS(Quality of Service) support. An overlay service architecture MARS(Multicast Address Resolution Server) is proposed to support IP multicast over an ATM network, and a resource reservation protocol RSVP is proposed to provide QoS support in the Internet which is originally based upon best effort service only. In this paper, we propose two schemes to support IP multicast service with QoS support over ATM networks: 'RSVP Previous Hop Node(RPHN) scheme' and 'MARS server based scheme'. In RPHN scheme, the RSVP reservation messages are transported via one-to-one ATM control VC from the egress nodes to the ingress nodes of the the multicast flow set up between each pair of nodes. The RSVP message processing occurs at the ingress nodes of the multicast flow. Whereas, in the MARS server based scheme, the RSVP reservation messages are transported via the MARS control VCs between the egress nodes and the MARS server. The RSVP message processing burden is imposed at MARS server in this scheme. For MARS server based scheme, no additional ATM VC is required for RSVP reservation message transmission, while the processing burden at the MARS server is high. Simulation results show that the MARS server based scheme, may accomplish RSVP reservation message delivery with smaller delay as well as saving of the number of ATM VCs. When the number of simultaneous RSVP flows in the MARS cluster is large, however, MARS based scheme may suffer performance degradation since MARS server becomes a performance bottleneck.

• Journal of Distribution Science
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• v.13 no.1
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• pp.27-33
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• 2015

Purpose - The ICT market in the EU is lagging behind that of the US; however, algorithm and software development within the EU have grown steadily, and they involve focusing on the creative cultural convergence conceptualized as part of Horizon 2020 and connecting neighboring markets in the EE and the Mediterranean region. It is essential to study the requirements to market the EU's creative ICT development in emerging industrial countries after examining its applicability in these countries. Research design, data, and methodology - This study deals with data pertaining to the EU's creative industry and competitive edge. The global cultural expansion of the EU facilitates a new concept involving not only low-cost IT products to enhance local cultural artifacts through R&D and the construction of efficient infrastructure services, but also information exchange with a realistic commercialization of the technology that can be applied for creative cultural localization. In the European industry, research on algorithms has been applied for the benefit of consumers. We investigated how the process is conducted in the EU. Results - Europe needs to adjust its economic structure to the local culture as part of IT distribution convergence. The convergence has been converted into a production algorithm with IT in the form of low-cost production. This is because there is an attempt to improve the quality of transport infrastructure, workforce availability, and the distribution of the distance to the local industries and consumers, using IT algorithms. Integrated into the manufacturing industry, based on the ICT infrastructure and solutions, smart localized regional clusters are formed with the help of grafting. Europe has own strategy to increase the number of hub-and-spoke cities. Europe is now becoming integrated, with an EPC system for regional cooperation rather than national competition in ICT technology. Europe has also been recognized in this study as changing the step-by-step paradigm for global competitiveness through new creative culture industries. Conclusions - As a result, there are several ways of converging with others through EU R&D intensity; therefore, the EU can be seen as successfully increasing marginal value, which is useful in developing a special industrial cluster or local cultural cities that create converged development by connecting people and objects with IT. In fact, when compared to the US, Europe has a strong culture and the car industries have a tendency to overshadow the IT industries with integration of services in IT distribution. Considering the rapid environmental changes, the convergence of IT services is likely to take place in Europe, similar to the pharmaceutical industry and the automotive industry. This requires a focus on human resources and automated systems management. The trend is to move away from low-wage industries, switched to key personnel centers of the local university-industry. EU emphasizes the creation of IT market demand in Europe involving local cultural convergence for marketing as the second step to strengthen the economic hub-and-spoke areas.

• KIPS Transactions on Computer and Communication Systems
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• v.8 no.8
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• pp.191-200
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• 2019

In an Ad-hoc network, a method of time synchronizing all the nodes in a network centering on one reference node can be used. A representative algorithm based on a reference node is Flooding Time Synchronization Protocol (FTSP). In the process of sending and receiving messages, predictable and unpredictable delays occur, which should be removed because it hinders accurate time synchronization. In multi-hop communications, hop delays occur when a packet traverses a number of hops. These hop delays significantly degrade the synchronization performance among nodes. Therefore, we need to find a method to reduce these hop delays and increase synchronization performance. In the FTSP scheme, hop delays can be greatly increased depending on the position of a reference node. In addition, in FTSP, a node with the smallest node ID is elected as a reference node, hence, the position of a reference node is actually arbitrarily determined. In this paper, we propose an optimal reference node election algorithm to reduce hop delays, and compare the performance of the proposed scheme with FTSP using the network simulator OPNET. In addition, we verify that the proposed scheme has an improved synchronization performance, which is robust to topology changes.

