• Title/Summary/Keyword: Cluster Center

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The politic plan research for furniture industrial activation in the northern part of Gyeonggi-Province

  • Im, Kwang-Soon;Kim, Houn-Chul
    • Journal of the Korea Furniture Society
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    • v.21 no.6
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    • pp.515-524
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    • 2010
  • In line with the government's policies for localization, furniture industry in the northern area in Gyeoggi-province at presence has been operated by several furniture industrial complexes in the region in small scale, but now it should be considered from overall view of furniture industry in order to develop more competitive industry. As a matter of this fact, Gyeonggi-province should be engaged in planning to make various industrial clusters of the furniture-related industry based on the northern area of province at structural as well as politic aspects, with the help of the analyzed status of the current furniture industry in region, in supporting them by the systemized policies and developing the overall program to foster furniture as an international-competitive industry. Therefore this study suggested 'furniture industry center' which will exclusively handle and maintain the network of each furniture company in the northern area of Gyeonggi-province and 'high-tech furniture industry complex' to keep pace with the globalization and to be competitive internationally and also 'common brand business' for the cooperation at technical phase. In order to realize and vitalize such suggestions, it is urgently necessary that the network consists of the furniture companies and the expert of the related department in local universities as the main body for furniture industry, of course Gyeonggi-province as well.

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Science & Technology Business: The Role of International Science Business Belt in Korea (과학기술 비즈니스(S&T Business): 과학벨트(ISBB)의 역할)

  • Lee, Won Cheul;Choi, Jong-In
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.11 no.4
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    • pp.139-148
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    • 2016
  • The importance of technology commercialization is being emphasized more and more, but high technology excellence does not always lead to a successful business. In addition, companies that invest heavily in basic research and technology development are also not always able to guarantee high profits. This is due to the technical problems when present in step research and development levels are difficult to commercialize. And the market will not work rationally is also the cause of the problem. Therefore, to effectively utilize the resources necessary to ensure such partners to build alliances and cooperation with external funding or manpower is crucial to commercialize the research results of basic science successfully. In previous studies, it has been made many studies in accordance with the approach to the technology (e.g. Research and Development, Management of Technology, Technology Innovation, etc.). But the study of technology commercialization point of view is not being done much. This study should explores the available business required, or realized in the process of researching the basic science and trying to understand the imperfections of the market through the property of technology (tacit knowledge, objectified value of technology and the information asymmetry between innovation subjects, etc.). In addition, this paper, we try to focus on a strategic approach to the role of International Science Business Belt (ISBB) with success in science and technology business as appropriate countermeasures about breaking the 'Valley of Death.

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Diversity of vir Genes in Plasmodium vivax from Endemic Regions in the Republic of Korea: an Initial Evaluation

  • Son, Ui-han;Dinzouna-Boutamba, Sylvatrie-Danne;Lee, Sanghyun;Yun, Hae Soo;Kim, Jung-Yeon;Joo, So-Young;Jeong, Sookwan;Rhee, Man Hee;Hong, Yeonchul;Chung, Dong-Il;Kwak, Dongmi;Goo, Youn-Kyoung
    • Parasites, Hosts and Diseases
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    • v.55 no.2
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    • pp.149-158
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    • 2017
  • Variant surface antigens (VSAs) encoded by pir families are considered to be the key proteins used by many Plasmodium spp. to escape the host immune system by antigenic variation. This attribute of VSAs is a critical issue in the development of a novel vaccine. In this regard, a population genetic study of vir genes from Plasmodium vivax was performed in the Republic of Korea (ROK). Eighty-five venous blood samples and 4 of the vir genes, namely vir 27, vir 21, vir 12, and vir 4, were selected for study. The number of segregating sites (S), number of haplotypes (H), haplotype diversity (Hd), DNA diversity (${\pi}$ and ${\Theta}_w$), and Tajima's D test value were conducted. Phylogenetic trees of each gene were constructed. The vir 21 (S=143, H=22, Hd=0.827) was the most genetically diverse gene, and the vir 4 (S=6, H=4, Hd=0.556) was the opposite one. Tajima's D values for vir 27 (1.08530, P>0.1), vir 12 (2.89007, P<0.01), and vir 21 (0.40782, P>0.1) were positive, and that of vir 4 (-1.32162, P>0.1) was negative. All phylogenetic trees showed 2 clades with no particular branching according to the geographical differences and cluster. This study is the first survey on the vir genes in ROK, providing information on the genetic level. The sample sequences from vir 4 showed a clear difference to the Sal-1 reference gene sequence, whereas they were very similar to those from Indian isolates.

