• Title/Summary/Keyword: Cluster Center

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Improved Classification Algorithm using Extended Fuzzy Clustering and Maximum Likelihood Method

  • Jeon Young-Joon;Kim Jin-Il
    • Proceedings of the IEEK Conference
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    • summer
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    • pp.447-450
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    • 2004
  • This paper proposes remotely sensed image classification method by fuzzy c-means clustering algorithm using average intra-cluster distance. The average intra-cluster distance acquires an average of the vector set belong to each cluster and proportionates to its size and density. We perform classification according to pixel's membership grade by cluster center of fuzzy c-means clustering using the mean-values of training data about each class. Fuzzy c-means algorithm considered membership degree for inter-cluster of each class. And then, we validate degree of overlap between clusters. A pixel which has a high degree of overlap applies to the maximum likelihood classification method. Finally, we decide category by comparing with fuzzy membership degree and likelihood rate. The proposed method is applied to IKONOS remote sensing satellite image for the verifying test.

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A Unique Gene Expression Signature of 5-fluorouracil

  • Kim, Ja-Eun;Yoo, Chang-Hyuk;Park, Dong-Yoon;Lee, Han-Yong;Yoon, Jeong-Ho;Kim, Se-Nyun
    • Molecular & Cellular Toxicology
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    • v.1 no.4
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    • pp.248-255
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    • 2005
  • To understand the response of cancer cells to anticancer drugs at the gene expression level, we examined the gene expression changes in response to five anticancer drugs, 5-fluorouracil, cytarabine, cisplatin, paclitaxel, and cytochalasin D in NCI-H460 human lung cancer cells. Of the five drugs, 5-fluorouracil had the most distinctive gene expression signature. By clustering genes whose expression changed significantly, we identified three clusters with unique gene expression patterns. The first cluster reflected the up-regulation of gene expression by cisplatin, and included genes involved in cell death and DNA repair. The second cluster pointed to a general reduction of gene expression by most of the anticancer drugs tested. A number of genes in this cluster are involved in signal transduction that is important for communication between cells and reception of extracellular signals. The last cluster represented reduced gene expression in response to 5-fluorouracil, the genes involved being implicated in DNA metabolism, the cell cycle, and RNA processing. Since the gene expression signature of 5-fluorouracil was unique, we investigated it in more detail. Significance analysis of microarray data (SAM) identified 808 genes whose expression was significantly altered by 5-fluorouracil. Among the up-regulated genes, those affecting apoptosis were the most noteworthy. The down-regulated genes were mainly associated with transcription-and translation-related processes which are known targets of 5-fluorouracil. These results suggest that the gene expression signature of an anticancer drug is closely related to its physiological action and the response of caner cells.

Genetic Organization of ascB-dapE Internalin Cluster Serves as a Potential Marker for Listeria monocytogenes Sublineages IIA, IIB, and IIC

  • Chen, Jianshun;Fang, Chun;Zhu, Ningyu;Lv, Yonghui;Cheng, Changyong;Bei, Yijiang;Zheng, Tianlun;Fang, Weihuan
    • Journal of Microbiology and Biotechnology
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    • v.22 no.5
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    • pp.575-584
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    • 2012
  • Listeria monocytogenes is an important foodborne pathogen that comprises four genetic lineages: I, II, III, and IV. Of these, lineage II is frequently recovered from foods and environments and responsible for the increasing incidence of human listeriosis. In this study, the phylogenetic structure of lineage II was determined through sequencing analysis of the ascB-dapE internalin cluster. Fifteen sequence types proposed by multilocus sequence typing based on nine housekeeping genes were grouped into three distinct sublineages, IIA, IIB, and IIC. Organization of the ascB-dapE internalin cluster could serve as a molecular marker for these sublineages, with inlGHE, inlGC2DE, and inlC2DE for IIA, IIB, and IIC, respectively. These sublineages displayed specific genetic and phenotypic characteristics. IIA and IIC showed a higher frequency of recombination (${\rho}/{\theta}$). However, recombination events had greater effect (r/m) on IIB, leading to its high nucleotide diversity. Moreover, IIA and IIB harbored a wider range of internalin and stress-response genes, and possessed higher nisin tolerance, whereas IIC contained the largest portion of low-virulent strains owing to premature stop codons in inlA. The results of this study indicate that IIA, IIB, and IIC might occupy different ecological niches, and IIB might have a better adaptation to a broad range of environmental niches.

Fabrication of Mg Alloy Foam via Melting Foaming Method Using $CaCO_3$ as Blowing Agent ($CaCO_3$를 이용한 발포 마그네슘 합금의 제조)

  • Yang, Dong-Hui;Seo, Chang-Hwan;Wang, Xiao-Song;Hur, Bo-Young
    • Journal of Korea Foundry Society
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    • v.26 no.6
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    • pp.272-276
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    • 2006
  • For the first time AZ91 (MgAl9Zn1) and AM60 (MgAl6) Mg alloy foams with homogeneous pore structures were prepared successfully via melting foaming method by using $CaCO_3$ powder as blowing agent. The possible foaming mechanisms and pore structures of these Mg alloy foams were discussed and investigated. The results show that Mg alloy melt can affect $CaCO_3$ decomposition behavior and AZ91 Mg alloy is relative easy to be foamed into metal foam with high porosity and big pore size.