• Journal of the Korea Society for Simulation
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• v.31 no.3
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• pp.1-10
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• 2022

Defense fields widely operate unmanned systems to lower vulnerability and enhance combat effectiveness. In the navy, swarm unmanned surface vehicles(USVs) form a cluster within communication range, share situational awareness information among the USVs, and cooperate with them to conduct military missions. This paper proposes an interface system, i.e., Interface Adapter System(IAS), to achieve inter-USV and intra-USV interoperability. We focus on the mission planning subsystem(MPS) for interoperability, which is the core subsystem of the USV to decide courses of action such as automatic path generation and weapon assignments. The central role of the proposed system is to exchange interface data between MPSs and other subsystems in real-time. To this end, we analyzed the operational requirements of the MPS and identified interface messages. Then we developed the IAS using the distributed real-time middleware. As experiments, we conducted several integration tests at swarm USVs simulation environment and measured delay time and loss ratio of interface messages. We expect that the proposed IAS successfully provides bridge roles between the mission planning system and other subsystems.

• Genomics & Informatics
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• v.20 no.4
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• pp.44.1-44.13
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• 2022

Brugada syndrome (BS) is an autosomal dominant inheritance cardiac arrhythmia disorder associated with sudden death in young adults. Thailand has the highest prevalence of BS worldwide, and over 60% of patients with BS still have unclear disease etiology. Here, we performed a new viral metagenome analysis pipeline called VIRIN and validated it with whole genome sequencing (WGS) data of HeLa cell lines and hepatocellular carcinoma. Then the VIRIN pipeline was applied to identify viral integration positions from unmapped WGS data of Thai males, including 100 BS patients (case) and 100 controls. Even though the sample preparation had no viral enrichment step, we can identify several virus genes from our analysis pipeline. The predominance of human endogenous retrovirus K (HERV-K) viruses was found in both cases and controls by blastn and blastx analysis. This study is the first report on the full-length HERV-K assembled genomes in the Thai population. Furthermore, the HERV-K integration breakpoint positions were validated and compared between the case and control datasets. Interestingly, Brugada cases contained HERV-K integration breakpoints at promoters five times more often than controls. Overall, the highlight of this study is the BS-specific HERV-K breakpoint positions that were found at the gene coding region "NBPF11" (n = 9), "NBPF12" (n = 8) and long non-coding RNA (lncRNA) "PCAT14" (n = 4) region. The genes and the lncRNA have been reported to be associated with congenital heart and arterial diseases. These findings provide another aspect of the BS etiology associated with viral genome integrations within the human genome.

• Journal of Korea Port Economic Association
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• v.39 no.2
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• pp.77-95
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• 2023

The regional infrastructure industries of Gwangyang City, the subject of this study, are Gwangyang Port and Gwangyang Steel Mill. Therefore, it is necessary to analyze the regional economic ripple effects of the port logistics industry in Gwangyang City. In this study, a multi-stage approach using the RW and the LQ methodology using the national input-output tables in 2015 and 2019 is used to prepare the regional interindustry analysis chart in Gwangyang City, and an exogenous demand induction model that reclassified the port logistics industry was applied. Through this, the purpose of this study was to provide policy implications by figuring out the regional economic ripple effects of the port logistics industry quantitatively in Gwangyang City. As a result of the analysis, the industries with high production inducement effect and forward/backward linkage effect of the port logistics industry in Gwangyang City were analyzed as manufacturing, transportation, land and air logistics sectors. And the industries in which the added value inducement effect and the employment inducement effect were analyzed as an industry related to the service industry. Therefore, it is necessary to prepare support measures to foster the port logistics industry as a way to promote these industries and revitalize the local economy of Gwangyang City. To this end, it is desirable to improve policies and systems for the vitalization of the Gwangyang port maritime cluster and provide various policy support for the port logistics industry in Gwangyang City. This study is meaningful in suggesting policy implications for the regional economy of Gwangyang City based on the results of exogenous analysis of the port logistics industry in small and medium-sized cities. However, It seems that further studies related to this will be needed in the future.