Estimation of Nominal Frequency of Whangjongeum by Acoustical Analysis of Old Pyeongyeongs (유물 편경의 음향 분석을 통한 아악 황종음고의 추정)

  • Yoo, June-Hee;Park, Jeong-Woo;Bae, Dae-Sung;Kim, Hyung-Jun;Sung, Keong-Mo;Noh, Jung-Uk;Koh, Hyun-Woo
    • The Journal of the Acoustical Society of Korea
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    • v.30 no.8
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    • pp.421-427
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    • 2011
  • This study aimed to figure out the numbers and note distributions and sexagenary cycles of old pyeongyoungs systematically, and estimate the nominal frequency of whangjongeum, the Korean tradition pitch standard. As a total 214 old stones in the National Palace Museum, the National Kukak Center, the Kukak National High School were counted by notes and sexagenaries. The nominal frequencies of 17 old whangjong stones' sounds were categorized by cluster analysis method. Using nominal frequencies of stones according to their sexagenaries and Korean traditional intonation were used to estimate the nominal frequencies of the whangjong. The nominal frequency can be estimated by 22 Keychuk stones as 266.9 Hz, by Cheongyu and Gabja stones as 262.4~262.5 Hz, and by Gabjin, Sowha 12 and Sowha 13 as Estimating by 22 Kyechuk stones which were matched with the records. These results seem to be more reliable, because it is based on the whol samples of old pyeongyoungs, while the former studies have been based on couples of whangjong stones' sounds.

Cancer survivor's dietary safety management awareness and competency type (암 생존자의 식생활 안전관리 인식과 역량 유형)

  • Kim, Yun Hwa
    • Journal of Nutrition and Health
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    • v.53 no.5
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    • pp.532-546
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    • 2020
  • Purpose: Although the number of cancer survivors is increasing because of early diagnosis and better treatment, they are worried about relapses and metastasis. This study examined the dietary safety management awareness, capacity, and behavior of cancer survivors. Methods: Data were collected from 233 cancer survivors in Daegu and Gyeongbuk areas using a self-administered 5-Likert questionnaire from March to May 2018. Frequency analysis, one-way analysis of variance, factor analysis, reliability analysis, and correlation analysis were analyzed using the SPSS. Results: The average score for each factor was as follows: importance of weight management (3.83), education requirement (3.79), unhealthy diet (reverse, 3.64), food safety anxiety (3.34), lack of awareness of over and malnutrition (reverse, 3.26), obsession (3.23), cooking capacity (3.16), health-function pursuit (3.04), balanced diet (2.93), and chronic disease anxiety (2.64). The average dietary safety competency factors were significantly lower among the male survivors, aged 60-80 years, lower economic condition, and less nutritional supplement intake. Female survivors comprised the highest proportion with high health management and cooking capacity, while men had the lowest of all the factors (p < 0.001). The group that was low in all three capacity factors had a significantly lower average score of difficulty in acquiring knowledge (reverse), lack of awareness of over- and malnutrition (reverse), importance of weight management, education requirement, knowledge, balanced diet, and health-functional pursuit compared to the other groups (p < 0.001). Conclusion: To effectively manage health, dietary safety management education should be differentiated and actively conducted according to sex, age, cancer diagnosis time, economic status, nutritional supplement intake, and the capacity cluster of cancer survivors.

Analysis of Genetic Polymorphism and Relationship of Korean Ginseng Cultivars and Breeding Lines using EST-SSR Marker (EST-SSR 마커를 이용한 인삼 품종과 육성계통의 유전적 다형성 및 유연관계 분석)