Kinematic properties of the Ursa Major Cluster

  • Kim, YoungKwang;Lee, Young Sun;Beers, Timothy C.
    • The Bulletin of The Korean Astronomical Society
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    • v.40 no.2
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    • pp.30.3-31
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    • 2015
  • We present a kinematic analysis of 172 likely member galaxies of the Ursa Major Cluster. In order to understand the dynamical state of the cluster, we investigate the correlation of the cluster morphology with rotation, the velocity dispersion profile, and the rotation amplitude parallel to the global rotation direction. Both the minor axis and the rotation are very well-aligned with the global rotation axis in the outer region at half radius (> 0.5 $R_{max}$), but not in the inner region. The cluster exhibits low velocity dispersion and rotation amplitude profiles in the inner region, but higher in the outer. Both profiles exhibit outwardly increasing trends, suggesting an inside-out transfer of angular momentum of dark matter via violent relaxation, as revealed by a recent off-axis major-merging simulation. From Dressler-Schectman plots in the plane of galactic positions, and velocity versus position angle of galaxy, we are able to divide the Ursa Major Cluster into two substructures: Ursa Major South (UMS) and Ursa Major North (UMN). We derive a mass of $3.2{\times}10^{14}M_{\odot}$ for the cluster through the two-body analysis by the timing argument with the distance information (37 for UMN and 36 for UMS) and the spin parameter of ${\lambda}=0.049$. The two substructures appear to have passed each other 4.4 Gyr ago and are moving away to the maximum separation.

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Location-Based Spiral Clustering Algorithm for Avoiding Inter-Cluster Collisions in WSNs

  • Yun, Young-Uk;Choi, Jae-Kark;Yoo, Sang-Jo
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.5 no.4
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    • pp.665-683
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    • 2011
  • Wireless sensor networks (WSN) consist of a large amount of sensor nodes distributed in a certain region. Due to the limited battery power of a sensor node, lots of energy-efficient schemes have been studied. Clustering is primarily used for energy efficiency purpose. However, clustering in WSNs faces several unattained issues, such as ensuring connectivity and scheduling inter-cluster transmissions. In this paper, we propose a location-based spiral clustering (LBSC) algorithm for improving connectivity and avoiding inter-cluster collisions. It also provides reliable location aware routing paths from all cluster heads to a sink node during cluster formation. Proposed algorithm can simultaneously make clusters in four spiral directions from the center of sensor field by using the location information and residual energy level of neighbor sensor nodes. Three logical addresses are used for categorizing the clusters into four global groups and scheduling the intra- and inter-cluster transmission time for each cluster. We evaluated the performance with simulations and compared it with other algorithms.

A HIGH PERFORMANCE CLUSTER FOR ASTRONOMICAL COMPUTATIONS (천문 계산용 고성능 클러스터 구축)

  • KIM JONGSOO;KIM BONG GYU;YIM IN SUNG;BAEK CHANG HYUN;NAM HYUN WOONG;RYU DONGSU;KANG YOUNG WOON
    • Publications of The Korean Astronomical Society
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    • v.19 no.1
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    • pp.77-81
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    • 2004
  • A high performance computing cluster for astronomical computations has been built at Korea Astronomy Observatory. The 64 node cluster interconnected with Gigabit Ethernet is composed of 128 Intel Xeon processors, 160 GB memory, 6 TB global storage space, and an LTO (Linear Tape-Open) tape library. The cluster was installed and has been managed with the Open Source Cluster Application Resource (OSCAR) framework. Its performance for parallel computations was measured with a three-dimensional hydrodynamic code and showed quite a good scalability as the number of computational cells increases. The cluster has already been utilized for several computational research projects, some of which resulted in a few publications, even though its full operation time is less than one year. As a major resource of the $K^*Grid$ testbed, the cluster has been used for Grid computations, too.

Modeling Clustered Interval-Censored Failure Time Data with Informative Cluster Size (군집의 크기가 생존시간에 영향을 미치는 군집 구간중도절단된 자료에 대한 준모수적 모형)

  • Kim, Jinheum;Kim, Youn Nam
    • The Korean Journal of Applied Statistics
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    • v.27 no.2
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    • pp.331-343
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    • 2014
  • We propose two estimating procedures to analyze clustered interval-censored data with an informative cluster size based on a marginal model and investigate their asymptotic properties. One is an extension of Cong et al. (2007) to interval-censored data and the other uses the within-cluster resampling method proposed by Hoffman et al. (2001). Simulation results imply that the proposed estimators have a better performance in terms of bias and coverage rate of true value than an estimator with no adjustment of informative cluster size when the cluster size is related with survival time. Finally, they are applied to lymphatic filariasis data adopted from Williamson et al. (2008).

Multi-scalar Dynamics of Cluster Development: The Role of Policies in Three Korean Clusters (다규모 공간에서 클러스터 발전의 역동성 -한국의 클러스터 사례에서 국가정책의 역할을 중심으로-)

  • Kim, Hyung-Joo;Lee, Jeong-Hyop
    • Journal of the Korean Geographical Society
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    • v.44 no.5
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    • pp.634-646
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    • 2009
  • This paper critically examines cluster dynamics and development in a multi-scalar approach, criticizing both the argument overemphasizing local networks and endogenous development for regional development and the contention highlighting global networks and the role of global players. We argue that state policies, exogenous and direct, play a significant part in cluster dynamics and development especially in the case of Korea where the state government's strong policies have led to rapid industrialization. We analyze multi-scalar factors, especially the government policies at a national level, in the development paths of the three cases including Ulsan automobile cluster, Daedeok research cluster, and Dongdaemun fashion cluster.