  • Bang, Kyong-Hwan;Seo, A-Yeon;Chung, Jong-Wook;Kim, Young-Chang;Jo, Ick-Hyun;Kim, Jang-Uk;Kim, Dong-Hwi;Cha, Seon-Woo;Cho, Yong-Gu;Kim, Hong-Sig
    • Korean Journal of Medicinal Crop Science
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    • v.20 no.4
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    • pp.277-285
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    • 2012
  • In this study, Expressed Sequence Tag-Simple Sequence Repeat (EST-SSR) analyses were used to clarify the genetic polymorphisms among Korean ginseng cultivars and breeding lines and to classify them into distinct genetic groups. Polymorphic and reproducible bands were produced by 14 primers out of total 30 primers used in this study. Fourteen EST-SSR loci generated a total of 123 bands. Amplified PCR products showed the highly reproducible banding patterns at 110~920 bp. The number of amplified bands for each EST-SSR primers ranged from 2 to 19 with a mean of 8.8 bands. P26 and P35 primers showed 13 and 12 banding patterns, respectively. The number of alleles for each EST-SSR locus ranged from 1.67 to 2.00 with a mean of 1.878 alleles. P34 and P60 primers showed the highest and the lowest genetic polymorphism, respectively. Cluster analysis based on genetic similarity estimated by EST-SSR markers classified Korean cultivars and breeding lines into 4 groups. Group included Gopoong and Chunpoong and 9 breeding lines (55%), group included 2 breeding lines (10%), group included 3 breeding lines (15%), group included Gumpoong and 3 breeding lines (20%). Consequently, the EST-SSR marker developed in this study may prove useful for the evaluation of genetic diversity and differentiation of Korean ginseng cultivars and breeding lines.

Clonorchis Sinensis Control Intervention at a Sumjin Riverside Area (섬진강 유역 일 지역의 간흡충 관리 효과)

  • Park, Myung-Do;Shin, Jun-Ho;Sohn, Seok-Joon;Park, Jong;Kim, Suk-Il
    • Journal of agricultural medicine and community health
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    • v.34 no.1
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    • pp.135-142
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    • 2009
  • Objectives: This study was performed to investigate the changes in the prevalence and its related factors of the Clonorchis sinensis(C.S.) in the inhabitants at Goksung-Gun along Sum-Jin river after C.S. control intervention. Methods: The subjects were 416 among 699 in the 8 same villages selected by stratified cluster sampling in 1999. The formalin-esther sedimentaion technic was used for the C.S. egg detection and the questionnare for the related factors. The study was carried on from February, 2005 to March, 2005. Results: The prevalence of C.S. decreased significantly from 19.0% in 1999 to 11.3% in 2005. The signicicant factors in 1999 such as sex, age, area, raw fish eating habit and drink habit were not significant statistically. On the other hand factors such as the awareness of C.S. and the health behavior were changed significantly(p=0.034, p=0.021). Conclusions: These results suggest that C.S. prevalence became lower than previous study five years ago. But its control intervention should be extened to the general population regardless of sex, age, area, raw fish eating habits, drink habit and we need to make an effort to improve the awareness and the health behavior of C.S..

Microstructure and Magnetic Properties of Zn1-xCoxO Thin Films Grown by Sol-Gel Process (Sol-Gel 법으로 제작한 Zn1-xCoxO 박박의 미세조직 및 자기적 특성)

  • Ko, Yoon-Duk;Tai, Weon-Pil;Kim, Eung-Kwon;Kim, Ki-Chul;Choi, Choon-Gi;Kim, Jong-Min;Song, Joon-Tae;Park, Tae-Seok;Suh, Su-Jeung;Kim, Young-Sung
    • Journal of the Korean Ceramic Society
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    • v.42 no.7 s.278
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    • pp.475-482
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    • 2005
  • Zn$_{l-x}$Co$_{x}$O (x = 0.05 - 0.20) films were grown on Coming 7059 glass by sol-gel process. A homogeneous and stable Zn$_{l-x}$Co$_{x}$O sol was prepared by dissolving zinc acetate dihydrate (Zn(CH$_{3}$COO)$_{2}$$\cdot$2H$_{2}$O), cobalt acetate tetrahydrate ((CH$_{3}$)$_{2}$$\cdot$CHOH) and aluminium chloride hexahydrate (AlCl$_{3}$ $\cdot$ 6H$_{2}$O) as solute in solution of isopropanol ((CH$_{3}$)$_{2}$$\cdot$CHOH) and monoethanolamine (MEA:H$_{2}$NCH$_{2}$CH$_{2}$OH). The films grown by spin coating method were postheated in air at 650°C for 1 h and annealed in the condition of vacuum (5 $\times$ 10$^{-6}$ Torr) at 300$^{\circ}C$ for 30 min and investigated the nature of c-axis preferred orientation and physical properties with different Co concentrations. Znl_xCOxO thin films with different Co concentrations were well oriented along the c-axis, but especially a highly c-axis oriented Zn$_{l-x}$Co$_{x}$O thin film was grown at 10 at$\%$ Co concentration. The transmittance spectra showed that Zn$_{l-x}$Co$_{x}$O thin films occur typical d-d transitions and sp-d exchange interaction became activated with increasing Co concentration. The electrical resistivity of the films at 10 at$\%$ Co had the lowest value due to the highest c-axis orientation. X-ray photoelectron spectroscopy and alternating gradient magnetometer analyses indicated that no Co metal cluster was formed, and the ferromagnetic properties appeared, respectively. The characteristics of the electrical resistivity and room temperature ferromagnetism of Zn$_{l-x}$Co$_{x}$O thin films suggested the possibility for the application to dilute magnetic semiconductors.

miRNA-183 Suppresses Apoptosis and Promotes Proliferation in Esophageal Cancer by Targeting PDCD4

  • Yang, Miao;Liu, Ran;Li, Xiajun;Liao, Juan;Pu, Yuepu;Pan, Enchun;Yin, Lihong;Wang, Yi
    • Molecules and Cells
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    • v.37 no.12
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    • pp.873-880
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    • 2014
  • In our previous study, miRNA-183, a miRNA in the miR-96-182-183 cluster, was significantly over-expressed in esophageal squamous cell carcinoma (ESCC). In the present study, we explored the oncogenic roles of miR-183 in ESCC by gain and loss of function analysis in an esophageal cancer cell line (EC9706). Genome-wide mRNA micro-array was applied to determine the genes that were regulated directly or indirectly by miR-183. 3'UTR luciferase reporter assay, RT-PCR, and Western blot were conducted to verify the target gene of miR-183. Cell culture results showed that miR-183 inhibited apoptosis (p < 0.05), enhanced cell proliferation (p < 0.05), and accelerated G1/S transition (p < 0.05). Moreover, the inhibitory effect of miR-183 on apoptosis was rescued when miR-183 was suppressed via miR-183 inhibitor (p < 0.05). Western blot analysis showed that the expression of programmed cell death 4 (PDCD4), which was predicted as the target gene of miR-183 by microarray profiling and bioinformatics predictions, decreased when miR-183 was over-expressed. The 3'UTR luciferase reporter assay confirmed that miR-183 directly regulated PDCD4 by binding to sequences in the 3'UTR of PDCD4. Pearson correlation analysis further confirmed the significant negative correlation between miR-183 and PDCD4 in both cell lines and in ESCC patients. Our data suggest that miR-183 might play an oncogenic role in ESCC by regulating PDCD4 expression.

Combined Image Retrieval System using Clustering and Condensation Method (클러스터링과 차원축약 기법을 통합한 영상 검색 시스템)

  • Lee Se-Han;Cho Jungwon;Choi Byung-Uk
    • Journal of the Institute of Electronics Engineers of Korea CI
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    • v.43 no.1 s.307
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    • pp.53-66
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    • 2006
  • This paper proposes the combined image retrieval system that gives the same relevance as exhaustive search method while its performance can be considerably improved. This system is combined with two different retrieval methods and each gives the same results that full exhaustive search method does. Both of them are two-stage method. One uses condensation of feature vectors, and the other uses binary-tree clustering. These two methods extract the candidate images that always include correct answers at the first stage, and then filter out the incorrect images at the second stage. Inasmuch as these methods use equal algorithm, they can get the same result as full exhaustive search. The first method condenses the dimension of feature vectors, and it uses these condensed feature vectors to compute similarity of query and images in database. It can be found that there is an optimal condensation ratio which minimizes the overall retrieval time. The optimal ratio is applied to first stage of this method. Binary-tree clustering method, searching with recursive 2-means clustering, classifies each cluster dynamically with the same radius. For preserving relevance, its range of query has to be compensated at first stage. After candidate clusters were selected, final results are retrieved by computing similarities again at second stage. The proposed method is combined with above two methods. Because they are not dependent on each other, combined retrieval system can make a remarkable progress in performance.